LOCUS       NM_028169                842 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus golgi associated RAB2 interactor 5A (Garin5a),
            transcript variant 1, mRNA.
ACCESSION   NM_028169 XM_901475 XM_924733
VERSION     NM_028169.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 842)
  AUTHORS   Wang,H., Iida-Norita,R., Mashiko,D., Pham,A.H., Miyata,H. and
            Ikawa,M.
  TITLE     Golgi associated RAB2 interactor protein family contributes to
            murine male fertility to various extents by assuring correct
            morphogenesis of sperm heads
  JOURNAL   PLoS Genet 20 (6), e1011337 (2024)
   PUBMED   38935810
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 842)
  AUTHORS   Takahama,M., Fukuda,M., Ohbayashi,N., Kozaki,T., Misawa,T.,
            Okamoto,T., Matsuura,Y., Akira,S. and Saitoh,T.
  TITLE     The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate
            Immune Responses
  JOURNAL   Cell Rep 20 (12), 2944-2954 (2017)
   PUBMED   28930687
  REMARK    GeneRIF: the RAB2B-GARIL5 complex promotes IFN responses against
            DNA viruses by regulating the cGAS-STING signaling axis.
REFERENCE   3  (bases 1 to 842)
  AUTHORS   Fukuda,M., Kanno,E., Ishibashi,K. and Itoh,T.
  TITLE     Large scale screening for novel rab effectors reveals unexpected
            broad Rab binding specificity
  JOURNAL   Mol Cell Proteomics 7 (6), 1031-1042 (2008)
   PUBMED   18256213
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149607.6.
            
            On Feb 5, 2019 this sequence version replaced NM_028169.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC130017.1, AB473729.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-136               AC149607.6         53768-53903         c
            137-255             AC149607.6         53465-53583         c
            256-386             AC149607.6         52865-52995         c
            387-675             AC149607.6         50060-50348         c
            676-842             AC149607.6         49364-49530         c
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.83 cM"
     gene            1..842
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /note="golgi associated RAB2 interactor 5A"
                     /db_xref="GeneID:75538"
                     /db_xref="MGI:MGI:1922788"
     exon            1..136
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..732
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Golgi-associated Rab2B interactor-like 5; Protein FAM71E1;
                     family with sequence similarity 71, member E1; Golgi
                     associated RAB2 interactor protein 5A"
                     /codon_start=1
                     /product="Golgi-associated RAB2 interactor protein 5A
                     isoform 1"
                     /protein_id="NP_082445.1"
                     /db_xref="CCDS:CCDS52232.1"
                     /db_xref="GeneID:75538"
                     /db_xref="MGI:MGI:1922788"
                     /translation="MKGGRDLKAARGGADRPLAPAYAPCRPGRLQRHLLSGEFDQLRD
                     FPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPL
                     QFVQLFVHDESRQQLKVKFRTGRAFYLQLRSPPETRDCEFGRWVRLLYRLRFHSPTCA
                     VPFTHEDTAPEEEEEEEEEEEEEEVKEGQLQPPEFQATEARLDPQVSELWGL"
     exon            137..255
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /inference="alignment:Splign:2.1.0"
     exon            256..386
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /inference="alignment:Splign:2.1.0"
     exon            387..675
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /inference="alignment:Splign:2.1.0"
     exon            676..842
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      817..822
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /note="hexamer: AATAAA"
     polyA_site      842
                     /gene="Garin5a"
                     /gene_synonym="0610007G24Rik; 1700021N13Rik;
                     1700021P22Rik; Fam71e1; GARI-L5; GARIL5"
                     /note="major polyA site"
ORIGIN      
        1 accctattgt aaagtcacaa gctctaggcc ccacccttta tctgtctgtc ccaggcttca
       61 ctcggcgttc ctccccaggg ccggggcgtg gcgatgaagg gcggtcgaga tcttaaggcc
      121 gctcggggcg gagcagaccg ccccctggct ccagcctacg ccccgtgccg ccctgggcgc
      181 ctccaacgcc acctcctgag cggcgagttc gaccagctgc gcgactttcc catctttgaa
      241 agcaacttcg tgcaggtgac ccggtttgga gaagtcgcca acaaggtcac catgggggtg
      301 gcagcctcta gtcctgccct ggagctgcca gacctgctgc tgctggccgg ccctgacaag
      361 gagaatggac acctgcagct cctcgggctg tttcccttgc aatttgtgca gttgtttgtg
      421 catgatgaga gccgccagca gctcaaggtc aagttccgaa ctggccgcgc cttctacttg
      481 caactgcgct ctcctccaga gacccgcgac tgcgagtttg gccgctgggt gcggctgctc
      541 taccgcctgc gattccactc gcccacctgc gcagtgccct tcacgcacga ggacactgcg
      601 cctgaggaag aggaggagga ggaggaggag gaggaggagg aggaagtcaa ggaggggcag
      661 ttgcaacccc cggagtttca agccacagag gccagactcg acccgcaggt ctcagaactc
      721 tgggggctct gactcagaca agatccttcc agatcgccaa aggaccagaa atcaagtcag
      781 ctcagctcag agccagagag atggaatttt aaacttaata aagatcaggc tcttaaaacc
      841 ta
//
