LOCUS       NM_029069               1803 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus golgi associated RAB2 interactor 2 (Garin2),
            transcript variant 1, mRNA.
ACCESSION   NM_029069
VERSION     NM_029069.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Wang,H., Iida-Norita,R., Mashiko,D., Pham,A.H., Miyata,H. and
            Ikawa,M.
  TITLE     Golgi associated RAB2 interactor protein family contributes to
            murine male fertility to various extents by assuring correct
            morphogenesis of sperm heads
  JOURNAL   PLoS Genet 20 (6), e1011337 (2024)
   PUBMED   38935810
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1803)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1803)
  AUTHORS   Mo,S., Deng,K., Cao,C., Gui,Y. and Ma,Q.
  TITLE     FAM71D is dispensable for spermatogenesis and male fertility in
            mice
  JOURNAL   Mol Reprod Dev 90 (12), 804-809 (2023)
   PUBMED   37992210
REFERENCE   4  (bases 1 to 1803)
  AUTHORS   Ma,Q., Li,Y., Luo,M., Guo,H., Lin,S., Chen,J., Du,Y., Jiang,Z. and
            Gui,Y.
  TITLE     The expression characteristics of FAM71D and its association with
            sperm motility
  JOURNAL   Hum Reprod 32 (11), 2178-2187 (2017)
   PUBMED   29025071
REFERENCE   5  (bases 1 to 1803)
  AUTHORS   Fukuda,M., Kanno,E., Ishibashi,K. and Itoh,T.
  TITLE     Large scale screening for novel rab effectors reveals unexpected
            broad Rab binding specificity
  JOURNAL   Mol Cell Proteomics 7 (6), 1031-1042 (2008)
   PUBMED   18256213
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125057.5.
            
            On Apr 7, 2022 this sequence version replaced NM_029069.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014851.1, SRR5189685.202507.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-286               AC125057.5         54392-54677         c
            287-352             AC125057.5         46966-47031         c
            353-509             AC125057.5         35758-35914         c
            510-709             AC125057.5         33921-34120         c
            710-1289            AC125057.5         30685-31264         c
            1290-1528           AC125057.5         26551-26789         c
            1529-1557           AC125057.5         17920-17948         c
            1558-1592           AC125057.5         11979-12013         c
            1593-1803           AC125057.5         11668-11878         c
FEATURES             Location/Qualifiers
     source          1..1803
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 35.51 cM"
     gene            1..1803
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /note="golgi associated RAB2 interactor 2"
                     /db_xref="GeneID:70897"
                     /db_xref="MGI:MGI:1918147"
     exon            1..286
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            287..352
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            353..509
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..1676
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Golgi-associated Rab2B interactor-like 2; family with
                     sequence similarity 71, member D; protein FAM71D; Golgi
                     associated RAB2 interactor protein 2"
                     /codon_start=1
                     /product="Golgi-associated RAB2 interactor protein 2
                     isoform 1"
                     /protein_id="NP_083345.1"
                     /db_xref="CCDS:CCDS49096.1"
                     /db_xref="GeneID:70897"
                     /db_xref="MGI:MGI:1918147"
