LOCUS       NM_001408675            3654 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus golgi associated kinase 1A (Gask1a), transcript
            variant 5, mRNA.
ACCESSION   NM_001408675 XM_006512130
VERSION     NM_001408675.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3654)
  AUTHORS   Wei,Z., Liu,T., Lei,J., Wu,Y., Wang,S. and Liao,K.
  TITLE     Fam198a, a member of secreted kinase, secrets through caveolae
            biogenesis pathway
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 50 (10), 968-975 (2018)
   PUBMED   30188967
  REMARK    GeneRIF: In mouse embryo fibroblasts (MEFs) obtained from
            cavin-1-/- or caveolin-1-/- mice, Fam198a precursor was retained in
            ER and no mature Fam198a could be formed in these cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164092.3.
            
            On Jun 21, 2022 this sequence version replaced XM_006512130.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK134876.1, SRR17784647.1221901.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-192               AC164092.3         87288-87479         c
            193-1440            AC164092.3         72552-73799         c
            1441-1563           AC164092.3         62066-62188         c
            1564-1667           AC164092.3         60904-61007         c
            1668-3654           AC164092.3         58328-60314         c
FEATURES             Location/Qualifiers
     source          1..3654
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 72.76 cM"
     gene            1..3654
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /note="golgi associated kinase 1A"
                     /db_xref="GeneID:245050"
                     /db_xref="MGI:MGI:3041196"
     exon            1..192
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..1878
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /note="isoform 3 precursor is encoded by transcript
                     variant 5; protein FAM198A; family with sequence
                     similarity 198, member A"
                     /codon_start=1
                     /product="Golgi-associated kinase 1A isoform 3 precursor"
                     /protein_id="NP_001395604.1"
                     /db_xref="GeneID:245050"
                     /db_xref="MGI:MGI:3041196"
                     /translation="MVSWIWRRLRGKKRSVMAFCLLMVLSAVAVIHFPPGHPASTPGL
                     NPMEPRGEVGASDPRIQQTLNSSLRQPARNLGHWTGQALPRNPILVCAKKQSRRRQVD
                     RSRHPLSVRRDAILSAQDRELLLEGEVRDAGGAALGQPGHNGLVQETQSKTVTMVVPL
                     TERSHESFQAQRDTAAASFRPWPADGRDPLPGAKNGVLTGGKAGSATSGSEAPWWSSS
                     AEDLQKSPWCGTETPGLAGTAAWGQVPPWFMEHDAQTLRLLVHGKVVGKARVPAHGQV
                     LQVGLSAGDALQDISPLRLSQFCSQGLCGLIKRSKDLHEVLSFHLDRVLGLQRSLPAV
                     ARSFHSPLLPYRYTDGSVRPIIWWAPDVQHLRDPDEDQNSLALGWLQYQALLARGCKW
                     PGQIPCLGIHHAEWARLALFDFLLQVHDRLDRYCCGFEPEPSDPCVEEGLREKCRNPE
                     ELRLVHILVRSSDPSRLVYIDNAGNLQHPEDKLNFRLLEGIDGFPESAVKVLASGCLQ
                     NLLFKSLQMDQVFWESQGGAAGLKHVLETLESRGQILLRHIKKHNLTLFRDKDP"
     exon            193..1440
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1563
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1667
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /inference="alignment:Splign:2.1.0"
     exon            1668..3654
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2112..2117
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
                     /note="hexamer: AATAAA"
     polyA_site      2129
                     /gene="Gask1a"
                     /gene_synonym="C730027P07Rik; Fam198a"
ORIGIN      
        1 gtgtgccaca ggactctgca gactcacacg tagactcaca tgcggagcat cctgtgttgt
       61 gtcctgccct gcaatctggt ggcggggaaa ggtgtggacc taatcccaac cctgcctgga
      121 aagtctgggc tccagggatg agtctgccag taggctgagc ccaggaacct gctgcagtac
      181 cgtggggaca tggtgtcttg gatctggaga aggcttcgtg gcaagaagcg gtcagtgatg
      241 gcattctgcc tcttgatggt cctgtctgca gtggctgtca ttcatttccc tccagggcat
      301 ccagcttcca ccccaggact taatcccatg gagcctcggg gggaagttgg tgcgtctgac
