LOCUS       NM_172719               8546 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus GCN1 activator of EIF2AK4 (Gcn1), mRNA.
ACCESSION   NM_172719 XM_358358 XM_898512 XM_898519 XM_898526 XM_898531
            XM_898535 XM_913913 XM_994149 XM_994172 XM_994186 XM_994207
            XM_994253 XM_994266 XM_994281
VERSION     NM_172719.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8546)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8546)
  AUTHORS   Liu,J., Kasai,S., Tatara,Y., Yamazaki,H., Mimura,J., Mizuno,S.,
            Sugiyama,F., Takahashi,S., Sato,T., Ozaki,T., Tanji,K.,
            Wakabayashi,K., Maeda,H., Mizukami,H., Shinkai,Y., Kumagai,Y.,
            Tomita,H. and Itoh,K.
  TITLE     Inducible Systemic Gcn1 Deletion in Mice Leads to Transient Body
            Weight Loss upon Tamoxifen Treatment Associated with Decrease of
            Fat and Liver Glycogen Storage
  JOURNAL   Int J Mol Sci 23 (6), 3201 (2022)
   PUBMED   35328622
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8546)
  AUTHORS   Yamazaki,H., Kasai,S., Mimura,J., Ye,P., Inose-Maruyama,A.,
            Tanji,K., Wakabayashi,K., Mizuno,S., Sugiyama,F., Takahashi,S.,
            Sato,T., Ozaki,T., Cavener,D.R., Yamamoto,M. and Itoh,K.
  TITLE     Ribosome binding protein GCN1 regulates the cell cycle and cell
            proliferation and is essential for the embryonic development of
            mice
  JOURNAL   PLoS Genet 16 (4), e1008693 (2020)
   PUBMED   32324833
  REMARK    GeneRIF: Loss of GCN1 causes severe growth retardation and
            embryonic lethality.  GCN1 regulates the eIF2alpha-mediated stress
            response, cell cycle and cell proliferation.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8546)
  AUTHORS   Cambiaghi,T.D., Pereira,C.M., Shanmugam,R., Bolech,M., Wek,R.C.,
            Sattlegger,E. and Castilho,B.A.
  TITLE     Evolutionarily conserved IMPACT impairs various stress responses
            that require GCN1 for activating the eIF2 kinase GCN2
  JOURNAL   Biochem Biophys Res Commun 443 (2), 592-597 (2014)
   PUBMED   24333428
  REMARK    GeneRIF: This study extends our understanding of the roles played
            by GCN1 in GCN2 activation induced by a variety of stress
            arrangements and suggests that IMPACT and YIH1 use similar
            mechanisms for regulating this eIF2alpha kinase.
REFERENCE   5  (bases 1 to 8546)
  AUTHORS   Roffe,M., Hajj,G.N., Azevedo,H.F., Alves,V.S. and Castilho,B.A.
  TITLE     IMPACT is a developmentally regulated protein in neurons that
            opposes the eukaryotic initiation factor 2alpha kinase GCN2 in the
            modulation of neurite outgrowth
  JOURNAL   J Biol Chem 288 (15), 10860-10869 (2013)
   PUBMED   23447528
REFERENCE   6  (bases 1 to 8546)
  AUTHORS   Waller,T., Lee,S.J. and Sattlegger,E.
  TITLE     Evidence that Yih1 resides in a complex with ribosomes
  JOURNAL   FEBS J 279 (10), 1761-1776 (2012)
   PUBMED   22404850
REFERENCE   7  (bases 1 to 8546)
  AUTHORS   Pereira,C.M., Sattlegger,E., Jiang,H.Y., Longo,B.M., Jaqueta,C.B.,
            Hinnebusch,A.G., Wek,R.C., Mello,L.E. and Castilho,B.A.
  TITLE     IMPACT, a protein preferentially expressed in the mouse brain,
            binds GCN1 and inhibits GCN2 activation
  JOURNAL   J Biol Chem 280 (31), 28316-28323 (2005)
   PUBMED   15937339
REFERENCE   8  (bases 1 to 8546)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 8546)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ104712.1, AK147257.1, CD350892.1, AK089324.1, AK077013.1 and
            BY582410.1.
