LOCUS       NM_026449               1599 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus UDP-N-acetyl-alpha-D-galactosamine:polypeptide
            N-acetylgalactosaminyltransferase-like 5 (Galntl5), mRNA.
ACCESSION   NM_026449
VERSION     NM_026449.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1599)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1599)
  AUTHORS   Peluso,G., Tian,E., Abusleme,L., Munemasa,T., Mukaibo,T. and Ten
            Hagen,K.G.
  TITLE     Loss of the disease-associated glycosyltransferase Galnt3 alters
            Muc10 glycosylation and the composition of the oral microbiome
  JOURNAL   J Biol Chem 295 (5), 1411-1425 (2020)
   PUBMED   31882545
REFERENCE   3  (bases 1 to 1599)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 1599)
  AUTHORS   Takasaki,N., Tachibana,K., Ogasawara,S., Matsuzaki,H., Hagiuda,J.,
            Ishikawa,H., Mochida,K., Inoue,K., Ogonuki,N., Ogura,A., Noce,T.,
            Ito,C., Toshimori,K. and Narimatsu,H.
  TITLE     A heterozygous mutation of GALNTL5 affects male infertility with
            impairment of sperm motility
  JOURNAL   Proc Natl Acad Sci U S A 111 (3), 1120-1125 (2014)
   PUBMED   24398516
  REMARK    GeneRIF: mutated GALNTL5 has a role in male infertility with
            impairment of sperm motility
REFERENCE   5  (bases 1 to 1599)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005605.1 and AK016415.1.
            
            On Jul 22, 2009 this sequence version replaced NM_026449.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016415.1, AK006193.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1468              AK005605.1         22-1489
            1469-1599           AK016415.1         1470-1600
FEATURES             Location/Qualifiers
     source          1..1599
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 12.33 cM"
     gene            1..1599
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /note="UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase-like 5"
                     /db_xref="GeneID:67909"
                     /db_xref="MGI:MGI:1915159"
     exon            1..165
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            166..389
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..1492
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /note="UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase 15; polypeptide
                     N-acetylgalactosaminyltransferase-like 5; putative
                     polypeptide N-acetylgalactosaminyltransferase-like protein
                     5; galNAc-T15; pp-GaNTase 15; polypeptide GalNAc
                     transferase 15; protein-UDP
                     acetylgalactosaminyltransferase 15; UDP-GalNAc:polypeptide
                     N-acetylgalactosaminyltransferase 15"
                     /codon_start=1
                     /product="inactive polypeptide
                     N-acetylgalactosaminyltransferase-like protein 5"
                     /protein_id="NP_080725.2"
                     /db_xref="CCDS:CCDS19132.1"
                     /db_xref="GeneID:67909"
                     /db_xref="MGI:MGI:1915159"
                     /translation="MKSVIIQGLFCGFLAIGLWASMLLLFLHLEQEDMLENEKEELLK
                     KRSLGKNAHQQTRHSEDVTHDEVNFSDPELIQGLRRYGLNAIMSRRLGIEREVPDSRD
                     KICQQKHYPFNLPTASIIICFYNEEFNTLLRAVSSVVNLSPQHLLEEIILVDDMSEFD
                     DLKDKLDYYLEIFRGKVKLIRNKKREGLIRSKMIGASRASGDILVFLDSHCEVNRVWL
                     EPLLHAIAKDHKMVVCPIIDVINELTLDYMAAPIVRGAFDWNLNLRWDNVFAYELDGP
                     EGPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWMCGGQLFIL
                     PCSRVGYNSKALSQHRRANQSALSRNLLRVVHVWLDEYKGNFFLQRPSLTYVSCGNIS
                     ERVELRKRLGCKSFQWYLDNIFPELEPFNTERKRKKNRF"
     exon            390..507
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            508..674
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            675..797
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            798..1047
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1165
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1315
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1599
                     /gene="Galntl5"
                     /gene_synonym="1700021B12Rik; Galnt15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcctgtggt ggcctgctga acactctgtt gctgtaaggc aacccagcat gatctagtac
       61 cacctagaaa attacatctt ttcatcactc acagacctga ttccacttat gactctggtt
      121 gtcaaataac tttaaaagct gccagaaagg cagcctcatt gacaggaaat tagaacttaa
      181 aaatgtgaaa cccacaatga aaagtgtcat aattcagggt ttattctgtg gattcctggc
      241 catcgggctc tgggcatcta tgttactttt gtttttgcac cttgaacaag aagacatgct
      301 ggagaatgaa aaggaggaac tcctaaagaa gaggtcactc ggaaaaaatg cgcaccagca
      361 aacccgtcac tcagaggacg tcactcatga tgaggttaac ttttcagatc cagaacttat
      421 ccaaggattg aggcgatatg gattaaatgc catcatgagt agaagactgg gcatcgagag
      481 agaggtgcca gattccaggg ataaaatatg tcagcagaaa cactacccat tcaatctacc
      541 cactgccagc atcatcatat gcttctataa tgaagaattt aacaccttgc tccgggcagt
      601 gtcgagtgtg gtgaacctca gtccgcagca tctcctggag gagatcattc tggtggatga
      661 catgagtgaa tttgatgatt tgaaggacaa actggactat tatctggaaa tttttcgtgg
      721 aaaagttaaa ttaataagaa acaaaaagag agagggtctt atcagatcaa agatgattgg
      781 cgcctcccgg gcttcagggg acatcctggt gttcttggat agtcactgtg aggtgaatag
      841 agtctggcta gaacccttgc tgcatgccat tgctaaggat cacaaaatgg tggtatgccc
      901 tattatcgat gtcatcaatg aattaacctt ggattatatg gcggcaccta ttgtaagggg
      961 agcttttgac tggaatctga atctcagatg ggacaatgtt ttcgcatatg agttggacgg
     1021 cccagaagga ccaagtacac ctatccggtc acctgcaatg acaggaggaa tttttgctat
     1081 aaacagacat tattttaatg aacttggaca atatgacaac ggcatggata tttgtggagg
     1141 agaaaatgtg gaactttcgc taagaatctg gatgtgtgga ggccagctct tcatactccc
     1201 ttgctctcgg gttggatata acagtaaggc gctgagtcaa cacaggcgtg caaaccagag
     1261 tgccttgtca aggaatttac tgcgagtggt tcacgtctgg ctagatgaat acaagggaaa
     1321 cttttttctt caaagacctt ctttgacata cgtttcctgt ggaaatatta gtgagcgcgt
     1381 ggaattaagg aaacgcctgg gttgcaagtc attccagtgg tatttggata atatctttcc
     1441 agagttggag ccatttaaca cagagaggaa aaggaaaaaa aatcgtttct agttagtgaa
     1501 gggtgaaaat gtcccctaat tcttcaacat ctcgcaccac aggacaaatc tggagcatca
     1561 tgcaactatg taaaatgcaa tgaaaaatac attcagagt
//
