LOCUS       NM_015738               1245 bp    mRNA    linear   ROD 18-JUN-2024
DEFINITION  Mus musculus galanin receptor 3 (Galr3), mRNA.
ACCESSION   NM_015738 XM_001001042
VERSION     NM_015738.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Ortega,J.T., Parmar,T. and Jastrzebska,B.
  TITLE     Galanin receptor 3 - A new pharmacological target in retina
            degeneration
  JOURNAL   Pharmacol Res 188, 106675 (2023)
   PUBMED   36693600
REFERENCE   2  (bases 1 to 1245)
  AUTHORS   Locker,F., Bieler,L., Nowack,L.M.F., Leitner,J., Brunner,S.M.,
            Zaunmair,P., Kofler,B. and Couillard-Despres,S.
  TITLE     Involvement of Neuropeptide Galanin Receptors 2 and 3 in Learning,
            Memory and Anxiety in Aging Mice
  JOURNAL   Molecules 26 (7), 1978 (2021)
   PUBMED   33915732
  REMARK    GeneRIF: Involvement of Neuropeptide Galanin Receptors 2 and 3 in
            Learning, Memory and Anxiety in Aging Mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1245)
  AUTHORS   Brunner,S.M., Reichmann,F., Leitner,J., Wolfl,S., Bereswill,S.,
            Farzi,A., Schneider,A.M., Klieser,E., Neureiter,D., Emberger,M.,
            Heimesaat,M.M., Weghuber,D., Lang,R., Holzer,P. and Kofler,B.
  TITLE     Galanin receptor 3 attenuates inflammation and influences the gut
            microbiota in an experimental murine colitis model
  JOURNAL   Sci Rep 11 (1), 564 (2021)
   PUBMED   33436730
  REMARK    GeneRIF: Galanin receptor 3 attenuates inflammation and influences
            the gut microbiota in an experimental murine colitis model.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1245)
  AUTHORS   Tran,A., Loganathan,N., McIlwraith,E.K. and Belsham,D.D.
  TITLE     Palmitate and Nitric Oxide Regulate the Expression of Spexin and
            Galanin Receptors 2 and 3 in Hypothalamic Neurons
  JOURNAL   Neuroscience 447, 41-52 (2020)
   PUBMED   31730796
  REMARK    GeneRIF: Palmitate and Nitric Oxide Regulate the Expression of
            Spexin and Galanin Receptors 2 and 3 in Hypothalamic Neurons.
REFERENCE   5  (bases 1 to 1245)
  AUTHORS   Lee,Y.N., Reyes-Alcaraz,A., Yun,S., Lee,C.S., Hwang,J.I. and
            Seong,J.Y.
  TITLE     Exploring the molecular structures that confer ligand selectivity
            for galanin type II and III receptors
  JOURNAL   PLoS One 15 (3), e0230872 (2020)
   PUBMED   32231393
  REMARK    GeneRIF: molecular structures that confer ligand selectivity for
            galanin type II and III receptors
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1245)
  AUTHORS   Spazierer,D., Fuchs,P., Proll,V., Janda,L., Oehler,S., Fischer,I.,
            Hauptmann,R. and Wiche,G.
  TITLE     Epiplakin gene analysis in mouse reveals a single exon encoding a
            725-kDa protein with expression restricted to epithelial tissues
  JOURNAL   J Biol Chem 278 (34), 31657-31666 (2003)
   PUBMED   12791695
REFERENCE   7  (bases 1 to 1245)
  AUTHORS   Mahoney,S.A., Hosking,R., Farrant,S., Holmes,F.E., Jacoby,A.S.,
            Shine,J., Iismaa,T.P., Scott,M.K., Schmidt,R. and Wynick,D.
  TITLE     The second galanin receptor GalR2 plays a key role in neurite
            outgrowth from adult sensory neurons
  JOURNAL   J Neurosci 23 (2), 416-421 (2003)
   PUBMED   12533601
REFERENCE   8  (bases 1 to 1245)
  AUTHORS   Seltzer,Z., Wu,T., Max,M.B. and Diehl,S.R.
  TITLE     Mapping a gene for neuropathic pain-related behavior following
            peripheral neurectomy in the mouse
  JOURNAL   Pain 93 (2), 101-106 (2001)
   PUBMED   11427320
REFERENCE   9  (bases 1 to 1245)
  AUTHORS   Fuchs,P., Zorer,M., Rezniczek,G.A., Spazierer,D., Oehler,S.,
            Castanon,M.J., Hauptmann,R. and Wiche,G.
