LOCUS       NM_027375               6530 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Mus musculus GRIP and coiled-coil domain containing 2 (Gcc2),
            transcript variant 1, mRNA.
ACCESSION   NM_027375 XM_358303
VERSION     NM_027375.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6530)
  AUTHORS   Tu,X., Chu,T.T., Jeltema,D., Abbott,K., Yang,K., Xing,C., Han,J.,
            Dobbs,N. and Yan,N.
  TITLE     Interruption of post-Golgi STING trafficking activates tonic
            interferon signaling
  JOURNAL   Nat Commun 13 (1), 6977 (2022)
   PUBMED   36379959
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6530)
  AUTHORS   Clapp,J., Mitchell,L.M., Bolland,D.J., Fantes,J., Corcoran,A.E.,
            Scotting,P.J., Armour,J.A. and Hewitt,J.E.
  TITLE     Evolutionary conservation of a coding function for D4Z4, the tandem
            DNA repeat mutated in facioscapulohumeral muscular dystrophy
  JOURNAL   Am J Hum Genet 81 (2), 264-279 (2007)
   PUBMED   17668377
REFERENCE   3  (bases 1 to 6530)
  AUTHORS   Papin,J. and Subramaniam,S.
  TITLE     Bioinformatics and cellular signaling
  JOURNAL   Curr Opin Biotechnol 15 (1), 78-81 (2004)
   PUBMED   15102471
  REMARK    Review article
REFERENCE   4  (bases 1 to 6530)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   5  (bases 1 to 6530)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Hara,Y., Nagase,T.,
            Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: I. The complete nucleotide sequences of 100 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 9 (5), 179-188 (2002)
   PUBMED   12465718
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC170751.2.
            
            On Jun 8, 2022 this sequence version replaced NM_027375.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC139007.1, AB093232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                AC170751.2         49642-49706
            66-119              AC170751.2         49964-50017
            120-204             AC170751.2         50955-51039
            205-272             AC170751.2         52376-52443
            273-377             AC170751.2         62102-62206
            378-2822            AC170751.2         63397-65841
            2823-2895           AC170751.2         66468-66540
            2896-2996           AC170751.2         68871-68971
            2997-3095           AC170751.2         69071-69169
            3096-3215           AC170751.2         70713-70832
            3216-3380           AC170751.2         72922-73086
            3381-3485           AC170751.2         74727-74831
            3486-3648           AC170751.2         75492-75654
            3649-3749           AC170751.2         80078-80178
            3750-3827           AC170751.2         80268-80345
            3828-3965           AC170751.2         81277-81414
            3966-4087           AC170751.2         82768-82889
            4088-4264           AC170751.2         84435-84611
            4265-4482           AC170751.2         86700-86917
            4483-4677           AC170751.2         88846-89040
            4678-4829           AC170751.2         90223-90374
            4830-5031           AC170751.2         92799-93000
            5032-6530           AC170751.2         98229-99727
FEATURES             Location/Qualifiers
