LOCUS       NM_144896               3485 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus glutamyl-tRNA amidotransferase subunit B (Gatb),
            transcript variant 1, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_144896
VERSION     NM_144896.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3485)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3485)
  AUTHORS   Echevarria,L., Clemente,P., Hernandez-Sierra,R., Gallardo,M.E.,
            Fernandez-Moreno,M.A. and Garesse,R.
  TITLE     Glutamyl-tRNAGln amidotransferase is essential for mammalian
            mitochondrial translation in vivo
  JOURNAL   Biochem J 460 (1), 91-101 (2014)
   PUBMED   24579914
REFERENCE   3  (bases 1 to 3485)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102296.6 and AC102338.10.
            
            On Jan 5, 2022 this sequence version replaced NM_144896.4.
            
            Sequence Note: T.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034702.1, BC005709.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-201               AC102296.6         111151-111351
            202-352             AC102296.6         112896-113046
            353-466             AC102296.6         138892-139005
            467-665             AC102296.6         141413-141611
            666-788             AC102296.6         142047-142169
            789-902             AC102296.6         148384-148497
            903-987             AC102296.6         150495-150579
            988-1032            AC102296.6         153647-153691
            1033-1222           AC102296.6         155856-156045
            1223-1356           AC102296.6         173956-174089
            1357-1435           AC102296.6         182002-182080
            1436-1570           AC102338.10        13541-13675
            1571-3485           AC102338.10        14984-16898
FEATURES             Location/Qualifiers
     source          1..3485
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 37.83 cM"
     gene            1..3485
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /note="glutamyl-tRNA amidotransferase subunit B"
                     /db_xref="GeneID:229487"
                     /db_xref="MGI:MGI:2442496"
     exon            1..201
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            202..352
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            353..466
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            467..665
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            666..788
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            789..902
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            903..987
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1032
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1222
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1356
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1435
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1570
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..3485
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1988..1993
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /note="hexamer: AATAAA"
     polyA_site      2011
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /note="major polyA site"
     regulatory      2273..2278
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /note="hexamer: AATAAA"
     regulatory      2278..2283
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /note="hexamer: AATATA"
     polyA_site      2296
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
     regulatory      2297..2302
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /note="hexamer: CATAAA"
     polyA_site      2304
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
     polyA_site      2319
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
     regulatory      3452..3457
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
                     /note="hexamer: AATATA"
     polyA_site      3485
                     /gene="Gatb"
                     /gene_synonym="9430026F02Rik; Pet112; Pet112l"
ORIGIN      
        1 acctgaccgg gacttcggcg acgctatggc ggcgcccatg ctgcgcttgg gtttccctgg
       61 aagacgctgg gctttaacat ggctagatgg cggttcccgc caccgaagtg gctctcagac
