LOCUS       NM_001355200            3772 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus GTPase activating RANGAP domain-like 3 (Garnl3),
            transcript variant 1, mRNA.
ACCESSION   NM_001355200 XM_006498481
VERSION     NM_001355200.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3772)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3772)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929197.6 and AL731852.9.
            
            On Sep 20, 2017 this sequence version replaced XM_006498481.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.132500.1,
                                           SRR1660821.89726.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-196               AL929197.6         2628-2823           c
            197-367             AL731852.9         24774-24944
            368-437             AL731852.9         43853-43922
            438-512             AL731852.9         65719-65793
            513-612             AL731852.9         75540-75639
            613-731             AL731852.9         77583-77701
            732-796             AL731852.9         83149-83213
            797-860             AL731852.9         84246-84309
            861-887             AL731852.9         88328-88354
            888-963             AL731852.9         95012-95087
            964-1062            AL731852.9         95668-95766
            1063-1166           AL731852.9         98624-98727
            1167-1275           AL731852.9         103609-103717
            1276-1321           AL731852.9         106263-106308
            1322-1428           AL731852.9         107029-107135
            1429-1544           AL731852.9         111181-111296
            1545-1649           AL731852.9         113008-113112
            1650-1724           AL731852.9         114537-114611
            1725-1836           AL731852.9         118286-118397
            1837-1935           AL731852.9         122450-122548
            1936-2052           AL731852.9         122883-122999
            2053-2231           AL731852.9         124570-124748
            2232-2390           AL731852.9         125855-126013
            2391-2457           AL731852.9         126952-127018
            2458-2565           AL731852.9         132034-132141
            2566-2684           AL731852.9         134632-134750
            2685-2823           AL731852.9         137536-137674
            2824-3039           AL731852.9         139018-139233
            3040-3166           AL731852.9         140165-140291
            3167-3772           AL731852.9         142967-143572
FEATURES             Location/Qualifiers
     source          1..3772
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.09 cM"
     gene            1..3772
                     /gene="Garnl3"
                     /note="GTPase activating RANGAP domain-like 3"
                     /db_xref="GeneID:99326"
                     /db_xref="MGI:MGI:2139309"
     exon            1..196
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..3341
                     /gene="Garnl3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     GTPase-activating Rap/Ran-GAP domain-like protein 3"
                     /codon_start=1
                     /product="GTPase-activating Rap/Ran-GAP domain-like
                     protein 3 isoform 1"
                     /protein_id="NP_001342129.1"
                     /db_xref="GeneID:99326"
                     /db_xref="MGI:MGI:2139309"
                     /translation="MEQEPGGAAAALLRQKRAALRRRGCSFESPSTAPQPPGPLMDPL
                     TKGSCGSQLAQTLLWKAKSSLSFGIQPLQTWPTKDPELESQVNLSVSEDLGCRRGDFS
                     RKHYGSVELLISSDADGAIQRAGRFRVENGSTDESAAALPGTWRRTDVHLENPEYHTR
                     WYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRVPQYRAILWRKTGTQKICLPY
                     SPTKTLSVKSILSAMNLDKFEKGPREIFHPEIQKDLLVLEEQEGSVNFKFGVLFAKDG
                     QLTDDEMFSNEIGSEAFQKFLNLLGDTITLKGWTGYRGGLDTKNNTTGINSVYTVYQG
                     HEVMFHVSTMLPYSKENRQQVERKRHIGNDIVTIVFQEGEESSPAFKPSMIRSHFTHI
