LOCUS       NM_001410603            1979 bp    mRNA    linear   ROD 26-NOV-2024
DEFINITION  Mus musculus GATA binding protein 1 (Gata1), transcript variant 1,
            mRNA.
ACCESSION   NM_001410603
VERSION     NM_001410603.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Rao,Z., Liu,S., Li,Z., Wang,Q., Gao,F., Peng,H., Ren,D., Zang,Y.,
            Li,H., Li,Y., Hu,Q., He,D. and Xu,H.
  TITLE     Alarmin-loaded extracellular lipid droplets induce airway
            neutrophil infiltration during type 2 inflammation
  JOURNAL   Immunity 57 (11), 2514-2529 (2024)
   PUBMED   39366382
REFERENCE   2  (bases 1 to 1979)
  AUTHORS   Bessell,E., Finlay,R.E., James,L.K., Ludewig,B., Harris,N.L.,
            Krebs,P., Hepworth,M.R. and Dubey,L.K.
  TITLE     Stromal cell and B cell dialogue potentiates IL-33-enriched
            lymphoid niches to support eosinophil recruitment and function
            during type 2 immunity
  JOURNAL   Cell Rep 43 (8), 114620 (2024)
   PUBMED   39141517
REFERENCE   3  (bases 1 to 1979)
  AUTHORS   Huang,S., Reed,C., Ilsley,M., Magor,G., Tallack,M., Landsberg,M.,
            Mitchell,H., Gillinder,K. and Perkins,A.
  TITLE     Mutations in linker-2 of KLF1 impair expression of membrane
            transporters and cytoskeletal proteins causing hemolysis
  JOURNAL   Nat Commun 15 (1), 7019 (2024)
   PUBMED   39147774
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1979)
  AUTHORS   Kim,H.J., Jang,J., Na,K., Lee,E.H., Gu,H.J., Lim,Y.H., Joo,S.A.,
            Baek,S.E., Roh,J.Y., Maeng,H.J., Kim,Y.H., Lee,Y.J., Oh,B.C. and
            Jung,Y.
  TITLE     TLR7-dependent eosinophil degranulation links psoriatic skin
            inflammation to small intestinal inflammatory changes in mice
  JOURNAL   Exp Mol Med 56 (5), 1164-1177 (2024)
   PUBMED   38689088
REFERENCE   5  (bases 1 to 1979)
  AUTHORS   Cardarelli,S., Biglietto,M., Orsini,T., Fustaino,V., Monaco,L., de
            Oliveira do Rego,A.G., Liccardo,F., Masciarelli,S., Fazi,F.,
            Naro,F., De Angelis,L. and Pellegrini,M.
  TITLE     Modulation of cAMP/cGMP signaling as prevention of congenital heart
            defects in Pde2A deficient embryos: a matter of oxidative stress
  JOURNAL   Cell Death Dis 15 (2), 169 (2024)
   PUBMED   38395995
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1979)
  AUTHORS   Berry,M., Grosveld,F. and Dillon,N.
  TITLE     A single point mutation is the cause of the Greek form of
            hereditary persistence of fetal haemoglobin
  JOURNAL   Nature 358 (6386), 499-502 (1992)
   PUBMED   1379347
REFERENCE   7  (bases 1 to 1979)
  AUTHORS   Simon,M.C., Pevny,L., Wiles,M.V., Keller,G., Costantini,F. and
            Orkin,S.H.
  TITLE     Rescue of erythroid development in gene targeted GATA-1- mouse
            embryonic stem cells
  JOURNAL   Nat Genet 1 (2), 92-98 (1992)
   PUBMED   1302015
  REMARK    Review article
REFERENCE   8  (bases 1 to 1979)
  AUTHORS   Attaya,M., Jameson,S., Martinez,C.K., Hermel,E., Aldrich,C.,
            Forman,J., Lindahl,K.F., Bevan,M.J. and Monaco,J.J.
  TITLE     Ham-2 corrects the class I antigen-processing defect in RMA-S cells
  JOURNAL   Nature 355 (6361), 647-649 (1992)
   PUBMED   1538753
REFERENCE   9  (bases 1 to 1979)
  AUTHORS   Minie,M., Clark,D., Trainor,C., Evans,T., Reitman,M., Hannon,R.,
            Gould,H. and Felsenfeld,G.
  TITLE     Developmental regulation of globin gene expression
  JOURNAL   J Cell Sci Suppl 16, 15-20 (1992)
   PUBMED   1297648
  REMARK    Review article
REFERENCE   10 (bases 1 to 1979)
  AUTHORS   Zon,L.I., Gurish,M.F., Stevens,R.L., Mather,C., Reynolds,D.S.,
            Austen,K.F. and Orkin,S.H.