     source          1..6530
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 29.3 cM"
     gene            1..6530
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /note="GRIP and coiled-coil domain containing 2"
                     /db_xref="GeneID:70297"
                     /db_xref="MGI:MGI:1917547"
     exon            1..65
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..5102
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /note="GCC185; 185 kDa Golgi coiled-coil protein"
                     /codon_start=1
                     /product="GRIP and coiled-coil domain-containing protein
                     2"
                     /protein_id="NP_081651.2"
                     /db_xref="CCDS:CCDS23859.1"
                     /db_xref="GeneID:70297"
                     /db_xref="MGI:MGI:1917547"
                     /translation="MEDSAPDAVAAAPSGTPKSKLETLPREDLIKFAKKQMMLLQKAK
                     ARCTELDKEVEELKSKPVDGGTDDIIKVLTERLDALLLEKAETEQQCLCLKKENVKMK
                     QEVEDSVTKLEETHKEFEQSHRNYVKEIESCKNELMAVHSEHSKETAILQKELEEAVH
                     KQVELREQLKSQSDSEDNVRKLQEEIQNITAAFEEQISCLEKKLEATSDEKQQEIIHL
                     QKVIEDKAQHYQKDINTFQAEILQLRATHKEEVTELMSQIETSAKEHEAEINKLKENR
                     VTQCEASENIPEKYQCESENLNEVASDASPESQNCSVALQEDPSAEQTVCDKVRQLED
                     SLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQ
                     GYVVEKLKYEREDLNRQLCCAVEQHNKEIQRLQEHHQKEVSELSETFISGSEKEKLAL
                     MFEIQGLKEQCENLQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQQA
                     SDVHELQQKLRSAFNEKDALLETVNRLQGENEKLLSQQELVPELESTIKNLQADNSMY
                     LASLGQKDTMLQELEAKISSLAKEKDDFISKIKTSHEEMDDLHQKWEREQRLSVELRE
                     AAGQAAQHNSELRQRVSELTGKLDELVREKSQNDQSITVQMKTMTEDQEALSSKIKSL
                     YEENNRLHSEKAQLSRDLEALQAQQDFAHKEHVAEFEKKLQLMVEERDDLNKLLENEQ
                     VQKSFVKTQLYEYLKQLRASILEENEEEDVVKLIQAVGESLVKVKEEEHNLVFEYDAR
                     VLELENKIKCLQEDSAVQCEELRTLVRDSEQEKILLRKELDAVTSAKEALQLDLLEMK
                     NTNEKASLENQTLSTQVEELSQTLHSRNEVHDEKVLVIEHENLRLLLKQRESELQDVR
                     AELILLKDSLEKSPSVKNDQLSLVKELEEKIESLEKESKDKDEKISKIKLVAVKAKKE
                     LDSNRKEAQTLREELESVRSEKDRLSASMKEFLQGAESYKSLLLEYDKQSEQLDVEKE
                     RAHNFERHIEDLTKQLRNSTCQYERLTSDNEDLLARIETLQANAKLLEAQILEVQKAK
                     GVVEKELDAEKLQKEQKIKEHVSTVNELEELQLQFQKEKKQLQKTMQELELVKKDAQQ
                     TTLMNMEIADYERLMKELNQKLTNKNSTIEDLEQEMKIQKEKQETLQEEITSLQSSVQ
                     HYEEKNTKIKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKIQLAEM
                     TSEKHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRAAKAEQAAVTSEFESYKVRVH
                     NVLKQQKNKSVSQVETEGAKQEREHLEMLIDQLKIKLQDSQNSLQISVSEYQTLQAEH
                     DTLLERHNRMLQETVTKEAELREKLCSVQSENTMMKSEHSQTMCQLTSQNEALRTSFR
                     DQVRHLQDEHRKTVETLQHQLSKLEAQLFQLKSEPSTRSPASSHQPSKSLRERRTTDL
                     PLLDMHTVAREEGEGMETTDSESVSSAGTHIQSLEQLLSSPDTKLERLAETSLWHNEF
                     TKEELAEKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSVA
                     NLEYLKNVLLRFIFLKPGSERERLLPVIDTMLQLSPEEKGKLATVAQGEEESASRSSG
                     WASYLHSWSGLR"
     exon            66..119
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            120..204
