LOCUS       NM_172741               6215 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus granule associated Rac and RHOG effector 1 (Garre1),
            transcript variant 2, mRNA.
ACCESSION   NM_172741 XM_006539893
VERSION     NM_172741.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6215)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6215)
  AUTHORS   Bulfone,A., Carotenuto,P., Faedo,A., Aglio,V., Garzia,L.,
            Bello,A.M., Basile,A., Andre,A., Cocchia,M., Guardiola,O.,
            Ballabio,A., Rubenstein,J.L. and Zollo,M.
  TITLE     Telencephalic embryonic subtractive sequences: a unique collection
            of neurodevelopmental genes
  JOURNAL   J Neurosci 25 (33), 7586-7600 (2005)
   PUBMED   16107646
REFERENCE   3  (bases 1 to 6215)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX537302.12.
            
            On or before Apr 29, 2020 this sequence version replaced
            XM_006539893.4, NM_172741.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223969.7264.1,
                                           SRR10223971.7471.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                BX537302.12        176833-176888       c
            57-1308             BX537302.12        148043-149294       c
            1309-1506           BX537302.12        126894-127091       c
            1507-1647           BX537302.12        121354-121494       c
            1648-1743           BX537302.12        120973-121068       c
            1744-1905           BX537302.12        120688-120849       c
            1906-2064           BX537302.12        119753-119911       c
            2065-2162           BX537302.12        117328-117425       c
            2163-2288           BX537302.12        111448-111573       c
            2289-3301           BX537302.12        108307-109319       c
            3302-3467           BX537302.12        105581-105746       c
            3468-3605           BX537302.12        103850-103987       c
            3606-3684           BX537302.12        103085-103163       c
            3685-6215           BX537302.12        100048-102578       c
FEATURES             Location/Qualifiers
     source          1..6215
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 19.48 cM"
     gene            1..6215
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /note="granule associated Rac and RHOG effector 1"
                     /db_xref="GeneID:233103"
                     /db_xref="MGI:MGI:1924311"
     exon            1..56
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            57..1308
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     CDS             814..3993
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /codon_start=1
                     /product="granule associated Rac and RHOG effector protein
                     1"
                     /protein_id="NP_766329.1"
                     /db_xref="CCDS:CCDS21139.1"
                     /db_xref="GeneID:233103"
                     /db_xref="MGI:MGI:1924311"
                     /translation="MYCCSAQDNKMDYKRRFLLGGSKQKVQQHQQYPMPELGRALSAP
                     LASTAPSAPLGSLTAAGSCHHAMPHSTPIADIQQGISKYLDALNVFCRASTFLTDLFS
                     TVFRNSHYSKAAMQLKDVQEHVMEAASRLTSAIKPEIAKMLMELSAGAANFTDQKEFS
                     LQDIEVLGRCFLTVVQVHFQFLTHALQKVQPVAHSCFAEVVVPEKKNSSLSGMGHTPE
