LOCUS       NM_010258               3194 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus GATA binding protein 6 (Gata6), mRNA.
ACCESSION   NM_010258
VERSION     NM_010258.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3194)
  AUTHORS   Jasmine, Baraiya,D.H., Kavya,T.T., Mandal,A., Chakraborty,S.,
            Sathish,N., Francis,C.M.R. and Binoy Joseph,D.
  TITLE     Epithelial and mesenchymal compartments of the developing bladder
            and urethra display spatially distinct gene expression patterns
  JOURNAL   Dev Biol 520, 155-170 (2025)
   PUBMED   39798644
REFERENCE   2  (bases 1 to 3194)
  AUTHORS   Hirono,N., Hashimoto,M., Shimojo,H. and Sasaki,H.
  TITLE     Fate specification triggers a positive feedback loop of TEAD-YAP
            and NANOG to promote epiblast formation in preimplantation embryos
  JOURNAL   Development 152 (1) (2025)
   PUBMED   39629521
REFERENCE   3  (bases 1 to 3194)
  AUTHORS   Weberling,A., Siriwardena,D., Penfold,C., Christodoulou,N.,
            Boroviak,T.E. and Zernicka-Goetz,M.
  TITLE     Primitive to visceral endoderm maturation is essential for mouse
            epiblast survival beyond implantation
  JOURNAL   iScience 28 (1), 111671 (2024)
   PUBMED   39868030
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3194)
  AUTHORS   Wang,Y., Zhang,Y., Kim,K., Han,J., Okin,D., Jiang,Z., Yang,L.,
            Subramaniam,A., Means,T.K., Nestle,F.O., Fitzgerald,K.A.,
            Randolph,G.J., Lesser,C.F., Kagan,J.C., Mathis,D. and Benoist,C.
  TITLE     A pan-family screen of nuclear receptors in immunocytes reveals
            ligand-dependent inflammasome control
  JOURNAL   Immunity 57 (12), 2737-2754 (2024)
   PUBMED   39571575
REFERENCE   5  (bases 1 to 3194)
  AUTHORS   Fan,W., Li,Z., He,X., Wang,X., Sun,M. and Yang,Z.
  TITLE     SLC25A1 regulates placental development to ensure embryonic heart
            morphogenesis
  JOURNAL   Development 151 (22) (2024)
   PUBMED   39591637
REFERENCE   6  (bases 1 to 3194)
  AUTHORS   Kuo,C.T., Morrisey,E.E., Anandappa,R., Sigrist,K., Lu,M.M.,
            Parmacek,M.S., Soudais,C. and Leiden,J.M.
  TITLE     GATA4 transcription factor is required for ventral morphogenesis
            and heart tube formation
  JOURNAL   Genes Dev 11 (8), 1048-1060 (1997)
   PUBMED   9136932
REFERENCE   7  (bases 1 to 3194)
  AUTHORS   Morrisey,E.E., Ip,H.S., Tang,Z., Lu,M.M. and Parmacek,M.S.
  TITLE     GATA-5: a transcriptional activator expressed in a novel temporally
            and spatially-restricted pattern during embryonic development
  JOURNAL   Dev Biol 183 (1), 21-36 (1997)
   PUBMED   9119112
REFERENCE   8  (bases 1 to 3194)
  AUTHORS   Narita,N., Heikinheimo,M., Bielinska,M., White,R.A. and Wilson,D.B.
  TITLE     The gene for transcription factor GATA-6 resides on mouse
            chromosome 18 and is expressed in myocardium and vascular smooth
            muscle
  JOURNAL   Genomics 36 (2), 345-348 (1996)
   PUBMED   8812463
REFERENCE   9  (bases 1 to 3194)
  AUTHORS   Qureshi,S.T., Bronchain,O., Nemer,M. and Malo,D.
  TITLE     Mapping of the Gata6 gene to mouse chromosome 18
  JOURNAL   Mamm Genome 7 (9), 705-706 (1996)
   PUBMED   8703130
REFERENCE   10 (bases 1 to 3194)
  AUTHORS   Morrisey,E.E., Ip,H.S., Lu,M.M. and Parmacek,M.S.