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            205..272
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            273..377
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            378..2822
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            2823..2895
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            2896..2996
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            2997..3095
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3096..3215
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3216..3380
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3381..3485
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3486..3648
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3649..3749
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3750..3827
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3828..3965
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            3966..4087
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            4088..4264
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            4265..4482
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            4483..4677
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            4678..4829
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            4830..5031
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     exon            5032..6530
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6511..6516
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /note="hexamer: ATTAAA"
     polyA_site      6530
                     /gene="Gcc2"
                     /gene_synonym="0610043A03Rik; 2210420P05Rik;
                     2600014C01Rik; mKIAA0336"
                     /note="major polyA site"
ORIGIN      
        1 aggcggagca gccgagactc ctgaagaggc ggtggaggca gccgcgggtc gcagccgcga
       61 tggaggattc tgctccagat gccgtagctg cagcaccctc cgggaccccg aaatccaagc
      121 tagaaacgtt gcccagagaa gatctcatca agtttgccaa gaagcaaatg atgctcctgc
      181 agaaagccaa agcaaggtgt acagaattag acaaagaagt tgaagaactc aaatcaaaac
      241 ctgttgatgg aggaactgat gatattatta aggtactaac tgaacgcttg gatgctcttc
      301 ttctggaaaa agcagagact gaacaacagt gtctatgtct gaaaaaagaa aatgttaaaa
      361 tgaagcaaga ggttgaggat tctgtaacta aactggaaga gacacacaaa gagtttgaac
      421 aatcacatag aaactacgta aaagaaattg aaagctgtaa aaatgagctg atggcagtgc
      481 actcagagca cagcaaagaa acggccatct tacaaaaaga actggaagaa gctgtccata
      541 agcaagtaga gctgagagag cagcttaagt ctcagagtga ctctgaagat aacgtgagaa
      601 aactgcagga agagattcaa aacatcacag cagcatttga ggaacagatt tcatgtctag
      661 agaagaaatt agaagctacc agtgatgaaa aacaacaaga gattattcat ctccagaaag
      721 tcattgagga caaggctcag cactaccaaa aagatattaa tactttccaa gcagagattt
      781 tgcagctgag agctacacac aaagaagaag ttactgagct gatgtctcaa atagaaacat
      841 cagctaaaga acacgaggca gaaataaata aactaaaaga gaacagagtg acacagtgtg
      901 aggcaagtga gaacattcca gagaaatacc aatgtgaatc ggaaaactta aatgaagtcg
      961 cctcagatgc aagcccggag agtcagaatt gctctgtggc cttacaggaa gatccttctg
     1021 cggaacaaac agtatgtgat aaagtcagac aattggaaga ttcattaaaa gaactggaat
     1081 ctcaacatag tatcttaaaa gatgaagtaa cttatatgaa taatctcaag ttaaaacttg
     1141 aaatggatgc ccagcatata aaggatgagt ttttccatga acgagaagac ttagagttta
     1201 aaattaatga actgttgctg gctaaagaag aacagggcta tgtagtagaa aaattaaaat