                     LEEAVRSWRGAAEATSRLRERGCDGCLAGIEVQQLFCSQSAAIPEHQLKELNIKIDSA
                     LQAYKIALESLGHCEYAMKAGFHLNPKAIEASLQGCCSEAEAQQTGRRQTPPQPMQCE
                     LPTVPVQIGSHFLKGVSFNESAADNLKLKTHTMLQLIKEAGCYNGITPRDDLPVTEVL
                     NQVCPSMWRGACKTAVQLLFGQAGLVVVDTAQIENKEAYAPQISLEGSRIVVQVPSTW
                     CLKEDPATMSLLQRSLDPEKTLGLVDVLYTAVLDLNRWRTGREQALPCIQIQLQRDIC
                     DFGNQADLPSGNGSKSSGLQKTFSKLTSRFTKKVSCTNSGSTHYSKNIFTAGCSEERA
                     KMMGNNIDTRLQSILNIGNFPRTTDPSQSSQNSSNPMVNGFLLERRENFLHGDDGKDE
                     KGMNLPTDQEMQEVIDFLSGFNMGQSHQGSPLVTRRNSTATAMVTEQKTGTMQPQQPS
                     LPLAPPLRPPQAGAHTPLAAQQGLAPQQQSPKQQQPQVQYYQHLLQPIGSQQTPPQPR
                     APAKWVHGSSQHPSQPMAAGLSPLGQWPGISDLSSDLYSLGLVSSYMDNMMSEVLGQK
                     PQGPRNNTWPNRDQSDGVFGMLGEILPFDPAVGSDPEFARYVAGVSQAMQQKRQAQHG
                     RRPGNPRGNWPPMEDAHRTWPLPEFFTEGDSLHSGWSGAQGDSASSSDETSSANGDSL
                     FSMFSGPDLVAAVKQRRKHSSGEQETSTLPSPPLLTTVEDVNQDNKTKTWPPKAPWQH
                     PSPMPSTLPSPAAPLYAVASPGSQWNDTVQMLQSPVWAAANDCNTTSFTYVQTPPQPP
                     PPPAHKAAPKGFKAFPGKAERRPAYLPQY"
     exon            1309..1506
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1647
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1743
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1905
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..2064
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            2065..2162
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            2163..2288
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            2289..3301
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            3302..3467
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            3468..3605
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            3606..3684
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     exon            3685..6215
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      5732
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /note="major polyA site"
     regulatory      6193..6198
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /note="hexamer: ATTAAA"
     polyA_site      6215
                     /gene="Garre1"
                     /gene_synonym="4931406P16Rik; mKIAA0355"
                     /note="major polyA site"
ORIGIN      
        1 acttccggtg tacacagccg gtccgggcgg tgcgccggag ccggggcgct tcgcaggaaa
       61 tgacttagag gccttatgaa tacatctgtg ctttcttgct tcagacttta caactgcagg
      121 ccaacccagt ctggaagcac tttttattaa tgttacaagg aaaccgctac ctcagcaaac
      181 aaaagaaagg agaagacaca caataacaaa tgccatgttt aaagaaaact tgttcccaga
      241 aacctttaca ggagatttgg aagtttttag cactgagaag cagctttcca ggtaaatgga
      301 tttgacaggc aggctctgtc agaattctgc agaggtgtgt tcttccttca ggacttcttg
      361 tgaagtaacc ccttccgcct aaatgctgtt gaccagctgg ggtccttttt ggtatataga
      421 agatacatta tattacattt taaaagttaa gttatttttc tgccattgta aatgtaagta
      481 tcaaaatatt cttgcaaagc aattataagc aaacactttc ctcagcaagc atatcttcat
      541 tgagggtagg atgctgaaca gttacagagc atttcggaca ctgttatttt tttgttagag
      601 ttcctgccta cactgaaaat attaattata taaatctgtt atttttctca cctttatgtt
      661 ggatcacatg gtcacctgcc tcatggaaat gcctttttta aaacttagat ttgcagaact
      721 ccactatttt tatacctagc tacagttttg gaaaaaaaaa aaggactcag aaccctgacc
      781 tgccagtggt ccccgggaca gttccccacc cgtatgtatt gctgcagtgc ccaggacaat
