LOCUS       NM_008103               2034 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus glial cells missing homolog 1 (Gcm1), mRNA.
ACCESSION   NM_008103
VERSION     NM_008103.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2034)
  AUTHORS   Fan,W., Li,Z., He,X., Wang,X., Sun,M. and Yang,Z.
  TITLE     SLC25A1 regulates placental development to ensure embryonic heart
            morphogenesis
  JOURNAL   Development 151 (22) (2024)
   PUBMED   39591637
REFERENCE   2  (bases 1 to 2034)
  AUTHORS   Zhu,Z., Zou,Q., Wang,C., Li,D., Yang,Y., Xiao,Y., Jin,Y., Yan,J.,
            Luo,L., Sun,Y. and Liang,X.
  TITLE     Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors
            and is Required for Placenta Morphogenesis and Vasculature
            Formation
  JOURNAL   Adv Sci (Weinh) 11 (32), e2400238 (2024)
   PUBMED   38923264
REFERENCE   3  (bases 1 to 2034)
  AUTHORS   Zheng,W., Zhang,Y., Xu,P., Wang,Z., Shao,X., Chen,C., Cai,H.,
            Wang,Y., Sun,M.A., Deng,W., Liu,F., Lu,J., Zhang,X., Cheng,D.,
            Mysorekar,I.U., Wang,H., Wang,Y.L., Hu,X. and Cao,B.
  TITLE     TFEB safeguards trophoblast syncytialization in humans and mice
  JOURNAL   Proc Natl Acad Sci U S A 121 (28), e2404062121 (2024)
   PUBMED   38968109
REFERENCE   4  (bases 1 to 2034)
  AUTHORS   Lee,J.G., Yon,J.M., Kim,G., Lee,S.G., Kim,C.Y., Cheong,S.A.,
            Kim,H.Y., Yu,J., Kim,K., Sung,Y.H., Yoo,H.J., Woo,D.C., Rho,J.K.,
            Ha,C.H., Pack,C.G., Oh,S.H., Lim,J.S., Han,Y.M., Hong,E.J.,
            Seong,J.K., Lee,H.W., Lee,S.W., Lee,K.U., Kim,C.J., Nam,S.Y.,
            Cho,Y.S. and Baek,I.J.
  TITLE     PIBF1 regulates trophoblast syncytialization and promotes
            cardiovascular development
  JOURNAL   Nat Commun 15 (1), 1487 (2024)
   PUBMED   38374152
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2034)
  AUTHORS   Astrof,S., Arriagada,C., Saijoh,Y., Francou,A., Kelly,R.G. and
            Moon,A.
  TITLE     Aberrant differentiation of second heart field mesoderm prefigures
            cellular defects in the outflow tract in response to loss of FGF8
  JOURNAL   Dev Biol 499, 10-21 (2023)
   PUBMED   37060937
REFERENCE   6  (bases 1 to 2034)
  AUTHORS   Basyuk,E., Cross,J.C., Corbin,J., Nakayama,H., Hunter,P.,
            Nait-Oumesmar,B. and Lazzarini,R.A.
  TITLE     Murine Gcm1 gene is expressed in a subset of placental trophoblast
            cells
  JOURNAL   Dev Dyn 214 (4), 303-311 (1999)
   PUBMED   10213386
REFERENCE   7  (bases 1 to 2034)
  AUTHORS   Hunter,P.J., Swanson,B.J., Haendel,M.A., Lyons,G.E. and Cross,J.C.
  TITLE     Mrj encodes a DnaJ-related co-chaperone that is essential for
            murine placental development
  JOURNAL   Development 126 (6), 1247-1258 (1999)
   PUBMED   10021343
REFERENCE   8  (bases 1 to 2034)
  AUTHORS   Kim,J., Jones,B.W., Zock,C., Chen,Z., Wang,H., Goodman,C.S. and
            Anderson,D.J.
  TITLE     Isolation and characterization of mammalian homologs of the
            Drosophila gene glial cells missing
  JOURNAL   Proc Natl Acad Sci U S A 95 (21), 12364-12369 (1998)
   PUBMED   9770492
REFERENCE   9  (bases 1 to 2034)
  AUTHORS   Akiyama,Y., Hosoya,T., Poole,A.M. and Hotta,Y.
  TITLE     The gcm-motif: a novel DNA-binding motif conserved in Drosophila
            and mammals
  JOURNAL   Proc Natl Acad Sci U S A 93 (25), 14912-14916 (1996)
   PUBMED   8962155
REFERENCE   10 (bases 1 to 2034)
  AUTHORS   Altshuller,Y., Copeland,N.G., Gilbert,D.J., Jenkins,N.A. and
            Frohman,M.A.
  TITLE     Gcm1, a mammalian homolog of Drosophila glial cells missing
  JOURNAL   FEBS Lett 393 (2-3), 201-204 (1996)
   PUBMED   8814290
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC160334.2.