      361 cccaggattc agcagacttt gaactctagc ctgaggcagc cagcaaggaa cctgggccac
      421 tggacaggcc aggctttgcc cagaaatccc atcttggtct gtgccaagaa gcaaagccgc
      481 agaaggcaag tggacagaag ccgacaccca ctgagtgtca ggagagatgc gatactcagt
      541 gcccaggatc gtgagcttct attagagggg gaggtgagag atgcaggggg cgcagcgctg
      601 ggccagcctg ggcataatgg tttagtccaa gagacacaga gcaagacagt caccatggtt
      661 gtcccactca cagagagaag ccacgaatct tttcaggcac agagagatac tgctgcagca
      721 agctttaggc catggccagc agatggtaga gatcctttgc caggagccaa gaatggagtc
      781 ttgactggtg ggaaggctgg gagtgccacc tcagggtcag aggctccatg gtggtctagc
      841 tctgctgagg acctgcagaa atccccatgg tgtggtactg agacccctgg gctggccggc
      901 actgcagcat ggggtcaggt tccaccatgg ttcatggaac atgatgcaca aactctccgg
      961 ctactggtcc atgggaaagt ggtgggaaaa gccagggtcc ctgcccatgg gcaggtgctg
     1021 caggttggac tatctgctgg agatgccctc caggacatat ctcctctcag gctcagccag
     1081 ttctgctccc agggtctctg tggcctgatt aagaggtcca aggacctgca tgaagtccta
     1141 tccttccacc tggaccgtgt gctgggactc caacggagcc tacctgccgt agcccggagc
     1201 ttccacagtc cccttctgcc ctaccgttac acagatggca gtgtaaggcc catcatctgg
     1261 tgggcaccgg atgtgcagca cctaagagac ccagatgagg accagaactc tctggccctg
     1321 ggctggctac agtaccaggc cttgctggcc cgaggctgca aatggccagg ccagatccca
     1381 tgcctgggca tccaccatgc tgagtgggca cgtttggctc tctttgactt tctgcttcag
     1441 gtccacgacc gcctggatcg ctactgctgt ggcttcgagc ctgagccctc agacccctgt
     1501 gtggaagagg gtctccgaga aaaatgtcgg aacccagagg agctgcggct ggtccacatc
     1561 ctggtccgga gcagtgatcc atctcgcttg gtgtatatag acaatgctgg caaccttcag
     1621 catccagagg acaagctcaa ctttcggctg ctggaaggca tagatgggtt tccagagtcc
     1681 gctgtgaagg ttcttgcatc agggtgtcta cagaacctgc tgttcaagtc gctgcagatg
     1741 gaccaggtgt tctgggagag ccaaggtgga gctgcaggtc tgaagcatgt ccttgagact
     1801 ctggagagtc ggggacagat cctgctgaga cacattaaga agcacaacct cacactgttc
     1861 agggacaagg acccgtgagc ccaaggctgc ctgggccgag cacaccttgc tggagaactt
     1921 cacacaatgt aaacctcagc tggtgcgcgt ccctctcaat gacagcattt ctgtgacagt
     1981 agttggtcat cctgatgaca aatggggaga gccaaggctg gaggatccta cctcaccgtg
     2041 ggacaggtca cctgctgaag atgatggagg gcctgccgtc tccatgctct ggcagtttac
     2101 tctcacgcac caataaatat gttcaagaat gttcatgaac tgttccctgc acatgcgcat
     2161 gcagtgctgt gtgcatgtgt gcagagatat gtaggtatgt gcctgaacaa catcatgcat
     2221 cctaggcaag cactctacca gctgaactac ataccagaga agtctagttt ttaagattca
     2281 ttattttaat ttcaaaattt atatttatgt gcatgggtgt tttctctgac acacacacac
     2341 acacacacac acacacacac acattttgta ccatgtgtgt acctagtgtc tgcagaagcc
     2401 agaggagggt gtcaaacctc agggacttga gttacagata attgtgagct accatgtggg
     2461 ttctaagaat tgaacctgga tcctctggaa gagcaggcag tgctcttaac cactgagcca
     2521 tttctccagg cactaatttt atttttattt atgtttatgt ctgtgagtat ataccacgtg
     2581 tgtgaaggtg actatggaag ccagaagagg acagcagatt cattggaact ggagttactg
     2641 gagtggttgt gtgccaccgc gtacagatgc tgagatgaac tctttgtaga cccttctgag
     2701 agcaacagat gccctaaacc attgagccat ccctccagca gggagaagac tattataaaa
     2761 cccaagtccc cttcattaca tagatgttat cttcactttc atgctagcca ttgtgtgttt
     2821 taggctgact gttctgtttg tgcacaagag agctttgaat ctgagctgca ctcagccctg
     2881 gctgttagac ttgcccatgg ttcccctcag tctcccactt gggacttgac ctgtttgtct
     2941 tttgtgaaat aggaagccgt aattctgtgc agcccagttt gttcatgtta gcctgcgagc
     3001 ctctcagaac ggctctgctc ctccggtcat tgaaatgtca tttatttacc tcttttacat
     3061 gactgctcat ttgtatgaac cccatctgag agatcacttt ggtttcactg ccccagattc
     3121 cattcaagag tctattctgt tcccatctga aagtatactt ttatcagata aaaaccaagc
     3181 acacacaggc ccttttgtga gctgtgctgg gctgcactca cagggtttct taagagcctg
     3241 cttcaaaact gggcactgtt ctaatccaag ttactgtatt ctgctcggtg gtgtaaggat
     3301 ccacttaaac atctcttttt tgtatacgag tgttttgtct gcatgcacat ttgtgcactg
     3361 tacacgcaca gtgcccacag aagacagcag aggtaaccga ggcctctgga actggagtta
     3421 caatggtcgt gagctgcctc atgagtgcca gcaactgaag tttgcttctc cgcatcgctg
     3481 ctgagttctc tctttaagcc ctctagataa atatttatat gcctcttact agtctttcag
     3541 tagaaaacca aattttcagt tttatgtttt aatttctcct tatatatact gttttagggc
     3601 tttggttggg tcttgttttg ttgtttgaga ttaaaaaagg ctcagccaca tctc
//
