LOCUS       NM_008083               1316 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Mus musculus growth associated protein 43 (Gap43), mRNA.
ACCESSION   NM_008083 XM_994895
VERSION     NM_008083.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Scavuzzo,M.A., Szlachcic,W.J., Hill,M.C., Ziojla,N.M., Teaw,J.,
            Carlson,J.C., Tiessen,J., Chmielowiec,J., Martin,J.F. and
            Borowiak,M.
  TITLE     Pancreatic organogenesis mapped through space and time
  JOURNAL   Exp Mol Med 57 (1), 204-220 (2025)
   PUBMED   39779976
REFERENCE   2  (bases 1 to 1316)
  AUTHORS   Zupancic,M., Keimpema,E., Tretiakov,E.O., Eder,S.J., Lev,I.,
            Englmaier,L., Bhandari,P., Fietz,S.A., Hartig,W., Renaux,E.,
            Villunger,A., Hokfelt,T., Zimmer,M., Clotman,F. and Harkany,T.
  TITLE     Concerted transcriptional regulation of the morphogenesis of
            hypothalamic neurons by ONECUT3
  JOURNAL   Nat Commun 15 (1), 8631 (2024)
   PUBMED   39366958
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1316)
  AUTHORS   Mao,Y., Meng,Y., Zou,K., Qin,N., Wang,Y., Yan,J., Chen,P.,
            Cheng,Y., Shi,W., Zhou,C., Chen,H., Sheng,J., Liu,X., Pan,J. and
            Huang,H.
  TITLE     Advanced paternal age exacerbates neuroinflammation in offspring
            via m6A modification-mediated intergenerational inheritance
  JOURNAL   J Neuroinflammation 21 (1), 249 (2024)
   PUBMED   39367406
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1316)
  AUTHORS   Maroto,I.B., Costas-Insua,C., Montero-Fernandez,C.,
            Hermoso-Lopez,A., Lebouc,M., Bajo-Graneras,R., Alvaro-Blazquez,A.,
            Blazquez,C., Cannich,A., Marsicano,G., Martin,R., Baufreton,J.,
            Rodriguez-Crespo,I., Bellocchio,L. and Guzman,M.
  TITLE     GAP43 Located on Corticostriatal Terminals Restrains
            Novelty-Induced Hyperactivity in Mice
  JOURNAL   J Neurosci 44 (39), e0701242024 (2024)
   PUBMED   39168654
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1316)
  AUTHORS   Lo Giudice,Q., Wagener,R.J., Abe,P., Frangeul,L. and Jabaudon,D.
  TITLE     Developmental emergence of first- and higher-order thalamic neuron
            molecular identities
  JOURNAL   Development 151 (18) (2024)
   PUBMED   39348458
REFERENCE   6  (bases 1 to 1316)
  AUTHORS   Robbins,M. and McKinney,M.
  TITLE     Transcriptional regulation of neuromodulin (GAP-43) in mouse
            neuroblastoma clone N1E-115 as evaluated by the RT/PCR method
  JOURNAL   Brain Res Mol Brain Res 13 (1-2), 83-92 (1992)
   PUBMED   1374507
REFERENCE   7  (bases 1 to 1316)
  AUTHORS   Ratty,A.K., Matsuda,Y., Elliott,R.W., Chapman,V.M. and Gross,K.W.
  TITLE     Genetic mapping of two DNA markers, D16Ros1 and D16Ros2, flanking
            the mutation site in the chakragati mouse, a transgenic insertional
            mutant
  JOURNAL   Mamm Genome 3 (1), 5-10 (1992)
   PUBMED   1581634
REFERENCE   8  (bases 1 to 1316)
  AUTHORS   Threadgill,D.S. and Womack,J.E.
  TITLE     Mapping HSA 3 loci in cattle: additional support for the ancestral
            synteny of HSA 3 and 21
  JOURNAL   Genomics 11 (4), 1143-1148 (1991)
   PUBMED   1783381
REFERENCE   9  (bases 1 to 1316)
  AUTHORS   Irving,N.G. and Brown,S.D.
  TITLE     Mouse chromosome-specific markers generated by PCR and their
            mapping through interspecific backcrosses
  JOURNAL   Genomics 11 (3), 679-686 (1991)
   PUBMED   1774069
REFERENCE   10 (bases 1 to 1316)
  AUTHORS   Irving,N.G., Hardy,J.A. and Brown,S.D.