                     FALVRYDQQNDNYRLKIFSEESVPLFGPPLPSPPVFTDHQEFRDFLLVKLINGEKATL
                     ETPTFAQKRRRTLDMLIRSLYQDLMPDLHKNMLNRRSFSDVLPESPKSARKKEEARQA
                     EFVRIGQALKLKSIVRGDAPSSLAASGMCKKEPWEPQCFCCNFPHEAVCADPWGQALL
                     VSTDAGVLLVDDDLPSVPVFDRTLPVKQIHVLETLDLLVLRADKGKDARLFVFRLSAV
                     QKGLDGRQTGRSRSDCRENKLEKTKGCHLYAINTHHSRELRIVVAIRNKLLLITRKPH
                     NKPSGVPGVSLLSPLSESPVEEFQYIREICLCDSPAVMALVDGPTEESDNLICVAYRH
                     QFDVVNESTGEAFRLHHVEANKVNFVAAIDVYEDGEAGLLLCYNYSCIYKKVCPFNGG
                     SFLLQPSASDFQFCWNQAPYAIVCAFPYLLAFTTDSMEIRLVVNGNLVHTAVVPQLQL
                     VASRSDIYFTAATTVHEGSSGGSSKGASAHTSPQTPPARDTPLFPSSLGEGEIQSKNL
                     YKIPLRNLVGRSIERPLKSPLVSKVITPPTSIGLGVAAIPVTHSLSLSRMEIKEIASR
                     TRRELLGLSDDGGTKTEGAPRAKSKTRKRLEESQGGPKPETVRSASSDRIPSGILESP
                     ASEANPEGHNHWASSEQDAGVDKEGSPGSGSSPFQLMASSEEDIIDLK"
     exon            197..367
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            368..437
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            438..512
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            513..612
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            613..731
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            732..796
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            797..860
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            861..887
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            888..963
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1062
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1166
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1275
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1321
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1428
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1544
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1649
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1724
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1836
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1837..1935
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2052
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2053..2231
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2232..2390
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2391..2457
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2458..2565
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..2684
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2685..2823
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            2824..3039
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3040..3166
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            3167..3772
                     /gene="Garnl3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3601..3606
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Garnl3"
                     /note="hexamer: AATAAA"
     polyA_site      3625
                     /gene="Garnl3"
                     /note="major polyA site"
     regulatory      3751..3756
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Garnl3"
                     /note="hexamer: TATAAA"
     polyA_site      3772
                     /gene="Garnl3"
ORIGIN      
        1 gggcggggcg tgggctgcgg cgcgctagct gagcgtccgg ccgaacaccg ccgaggcccg
       61 agcccacccg agtgtgcccg agccgtcggc ccccgcccgg ggcgatggag caggaacccg
      121 gcggggctgc cgctgcgctc ctgcggcaga agagggcggc gctgcggcgc agggggtgca
      181 gctttgagag tcccagcaca gcacctcagc ctccaggccc actgatggat ccactgacca
      241 aggggtcctg tgggagtcag ctggcacaaa ccctcctctg gaaagcgaag tcatctctct
      301 ctttcggcat ccagcccctt cagacttggc caacaaaaga tcctgaacta gagtcccagg
      361 tcaacctctc tgtctcagaa gacctaggct gtagacgtgg ggatttcagt aggaagcatt
      421 atggatctgt ggagctgctc atctctagtg atgccgatgg agccatccaa agggcaggaa
      481 gattccgagt ggagaatggc tctacagatg agagtgcagc tgctctgcca ggcacttggc