  TITLE     GATA-6: a zinc finger transcription factor that is expressed in
            multiple cell lineages derived from lateral mesoderm
  JOURNAL   Dev Biol 177 (1), 309-322 (1996)
   PUBMED   8660897
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY084328.1, AK142381.1, AI120546.1 and BB042635.1.
            
            On May 12, 2006 this sequence version replaced NM_010258.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK142381.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-141               BY084328.1         41-181
            142-2783            AK142381.1         2-2643
            2784-3189           AI120546.1         25-430              c
            3190-3194           BB042635.1         298-302
FEATURES             Location/Qualifiers
     source          1..3194
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 5.63 cM"
     gene            1..3194
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /note="GATA binding protein 6"
                     /db_xref="GeneID:14465"
                     /db_xref="MGI:MGI:107516"
     exon            1..234
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /inference="alignment:Splign:2.1.0"
     exon            235..1388
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /inference="alignment:Splign:2.1.0"
     CDS             272..2041
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /note="GATA-binding factor 6"
                     /codon_start=1
                     /product="transcription factor GATA-6"
                     /protein_id="NP_034388.2"
                     /db_xref="CCDS:CCDS29059.1"
                     /db_xref="GeneID:14465"
                     /db_xref="MGI:MGI:107516"
                     /translation="MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSS
                     SCSRGGDRGPCGASNCRTPQLDAEAVAGPPGRSLLLSPYASHPFAAAHGAAAPGVAGP
                     GSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSSQGPA
                     AYDGAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLSGLPYLQGAGSGPSNHAGGA
                     GAHPGWSQASADSPPYGGGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARD
                     PGGYVAAGGTGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGTYHHHHHHHPTYSPY
                     MAAPLTPAWPAGPFETPVLHSLQGRAGAPLPVPRGPSTDLLEDLSESRECVNCGSIQT
                     PLWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSSRRLGLSCANCHTTTTTLWR
                     RNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSSGSVPM
                     TPTSSSSNSDDCTKNTSPSTQATTSGVGASVMSAVGENANPENSDLKYSGQDGLYIGV
                     SLSSPAEVTSSVRQDSWCALALA"
     exon            1389..1555
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1681
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1769
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1873
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..3194
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3160..3165
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /note="hexamer: AATAAA"
     polyA_site      3189
                     /gene="Gata6"
                     /gene_synonym="GATA-6"
                     /note="major polyA site"
ORIGIN      
        1 cccacagcct ggcacccttc ggctagcgct gtttgtttag ggctcggtga gtccaatcag
       61 gagcgcaggc tgcagttttc cggcagagca gtaagaggcg cctcctctct cctttttatt
      121 caccagcagc gactagcaga ccccggactc tcgctctccc gccggcgccc tccgcctctc
      181 tccgcgcccc ggagcaccct cggtcgcggc cgttcttctc gcacatcgct cgaggaatca
      241 aaagtcaggt tggagtagcg ccggacagtg gatggccttg actgacggcg gctggtgcct