  TITLE     The multipoint genetic mapping of mouse chromosome 16
  JOURNAL   Genomics 9 (2), 386-389 (1991)
   PUBMED   1672298
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC028288.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_994895.1, NM_008083.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC028288.1, AK031908.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 28.37 cM"
     gene            1..1316
                     /gene="Gap43"
                     /gene_synonym="B-50; Basp2; GAP-43"
                     /note="growth associated protein 43"
                     /db_xref="GeneID:14432"
                     /db_xref="MGI:MGI:95639"
     exon            1..179
                     /gene="Gap43"
                     /gene_synonym="B-50; Basp2; GAP-43"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..833
                     /gene="Gap43"
                     /gene_synonym="B-50; Basp2; GAP-43"
                     /note="brain abundant, membrane attached signal protein 2;
                     axonal membrane protein GAP-43; calmodulin-binding protein
                     P-57; growth accentuating protein 43"
                     /codon_start=1
                     /product="neuromodulin"
                     /protein_id="NP_032109.1"
                     /db_xref="CCDS:CCDS28177.1"
                     /db_xref="GeneID:14432"
                     /db_xref="MGI:MGI:95639"
                     /translation="MLCCMRRTKQVEKNDEDQKIEQDGVKPEDKAHKAATKIQASFRG
                     HITRKKLKGEKKGDAPAAEAEAKEKDDAPVADGVEKKEGDGSATTDAAPATSPKAEEP
                     SKAGDAPSEEKKGEGDAAPSEEKAGSAETESAAKATTDNSPSSKAEDGPAKEEPKQAD
                     VPAAVTDAAATTPAAEDAATKAAQPPTETAESSQAEEEKDAVDEAKPKESARQDEGKE
                     DPEADQEHA"
     exon            180..747
                     /gene="Gap43"
                     /gene_synonym="B-50; Basp2; GAP-43"
                     /inference="alignment:Splign:2.1.0"
     exon            748..1310
                     /gene="Gap43"
                     /gene_synonym="B-50; Basp2; GAP-43"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1246
                     /gene="Gap43"
                     /gene_synonym="B-50; Basp2; GAP-43"
                     /note="major polyA site"
ORIGIN      
        1 agagggaggg agagggaggg agggagggag agcgcgctag cgcgagagag cgagtgagca
       61 agcgagcaga aaagaggtgg agaggggggg aataaggaag agaggaggaa aggagagaag
      121 gcaggaagaa ggcaggggaa gataccacca tgctgtgctg tatgagaaga accaaacagg
      181 ttgaaaagaa tgatgaggac caaaagattg aacaagatgg tgtcaagccg gaagataagg
      241 ctcataaggc tgcgaccaaa attcaggcta gcttccgtgg acacataaca aggaaaaagc
      301 tcaaaggcga gaagaagggt gatgcaccag ctgctgaggc cgaggccaag gagaaggatg
      361 atgctcccgt tgctgatggt gtggagaaga aggagggaga tggctctgct actaccgatg
      421 cagccccagc caccagcccc aaggctgagg agcccagcaa ggcaggagat gcaccttctg
      481 aggagaagaa gggtgaaggg gatgcggccc cctccgagga aaaggccggc tcagcggaga
      541 cagaaagtgc tgctaaagct accactgata actccccgtc ctccaaggct gaagatggcc
      601 cagccaagga ggagcctaaa caagccgatg tgcctgctgc tgtcactgat gctgctgcca
      661 ccacccctgc tgcagaggat gctgccacca aggcagcgca gcctccaacg gagactgcag
      721 aaagcagcca agctgaggag gagaaagacg ctgtagacga agccaaacct aaggaaagtg
      781 cccgacagga tgagggtaaa gaagaccccg aggctgacca agaacatgcc tgaactttaa
      841 gaaatggctt tccacgttgc ccccacctga accctgtctc tcctgccctt ctcagctcca
      901 ctctgaagtt tcctctcctg tcctgctcac gtgtgtgagc ctgtcctctc ctacctatga
      961 gccctctctc tctgtgtggc aaacatttaa agaaaaaaaa aaagcaggaa agatcccaag
     1021 tccaacagtg tggcttaaac atttgtttct tggtgttgtt atggcgagtt tttggtaatg
     1081 atgatgcagt catcttggga aattcttgca ctgtaccccg gttttttgat ctggtgcgtg
     1141 tggccctgtg ggagtccact ttcctctcta tttctctctg ttccaagtgt gtgtgtgcaa
     1201 tgttccgttc tgaggagtcc aaaatattaa gtgaattcaa aaaccatttc tgtttcctca
     1261 ttttcaatgt gatggaatga acaaaaaggt taaaaaatta aaaaaaaaaa aaaaaa
//
