LOCUS       NM_010254               1957 bp    mRNA    linear   ROD 06-AUG-2024
DEFINITION  Mus musculus galanin receptor 2 (Galr2), mRNA.
ACCESSION   NM_010254
VERSION     NM_010254.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1957)
  AUTHORS   Li,D., Liu,Y., Li,C., Zhou,Z., Gao,K., Bao,H., Yang,J., Xue,G.,
            Yin,D., Zhao,X., Shen,K., Zhang,L., Li,J., Li,C., Song,J., Zhao,L.,
            Pei,Y., Xuan,L., Zhang,Y., Lu,Y., Zhang,Z.R., Yang,B., Li,Y. and
            Pan,Z.
  TITLE     Spexin Diminishes Atrial Fibrillation Vulnerability by Acting on
            Galanin Receptor 2
  JOURNAL   Circulation 150 (2), 111-127 (2024)
   PUBMED   38726666
  REMARK    GeneRIF: Spexin Diminishes Atrial Fibrillation Vulnerability by
            Acting on Galanin Receptor 2.
REFERENCE   2  (bases 1 to 1957)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1957)
  AUTHORS   Gong,Y., Laheji,F., Berenson,A., Qian,A., Park,S.O., Kok,R.,
            Selig,M., Hahn,R., Sadjadi,R., Kemp,S. and Eichler,F.
  TITLE     Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical
            Allodynia
  JOURNAL   Cells 11 (11), 1842 (2022)
   PUBMED   35681537
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1957)
  AUTHORS   Boal,F., Cinato,M., Timotin,A., Munzberg,H., Qualls-Creekmore,E.,
            Kramar,S., Loi,H., Roncalli,J., Keita,S., Tronchere,H. and
            Kunduzova,O.
  TITLE     Galanin Regulates Myocardial Mitochondrial ROS Homeostasis and
            Hypertrophic Remodeling Through GalR2
  JOURNAL   Front Pharmacol 13, 869179 (2022)
   PUBMED   35431947
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1957)
  AUTHORS   Locker,F., Bieler,L., Nowack,L.M.F., Leitner,J., Brunner,S.M.,
            Zaunmair,P., Kofler,B. and Couillard-Despres,S.
  TITLE     Involvement of Neuropeptide Galanin Receptors 2 and 3 in Learning,
            Memory and Anxiety in Aging Mice
  JOURNAL   Molecules 26 (7), 1978 (2021)
   PUBMED   33915732
  REMARK    GeneRIF: Involvement of Neuropeptide Galanin Receptors 2 and 3 in
            Learning, Memory and Anxiety in Aging Mice.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1957)
  AUTHORS   Mahoney,S.A., Hosking,R., Farrant,S., Holmes,F.E., Jacoby,A.S.,
            Shine,J., Iismaa,T.P., Scott,M.K., Schmidt,R. and Wynick,D.
  TITLE     The second galanin receptor GalR2 plays a key role in neurite
            outgrowth from adult sensory neurons
  JOURNAL   J Neurosci 23 (2), 416-421 (2003)
   PUBMED   12533601
REFERENCE   7  (bases 1 to 1957)
  AUTHORS   Davies,P.A., Wang,W., Hales,T.G. and Kirkness,E.F.
  TITLE     A novel class of ligand-gated ion channel is activated by Zn2+
  JOURNAL   J Biol Chem 278 (2), 712-717 (2003)
   PUBMED   12381728
REFERENCE   8  (bases 1 to 1957)
  AUTHORS   Costanzi,E., Beccari,T., Stinchi,S., Bibi,L., Hopwood,J.J. and
            Orlacchio,A.
  TITLE     Gene encoding the mouse sulphamidase: cDNA cloning, structure, and
            chromosomal mapping
  JOURNAL   Mamm Genome 11 (6), 436-439 (2000)
   PUBMED   10818207
REFERENCE   9  (bases 1 to 1957)
  AUTHORS   Pang,L., Hashemi,T., Lee,H.J., Maguire,M., Graziano,M.P., Bayne,M.,
            Hawes,B., Wong,G. and Wang,S.
  TITLE     The mouse GalR2 galanin receptor: genomic organization, cDNA
            cloning, and functional characterization
  JOURNAL   J Neurochem 71 (6), 2252-2259 (1998)
   PUBMED   9832122
REFERENCE   10 (bases 1 to 1957)
  AUTHORS   Kolakowski,L.F. Jr., O'Neill,G.P., Howard,A.D., Broussard,S.R.,
            Sullivan,K.A., Feighner,S.D., Sawzdargo,M., Nguyen,T., Kargman,S.,
            Shiao,L.L., Hreniuk,D.L., Tan,C.P., Evans,J., Abramovitz,M.,
            Chateauneuf,A., Coulombe,N., Ng,G., Johnson,M.P., Tharian,A.,
            Khoshbouei,H., George,S.R., Smith,R.G. and O'Dowd,B.F.