      121 tgggcccaca tccaactggg ctaggagaca gagttcagtg gctcagcctt ccctccacac
      181 ggctcagaag ccgaggaaag gtgaacacaa atgggcagct gtagtaggac tggaaattca
      241 tgcacagatt tcctccaact ctaaactctt ctctggagct caagtgtgct ttgcagcacc
      301 tccaaattct ctggtttctt attttgatgc atctctgcct ggaacattac cggttctcaa
      361 caggaggtgt gtggaagccg cggtgatgac tggcttggca ctgaactgcc acataaacaa
      421 gaagtccttg tttgaccgga agcactactt ctactcagac cttcctgctg gctaccagat
      481 cacccagcag aggctcccaa ttgctgccaa tggacacttg acctactgta tctatctagg
      541 gaagaaaccc agtcaggtga ccaccaagac agtgaggatc aagcagatcc agttggagca
      601 ggacagtggc aaaagcctcc atgacgacct gaggtcacag acactcattg atttgaacag
      661 agccggaatt ggccttcttg aagtggtcct ggagcctgac ctgtgctgtg gagaagaggc
      721 agccctagct gtcagggaac tgcagctgat ccttcaagcc ctgggcacca gccaagccaa
      781 catggcagag ggtcagctga gagtggatgc caatatatct gtacatcacc ctggggaacc
      841 actgggtgtc aggactgagg taaagaatct caacagcctc aggttcttgg ccaaagccat
      901 agattatgaa attcagaggc aaatcactga acttgagaat ggaggtgaaa ttctgaatga
      961 aactcgttca tttgattata agctggggtg caccatgcca atgagagaca aggaagggaa
     1021 acaagactac aggtttatgc cagagcccaa cctgcctccc ttagtgctct acgatgacac
     1081 atctctgcca cgaggtgcag actctcagca ggtgatcaat attgaccagc ttcgggacat
     1141 gctcccggag ctccccagtg caaccagaga aaggctggtc cagcagtatg ggatgcttcc
     1201 cgagcacagc tttgcgttac tgaatgaagt tggcctactg gagttcttcc agaatgtgat
     1261 aaaagaaact aggacagagc caaaaaaggt gactaactgg gtcctgaaca cttttctgtg
     1321 ctatttaaag caacagaatc ttgcagtcag tgagagtcct gtcacaccct ctgcacttgc
     1381 tgagctcctc aacctgctgg acaggaaagc aatttcttca tcggcagcta agcaggtgtt
     1441 tgaggagctg tggaaggggg aggggaagac agcagcacag atcgtgtcag aacagcagct
     1501 ggagctgatg caggatcaag aggccctgga aaagctctgc cagaccacca tagatggaca
     1561 cccccaagtg gtgatggatg tgaagaaaag aaaccccaaa gctataaata agctgattgg
     1621 gttggtgcgg aaggcaagcc acagcagggc agacccggct ctgataaaga aaatattgga
     1681 gaggaagctg tcattgtgag atgtgtgggg tccctctgcc ggatggagga cagtgtggct
     1741 ctgagaagag gggcctgtga gggctggaac tcatgtgctg tacaagttgt atctcttagt
     1801 ccctagccaa gctacacttc ctaggaggcc aggaggcaat agtttacacc tgtgtgtgtc
     1861 ctatgagacc ccatgacctg agaggcagcc atcacggaag accagcagcc agagtgtcag
     1921 cctcactgtc tggaaatggc cccatgatgg tggcagcagt gactaaagaa attgtaagtc
     1981 tacacagaat aaagttcacg tccccacctc agatgccgtg ggtgctttgt agagccaagc
     2041 agtgctcccc atcctaaagg ccgacagacc aagaacacgg cagcatgagt ggagtgtggt
     2101 gtgttcagac ctaaacacgg gctggtgaag atgtaaacag aagaacttaa cttggtgttc
     2161 aggcaaggga gggcaggagg gtgctggcac tcacctgctg agtggaggca ctgtcgcctg
     2221 ctcggctccc agtgaattaa ggtgacacac aagttctcag ataaatttaa tgaataaaat
     2281 atatactgaa atagcacata aaaattaact tccacgtaag agattgtata gtttacatcc
     2341 ttcccacaca caatgcttag gcagagagag ggagggaggg agggagagag aggaaagaga
     2401 gagagagagg gagagggaga gagagagaga gagagagtgt tttacctgga aagaataaga
     2461 tcatgctgtt atacatcaga atgctcacct ttagctctct tgtggtacag ctgctacatc
     2521 ctcagtccta ggtggtgtgt ccccttgttt cttacatgtc tggtacctca caccaacctc
     2581 actctttatg actagttctg agaatgtttt ttagaagtgt ttgtcaaact gacagagaag
     2641 gggaactctc ggaggccctc atcttagacc agactctcag gcctggtaag aacattgctg
     2701 ggcaccatca ttccagggca actgaagaat gagaagaaag tggacacacc cgtcaccaga
     2761 agatggcacc cagcgttgct aagcaacttc acccagccaa aagctgaggc tgtgtggaca
     2821 tcagttctat ggtctgtttc agacaagcag gaggaggtaa ctttaggatg tcatctctct
     2881 caggaagcca cagaccatgt gttgccctga tgaaacaggc tgttcaagtg tttgattagc
     2941 ctccctacag gagagaaagg cgggacctgc tgctctacaa gcctgaactc cagtggccag
     3001 aggtgctcag atcctaatct gaccagacct ttatctcaaa gaacagtaag gttcagtctt
     3061 ataacctcca tttttaccaa aaagaaaatg gttcatctgg cttggtcatc aagccttgca
     3121 gaaagcactt acaaagctaa caccctgggc tacctcagtg ggtggtgaaa tgggcagctc
     3181 agtggaagcc atttccaaaa cctactttat cagttggaaa acacacatgg actgagtatt
     3241 cccagaggag acgccatcag cacgcagtcc ttgcgaggct ccttcctccc agctagctct
     3301 gacagctgcc tcattctctt ggtcatcttg aaaccctaag gcaagctttg agctcataac
     3361 cacagctact agggaaatag ccaaacccat gaactgcatg actagataca tttgaaagat
     3421 gtgtttatat aacattttaa aagatgcata aaatatagct ctgctggtgc atgggtgcag
     3481 tgaaa
//