            
            On or before Aug 20, 2006 this sequence version replaced
            XM_913913.2, XM_358358.4, XM_898535.2, XM_898519.2, XM_898531.2,
            XM_898526.2, XM_898512.2, XM_994281.1, XM_994266.1, XM_994253.1,
            XM_994207.1, XM_994186.1, XM_994172.1, XM_994149.1, NM_172719.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090137.1, AK147257.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 CJ104712.1         3-10
            9-1714              AK147257.1         2-1707
            1715-1874           CD350892.1         493-652
            1875-3232           AK147257.1         1868-3225
            3233-4562           AK089324.1         94-1423
            4563-4799           AK147257.1         4556-4792
            4800-6689           AK077013.1         122-2011
            6690-8542           AK147257.1         6683-8535
            8543-8546           BY582410.1         395-398
FEATURES             Location/Qualifiers
     source          1..8546
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 56.1 cM"
     gene            1..8546
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /note="GCN1 activator of EIF2AK4"
                     /db_xref="GeneID:231659"
                     /db_xref="MGI:MGI:2444248"
     exon            1..44
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..8042
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /note="GCN1-like protein 1; translational activator GCN1;
                     GCN1 eIF-2-alpha kinase activator homolog; eIF-2-alpha
                     kinase activator GCN1; GCN1 general control of amino-acid
                     synthesis 1-like 1; general control of amino-acid
                     synthesis 1-like protein 1"
                     /codon_start=1
                     /product="stalled ribosome sensor GCN1"
                     /protein_id="NP_766307.2"
                     /db_xref="CCDS:CCDS19595.1"
                     /db_xref="GeneID:231659"
                     /db_xref="MGI:MGI:2444248"
                     /translation="MAADTQVSETLKRFAVKVTTASVKERREILSELGRCIAGKDLPE
                     GAVKGLCKLFCLTLHRYRDAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGVGSKA
                     CVPSKSSGSAALLALTWTCLLVRIVFPLKAKRQGDIWNKLVEVQCLLLLEVLGGSHKH
                     AVDGAVKKLTKLWKENPGLVEQYFSAILSLEPSQNYAAMLGLLVQFCTNHKEMDAVSQ
                     HKSTLLEFYVKNILMSKAKPPKYLLDNCAPLLRFMSHSEFKDLILPTIQKSLLRSPEN
                     VIETISSLLASVTLDLSQYALDIVKGLANQLKSNSPRLMDEAVLALRNLARQCSDSSA
                     TEALTKHLFAILGGSEGKLTIIAQKMSVLSGIGSLSHHVVSGPSGQVLNGCVAELFIP
                     FLQQEVHEGTLVHAVSILALWCNRFTTEVPKKLTDWFKKVFSLKTSTSAVRHAYLQCM
                     LASFRGDTLLQALDFLPLLMQTVEKAASQGTQVPTVTEGVAAALLLSKLSVADAQAEA
                     KLSGFWQLVVDEKRQTFTSEKFLLLASEDALCTVLRLTERLFLDHPHRLTNSKVQQYY
                     RVLVAVLLSRTWHVRRQAQQTVRKLLSSLGGVKLANGLLDELKTVLNSHKVLPLEALV
                     TDAGEVTEMGKTYVPPRVLQEALCVISGVPGLKGDIPSTEQLAQEMLIISHHPSLVAV
                     QSGLWPALLTRMKIDPDAFITRHLDQIIPRITTQSPLNQSSMNAMGSLSVLSPDRVLP
                     QLISTITASVQNPALCLVTREEFSIMQTPAGELFDKSIIQSAQQDSIKKANMKRENKA
                     YSFKEQIIEMELKEEIKKKKGIKEEVQLTSKQKEMLQAQMDKEAQIRRRLQELDGELE
                     AALGLLDAIMARNPCGLIQYIPVLVDAFLPLLKSPLAAPRVKGPFLSLAACVMPPRLK
                     TLGTLVSHVTLRLLKPECALDKSWCQEELPVAVRRAVSLLHTHTIPSRVGKGEPDAAP
                     LSAPAFSLVFPMLKMVLTEMPYHSEEEEEQMAQILQILTVHAQLRASPDTPPERVDEN