  TITLE     Unusual 5' transcript complexity of plectin isoforms: novel
            tissue-specific exons modulate actin binding activity
  JOURNAL   Hum Mol Genet 8 (13), 2461-2472 (1999)
   PUBMED   10556294
REFERENCE   10 (bases 1 to 1245)
  AUTHORS   Southard-Smith,E.M., Collins,J.E., Ellison,J.S., Smith,K.J.,
            Baxevanis,A.D., Touchman,J.W., Green,E.D., Dunham,I. and Pavan,W.J.
  TITLE     Comparative analyses of the Dominant megacolon-SOX10 genomic
            interval in mouse and human
  JOURNAL   Mamm Genome 10 (7), 744-749 (1999)
   PUBMED   10384052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC131952.1 and AL589670.21.
            
            On Apr 11, 2009 this sequence version replaced NM_015738.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC131950.1, SRR13422603.373641.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-761               BC131952.1         1-761
            762-762             AL589670.21        94843-94843         c
            763-1245            BC131952.1         763-1245
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.7 cM"
     gene            1..1245
                     /gene="Galr3"
                     /gene_synonym="Galnr3"
                     /note="galanin receptor 3"
                     /db_xref="GeneID:14429"
                     /db_xref="MGI:MGI:1329003"
     exon            1..406
                     /gene="Galr3"
                     /gene_synonym="Galnr3"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..1160
                     /gene="Galr3"
                     /gene_synonym="Galnr3"
                     /note="GAL3-R; GALR-3"
                     /codon_start=1
                     /product="galanin receptor type 3"
                     /protein_id="NP_056553.2"
                     /db_xref="CCDS:CCDS27631.1"
                     /db_xref="GeneID:14429"
                     /db_xref="MGI:MGI:1329003"
                     /translation="MADIQNISLDSPGSVGAVAVPVVFALIFLLGMVGNGLVLAVLLQ
                     PGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQAAIYTLDAWLFGAFVCKTVHLLI
                     YLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSY
                     YGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVTVVSLAYGRTLCFLWAAVGPA
                     GAAAAEARRRATGRAGRAMLTVAALYALCWGPHHALILCFWYGRFAFSPATYACRLAS
                     HCLAYANSCLNPLVYSLASRHFRARFRRLWPCGHRRHRHHHHRLHRALRRVQPASSGP
                     AGYPGDARPRGWSMEPRGDALRGGETRLTLSARGPQ"
     exon            407..1245
                     /gene="Galr3"
                     /gene_synonym="Galnr3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcctcctgt ctgaagaccc gttttctctt cctcgtttgc taggaaaatg gctgacatcc
       61 agaacatttc gctggacagc ccagggagcg taggggctgt ggcagtgccg gtggtctttg
      121 ccctcatctt cctgttgggc atggtgggta atgggctggt gttggccgtg cttctgcagc
      181 ctggcccaag tgcctggcag gaaccgggca gtaccacgga tctcttcatc ctcaacttgg
      241 cggtggccga cctttgcttc atcctgtgct gcgtgccctt ccaggcggcc atctacacac
      301 tggatgcctg gctctttggg gctttcgtgt gcaagacggt acatctgctc atctacctca
      361 ccatgtatgc cagcagcttc accctggcgg ccgtctcagt ggataggtac ctggcggtgc
      421 gacacccgct gcgctcccgg gccctccgca ccccgcgcaa cgcgcgcgcc gccgtggggc
      481 tcgtgtggct gctggcggcg ctcttttccg cgccctacct aagctactac ggcacggtgc
      541 gctacggcgc gctcgagctc tgcgtgcccg cctgggagga cgcgcggcgg cgcgcgctgg
      601 acgtggccac cttcgccgca ggctacctgc tgccggtgac cgtggtgagc ctggcctacg
      661 gacgcacgct gtgcttcctg tgggccgccg tgggtcccgc gggtgcggcg gcggcagagg
      721 cacgcagacg ggcaaccggc cgcgcggggc gcgccatgct gacggtggcc gcgctctacg
      781 cactctgctg gggcccgcac cacgcgctca tcctctgctt ctggtacggc cgcttcgcct
      841 tcagcccggc cacctacgcc tgtcgtctgg cttcgcactg cctcgcctac gccaactcct
      901 gcctcaaccc gctcgtctat tcccttgcct cccgccactt ccgcgcgcgc ttccgccgcc
      961 tgtggccctg cggccaccgc cgccaccgcc accaccacca ccgccttcat cgagccctcc
     1021 gtcgtgtcca gccggcgtct tcgggccccg ccggctatcc cggcgacgcc agacctcgcg
     1081 gttggagtat ggagcccaga ggggatgcct tgcgcggtgg agagactaga ctaaccctgt
     1141 ccgccagggg accgcaataa ccctgcctgc ttagactctg acagctgtcg gtctgtcttc
     1201 ttccctgggc agtagaatgt caccaaggag catctagggc atggc
//
