LOCUS       NM_177713               2055 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus Grb2-binding adaptor, transmembrane (Gapt), mRNA.
ACCESSION   NM_177713 XM_906835 XM_920107
VERSION     NM_177713.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Chen,J.Q., Mori,H., Cardiff,R.D., Trott,J.F., Hovey,R.C.,
            Hubbard,N.E., Engelberg,J.A., Tepper,C.G., Willis,B.J., Khan,I.H.,
            Ravindran,R.K., Chan,S.R., Schreiber,R.D. and Borowsky,A.D.
  TITLE     Abnormal Mammary Development in 129:STAT1-Null Mice is
            Stroma-Dependent
  JOURNAL   PLoS One 10 (6), e0129895 (2015)
   PUBMED   26075897
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  AUTHORS   Liu,Y. and Zhang,W.
  TITLE     Identification of a new transmembrane adaptor protein that
            constitutively binds Grb2 in B cells
  JOURNAL   J Leukoc Biol 84 (3), 842-851 (2008)
   PUBMED   18559951
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK036534.1.
            
            On Apr 6, 2007 this sequence version replaced NM_177713.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036534.1, AK155882.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849388
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2055              AK036534.1         2-2056
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 61.87 cM"
     gene            1..2055
                     /gene="Gapt"
                     /gene_synonym="9830130M13Rik"
                     /note="Grb2-binding adaptor, transmembrane"
                     /db_xref="GeneID:238875"
                     /db_xref="MGI:MGI:3608341"
     exon            1..89
                     /gene="Gapt"
                     /gene_synonym="9830130M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            90..154
                     /gene="Gapt"
                     /gene_synonym="9830130M13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            155..2055
                     /gene="Gapt"
                     /gene_synonym="9830130M13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             543..1016
                     /gene="Gapt"
                     /gene_synonym="9830130M13Rik"
                     /note="growth factor receptor-bound protein 2-binding
                     adapter protein, transmembrane"
                     /codon_start=1
                     /product="protein GAPT"
                     /protein_id="NP_808381.1"
                     /db_xref="CCDS:CCDS26766.1"
                     /db_xref="GeneID:238875"
                     /db_xref="MGI:MGI:3608341"
                     /translation="MLECFESSPVAVAVGVSLLVLLLLCGIGCAWHWNRRESTPFTLP
                     KFMQRRSSRQKDVTKTVSSSAYVISPSMKASVESKGHKSTAKRNKMHGNYENVEVCPP
                     CTEGTTEKALYENTQPSNLEEHVYGNQTDPLYYNFQKPSPPPPQDDDIYILPDCD"
     regulatory      1206..1211
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gapt"
                     /gene_synonym="9830130M13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1227
                     /gene="Gapt"
                     /gene_synonym="9830130M13Rik"
                     /note="major polyA site"
ORIGIN      
        1 aagtttgatg aaaagtgaca gacagagttg gacactccca ggcttcatgt gagtccaact
       61 gatggaaagt ttttgggtaa tggaaaaagg tgttcgaatt tgctctagga atctaaagat
      121 gaaaagagct gagtcctgct gctcttgaga ccagcaggtt tctggacggc acctcccttt
      181 tcttgaggtt tctgctgtgc tgtaattctc tgctcacctc ggcttcattt tgtgatccac
      241 caagggtaaa ggaagtggag aggactaaaa atccaccccc ctccctccaa ttcagctcca
      301 gtgtacaggg atggtgatac agtaatcggt caccttcaga gactgaattt gttcagtctc
      361 acgtcgtcca gttgcatcgg gactttgcca gtaatgtcct ttgagatctg gaagagaaat
      421 gcctgcagga gccttccacc tcggttttga accgcagcca ccacgggcga ccagaaactg
      481 cctctgcttg tgcctgtgaa ttgattaacc acaccaaacc acggaacagc aactgtgcag
      541 aaatgctgga atgctttgag agttctccgg tggctgtggc tgtaggcgtt tccctcctag
      601 tcctcttgct gctctgtggg attggatgtg cttggcactg gaatcgcagg gaaagcacac
      661 cgtttaccct accgaagttt atgcaaagga gaagcagcag gcagaaagac gtcacaaaaa
      721 ccgtcagctc gagtgcctac gtgattagcc caagcatgaa agcctcggtg gaaagcaaag
      781 gccacaagtc tactgccaag agaaacaaga tgcatggcaa ctatgaaaat gtggaagtgt
      841 gccctccctg cactgaaggg acaactgaga aggccctgta tgaaaacacg cagccgtcta
      901 atctcgagga acacgtctac gggaatcaaa cggaccccct ctattataac ttccagaaac
      961 ctagccctcc tccgcctcaa gatgacgata tatacatcct tccagattgc gactagcttt
     1021 tcaacaaact gagactcgtt gctggaggaa aacccatcac caggcctccg agtggactga
     1081 tgtcgtcatg atcaaattat tctgatgaaa tcagtggtct ctttcctatt gccaccctta
     1141 tatatccaag aggatttata gacaagttct tgaacacccc cccacccccg tgtgccctgc
     1201 cttcaattaa atctgtattg ttttatattc atttttcttt tgaaatattt cctgtaactt
     1261 ccttcgtttt ttcctcgacc atcttttgag gctcagcact attgcagtct cctagcaggt
     1321 cgtcctgtgc tgaggggcta acccaagacc gttcacatgc caggtaagtg gtaaactcct
     1381 gagccacatc tctagtctgg tcttctgagt tccatccaat caaaagccta tgacgcagca
     1441 ggttgatctt cggaaaacat tctaggtggt cacttcatta atctgctaaa ataaaaagca
     1501 aaaaaaccaa acaaaacaaa acaaaaaaac aaacaaaaaa ctgtatgttg tttgcaaaag
     1561 atgtgaagct caaaacccta actccagaat tcatgacttt ttcagtcaca acttcctttg
     1621 tcagttattt cccctcaccc ctcactttct tgcttgcttc tgtgtcatca caaagctacc
     1681 aagtccctgt ctctgctcct ccacggtgtg acttggctgc ctctcaagcc tgcctcaggt
     1741 catttcttcc agcctccctc atttcaaacc tacacttcct tttatagacc ttgctgcctg
     1801 ttttgttttt gtttttgttt ttgagcattt gaagatatga aggtttgctg tgcattttac
     1861 tactaatgta atacgaggat tcttcatttg cagttaaaca gcaatgaagt ggtgcctagt
     1921 aatactttta gatccaaaga catcgtatgt ggaactaaaa gtctggttaa ttgaaaaaga
     1981 catgaatctt gcagtttgtc aagtagattt ttttctttta aaaaaaaaac taataaattt
     2041 actatttcta aatct
//