                     GPELLPRVAMLRLLTWVIGTGSPRLQVLASDTLTALCASSSGEDGCAFAEQEEVDVLL
                     AALQSPCASVRETALRGLMELRLVLPSPDTDEKSGLSLLRRLWVIKFDKEDEIRKLAE
                     RLWSTMGLDLQSDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGRLMEI
                     YQEKLYRPPPVLDALGRVISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFFVP
                     DALNDRNPDVRKCMLDAALATLNAHGKENVNSLLPVFEEFLKDAPNDASYDAVRQSVV
                     VLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAVKEDAGGMI
                     QRLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRRE
                     GALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHG
                     VKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHV
                     KVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDA
                     PSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLD
                     PVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAG
                     LGVEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILK
                     ALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDL
                     LFHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVDRRNRVLAGLYMGRSDTQLVV
                     RQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGE
                     KILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLFFSESLVPTARKALCD
                     PLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEEVSEFALDGLKQVMAVKSR
                     VVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLE
                     MANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNMYCSRSKADYSSHL
                     RSLVSGLIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRFIGNECKG
                     EHVPGFCLPKRGVTSILPVLREGVLTGSPEQKEEAAKGLGLVIRLTSADALRPSVVSI
                     TGPLIRILGDRFNWTVKAALLETLSLLLGKVGIALKPFLPQLQTTFTKALQDSNRGVR
                     LKAADALGKLISIHVKVDPLFTELLNGIRAVEDPGIRDTMLQALRFVIQGAGSKVDAA
                     IRKNLVSLLLSMLGHDEDNTRISTAGCLGELCAFLTDEELNTVLQQCLLADVSGIDWM
                     VRHGRSLALSVAVNVAPSRLCAGRYSNEVQDMILSNAVADRIPIAMSGIRGMGFLMKY
                     HIETGSGQLPPRLSSLLIKCLQNPCSDIRLVAEKMIWWANKEPRPPLEPQTIKPILKA
                     LLDNTKDKNTVVRAYSDQAIVNLLKMRRGEELLQSLSKILDVASLEALNECSRRSLRK
                     LACQADSVEQVDDTILT"
     exon            45..147
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            148..211
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            212..343
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            344..452
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            453..551
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            552..686
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            687..755
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            756..864
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            865..939
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1068
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1119
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1218
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1392
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1545
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1638
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1714
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1874
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..2064