            
            On Nov 17, 2006 this sequence version replaced NM_008103.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066866.1, U59876.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                AC160334.2         141913-141995
            84-263              AC160334.2         143767-143946
            264-516             AC160334.2         149531-149783
            517-629             AC160334.2         151303-151415
            630-758             AC160334.2         152366-152494
            759-2034            AC160334.2         154304-155579
FEATURES             Location/Qualifiers
     source          1..2034
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 43.49 cM"
     gene            1..2034
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /note="glial cells missing homolog 1"
                     /db_xref="GeneID:14531"
                     /db_xref="MGI:MGI:108045"
     exon            1..83
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /inference="alignment:Splign:2.1.0"
     exon            84..263
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /inference="alignment:Splign:2.1.0"
     CDS             189..1499
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /note="mGCM1; mGCMa; GCM motif protein 1; Gcm 1; Gcm a;
                     glial cell deficient"
                     /codon_start=1
                     /product="chorion-specific transcription factor GCMa"
                     /protein_id="NP_032129.2"
                     /db_xref="CCDS:CCDS23356.1"
                     /db_xref="GeneID:14531"
                     /db_xref="MGI:MGI:108045"
                     /translation="MELDDFDPEDKEILSWDINDVKLPQNVKTTDWFQEWPDSYVKHI
                     YSSDDRNAQRHLSSWAMRNTNNHNSRILKKSCLGVVVCSRDCSTEEGRKIYLRPAICD
                     KARQKQQRKSCPNCNGPLKLIPCRGHGGFPVTNFWRHDGRFIFFQSKGEHDHPRPETK
                     LEAEARRAMKKVHMASASNSLRMKGRPAAKALPAEIPSQGSLPLTWSFQEGVQLPGTY
                     STPLIANAPQQNSLNDCLSFPKSYDLGGSTELEDPTSTLDSMKFYERCKFSSSRIYGS
                     EEQFQPPVPGTYGDYEDLQTWNKNVALGRNPSDDIYYPAYPLPVASWPYDYFPSQNSL
                     EHLPQQVPSEPPAAQPGCHPLWSNPGGEPYEEKVSVDLSSYVPSLTYHPPQQDPFLLT
                     YGSPTQQQHALPGKSNRWDFDEEMACMGLDHFNNEMLLNFCSLR"
     exon            264..516
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /inference="alignment:Splign:2.1.0"
     exon            517..629
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /inference="alignment:Splign:2.1.0"
     exon            630..758
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /inference="alignment:Splign:2.1.0"
     exon            759..2034
                     /gene="Gcm1"
                     /gene_synonym="Gcm-rs2; Gcm1-rs1; GCMa; glide"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgagccaga gctgacactt gtatgacacc tggacaagaa gctgacaaga aggacagact
       61 cgggagcact gaaggcggac aggctttgaa aaacaagccc ttcagctgct cttgtggccc
      121 gagttctgag actccaaata gctctgacaa ctggagtaga gaagagcctg tgttgagcag
      181 accttatcat ggaactggac gactttgatc ctgaagacaa agagatactg agctgggaca
      241 ttaacgatgt gaaactgcct cagaacgtga aaacgactga ctggttccag gagtggccgg
      301 actcctacgt gaaacacatc tacagctcgg acgacaggaa cgcacagcgc cacctgagca
      361 gctgggccat gcgcaacacc aacaaccaca actcccggat cctcaagaag tcatgcctgg
      421 gggtagtggt gtgcagcagg gactgctcca cagaggaagg ccgcaagatt tacctgagac
      481 ccgccatctg tgacaaagcc agacagaagc agcagaggaa aagctgtccc aactgcaatg
      541 gacccctgaa gcttattccc tgccgaggcc acggcggctt cccggtcacc aacttctgga
      601 ggcacgacgg acgcttcatc tttttccagt ccaaaggcga gcatgatcat cccaggccgg
      661 agaccaagct ggaagcagag gcaagaagag ccatgaagaa agtgcacatg gcatctgcct
      721 ccaactcctt acggatgaag gggagaccag cagcgaaggc gcttcctgct gaaatcccga
      781 gtcagggaag tttaccttta acttggtcat tccaggaagg cgtccaactg cccggcactt
      841 acagcacacc tttaatagct aacgcccccc agcagaactc cctgaatgat tgcttatcct
      901 tccccaagag ttatgatttg gggggaagca ctgagctgga agatccaact tccaccttag
      961 attccatgaa gttctatgag agatgcaaat tctccagcag taggatctac ggcagtgaag
     1021 agcagtttca gcctcctgtc cctgggacgt atggagacta cgaagacctg caaacttgga
     1081 ataaaaatgt tgccttaggg agaaatccct ccgatgacat ctactatcca gcctatcctc
     1141 tgcctgtggc cagctggccc tacgactact ttccctccca gaactctttg gagcacttac
     1201 cccagcaagt tccatcagaa ccccctgcag ctcaaccagg ctgtcatccc ttgtggtcca
     1261 atccgggagg tgagccttac gaagagaaag tatctgtgga tctgagcagc tatgtgccct
     1321 ccctcacgta ccacccacct cagcaggatc ccttcctgct cacctatggc tctcctactc
     1381 agcagcaaca tgcactgccc ggcaagagca acaggtggga ttttgacgaa gagatggcat
     1441 gcatgggctt agatcacttc aacaatgaga tgctcctaaa cttctgttct ttaagataac
     1501 tcaaagctcc ccttctctct cccagtcgtg atttgttaaa gggcttggca gaattttctt
     1561 agaagacggg tttcaaagca tagcctgaga ggaatgttgg aatcaattgt gacaagcagt
     1621 agacaaggtc ttctcactca agctgttgac aatgccagtg tgtttaccct ccataaggaa
     1681 tagaaagtca ccgtgccagg tgtaatgtca caagtctcta atcccggcac tcaggagaca
     1741 gaggcagttg gatatttgtg agttcaaggc cagccgagtt tacatactga gttccaggag
     1801 agccaggact atgtagagag accctgtctc aacacctccc cccacaaaag aagaagaaga
     1861 agaagaagaa gaagaagaag aagaagaaga agaagaagaa gaagaagagg aagaggaaga
     1921 ggaagaggaa gaggaagagg aagaggaaga ggaagaggaa gaggaagagg aagaggaaga
     1981 ggaagaggag gagaaggagg aggaggagga aaaggaggag gaggagaaag aaga
//