     1261 atgagcgaga agatttaaat aggcaacttt gctgtgctgt ggaacaacat aacaaagaaa
     1321 tacagcgtct tcaggaacac catcagaaag aagtctctga actaagtgag acatttatat
     1381 caggttcaga aaaagaaaag ttagcattga tgtttgaaat acaaggtctt aaggaacagt
     1441 gtgaaaatct acaacatgaa aagcaagagg tagttctaaa ctatgagagt ttacgagaga
     1501 tgatggaaat tttacaaaca gaacttggag aatctgctgg aaaaataagt caagagtttg
     1561 aaacaatgaa gcaacagcaa gcatctgatg ttcatgagct tcagcagaag ctaagaagtg
     1621 cttttaatga aaaagatgct cttcttgaaa ctgtgaatcg cctccaagga gaaaatgaaa
     1681 aattattatc tcaacaagaa ttagtaccag aacttgaaag taccataaag aaccttcagg
     1741 cagataatag catgtactta gccagtcttg gtcaaaaaga taccatgtta caagaattag
     1801 aagcaaagat aagttctctt gctaaagaaa aagatgactt tataagtaaa atcaaaactt
     1861 cccatgaaga gatggatgat ctccatcaga aatgggaaag ggaacagaga ctgtctgtag
     1921 aactcaggga agcagcaggg caagctgccc agcacaacag tgaactgaga caaagagtaa
     1981 gtgaattaac agggaaacta gatgaactag taagagaaaa gagtcaaaat gaccaaagca
     2041 ttacggttca aatgaaaact atgacggaag atcaagaagc tctgtcatct aaaatcaagt
     2101 ctctttatga ggaaaacaat agactacatt cagaaaaggc ccagttgagc agggatttag
     2161 aagcacttca ggctcaacaa gattttgccc ataaagaaca tgttgctgaa ttcgaaaaga
     2221 aactccagtt aatggttgag gagcgagacg atttaaataa actgcttgaa aatgagcaag
     2281 ttcagaagtc atttgttaaa actcagttgt atgagtatct taagcaactg agggcaagca
     2341 ttttagaaga aaatgaagag gaagatgttg tcaaacttat acaagctgta ggtgaatctt
     2401 tagtgaaagt aaaggaagaa gaacataact tagtctttga atatgatgca agggtattag
     2461 aattagaaaa taagattaag tgtcttcaag aggacagtgc agttcagtgt gaagaactaa
     2521 ggactttagt aagagactct gagcaagaga aaattctcct aagaaaagaa ttagatgcag
     2581 tcacatcagc aaaagaggcc ctccaacttg atcttttaga aatgaagaat actaatgaga
     2641 aagcaagcct tgaaaaccag actctttcaa ctcaggttga agaattatct cagacattac
     2701 acagcagaaa tgaagtccat gatgaaaagg ttcttgtaat agaacatgaa aacctaaggc
     2761 tactgcttaa acagagggaa tctgaactcc aagatgtgag agcagaattg atactgctaa
     2821 aggattcctt agagaaatcg ccttctgtaa aaaatgatca actttcattg gtaaaagagc
     2881 tggaagaaaa aatagaaagt ctggaaaaag aatccaaaga caaggatgag aaaataagta
     2941 agataaaact agttgctgtg aaagcaaaga aagaactaga ttctaacagg aaagaggccc
     3001 agacactacg ggaagaactg gaatccgtgc ggtcagaaaa ggaccgcctg tctgcttcta
     3061 tgaaggagtt cctccaagga gcagagagct ataagagtct tctgttagaa tatgataagc
     3121 agtcagaaca gctggatgtg gaaaaagaac gtgctcataa ttttgaacgt catatagaag
     3181 accttaccaa acaattaaga aattcgactt gccagtatga aagactaact tcagacaacg
     3241 aggatctcct ggctcgaatt gagaccctgc aggctaatgc caagttgtta gaagcacaga
     3301 tcttagaagt ccagaaagcc aaaggagtag tagaaaaaga actggacgct gaaaaacttc
     3361 agaaagagca gaaaattaag gaacatgtca gtactgtaaa tgagctcgaa gaactccaac
     3421 tccaatttca aaaggaaaag aagcagcttc agaaaacaat gcaagaatta gagctggtta
     3481 aaaaggatgc ccaacagacc acattgatga atatggaaat agcagattac gaacgtttga
     3541 tgaaagaact aaatcaaaag ttaacaaata aaaacagtac aatagaagat ttggagcaag
     3601 aaatgaaaat tcagaaagag aaacaagaaa ccctacaaga agaaataact tcactgcagt
     3661 cgtcagtaca gcactatgaa gaaaagaaca ctaaaatcaa gcagctgctt gtgaaaacca
     3721 aaaaggagct ggcagatgca aagcaagcgg aaaccgatca cttactactc caggcatctt
     3781 taaagggtga gctggaagca agccagcagc aagtagaagt ctataaaatt cagctggctg
     3841 agatgacatc tgagaaacac aaaatccatg agcatctgaa gacttctgcg gaacagcacc