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            2065..2189
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2368
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            2369..2462
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..2576
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            2577..2775
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            2776..2931
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..3113
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            3114..3194
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            3195..3338
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            3339..3466
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            3467..3656
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            3657..3727
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            3728..3893
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            3894..4088
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            4089..4335
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            4336..4457
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            4458..4572
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            4573..4752
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            4753..4973
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            4974..5042
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            5043..5181
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            5182..5378
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            5379..5521
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            5522..5639
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            5640..5855
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            5856..6020
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            6021..6182
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            6183..6275
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            6276..6419
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            6420..6689
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            6690..6803
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            6804..7034
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            7035..7228
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            7229..7343
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            7344..7440
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            7441..7589
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            7590..7697
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            7698..7916
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     exon            7917..8546
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8519..8524
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /note="putative"
     polyA_site      8542
                     /gene="Gcn1"
                     /gene_synonym="4932409G22; G431004K08Rik; GCN1L; Gcn1l1;
                     mKIAA0219"
                     /note="putative"
ORIGIN      
        1 gcggttccgg actgggcgcc ggcaggatgg cggcggacac gcaggtttcc gagacactga
       61 agcgcttcgc tgtgaaggtg acaacagcca gtgtgaagga gcggagagag attctcagtg
      121 aactggggcg atgcatcgcc ggcaaagatc tgccagaggg agccgtgaaa gggctctgca