                     /translation="MMKKNRNKKAMNKQEALFIPHYYRLGHLKNILDGGEYAPYVSPP
                     ILESNFIQVNRRGESIYLHNRANWVTVGICSSNPIFKTPNMMLLAHLTPEARKEPEPL
                     FKTLLKSSSSGTLVLTRFIPLQFVTLSVHSAKNMRLKVKLINGRSYYLQLCAPVYKQD
                     IIFSQWVDLIPLLNQEKIKNTKVSEVSSLSELTNSTDIAGSMDITDITAFRELRPRHP
                     KTHRYPCNIMESADFSEYTDVTDVTDVTDVTDMLDNGITDVQDIKIVTEVTEVTEVTE
                     VTEVSEVSDVKMATNISGVKIVFENDDIIKTKQEEKEYTLKHRSLQDTKTKSDYQDSP
                     NPVTMSNIALALQDEGCFQTTQTPVKSKEDIYKEICDETSEENMIRLQNIHLKATESR
                     STRTDSDISDGELKLGRYLHKQCSSREQSFIHSLGSLPRGFVFLHLLL"
     exon            510..709
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            710..1289
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1528
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1557
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1592
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     exon            1593..1803
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1780..1785
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /note="hexamer: AATAAA"
     polyA_site      1803
                     /gene="Garin2"
                     /gene_synonym="4921509E07Rik; 4930516C23Rik; Fam71d;
                     GARI-L2"
                     /note="major polyA site"
ORIGIN      
        1 gtctgagctt ctcaggaatg ctggcagcag ccatctcagg ggctgtttgg tctttcagct
       61 gctcctgccc aatgctcttc ttacttcaga gctatgtcag cacattgtga tgcaggagca
      121 gtgaaataat gccaggctgc ccttcaccag ggacttagtt gcctgtccag cacacagaaa
      181 cacctctgct aaagaaatgt gaaagaagca gaaacgtgct atttggaaac aattctcctg
      241 tttgacatcc aggaggtttc caaagatcta tttcagcaga ttctatctac atcatgaaaa
      301 ggaggaagcc caaactgaag tgagtcacaa acttcattgg ccttgaggtg agcatgatga
      361 agaagaacag gaacaagaag gcaatgaata agcaagaagc cctctttatc ccacactatt
      421 acagactcgg gcatcttaag aacatattgg atggaggaga gtatgcccct tatgtatctc
      481 ctcctatact ggagagcaat tttattcagg tcaataggag aggtgaatct atttacctgc
      541 ataaccgagc aaactgggtg accgtaggca tctgttcttc caatcccatc ttcaagaccc
      601 ccaatatgat gctgttggca catctgacac cagaagctcg aaaagaacca gaacccctct
      661 ttaaaaccct tctgaagtct tcctcttcag ggactctggt gctcaccagg tttatccctc
      721 tgcagtttgt gactctctct gtgcacagtg ctaagaacat gcgtctcaag gtgaagctga
      781 tcaacggccg ctcctactac ttacagctct gtgctcctgt gtataaacag gatatcatat
      841 tttctcagtg ggtagacctc atccccctcc tgaatcagga gaaaatcaaa aataccaaag
      901 tctccgaggt ctcgagcctt tcagaactca caaacagcac ggacatcgca ggctcgatgg
      961 acatcacgga catcactgct ttcagagaac tgcggcccag gcacccgaaa acacacagat
     1021 acccttgtaa catcatggaa agtgcagact tctcagaata tacagatgtc actgatgtca
     1081 cagatgtcac tgatgtcacc gatatgctgg acaacgggat cacagatgtt caagatataa
     1141 aaattgtcac agaagtcaca gaagtcacag aagtcacaga agtcacagaa gtctcagaag
     1201 tctcagacgt caaaatggcc acaaacatct caggggtcaa aatagtattt gaaaacgatg
     1261 atataataaa gaccaagcag gaggaaaagg aatataccct gaaacatagg agtctacaag
     1321 atacaaaaac taagagtgac taccaagatt ccccaaatcc tgtcaccatg tcaaacatag
     1381 ccctggcttt gcaagatgaa gggtgttttc agactactca gactcctgta aaaagcaagg
     1441 aagacatata caaagaaata tgtgatgaaa cttctgaaga aaatatgatt cgtcttcaaa
     1501 acatacattt aaaggccacg gaatccagga gtacaagaac tgattcagac atttcagatg
     1561 gtgaactgaa gcttggaaga tatttgcaca agcagtgctc ctctagagaa caatccttta
     1621 tccactctct tggctcactg cccaggggat ttgtcttcct tcacctgctg ctctaaagat
     1681 ggaaagaatt tctttcctac ctccacatca agaaaaagac tcccatggca tcagcaagag
     1741 actacttact actggtgatg tgttaaaatc tgaagtacaa ataaacattt tgcaatttgg
     1801 aaa
//