      841 aagatggact acaagcggcg cttcctgctt ggcgggtcca agcagaaggt gcagcagcac
      901 cagcagtacc cgatgcctga gctgggccga gcactgagcg ctcccctggc atccaccgcc
      961 ccctctgccc cgctgggcag tctgaccgct gcaggcagct gccaccatgc catgccccac
     1021 tctactccca ttgctgacat ccagcagggc atctctaagt acctggatgc cctcaatgtc
     1081 ttttgccgtg ctagtacgtt cctcacagat ctcttcagca ccgtgttcag gaactcacac
     1141 tactcaaagg ccgccatgca gctcaaagat gtgcaggaac atgtaatgga agcagccagc
     1201 agattgacct cagccataaa gcccgagatt gccaagatgc tcatggaact cagtgctggg
     1261 gctgcaaact tcacagatca gaaggaattc agtctccagg acattgaggt gttggggcga
     1321 tgtttcttga cagtggtgca agtccatttc cagtttttga cccacgcctt gcagaaagtc
     1381 cagccggtgg ctcactcttg ctttgctgag gtagttgtgc cagaaaaaaa gaacagcagt
     1441 ctgtctggca tgggccacac acctgaactg gaggaagctg tgcgatcctg gcgaggggca
     1501 gctgaggcga catctagatt gagagagaga ggctgtgatg gatgcctggc aggaatcgaa
     1561 gtccaacaac tcttttgttc tcaaagtgca gcaattcctg agcaccagct aaaagagcta
     1621 aacataaaaa tcgacagtgc tttgcaggct tataaaatag ctttggaaag cttaggccac
     1681 tgtgaatatg caatgaaagc tggcttccat ctaaacccaa aggccattga agcaagtttg
     1741 cagggctgct gcagtgaggc ggaagctcag cagacagggc gaaggcagac acccccacag
     1801 cccatgcagt gtgagctccc cacggttcct gtgcagatag gatcgcactt cctgaagggg
     1861 gtctccttta atgagtcggc tgccgacaat ctgaagctta agacgcatac catgttacag
     1921 ctcatcaagg aagcaggctg ctacaatgga atcacaccta gggatgatct tcctgtgact
     1981 gaagtcctga atcaggtgtg cccgtccatg tggcggggtg cctgtaagac tgctgtgcag
     2041 ctgctgttcg gccaggcagg gctggtggtt gttgacacag cacagattga aaataaagaa
     2101 gcctatgcac cccagatcag tcttgaaggt tccagaattg tggttcaagt cccatccaca
     2161 tggtgcttaa aggaagatcc tgctaccatg tccctgctgc agaggagcct ggatcccgag
     2221 aagaccctag gtctggtgga tgtgctttac acagccgtgc tagacctaaa ccgctggaga
     2281 acagggaggg aacaagcttt accctgtata cagatccagc tgcaaaggga tatctgcgat
     2341 tttgggaatc aggctgacct gccttctgga aatggaagca aatcctcggg actgcagaag
     2401 actttctcca aactgacatc ccggttcaca aagaaagtgt catgcaccaa ctctggcagc
     2461 acacactatt ccaaaaacat cttcacagct gggtgttcag aggaaagggc caaaatgatg
     2521 ggcaataata ttgatacacg gttacagagc attttgaaca ttggtaactt ccctaggact
     2581 acagaccctt cacagtcgtc tcagaattcc agtaatccaa tggtcaatgg ctttctcctg
     2641 gagagacgtg agaacttcct gcatggggat gatggcaagg atgagaaggg catgaactta
     2701 cccactgatc aggaaatgca ggaagtgata gattttctct caggctttaa catgggccag
     2761 tcccatcagg ggtccccact ggtgacaagg cgtaactcta ctgccactgc catggtgact
     2821 gaacagaaga caggaaccat gcaaccacag cagccatcac tgccattggc tcctccacta
     2881 cggccacccc aggctggagc acacacgcct ctggcagccc agcaaggtct ggctcctcag
     2941 cagcagtctc caaagcagca gcagccccaa gtccagtact accagcacct gctgcaaccc
     3001 attggatcac agcagactcc acctcagcct cgggcgcctg cgaaatgggt acatggctca
     3061 tctcagcacc catcacagcc catggcagcg ggtctgtctc ctcttggtca gtggcctggc
     3121 atatctgatc tcagctctga cttgtacagc ttgggtctag tgagcagcta tatggacaat
     3181 atgatgtcag aagttttggg acagaagccc cagggaccta gaaataacac ctggccaaac
     3241 cgtgaccaaa gtgatggagt ctttggaatg ctgggagaga ttttgccttt tgatcctgca
     3301 gtgggctcag acccagaatt cgcacgctat gtggcaggag tgagccaggc aatgcagcag
     3361 aagcggcaag ctcaacatgg ccgccggcca ggcaaccccc gtggcaactg gccgcccatg
     3421 gaagacgctc atcggacctg gcctttgcca gagttcttca cagaagggga cagcttgcac
     3481 agcggctggt caggagctca gggagactcg gccagttcca gtgatgagac ctcttcagcc