      181 agttgttctg cttgacactg catcgatata gagacgcagc ctctcgcaga gccctgcagg
      241 cagccatcca gcagctggcc gaggcccagc cagaggccac cgccaagaac ctcctgcact
      301 ctctccagtc ttcaggggtt ggctccaaag catgtgttcc cagcaagagt agcggctcag
      361 ctgccttgct ggctctgacc tggacctgcc tcctagtgcg aattgtcttt cccctgaagg
      421 ccaagcggca aggagacatc tggaacaagc tggtggaggt gcagtgcctg ctgctgctgg
      481 aggtgctggg cggctcccac aagcatgctg tggacggtgc tgtgaagaag ctcactaagc
      541 tatggaagga gaaccctggg ctggtggagc agtacttctc agccatcctt agcctggagc
      601 ccagccaaaa ctatgctgcc atgctggggc tgctggtgca gttctgcacg aaccacaaag
      661 agatggacgc ggtcagccag cataagagca ccctgctgga gttctacgtg aagaacattc
      721 tgatgagcaa agccaagcct cccaagtact tgctggacaa ctgtgccccc ttgctccggt
      781 tcatgtccca ctcagagttt aaggatctga ttctgcccac catacagaag tccttgctga
      841 ggagcccaga gaatgttatt gaaactatct ccagcctgct ggcttcagtg acactcgatc
      901 tcagccagta cgccctggac atcgtgaaag gcttggcaaa tcagctgaag tccaacagcc
      961 cccgcctgat ggatgaagcg gtcctggcgc ttcgcaacct ggcccgccag tgcagtgact
     1021 cctccgccac tgaggccctg accaagcacc tgtttgcgat ccttggaggc tcagaaggaa
     1081 agctaaccat catagcccag aagatgagtg tcctttcagg gattggaagc ctcagtcatc
     1141 acgtggtatc ggggccgtcg ggtcaagtcc tgaatggctg tgtggctgag ctgttcatcc
     1201 ccttcctgca gcaggaagtg cacgaaggta ccttggtaca cgccgtctcc atcctggcgc
     1261 tctggtgcaa ccggttcact acagaagtgc ccaagaagct tacggactgg ttcaagaaag
     1321 tcttcagcct taaaacgtcc acctctgcag tgcggcacgc ctacctgcag tgcatgctgg
     1381 cctccttccg aggtgacaca ctgttgcagg ccttggactt tctgccattg cttatgcaga
     1441 cagtagagaa ggcggcctcc cagggcactc aggtccccac agtcaccgaa ggggtcgccg
     1501 cagcccttct gctctccaag ctgtctgtgg ctgacgccca ggccgaggcc aagctgagcg
     1561 gcttttggca gctggttgtg gatgagaaga ggcagacttt cacgtctgag aagttcctgc
     1621 tcctggcttc agaggacgcc ctgtgcactg tgctgcgtct gacggagagg cttttccttg
     1681 accaccctca caggctcacc aacagcaaag tccagcagta ctatcgggtc ctggtggctg
     1741 tgctcctgag ccggacctgg catgtgcgca ggcaggccca gcagacagtt cggaagctgc
     1801 tgtcctctct tgggggtgtt aagctggcca atggtctctt ggacgaactg aagactgtcc
     1861 tcaactctca caaggtgctt cccttggagg ctcttgtgac ggacgctggg gaggtaacgg
     1921 agatgggcaa gacctatgtg cctcctcgag ttctgcagga agctctgtgt gtcatctctg
     1981 gggtgccagg gctcaagggc gacatcccca gcactgagca gctggctcag gagatgctaa
     2041 tcatctccca ccacccgtcc ttagtggcag tacagtctgg actctggcca gcacttctta
     2101 caaggatgaa gattgaccct gacgccttca tcaccaggca cctggatcag atcatcccca
     2161 ggatcacgac acagagtccc ctgaaccagt cttccatgaa cgccatgggc tccctttctg
     2221 tcctgtctcc tgaccgcgtc ctccctcagc tcatcagcac catcactgcc tctgtgcaga
     2281 atcctgccct gtgccttgtg actcgggagg agttctccat catgcagacc cctgccgggg
     2341 agctgtttga taaatccatc atccagagtg cccagcagga cagcataaaa aaggccaaca
     2401 tgaagcgcga gaacaaggcc tactctttta aggagcagat catcgagatg gagctgaagg
     2461 aggaaataaa gaaaaagaaa ggcataaaag aggaggtaca gctgaccagc aagcagaagg
     2521 agatgctgca agcccagatg gacaaggagg cacaaatccg gaggcggctg caggagctgg
     2581 acggggaact agaggcggca cttggactac tagatgccat catggccagg aacccgtgtg
     2641 gcctgattca gtacatccct gtcctggttg atgccttcct gcccttgctg aagtctcccc
     2701 tggctgctcc cagggtcaaa ggcccctttc tgtccttagc tgcctgtgtc atgcccccga
     2761 gactcaagac cttgggcacc ttggtgagtc atgtgaccct gcgcctgctg aagccagagt
     2821 gtgctctgga taagtcctgg tgccaggagg agctgcctgt ggctgtcagg agggcggtgt
     2881 cgctgttgca tacacacacc atccccagca gggtgggcaa gggcgagcca gatgccgccc
     2941 cgctgtctgc accggccttc tccttggtct tccccatgtt aaagatggtg ctcactgaga