  TITLE     Molecular characterization and expression of cloned human galanin
            receptors GALR2 and GALR3
  JOURNAL   J Neurochem 71 (6), 2239-2251 (1998)
   PUBMED   9832121
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK053776.1, BC116982.1 and AW046646.1.
            
            On Nov 30, 2007 this sequence version replaced NM_010254.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK053776.1, AK132050.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1174              AK053776.1         2-1175
            1175-1711           BC116982.1         1132-1668
            1712-1957           AW046646.1         1-246               c
FEATURES             Location/Qualifiers
     source          1..1957
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 81.1 cM"
     gene            1..1957
                     /gene="Galr2"
                     /gene_synonym="mGalR"
                     /note="galanin receptor 2"
                     /db_xref="GeneID:14428"
                     /db_xref="MGI:MGI:1337018"
     exon            1..912
                     /gene="Galr2"
                     /gene_synonym="mGalR"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1940
                     /gene="Galr2"
                     /gene_synonym="mGalR"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcctttctg cctcttctgg gttggtctct ggagttcctt gtgtggcagg ctgaggtatt
       61 ccaaggattt agaaatggga gaggcctaga aatatggctg gccataacac tttgtgtttg
      121 ggggaagggg gcgttgaggg gtgaccaacc acagggccag taatctgtgt cagccccctc
      181 attccaagaa tgggatggat ctcttaaagg cgccccatgt cccacacgca ccctgctccc
      241 tccaccaatc caggaacagt gtgactcgct agtgaccgac tcaagtctaa agcagagcgg
      301 gtcccaggac ttgagcgcgg gagccaaatg gagtcagggt cattcgacag ctcctctctc
      361 ggctgcaggc cggagcgggg taccatccta tactctgggt gctcgctcct cctcccgtcc
      421 cccgcgcacc cctgctctgg ctcttggagc tcgacagtct tgctggggcg ctgcagccag
      481 ggagctacgc gctcaccaag acccggacgg ctgcgggagc cagggcggcg tctgctttgg
      541 tgataccatg aatggctcgg acagccaggg ggcggaggac tcgagccagg aaggtggcgg
      601 cggctggcag cccgaggcgg tcctcgtacc cctatttttc gcgctcatct tcctcgtggg
      661 cgctgtgggc aacgcgctgg tgctggcggt gctgctgcgc ggcggccagg cggtcagcac
      721 cacgaaccta ttcatcctca acctgggtgt ggccgacctg tgtttcatcc tgtgctgcgt
      781 gcctttccag gccaccatct ataccctgga cgattgggtg tttggctcac tgctctgcaa
      841 ggccgttcat ttcctcatct tcctcactat gcacgccagc agcttcacgc tggccgctgt
      901 ctcgctggac aggtatctgg ccatccgcta cccgctgcac tcccgagagt tgcgcacacc
      961 tcgaaacgcg ctggcggcca tcgggctcat ctgggggcta gcactgctct tctccgggcc
     1021 ctacctgagc tactacagtc agtcgcagct ggccaatctg acggtgtgcc acccagcgtg
     1081 gagcgcacca cgacgtcgcg ccatggacct ctgcactttt gtctttagct acctgttgcc
     1141 agtgctggtg ctcagcctga cctatgcgcg caccctgcac tacctctggc gcacagttga
     1201 cccagtagct gcaggctcag gttcccagcg cgccaagcgc aaggtgacac ggatgatcgt
     1261 catcgtggcg gtactcttct gcctctgttg gatgccccac cacgcgctta tcctctgcgt
     1321 gtggtttggt cgctttccgc tcacgcgtgc cacttacgcc ctgcgcatcc tttcacatct
     1381 agtatcttat gccaactcgt gtgtcaaccc catcgtttat gctctggtct ccaagcattt
     1441 ccgcaaaggt ttccgcaaaa tctgcgcggg cctgctacgc cgtgccccga ggagagcttc
     1501 aggccgagtg tgcatcctgg cgcctggaaa ccatagtggt ggcatgctgg aacctgagtc
     1561 cacagacctg acacaggtga gcgaggcagc cgggcccctc gtccccgcac ccgcacttcc
     1621 caactgcaca accttgagta gaaccctcga tccagcctgt taaaggacca aagggcatct
     1681 aacagcttct ggacagtgtg accagacgat acctgggggt catgcttgga tcttacaggg
     1741 ttgcagctaa agaccgagga ttgtagggaa ccttctgtta ttaaactgca cagattgcga
     1801 gagtggtgac atagcccttc catcctagca gctgggaagt ggaagcagga gcgagcagga
     1861 acaaagccag ccatcaagtt tgaggagtcc ttgaactacc tgagatccag tttgagcaaa
     1921 aataaaaaat ttaaaaggtt aaaaaaaaaa aaaaaaa
//