     3901 agcgcacact gagtgcatac cagcagaggg tggtggccct gcaggaggag agtcgcgctg
     3961 ccaaggcaga acaagctgct gtcacctctg aatttgagag ctacaaagtc cgagttcata
     4021 acgttctaaa gcaacagaaa aataaatctg tgtctcaggt tgaaactgag ggagctaaac
     4081 aagaaaggga acacctggaa atgctgattg accaactgaa aatcaagtta caggacagcc
     4141 aaaatagctt acaaatcagt gtatcggagt accagaccct gcaggctgag cacgacactc
     4201 tgctagagag gcacaaccgg atgctgcagg aaactgtgac caaagaggca gaacttcggg
     4261 aaaagctatg ttcagttcaa tctgagaaca ccatgatgaa gtctgagcac tcgcagacaa
     4321 tgtgtcagct aacatcccag aatgaagcac tccgtaccag cttccgagac caagttcgac
     4381 acttgcagga tgagcacaga aagacagtgg agactctgca gcaccagctc tccaagctgg
     4441 aagctcagct cttccagctc aagagtgagc catccacaag aagccctgct tcttcccatc
     4501 aaccttcgaa aagcctccga gaaagaagaa ccacagacct cccccttctg gacatgcaca
     4561 ctgtggcccg cgaggagggg gagggcatgg agacaactga cagcgagtct gtgtcgtcgg
     4621 caggcacaca cattcagtcc ttagagcagc tccttagctc tcctgacacc aagcttgaac
     4681 gccttgcaga gacctccttg tggcataatg aatttaccaa agaagaatta gctgagaagc
     4741 tcagctccac cacgaagagt gcagatcact taaacggcct gcttcgggag acagaggcta
     4801 ccaacgctat ccttatggag caaattaagc ttctcaagag tgaaataaga agactggaaa
     4861 gaaaccaaga gcgtgagaag tctgtggcta acctggagta cttgaagaat gtcttgctgc
     4921 ggttcatttt cctgaagccg ggtagtgaaa gagagaggct tctgcctgtg atagacacca
     4981 tgctgcagct cagccctgag gaaaagggaa agcttgccac agttgctcaa ggtgaggaag
     5041 aaagtgcttc tcgttcctct ggatgggcgt cctatctgca tagctggtct ggactgcgat
     5101 agagcgacag aaggaaggtt ctttagtgac tcaacgcaat tcctttggga aaaagtggtt
     5161 atcattattt gatgaggaag tgtgcatatc tgttcccatc ccctgatgag tgtatatatg
     5221 tatagcccac gtatttagaa tctcatccta tagtaaaagg aaacagcttg aagcaatggt
     5281 accaattgtc cagggccctc taacccagca cgtggcctca caggctctgt gatctccgtc
     5341 cacagaggaa acagttcatt cctgcacttg gaaccccagg agacactggt ttctaagtag
     5401 tactgtgaat tttgatgtta aactaaattt tggtaccata ccaactgggg aattaatctt
     5461 ttaaaataat gtttcaagat tgaggaaatg ctttttggta aggttgccgt gtttattaaa
     5521 ggattatgaa gcaaatatgc tatggttaat tatgaggcta agttaaattg taattcagtc
     5581 agttgcttta aaataaggcc cctctcccat ttgttatttt caaacttggc cctagtcctg
     5641 gtgatgtggc actgactgaa taggtgggcc cacctcagct ggtgtgtttc tatagtgtcc
     5701 caggctgtgt gccgccacta ctcctaagcc atgagtcggt ttgagaatcc ctacatctcg
     5761 aaacagtgac tgtcttactc agcattaaat ccacatgtga acctggtgct tccagtattg
     5821 ttcagggaga cttatttcct aagcatgacc ccagagggtt caggctcact actgctgaat
     5881 aagcctagcc gggccagtgt ctctgtcctt atgtctctgg aaatactata ttgactagat
     5941 taaaattgtg ctcttaaatc aaatttgggt attatatttt aatatgtaat ttgttaataa
     6001 gtaaccacag agtactgtct ggagtattaa gcttacagtt tattctccag ttttcagtct
     6061 cagctagaaa ctgtccttta gtcactatga atattggttt ccaatttggt ttggctgaaa
     6121 tttgctgctg acatgtcgag tttgtcctct taaagctgtc tttgtctctg ttcgctccgc
     6181 ctgtgttaga cagacctagc gagtgagtgt gctgatgaaa acgcatctct ctcagagctg
     6241 actctagaag gtgaggttgt cgatcttcct aaactgtgaa tgtgagtatg cccagcggca
     6301 tccatgtcat tttagtagta tttaaataaa ctccatgttt cttttgggcc taacatgcct
     6361 tttgaagtct gtataaactt gttttcaaat ctaatctgtt catatgaata taataaaaat
     6421 accttttgca tgataaaaat tactttgatt acaaaagaca tatatgcttt ttgtgaccag
     6481 caataaggaa ctgtaatgac tgatatttct attaaatgca cttaactata
//