     3001 tgccctacca cagcgaggag gaggaggagc agatggccca gatccttcag atcctcactg
     3061 tccatgccca gctgagggcg tcccctgaca ccccacctga gcgggtggac gagaatggcc
     3121 cggagttgct gcctcgagtg gccatgctgc gcctgctgac gtgggtgatc gggacgggct
     3181 cccctcgcct acaggttctt gcctcagaca cgctgactgc cctgtgtgcc agcagcagcg
     3241 gggaggacgg ctgtgccttc gcagagcagg aggaggtgga cgtgctgctt gctgccctgc
     3301 agtccccatg tgccagcgtt cgcgagacag cgctccgggg cctgatggag ctccgcctag
     3361 tactgccatc acccgacact gacgagaaga gtggcctgag cctgttgcgg agactctggg
     3421 tcattaagtt cgacaaggag gatgagatac ggaagctggc cgaaaggctt tggtcaacca
     3481 tgggcctcga tctgcagtca gatctctgct ctttgctgat cgatgacgtg atctatcacg
     3541 aggcagccgt gaggcaggcc ggggctgaag ccctttccca ggcggtggca cggtaccagc
     3601 ggcaggcagc ggaggttatg ggcaggctca tggagatcta ccaggagaag ctctatcggc
     3661 cacccccagt gctggatgct ttgggacgag tgatttcaga atcccctcct gaccagtggg
     3721 aagccaggtg tggcctagcc ttggccctga acaagctctc gcagtacttg gatagctctc
     3781 aggtgaagcc gcttttccag ttctttgtcc cggatgccct gaatgaccgg aacccagatg
     3841 tgcggaagtg catgttagat gcagcgctcg cgacgctcaa tgcccatggg aaggagaatg
     3901 tcaactcact gctgccagtg tttgaggagt tcctgaagga cgcacccaat gatgccagct
     3961 acgacgctgt gcggcagagc gtggtggtcc tcatggggtc tctggccaaa cacctggaca
     4021 agagtgaccc caaagttaaa cctattgttg ccaaactcat tgccgccctc tccacaccct
     4081 ctcagcaggt ccaggagtct gtggccagct gcctgccacc tctcgtgcct gctgtcaagg
     4141 aggatgctgg gggcatgatc cagcggctca tgcagcagct gttggagtcg gacaagtatg
     4201 cggagcgcaa aggggcggca tacgggctgg cgggcctggt caagggcctg ggcatcctct
     4261 ccctgaagca gcaggagatg atggccgcgc tgactgatgc tatccaggac aagaagaact
     4321 tccgaaggcg agagggagcg ctgtttgcct tcgagatgct ctgtaccatg ctggggaagc
     4381 tcttcgagcc ttatgtggtc cacgtgctgc cccatctgtt gctgtgcttt ggggatggga
     4441 accagtacgt gcgcgaggct gcagatgact gtgccaaagc tgtgatgagc aatttgagtg
     4501 ctcacggtgt gaagttggtg ctcccgtcct tgttagctgc cctggaggag gagtcctgga
     4561 ggaccaaagc tgggtccgta gagctgctcg gggcaatggc gtactgtgca cctaagcagc
     4621 tgtcgtcctg cctgcccaac attgtgccca agctcacaga agtgctgaca gactcccacg
     4681 tcaaagtgca gaaggctgga cagcaggccc tcaggcagat tggctctgtc atcagaaacc
     4741 cggagattct cgccattgcc ccggtcctgc tggatgccct gacagaccca tcacggaaga
     4801 cccagaagtg cctgcagacc ctgctggaca ccaagtttgt tcacttcatt gatgccccgt
     4861 ccctggcgct catcatgccc attgtccaga gagccttcca ggaccgctcc acagacacac
     4921 gaaagatggc agcgcagatt attggcaaca tgtactccct gacagaccag aaggacttgg
     4981 ctccttacct gcccagtgtg acacctggcc tgaaagcttc actcttggac cctgtccctg
     5041 aggtgcgcac cgtgtctgca aaggctcttg gggccatggt gaagggcatg ggggagtcgt
     5101 gctttgaaga tttgctgcca tggctgatgg agactctgac gtacgagcag agctccgtgg
     5161 atcgctcagg cgctgcccaa gggttggctg aggtaatggc cggcttagga gtggagaagt
     5221 tggaaaaact gatgccagag atcgtggcca cagccagcaa agtggacatc gcaccccacg
     5281 tccgcgacgg ctacatcatg atgttcaact acctgcccat cacctttggg gacaagttta
     5341 ccccttatgt ggggcccatc atcccttgta tcctcaaggc tctggctgat gagaacgagt
     5401 tcgttcgtga caccgccctg cgtgccggcc agcgggtcat ctcgatgtac gctgagacag
     5461 ctattgccct gctgctgcca cagctagagc aaggcctctt tgatgacctc tggagaatac
     5521 ggttcagctc tgttcaactt cttggggacc tcctgttcca catctctggg gtcacaggga
     5581 agatgaccac ggaaacagcg tctgaggatg ataacttcgg aactgctcag tctaacaagg
     5641 caatcatcac tgccctgggg gttgaccggc ggaaccgggt cctggcggga ctctacatgg
     5701 gccgctcaga cacccagctg gtggtgaggc aggcgtcgct gcacgtgtgg aagattgtcg