     3541 aatggggaca gtctgttctc catgttttca gggcctgacc ttgttgctgc tgttaaacag
     3601 agaaggaaac acagcagtgg agagcaggag accagcacac tgccctcacc acctctcctg
     3661 accacagtgg aggacgtgaa ccaggataac aaaaccaaaa cgtggccacc caaagcacca
     3721 tggcagcacc cttccccgat gcccagcacg ctgcccagcc cagctgcacc actctatgca
     3781 gtcgccagtc ctggcagcca gtggaacgac accgtgcaga tgctgcagtc ccctgtgtgg
     3841 gctgcagcca atgactgcaa taccacctcc ttcacctatg ttcagacacc accacagccc
     3901 ccacctccac cagcacataa ggcagcaccc aagggcttca aggccttccc tgggaaggct
     3961 gaacgtaggc cagcctattt gccccagtac tgactacagc tagcctgctg cccatcaaag
     4021 ctgttggggc aactgtcccc aaggctaact agctgatact agcccccaga aggaccagta
     4081 caccctgtcc cagggacaga aatattcctt gggtctgagg tgattggcag ctccaagtct
     4141 ttaaagcctg gtttctcaaa ctttgaaggt agcagacccc tgagagccag ctgaagatgg
     4201 agatttctga cactcagggg atgctggcaa tctgcatgct taataagcac ctcaggtaat
     4261 cctggtgcag gtggccagag gccacacttg ggaaaacaca gtctgaaggt agtcctgcat
     4321 gtgggaaagg catgaggcct gcaggctgag aacaaaactg accattcttt gaaactcttc
     4381 tctttaacac actgagtggg acccacaccc atcactaatt ttatagatat ttttcatgta
     4441 ggctttcggt taaaacgtct cctgcctaaa atgcagtggc tatcttaaga tccaggtaca
     4501 ctggctgaag gttagttagc tcagcactgt cttcatttaa gcttatataa gatgctagtg
     4561 atcagaagca accacctggc ttcccatggg tcagtagctc ctctgaagca cccaggggtg
     4621 caggctcatg taatgtacaa gagcgggatt gggcaactgc tgtcaggcat attctggcct
     4681 cccagggggt gcagctggtg catgctgagt gcacctgctg ccctcacttc cttccaccat
     4741 gaccagggca gcaccagcac cacgctcctc tacggaagga actgtggagg ggaggggttg
     4801 caccaagacc cccacactca gaaccacagt gacattgtga gctgactcag agacaaagga
     4861 attatgatgt agacaggaat tcaaaatctt tgtttagtca ccaacaacac ctcactttta
     4921 gttaatgtgt gccattaaac agatgacact ccatggattt ggggatattt tccagctaga
     4981 atggatccag aattgaatgg tgcttaaatt gagaaataat aaatatatct atatagagta
     5041 gacatttccc actatatatt aattgaggtt gcagaaggtt ctttatataa aacttattta
     5101 aaattttcat atttcatctt tgaaaatgtc taattgagaa aaatccatga tattttctgg
     5161 tatgaaagtt tgacagtatt aattttttta tattttctta aatcattaaa ccattttaat
     5221 atatgttaac tactaataaa tggtttattc tttctaactc catgtaagct tttccaatga
     5281 agattgtaat aacacatttt tgttctcatt tttctacaga taaatttata tttaaaaata
     5341 ccaaaaaaaa aaatccctat gtatacacac cacacacata cacacacaca gacacacatt
     5401 cacttataag aaaattatag aggacctgta gggtgagccc agccacctgc gtttttagta
     5461 ctgtgtctcc aggctgcctg aggcctcagc tgttgtcatt cgtgctgtgt gggggtgaca
     5521 tttctgcctg tagtgaagat ccttctcagt gggttcggaa tattcacctc accatgttta
     5581 cagagaacta ttttgtacat agagttttcc aggcacgtac tttgcaccag ccctgcgtgg
     5641 ctgttgtctg tgttagctgt cacagtgtgc acactaatct gttcagagtt ccttgtggct
     5701 gtttgacttg taaaaactgt gtatttcctt cagtaatgtg tccacagtgc tgtgtttcca
     5761 gttctagtct tctgcagtac tctcattttc atagtgcctc cctgaagacc tcaccttggg
     5821 ccaaggtcac tcctcggtgc cacagcacag gtgacactgc taattgtcat ctctggtctg
     5881 tctttctcta ttaaggaaga tatttgtctc cacggctgtg tgaccgtgtg aatcagcttg
     5941 tgtagtctcc acatgggtgc tgttcgaagc accaccttgc tctaaacact ggtgattcca
     6001 ggtgctgcgc ttggcagagg tgtcttgcca aagcgcatgt atgcgtgtga gtgtgtcctc
     6061 agcacggcca agcatggctg ccttgctcgg cattagcagg acatcatgtg aatagttgtg
     6121 accttccaaa actggaactc tacattttgt atcttacttt taaagctcct ataagtaaaa
     6181 taacttggct ttattaaaat atacatttaa taata
//
