LOCUS       NM_138601               1367 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus glutamine amidotransferase like class 1 domain
            containing 3A (Gatd3a), transcript variant 1, mRNA; nuclear gene
            for mitochondrial product.
ACCESSION   NM_138601
VERSION     NM_138601.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1367)
  AUTHORS   Kretschmer,V., Schneider,S., Matthiessen,P.A., Reichert,D.,
            Hotaling,N., Glassser,G., Lieberwirth,I., Bharti,K., De Cegli,R.,
            Conte,I., Nandrot,E.F. and May-Simera,H.L.
  TITLE     Deletion of IFT20 exclusively in the RPE ablates primary cilia and
            leads to retinal degeneration
  JOURNAL   PLoS Biol 21 (12), e3002402 (2023)
   PUBMED   38048369
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1367)
  AUTHORS   Patnaik,S.R., Kretschmer,V., Brucker,L., Schneider,S., Volz,A.K.,
            Oancea-Castillo,L.D.R. and May-Simera,H.L.
  TITLE     Bardet-Biedl Syndrome proteins regulate cilia disassembly during
            tissue maturation
  JOURNAL   Cell Mol Life Sci 76 (4), 757-775 (2019)
   PUBMED   30446775
REFERENCE   3  (bases 1 to 1367)
  AUTHORS   Manning,J.A., Colussi,P.A., Koblar,S.A. and Kumar,S.
  TITLE     Nedd1 expression as a marker of dynamic centrosomal localization
            during mouse embryonic development
  JOURNAL   Histochem Cell Biol 129 (6), 751-764 (2008)
   PUBMED   18239929
REFERENCE   4  (bases 1 to 1367)
  AUTHORS   Gitton,Y., Dahmane,N., Baik,S., Ruiz i Altaba,A., Neidhardt,L.,
            Scholze,M., Herrmann,B.G., Kahlem,P., Benkahla,A., Schrinner,S.,
            Yildirimman,R., Herwig,R., Lehrach,H. and Yaspo,M.L.
  CONSRTM   HSA21 expression map initiative
  TITLE     A gene expression map of human chromosome 21 orthologues in the
            mouse
  JOURNAL   Nature 420 (6915), 586-590 (2002)
   PUBMED   12466855
REFERENCE   5  (bases 1 to 1367)
  AUTHORS   Wiltshire,T., Pletcher,M., Cole,S.E., Villanueva,M., Birren,B.,
            Lehoczky,J., Dewar,K. and Reeves,R.H.
  TITLE     Perfect conserved linkage across the entire mouse chromosome 10
            region homologous to human chromosome 21
  JOURNAL   Genome Res 9 (12), 1214-1222 (1999)
   PUBMED   10613844
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK003866.1 and AI852165.1.
            
            On Jun 26, 2018 this sequence version replaced NM_138601.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK003866.1, BC013475.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1350              AK003866.1         15-1364
            1351-1367           AI852165.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1367
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..1367
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /note="glutamine amidotransferase like class 1 domain
                     containing 3A"
                     /db_xref="GeneID:28295"
                     /db_xref="MGI:MGI:1351861"
     exon            1..161
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..827
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; ES1 protein homolog, mitochondrial; glutamine
                     amidotransferase-like class 1 domain-containing protein
                     3A, mitochondrial; glutamine amidotransferase-like class 1
                     domain-containing protein 3, mitochondrial"
                     /codon_start=1
                     /product="glutamine amidotransferase-like class 1
                     domain-containing protein 3, mitochondrial isoform 1
                     precursor"
                     /protein_id="NP_613067.1"
                     /db_xref="CCDS:CCDS35957.1"
                     /db_xref="GeneID:28295"
                     /db_xref="MGI:MGI:1351861"
                     /translation="MAAVRVLVAPRLASALLPLSRYHRAPSQRAALHSSAPRPGARVA
                     LVLSGCGVYDGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHVIDHTKGEPSERESRN
                     VLAESARIARGKITSLAQLNAANHDAAIFPGGFGAAKNLSTFAVDGKDCKVNKEVERV
                     LKEFHGAKKPIGLCCIAPVLAAKVIKGVEVTVGHEQEEGGKWPYAGTAEAIKALGAKH
                     CVKGVTEAHVDQKNKVVTTPAFMCETALHHIHDGIGAMVKNVLELTGK"
     exon            162..214
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /inference="alignment:Splign:2.1.0"
     exon            215..328
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /inference="alignment:Splign:2.1.0"
     exon            329..448
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /inference="alignment:Splign:2.1.0"
     exon            449..541
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /inference="alignment:Splign:2.1.0"
     exon            542..698
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /inference="alignment:Splign:2.1.0"
     exon            699..1351
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1318..1323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /note="hexamer: AATAAA"
     polyA_site      1351
                     /gene="Gatd3a"
                     /gene_synonym="C21orf33; D10Jhu81e; ES1; Gatd3"
                     /note="major polyA site"
ORIGIN      
        1 accactgtgg ctggctgccc ttcgtgatgg ctgccgtcag ggttttggtg gcgccaaggc
       61 tggcttctgc gctcctaccg ctctccagat accaccgggc tccctcccag cgcgcagccc
      121 ttcacagctc cgcaccgcgg cccggggcca gggtggcgtt ggtgctgtcg ggctgtggag
      181 tctatgacgg aaccgagatc catgaggcct cagcgatcct ggtgcacctg agccgaggcg
      241 gggctgaggt ccagatcttt gctcccgatg tccctcagat gcacgtgatt gaccacacca
      301 agggggagcc ttctgagagg gaaagcagga acgttttggc agagtcagca aggattgccc
      361 gaggcaagat taccagcctg gctcagctca atgctgctaa ccatgatgct gccattttcc
      421 caggaggctt tggagctgcc aaaaacctga gcacattcgc cgtggacgga aaggactgca
      481 aggttaacaa ggaggtagag cgggtcctga aggagttcca cggggccaag aagcccattg
      541 gcttatgctg catcgctcct gtcctcgcag ccaaagtgat caaaggtgtg gaggtcaccg
      601 taggccatga gcaagaggag ggcggcaagt ggccttatgc tggaactgcg gaagccatca
      661 aagccctggg tgccaagcac tgtgtgaagg gtgtgaccga agctcatgta gaccagaaaa
      721 acaaggtggt caccacccca gccttcatgt gtgagaccgc actccaccac atccacgacg
      781 ggatcggggc catggtaaag aatgtgctgg aactcacggg aaagtaatgc cacccggacc
      841 acgcttggcc tccgtgactg tggcatcccc agccggcgtg tgctccatgg cttcagcccg
      901 gacacaggag ccgcttagct actaggagca tagacacttc ctgcctgaag gaggagctta
      961 gcctctgtat gtccagcctg agcttctacc agcaggaagc tcagggaccc tccctgggcc
     1021 ctgagcagca gcaggagctt catggggtgg ggagggaggg agcgggcttg cctcactgcg
     1081 tgtccccatg gaagatctaa gcacctttcc cagagcctgg ttgaaggact taggttctcc
     1141 gatcctgggt ctgataggtc agggtactaa agctttaaaa gaagaaacca gtttaggttc
     1201 taagtcgtct gataaccaga ggtgcctagt ttgtggataa agaaaagctc tctgatccag
     1261 agtaaagaca gctaactaaa gccacgggga ttctgtagta ggtccctgta gccacagaat
     1321 aaactcttcc gcacgatgga aactcctttc aaaaaaaaaa aaaaaaa
//