     5761 tctccaacac tccccgcacc ctgcgagaga tcctgcccac tctctttggc ctcctactgg
     5821 gtttcctggc tagcacgtgt gcagataaga gaacgatcgc agcgaggacg ctgggcgacc
     5881 tcgtccgcaa gctcggggag aagatccttc ctgagatcat ccccatcctg gaagaaggac
     5941 taaggtcgca gaagagcgac gagaggcagg gcgtgtgcat cgggctcagc gagatcatga
     6001 agtccaccag ccgggacgct gtgctcttct tctctgagtc ccttgtgccc acggcaagga
     6061 aggcgctgtg tgatcccctg gaggaggtcc gggaggcggc agccaagacc tttgagcagc
     6121 tgcactccac cattggccac caggctttgg aggacattct cccgttccta ctgaagcagc
     6181 tggacgacga ggaggtgtcg gaatttgccc tggacggtct gaagcaggtt atggccgtta
     6241 agagccgtgt ggtgctgccc tatctggtgc ccaagctgac aacaccaccc gtcaataccc
     6301 gggtgctggc tttcctgtcc tctgtggctg gcgatgctct gacccgacac cttggcgtga
     6361 tcctcccagc tgtcatgtta gcactgaagg agaagcttgg gactccagac gagcagctgg
     6421 agatggccaa ctgtcaggct gtgatcctct cagtggagga tgacactggg caccggatca
     6481 tcatcgagga tctgttggaa gccacgcgca gccctgaagt gggcatgagg caggcggcgg
     6541 ccatcatcct gaacatgtac tgctcccgct ccaaggccga ctacagcagc caccttcgca
     6601 gcctggtctc gggcttgatc cgcctcttca atgactccag ccctgtggtt ctggaggaga
     6661 gctgggacgc tctcaatgcc atcaccaaga agctggacgc tggtaaccag ctggccctga
     6721 tcgaagaact ccacaaggaa atccgcttca taggcaacga atgcaaaggg gagcacgtgc
     6781 caggcttctg tcttccaaag aggggagtaa cctccatcct tccagtgctg cgggaagggg
     6841 tcctcactgg cagtcctgag cagaaggaag aagcagccaa gggcttgggc ttggtgatcc
     6901 gcctgacctc agctgatgcc ctgaggccct ctgtggtcag catcactggc cctctgattc
     6961 gcatccttgg ggaccggttc aactggactg tgaaggcggc tctgctggag acactcagcc
     7021 tcttgctggg caaggttggg attgccctga agcccttcct gccccagctt cagaccacct
     7081 tcaccaaagc cctacaggac tccaatcggg gcgtccggct gaaggcggcc gatgctctgg
     7141 ggaagctcat ttccatccac gtcaaggtgg accccctctt tacagagctg ctcaacggca
     7201 tccgcgcggt ggaggacccg ggcatacgag acaccatgtt gcaggccctg aggtttgtga
     7261 ttcagggtgc aggctccaaa gtggatgctg ccattcggaa aaacctggtc tcgctcctgc
     7321 tgagcatgct gggccatgac gaggacaaca ctcggatctc cacagctggg tgccttgggg
     7381 aactgtgtgc ctttctgact gacgaagagc tcaacactgt ccttcagcag tgcctgctag
     7441 ctgacgtatc tggcattgac tggatggttc ggcacggccg gagcttggcg ctgtccgtgg
     7501 ctgtgaatgt ggctcccagc agactgtgtg caggcagata cagcaatgag gttcaggaca
     7561 tgatcctcag caacgccgtg gcagacagga tccccatcgc catgagtggg attcgaggca
     7621 tgggcttcct catgaagtat cacatcgaga caggaagcgg gcagctgccc cccaggctct
     7681 ccagccttct catcaagtgt ctgcagaacc catgtagtga catcaggctg gtggccgaga
     7741 agatgatctg gtgggcaaac aaggagcccc ggccccccct ggagccacag accatcaagc
     7801 ccatcctgaa ggctcttctc gataacacca aggacaagaa cactgtcgtg cgggcctaca
     7861 gcgaccaggc catcgtgaac ctgctcaaga tgaggcgggg cgaggagctg ctccagtccc
     7921 tctccaagat cctggacgtg gccagcctgg aggctctgaa tgaatgcagc cggaggtcgc
     7981 tgaggaagct ggcctgccag gcagactcgg tggagcaggt ggacgacacc atcctgacgt
     8041 gacaggctgg tcccgccagc cgcagccacg ctgcccctcg tctgtgttca cactgttttc
     8101 atttttgaaa atacttttat tccaaggggg agctcaggag atggcattcc cagaaagtat
     8161 tttagtacat caagcgacca gagccaaagc cttaaatcca acccacacac aactgaagat
     8221 cgcctcctcc ctctcttgcc cttatctcca gagaagagaa agagaagcgt gcacaccacc
     8281 ctcagcgagc ggcagcaagg ggagcccgac tcggctcagc ccggatggac gaactcgggc
     8341 cctcctttac ttgggaggcc tgtgtctgag ggcattgagc ggggcatcag tgctgcctga
     8401 tgctgcgcct ggctttctgg gcggcctgac tctacctggc ttgtctggag aagaggctgc
     8461 ccagtcctcc tcctcctcag ctccggggct tggggtacag gccattcgaa ggaggtttaa
     8521 taaaggcttt gatttcatct tgaaag
//
