LOCUS       NM_001039646            3528 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus guanylate-binding protein 10 (Gbp10), mRNA.
ACCESSION   NM_001039646 XM_001005367 XM_987524 XM_987560 XM_987589 XM_987614
            XM_987647 XM_987685 XM_987723 XM_987759 XM_987793 XM_987820
VERSION     NM_001039646.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3528)
  AUTHORS   Kim BH, Shenoy AR, Kumar P, Das R, Tiwari S and MacMicking JD.
  TITLE     A family of IFN-gamma-inducible 65-kD GTPases protects against
            bacterial infection
  JOURNAL   Science 332 (6030), 717-721 (2011)
   PUBMED   21551061
  REMARK    GeneRIF: findings show that at least 4 IFN-gamma-inducible
            Gbps--Gbp1, Gbp6, Gbp7, and Gbp10--conferred cell-autonomous
            immunity to listerial or mycobacterial infection within macrophages
            and gene-deficient animals
REFERENCE   2  (bases 1 to 3528)
  AUTHORS   Degrandi D, Konermann C, Beuter-Gunia C, Kresse A, Wurthner J,
            Kurig S, Beer S and Pfeffer K.
  TITLE     Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10
            involved in host defense
  JOURNAL   J Immunol 179 (11), 7729-7740 (2007)
   PUBMED   18025219
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DQ985743.1.
            
            On or before Oct 30, 2006 this sequence version replaced
            XM_987793.1, XM_987759.1, XM_987820.1, XM_987647.1, XM_987560.1,
            XM_987685.1, XM_987723.1, XM_987524.1, XM_987589.1, XM_987614.1,
            XM_001005367.1, NM_001039646.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ985743.1, BC114209.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3528
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 50.68 cM"
     gene            1..3528
                     /gene="Gbp10"
                     /note="guanylate-binding protein 10"
                     /db_xref="GeneID:626578"
                     /db_xref="MGI:MGI:4359647"
     exon            1..62
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            63..270
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1922
                     /gene="Gbp10"
                     /codon_start=1
                     /product="guanylate-binding protein 10"
                     /protein_id="NP_001034735.2"
                     /db_xref="CCDS:CCDS51581.1"
                     /db_xref="GeneID:626578"
                     /db_xref="MGI:MGI:4359647"
                     /translation="MTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGW
                     SRTGKSYLMNCLAGQNHGFPLGSTVQSQTKGIWMWCMPHPTKPEHTLVLLDTEGLGDV
                     EKGDPKNDLWIFALSVLLSSTFIYNSMITINHQALEQLHYVTELTELIRAKSSPNPAG
                     IKNSTEFVSFFPDFVWIVRDFMLELKLNGEDITSDDYLENALKLIPGDKPRMQASNSC
                     RECIRLFFPNRKCFVFDRPTHDKELLQKLDSITEDQLDPKFQEVTKAFVSYIFTYAKI
                     KTLKEGIKVTGNKLGILVTTYVDAINSGAVPCLDDAVTTLAQRENSVAVQKAADHYSE
                     QMAQRLRLPTETLQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELIGENKELF
                     LSKNEEASNKYCQEELDRLSKDFMENISTFFVPCGHKLYMDKREKIEHDYWQVPRKGV
                     KASEVFQSFLQSQAFIESSILQADTALTAGKKAIAEERAQKVAAEKEQDLLRQKQKEQ
                     QEYMEAQEKSHKENIEQLRRKLMQEREQLIKDHNMMLKKQLKDQKAFLEEGFKKKAEE
                     MNKEIQQLRDVIKDKKRNTDRIKDALLNGFSTVLFHYLVRYLKHL"
     exon            271..398
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            399..508
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            509..705
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            706..951
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1232
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1439
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1542
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1736
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
     exon            1737..3528
                     /gene="Gbp10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtgattcct aggagagaga agcagctgaa aactgcactt ggacctgtac tgtggggacc
       61 agattcatct acgttggcag gttgctatga cccaaccaca aatggctccc atttgccttg
      121 tggaaaacca caatgaacag ctgtcagtga accaggaagc catagagatt ctggacaaga
