LOCUS       NM_001289663            1596 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus golgi associated RAB2 interactor 1B (Garin1b),
            transcript variant 1, mRNA.
ACCESSION   NM_001289663 XM_006505125
VERSION     NM_001289663.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1596)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1596)
  AUTHORS   Morohoshi,A., Miyata,H., Oyama,Y., Oura,S., Noda,T. and Ikawa,M.
  TITLE     FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome
            formation and male fertility in mice
  JOURNAL   Development 148 (21) (2021)
   PUBMED   34714330
  REMARK    GeneRIF: FAM71F1 binds to RAB2A and RAB2B and is essential for
            acrosome formation and male fertility in mice.
REFERENCE   3  (bases 1 to 1596)
  AUTHORS   Fukuda,M., Kanno,E., Ishibashi,K. and Itoh,T.
  TITLE     Large scale screening for novel rab effectors reveals unexpected
            broad Rab binding specificity
  JOURNAL   Mol Cell Proteomics 7 (6), 1031-1042 (2008)
   PUBMED   18256213
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133908.1, BC172086.1 and AC044807.4.
            
            On Jul 31, 2015 this sequence version replaced XM_006505125.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC172086.1, SRR5189685.204827.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AK133908.1         2-18
            18-1428             BC172086.1         1-1411
            1429-1596           AC044807.4         55549-55716
FEATURES             Location/Qualifiers
     source          1..1596
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 12.36 cM"
     gene            1..1596
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /note="golgi associated RAB2 interactor 1B"
                     /db_xref="GeneID:330277"
                     /db_xref="MGI:MGI:3032524"
     exon            1..308
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..1094
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Golgi-associated Rab2B interactor-like 1; testes
                     development-related NYD-SP18; protein FAM71F1; family with
                     sequence similarity 71, member F1; Golgi associated RAB2
                     interactor-like 1; Golgi associated RAB2 interactor
                     protein 1B"
                     /codon_start=1
                     /product="Golgi-associated RAB2 interactor protein 1B
                     isoform 1"
                     /protein_id="NP_001276592.1"
                     /db_xref="CCDS:CCDS80497.1"
                     /db_xref="GeneID:330277"
                     /db_xref="MGI:MGI:3032524"
                     /translation="MMTSVPPRKSWWTSKKTVKVIRSYPTFPSLNAWEKFRGLLPVDG
                     ETNPGVGLGVEEGLLCQMVHSPEFNLFPNSVVFESNFVQVRRSRNWKEIYKASNTMAL
                     GVTSSVPCLPLPNILLMARVKWHQGQSQTWNRPSRAPSINLKSILPLKFVELQIWDDQ
                     ERVLRLRTVTEKIYYLKLHPDHPETVFHFWIRLVQILHKGLSITTKDPTILVTHCLVP
                     KSLCSPGGKTELVQKKSKGLQPSESLTHLMAQGESETLSQIFSDLHQQKQYSSSRSEK
                     MHINKTSSEKATPCEDSIPCTCDLNWRDAFMFGEWERENPSGPQPLSLLGTLAASSRP
                     RLSLTGGNSI"
     exon            309..493
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /inference="alignment:Splign:2.1.0"
     exon            494..746
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /inference="alignment:Splign:2.1.0"
     exon            747..868
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /inference="alignment:Splign:2.1.0"
     exon            869..912
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1080
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1596
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1576..1581
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /note="hexamer: AGTAAA"
     polyA_site      1596
                     /gene="Garin1b"
                     /gene_synonym="Fam71f1; GARI-L1; Gm764; NYD-SP18"
                     /note="major polyA site"
ORIGIN      
        1 agaagggaag agacagatcc caggacaaca gtgcagaggg cccctgagca tgtgcagaca
       61 tgatgacatc agttccacct agaaagtctt ggtggacatc gaagaagaca gtaaaagtga
      121 taagatcata tccaaccttc ccttccttga atgcctggga gaagttcagg ggcctcttgc
      181 ctgtggatgg ggaaacgaac cctggagtgg gcctgggagt ggaggaagga ctactctgcc
      241 agatggttca ttctccagaa ttcaatctgt ttcctaactc cgtggtgttc gaaagcaact
      301 ttgttcaggt cagaaggagc agaaactgga aagaaatcta taaggcttcc aacacaatgg
      361 cccttggggt gacctcctcc gtaccttgcc ttccccttcc gaacatcctc cttatggcca
      421 gagtcaaatg gcatcagggg cagagccaga catggaacag accatccaga gcgccaagca
      481 tcaacctgaa gagcattctc cctttgaagt ttgtggagct ccagatctgg gacgaccagg
      541 aacgcgtcct gcggttgagg acagtcaccg agaaaatcta ctatctgaag ctccatcccg
      601 accaccctga gactgtcttc cacttttgga tccgcctggt tcaaattctg cataagggtc
      661 tgtccatcac caccaaggac cctaccatcc ttgtcactca ctgcctggta cccaagagcc
      721 tttgcagccc aggtggaaag actgagttag tgcagaagaa atcgaaaggc ctccagccca
      781 gtgagagcct cacacatctg atggcccagg gggagagcga gaccctctcc cagatctttt
      841 ccgacttgca tcagcagaaa cagtacagtt ccagcaggag cgaaaagatg cacatcaaca
      901 agaccagctc agagaaagct actccctgtg aagacagcat cccctgtacc tgtgatctca
      961 actggaggga tgcattcatg ttcggagaat gggaaagaga aaacccttct ggaccacagc
     1021 ccctctcact cctcggtact ctggctgcct ccagcaggcc acggctgtcc ctaactggag
     1081 gaaactctat atgatgcttc ctttcccatt ggggagagtt tatgcagccc gcaccagcac
     1141 ttctcttcag cattcagttt ctggggggct ctatttggac aaaggggagc aggaagttgc
     1201 tactaggagc gaaccagagt tatctcagca gcactgacaa gagcgcctcc tcattccgtc
     1261 agcctctccg tgtgttctca ccaccgcctc agaatacagc aacctgcacc cgtagccggg
     1321 cgatcagtca ggtcgattgg ggtgcactgt ccaaaagtct ggagcctgga gaagagcgat
     1381 gctatgcggc gagggaaagc aagcccggag gagcaggaac acggaagctg gtggagggag
     1441 ttggagaaga caggcagaaa gaaaataagt aacacaagga aacagaagag acctgggaga
     1501 aaagctgaag agaactagac aggaagtaca tctctgagag atgccccgcc aagcgtctat
     1561 ttatctaatt taaaaagtaa agccataaac cgagga
//