  TITLE     GATA-binding transcription factors in mast cells regulate the
            promoter of the mast cell carboxypeptidase A gene
  JOURNAL   J Biol Chem 266 (34), 22948-22953 (1991)
   PUBMED   1744088
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL670169.9.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422601.73919.1,
                                           SRR13422589.107292.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164140, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               AL670169.9         66034-66259         c
            227-465             AL670169.9         65078-65316         c
            466-843             AL670169.9         64246-64623         c
            844-989             AL670169.9         63999-64144         c
            990-1115            AL670169.9         62658-62783         c
            1116-1979           AL670169.9         61340-62203         c
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 3.59 cM"
     gene            1..1979
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /note="GATA binding protein 1"
                     /db_xref="GeneID:14460"
                     /db_xref="MGI:MGI:95661"
     exon            1..226
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            227..465
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            466..843
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            844..989
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1115
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1116..1979
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1957..1962
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /note="hexamer: AATAAA"
     polyA_site      1979
                     /gene="Gata1"
                     /gene_synonym="eryf1; Gata-1; Gf-1"
                     /note="major polyA site"
ORIGIN      
        1 agatggcaag atacaacaga tagggatgaa gttggggagc acagaagggt gaaccccaaa
       61 ctcctatggg agctgtcaag gggtccaagg gatcttggtc ctgcattctg cctctgcaga
      121 aggaaagaaa ggaaggggaa gagagaataa aaagaggaaa tggaggaggc cttgaagaat
      181 gggagaaaga gaagcaaagg cttgccggag gaggagaaag aggaaggttc aaccccagtg
      241 ttcccatgga ttttcctggt ctaggggccc tggggacctc agaacccttg ccccagtttg
      301 tggattctgc cctggtgtcc tcaccatcag attccacagg tttcttttcc tctgggccag
      361 agggtttgga tgcagcatct tcttccactt ccccaaatgc agccacggcc gcagcatcag
      421 cactggccta ctacagagaa gctgaggcct acagacactc cccagtcttt caggtgtatc
      481 cactgctcaa cagtatggag ggaattcctg ggggctcacc ttatgctagc tgggcctatg
      541 gcaagacggc actctaccct gcctcaactg tgtgccccag ccatgaggat gccccttccc
      601 aggccctgga agaccaggaa gggaagagca acaacacgtt cttggacacc ttgaagacgg
      661 agcggctgag tccagacctc ctgacgctgg ggactgcact gcctgcatcg ctccctgtca
      721 ccggcagtgc ttacggggga gctgactttc ccagtccttt cttctctccc actgggagcc
      781 ctctcagctc agcagcctat tcttccccca agtttcatgg aagcctgcca ttggcccctt
      841 gtgaggccag agagtgtgtg aactgtggag caacggctac tccactgtgg cggagggaca
      901 ggacaggtca ctacctgtgc aatgcctgtg gcttgtatca caagatgaat ggtcagaacc
      961 ggcctctcat ccggcccaag aagcgaatga ttgtcagcaa acgggcaggc acccaatgca
     1021 ctaactgtca aacgaccact acaacactct ggcggaggaa tgccagcgga gatccggtat
     1081 gcaatgcctg cggcctctat ttcaagctcc atcaggtgaa ccgcccactg accatgagga
     1141 aagatggaat ccagacgagg aaccgcaagg catctggcaa agggaaaaag aagcgggggt
     1201 cgaatctggc tggagcggga gcggctgaag gaccagctgg tggcttcatg gtggtagctg
     1261 gtagcagcag tagtgggaat tgtggggagg tggcctcagg cttggcactg ggcactgcag
     1321 gtactgccca cctctatcag ggcctaggac ctgtggtact gtcagggcct gtcagccatc
     1381 ttatgccttt tcctggacct ctgctgggat cgcctacaac ctccttcccc accggtcctg
     1441 cacctaccac cagcagcacc agcgtgatcg ccccactcag ttcttgaagg tacacagaat
     1501 agccttgacc ttgtggcaga ggagaccccc cctttttttg gagacaggat cttctgtagc
     1561 tatgtagcta tgaactatgt agataagggt gaccccacat ttcccattct cctgcctcta
     1621 cctcccgagt actgagattc aggcatgtat tgctatgcct gacattttcc ttcctttcag
     1681 ttttgttttg tggggtttgt tgttgttgtt ttgagacagg gtttcactat gcagcctagg
     1741 ctggctttga attccttatg tagtccagac taagctccag cttgagatcc ttgtgcctca
     1801 gttcctgagt gctgggatta caggcatgtg ctaccgtgcc cgtttctccc tcctcttaga
     1861 gccactggcc tttacagccc aaccatctcc ttgccctgca cccttaaaga ttttgtaaaa
     1921 taaaaccacc tggagacatg cgctggtatt tggttaaata aatgtcagtg tcaagtgga
//