      181 tttctcagcc agtggtagtc gtggctattg ttggatggtc ccgtactggg aagtcctatt
      241 tgatgaactg tctggcggga cagaatcacg gcttccctct gggctccact gtgcagtctc
      301 aaaccaaggg catctggatg tggtgcatgc cacaccccac caagccagag cacaccctgg
      361 tcctcctgga caccgagggc ctgggggatg tggaaaaggg tgatcctaag aacgacttgt
      421 ggatctttgc cctcagtgtg cttctgagca gcaccttcat ctacaacagc atgatcacca
      481 tcaaccacca ggccctggag cagctgcatt atgtcacaga actcacagag ctgatcagag
      541 caaagtcttc cccaaatcct gctggaataa agaattccac agagtttgtg agtttctttc
      601 cagactttgt ctggattgtt cgggatttca tgctggagct gaagttaaat ggggaagaca
      661 tcacaagtga tgactacctg gagaatgcct tgaagctgat cccaggtgac aaacccagaa
      721 tgcaagcatc caattcatgc agggaatgca tcagactttt ctttcctaac cggaagtgtt
      781 ttgtctttga ccggccaacg catgacaaag aacttttaca aaaacttgat tctatcacag
      841 aagaccaact ggatcctaag ttccaggaag taacaaaggc ttttgtttct tacatcttca
      901 cttatgccaa gatcaagacc ctaaaagagg gaattaaggt cactgggaat aaactaggga
      961 ttctggtgac aacctatgtg gatgccatca acagtggagc agtgccttgt ctggatgatg
     1021 ctgtgacaac tctggcccag cgtgagaact cagtagctgt gcagaaagca gccgaccact
     1081 atagtgagca gatggcccag cgactgaggc ttcctacaga aacgctccag gagctgctgg
     1141 atgtgcatgc agcctgcgag aaggaagcca tggctgtctt catggagcat tccttcaagg
     1201 acgaaaatca gcaattcctg aagaagctgg tggaattaat aggagagaac aaagagcttt
     1261 tcctgtcgaa gaatgaagag gcatcaaata aatactgtca agaagaactg gatcgacttt
     1321 caaaggattt tatggaaaat atttcaacat tttttgttcc ttgtggacac aagctttaca
     1381 tggacaagag ggagaagatt gagcatgact actggcaggt tcccaggaaa ggggtgaagg
     1441 caagtgaagt cttccagagc tttctgcagt cacaggcctt catcgagagt tccatcttgc
     1501 aggcagatac agcgctcact gctgggaaga aggccattgc agaggagcgt gcccagaagg
     1561 tggcggcaga gaaggagcag gatctgctaa gacagaagca gaaggagcag caggagtata
     1621 tggaggctca agagaaaagt cacaaggaaa acatagagca actgaggaga aagctgatgc
     1681 aggagagaga gcagctcatc aaagaccata acatgatgct gaagaagcag ctgaaggatc
     1741 aaaaggcttt ccttgaggaa ggatttaaga agaaagctga ggaaatgaac aaagagatac
     1801 agcaactgag agatgtcatc aaggataaga aaagaaacac tgatcgaatt aaggatgctc
     1861 tcttaaatgg attttctaca gttctttttc attaccttgt ccgttatcta aagcatttat
     1921 gattgagtcc ttcacatttg tggaaatgat agactgtgaa atacactttg tttcatacat
     1981 gcctgcaaag acaatgttag cctttagagg acacattttt gaaatgagcc ctatggaagc
     2041 tatgcaagta gtaattacat gtgattactg ttggccaatt tgactgcata gagaatcagc
     2101 aaggagacaa ggttttctgt actcctatga ggaccatgta gcccaggtta gcttgtgggg
     2161 gactgtctca ggttaatatt gtaggaaaca catcctacgg gtaggcagca ctgttcctgt
     2221 ggactgaaga aacagagaaa gatgaaaaca aatgacccta ccacttgtgg cttcctgact
     2281 gtggatgcta tacaacaagc caggctcaac ttctctcaga atgcattctc cagccttgac
     2341 acaatgtatc atcatgattc atagacccca acaaaccctt tcttaagttg gttttgtgag
     2401 ggtatttcat ctcagcaaga ggaaaagtca ttgatatcat aatcgtgata atcctggaaa
     2461 ctacttaaac atcacttgtt agattggcaa tgaaatttaa tatgacttga tcttggcgta
     2521 ctatatagtc aagaaacaaa tgtcagtcaa gctatctgta aaatgatctg aattgtacta
     2581 aaatgtaccc aaaagataaa gtcaaaacac catacaactg tgtgattatt attagaaatg
     2641 ctactatccc atgcaaacat acaagaacac aaatgaaatg ccctctggaa gattagtaaa
     2701 aagcctggtc tactggcttc atctagagag attaagttgg agccaaaagt tgaagggatg
     2761 tgtgcattcc atgacgttct cagtcttaca catttcatga agagtgctgg gaaagtgaca
     2821 gtgatagtga caataagtta aaactcacca ctgcatgatg aaacatctgc ttctagaaat
     2881 ggtataagcc actagaagtc acccaagaac aagacttgag taccaggaag cataacattt
     2941 gcagcttaat gatgttttcc tttaaggctt tccattttta aaagtaattt aaatagtgca
     3001 tttttttgta aaaccacata tcaaaatgtt atttcaacag gcaatcaaaa taatttatgc
     3061 atgcttttta catcaaattt atttatttgc aaagtaacag ggaaactgta ttaagagcca
     3121 tatgataata tagaatataa gagaatacat ggggcacatg ggaggtggag agctcagaga
     3181 tggctctggg tcaagaatgc acaatgctta tccagggtag ctcagttcct ggggcaggta
     3241 acaactacct gtaaatctaa ctccaaggga cctgacttcc ttttctcaaa cccaagggtc
     3301 actgttactt ccatcacata tcctcagctt acacatatac atacttacaa gtaagattta
     3361 aaggaatata ctgttaacat tgataatgga ccatatgagt aaagacacaa ggacacttat
     3421 tagtgcatta atgaatatga tttatttaag gtgtacccac cccagctcct ctaagacatc
     3481 ctcaaattac cctcgcacct tcatgtcttc tcttccccca cctcttcc
//