      541 gaaggacaga cgtgcactta gaaaacccgg agtaccacac ccggtggtat ttcaagtact
      601 ttttaggaca agtccatcag aattacattg gaaatgatgc agagaagagc cccttcttct
      661 tgtctgtcac cctttctgac cagaataatc agcgtgtccc tcagtatcgt gcaattcttt
      721 ggcggaaaac aggtacgcaa aaaatatgtc tcccctacag tcccacaaaa acgctgtctg
      781 tgaagtccat cttaagtgcc atgaacctgg acaagtttga gaaaggacct agggaaattt
      841 ttcatcccga gatacaaaag gacttgctgg ttctggaaga gcaggagggc tctgtgaatt
      901 tcaaatttgg ggttcttttt gccaaagatg ggcagctcac agatgacgag atgttcagca
      961 atgaaattgg aagtgaagct tttcaaaaat ttttaaatct cctcggtgac accattactc
     1021 taaagggctg gacaggctac cgtggcggtc tggacaccaa aaataacacc acagggatca
     1081 actcagtcta tactgtgtac caagggcatg aggtcatgtt tcacgtttcc accatgttgc
     1141 catattccaa agagaacaga cagcaggtgg aaaggaagcg ccacattgga aacgatattg
     1201 tcaccatcgt gttccaggaa ggagaggagt cctctcccgc ctttaagcct tccatgatcc
     1261 gctcccattt tacacatatt tttgccttag tgaggtatga ccagcaaaat gacaattaca
     1321 ggctgaaaat attttcagaa gaaagtgtgc cactttttgg cccacccttg ccatcccctc
     1381 cggtgtttac tgaccaccag gaattcaggg actttttgct tgtgaaatta attaacggtg
     1441 aaaaagccac tttggaaacc ccaacttttg cccagaaacg ccggcgtact ctggacatgt
     1501 tgatccgctc cttataccag gatttgatgc cggatttgca taagaatatg ctcaatcggc
     1561 gatcttttag tgatgtttta ccggagtcac ccaagtcagc acggaaaaaa gaggaggccc
     1621 ggcaggccga gtttgtgaga atagggcagg ccctgaagct caagtccatt gtgagagggg
     1681 acgccccatc aagcttggca gcatcaggga tgtgtaaaaa agagccttgg gagccccagt
     1741 gtttctgctg taatttccct catgaagccg tgtgtgcaga tccctggggc caggccttgc
     1801 tggtttccac ggatgctggc gtcttgctag tggacgatga cctcccatcc gtgcccgtgt
     1861 ttgacagaac tctacctgtg aagcagatcc acgtgctgga gaccctggac cttctggttc
     1921 tcagagcaga caaagggaaa gacgcccgcc tctttgtctt ccggctcagt gctgtgcaga
     1981 aaggccttga tggcaggcag actggaagga gcagatctga ctgccgagaa aacaagctgg
     2041 agaaaaccaa aggatgccac ctgtatgcta ttaatactca ccacagcaga gagctgagaa
     2101 tcgtggttgc aattcgcaat aaactgcttc tcatcacaag gaaaccacac aacaagccaa
     2161 gtggggtgcc aggtgtctca ctcctgtctc ccctgtcgga gtctcctgtt gaggaattcc
     2221 agtacatcag ggaaatctgc ctgtgtgact ccccagcagt gatggcctta gtggatggac
     2281 caacggaaga gagcgacaac ctcatctgtg tggcatatcg ccatcagttc gacgtggtaa
     2341 acgagagcac aggagaagcc tttaggctgc accatgtgga ggccaacaag gttaattttg
     2401 ttgcagctat tgatgtttat gaagatggag aagccggcct gctcctgtgc tacaactata
     2461 gttgcatcta taaaaaggtt tgccccttta acggtggctc ttttttgctt caaccctcgg
     2521 catcggattt ccagttctgt tggaaccagg ctccatatgc aattgtctgc gccttcccat
     2581 acctcctggc ctttactacc gactccatgg agatccgcct ggtggtgaat gggaacctgg
     2641 tccacacggc agttgtgcca cagctgcagc tcgtggcctc caggtcagat atatacttca
     2701 cagcagccac gactgtgcat gaaggctcat ctggaggcag ctcaaaggga gccagtgccc
     2761 acacgtctcc tcagacacca ccagcccggg acactccact gtttccttct tccctggggg
     2821 aaggtgaaat tcagtctaaa aatctgtaca agattccact tagaaacctt gtgggcagaa
     2881 gcatcgagcg acctctgaaa tcacccttag tctccaaggt catcaccccg cccacctcca
     2941 tcggccttgg agtcgctgcc attcctgtca cgcattcctt gtccctctcc cgcatggaaa
     3001 ttaaagagat tgcaagcagg acccgcaggg aactgctagg cctctctgat gatggtggaa
     3061 ccaaaacaga gggagcacca agggccaaat caaaaacccg gaagcggttg gaagaaagcc
     3121 aaggaggccc caagccagag actgtgaggt cagctagtag tgacaggatc ccatcaggaa
     3181 ttttggaaag tccggcatca gaagccaatc ccgagggcca caaccactgg gcaagttctg
     3241 agcaggacgc tggggtggat aaagagggca gcccgggctc aggcagcagc cccttccagc
     3301 tcatggcctc ctcagaggaa gacatcattg acttgaaata gagtctatgc cctattggcc
     3361 atccttagtt ttcttacgca aatttatact gttcaagcag ctccaacgtc cagtctcaac
     3421 acagcgcgcc ttcggccagg cagcgatcca cggaccaaac ctcctgcgcc ctcagccggt
     3481 gggtcacttc tccagtgtcc agtgccatct ttctcgaccc tgtttctttc cattcaagaa
     3541 ccgtcggtcc ccttgtaata aaggtggtag atttcattaa ggttttagat caaaactttg
     3601 aataaatcaa aaacgttcat tcttattctc tgcaaccctt ctcatatttt ataggtttag
     3661 atggaaatta tttttttcga aaattttgac ttatgtcata taatgtttct tttatggaaa
     3721 aaaagatgct gctttttaat tttactataa tataaataag ctttctttct tg
//