      301 gccaaagcgt ttcggggctg ctgctgcgga cgccggcgac tccgggccct ttccagcgcg
      361 ggagccctcc tcgccgcttt cccccatctc gtcttcgtcc tcctcctgct cccggggcgg
      421 ggatcgcggt ccctgcggcg ccagcaactg caggacgccg cagctcgacg ccgaggcggt
      481 ggcgggacct ccgggccgct cgctcttgct cagcccctac gcctcgcatc ccttcgccgc
      541 tgcccacgga gccgcggcgc ccggggtcgc aggccccggg agcgccctgt cgacttggga
      601 ggacctgttg ctcttcactg acctcgatca ggccgcgacc gccagcaagc tgttgtggtc
      661 cagccggggc gccaaactga gccccttcgc ggccgagcag ccggaggaaa tgtaccagac
      721 cctcgccgcc ctgtccagcc aggggcccgc cgcttacgac ggcgcgcccg gcggcttcgt
      781 gcactccgca gcggcggcgg ccgctgccgc cgcggcagcc agctccccgg tctacgtgcc
      841 caccacgcgc gtgggctcca tgctgtccgg cctgccctac cttcaagggg cgggcagcgg
      901 gcccagcaat cacgcgggcg gagcgggtgc ccacccaggc tggtcccagg cctccgccga
      961 cagccccccg tatggcgggg gtggcgcagc cggcggcggc gcggccggac ctggaggtgc
     1021 gggatcggct acggcccacg cctctgcacg ctttccctac tcgcccagcc cgcccatggc
     1081 caacggcgcc gcgcgagacc ccgggggcta cgtggctgcg ggcggcacgg gcgcaggcag
     1141 tgtgagtgga ggtggcggca gcctggcggc catgggtggc cgggagcacc agtacagctc
     1201 gctgtccgca gctcggccgc tgaacggaac gtaccaccac caccatcacc atcacccgac
     1261 ctactcgccc tacatggccg caccgctgac tcctgcctgg ccagcaggac ccttcgaaac
     1321 gccggtgctc cacagcttac agggccgcgc gggagctcca ctcccggtgc cacggggccc
     1381 cagcacagac ctgttggagg acctgtcgga gagccgcgag tgcgtgaact gcggctccat
     1441 ccagacgcca ctgtggagac gagacggcac cggtcattac ctgtgcaatg catgcggtct
     1501 ctacagcaag atgaatggcc tcagcaggcc cctcatcaag ccacagaagc gcgtgccttc
     1561 atcacggcgg cttggactgt cctgtgccaa ctgtcacacc acaaccacta ccttatggcg
     1621 tagaaatgct gagggtgagc ctgtgtgcaa tgcttgcggg ctctatatga aactccatgg
     1681 ggtgcctcga ccacttgcta tgaaaaaaga aggaattcaa accaggaaac gaaaacctaa
     1741 aaatataaat aagtcaaaag cttgctccgg taacagcagt ggctctgtcc ctatgactcc
     1801 tacttcctct tcttctaatt cagatgactg caccaaaaat acttctcctt ctacacaagc
     1861 gaccacctca ggggtagggg catcagtgat gtctgcagtg ggagaaaacg ccaaccccga
     1921 gaacagtgac ctcaagtatt caggtcaaga cggcctctac ataggtgtca gtctgtcctc
     1981 ccctgccgaa gtcacatcct ccgtgcgaca ggattcttgg tgtgctctgg ccctggcctg
     2041 agctggtgct accaagaggc aaggagggct ctgaaggcct cataccactt gtgtctgata
     2101 ttgtccagca gtccagatgg cagcaaaaat gcagacataa cattccttcg atgcgtgatt
     2161 tctgtgcctt tgttttgaaa gagatatatt tctcaagaag cttactgaag taagaagaga
     2221 tgggcttttg caggaagggc cagcaccgtg ggcatgtggc ctgctcctgc cagcctgggc
     2281 tgcttcctgc ctctgactct gccccatacc agtgggagaa actgtgacaa tgaccggggc
     2341 cttgtctgct aaggaagatt gagagattta agagaaaatg tttgtgtatt gctccaaatc
     2401 atgtgcttct tgtgatcaac ctcggttatc ccagaaccca ttcatccccg accaccgtgc
     2461 acatttcaca agcgttcgtg gagaggagca ctgggagcca tttggtctat cctggaggcg
     2521 gagtgcattc ctggggtctc aacaagaata ttaatttgca agattgcatc atgacagaca
     2581 ctgactgact tatctcaacg ttcatcgtaa cgtggctgat ctgaggtcac ttggaatttg
     2641 taaacagggt agcaaacaag atatttttct tccatgtaca caataatttt tttaagtgca
     2701 atttgcgttg cagcaatcag tgttaaatca tttgcataag atttaacagc atttttataa
     2761 tgaatgtaaa cattttaact taatggtact taaaataatt taaaaaaaag ttaactttag
     2821 acatatgctt cttacactca cagcccactt ctgtgttccc aattgtttaa aagaaaaaaa
     2881 aaaagatttc aagaacaaat cttctctcag gaaattgcct tttctccatt tatgaatttt
     2941 tatacaagaa caccaacaca gtccccgttc ttttactgag gaaaaagtgc tggaaattgc
     3001 aacaaacctt tactacctag agaatagcat ttgtaaatat tctaagtatc tgtaacactc
     3061 ttgacgcctg taccacgtga ccaacccaca ggttggttta cattattatt ttttttaatg
     3121 ggatatcata tggaaaccta tttcaccaga gttttaaaaa ataaaaaggg tattgttttg
     3181 tgttctgtac agtg
//
