LOCUS       NM_145218               4196 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus polypeptide N-acetylgalactosaminyltransferase 17
            (Galnt17), mRNA.
ACCESSION   NM_145218 XM_917575 XM_925010 XM_925012 XM_925018 XM_925021
VERSION     NM_145218.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4196)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4196)
  AUTHORS   Chen,C.Y., Seward,C.H., Song,Y., Inamdar,M., Leddy,A.M., Zhang,H.,
            Yoo,J., Kao,W.C., Pawlowski,H. and Stubbs,L.J.
  TITLE     Galnt17 loss-of-function leads to developmental delay and abnormal
            coordination, activity, and social interactions with cerebellar
            vermis pathology
  JOURNAL   Dev Biol 490, 155-171 (2022)
   PUBMED   36002036
  REMARK    GeneRIF: Galnt17 loss-of-function leads to developmental delay and
            abnormal coordination, activity, and social interactions with
            cerebellar vermis pathology.
REFERENCE   3  (bases 1 to 4196)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4196)
  AUTHORS   Peluso,G., Tian,E., Abusleme,L., Munemasa,T., Mukaibo,T. and Ten
            Hagen,K.G.
  TITLE     Loss of the disease-associated glycosyltransferase Galnt3 alters
            Muc10 glycosylation and the composition of the oral microbiome
  JOURNAL   J Biol Chem 295 (5), 1411-1425 (2020)
   PUBMED   31882545
REFERENCE   5  (bases 1 to 4196)
  AUTHORS   Tian,E., Wang,S., Zhang,L., Zhang,Y., Malicdan,M.C., Mao,Y.,
            Christoffersen,C., Tabak,L.A., Schjoldager,K.T. and Ten Hagen,K.G.
  TITLE     Galnt11 regulates kidney function by glycosylating the endocytosis
            receptor megalin to modulate ligand binding
  JOURNAL   Proc Natl Acad Sci U S A 116 (50), 25196-25202 (2019)
   PUBMED   31740596
REFERENCE   6  (bases 1 to 4196)
  AUTHORS   Merla,G., Ucla,C., Guipponi,M. and Reymond,A.
  TITLE     Identification of additional transcripts in the Williams-Beuren
            syndrome critical region
  JOURNAL   Hum Genet 110 (5), 429-438 (2002)
   PUBMED   12073013
REFERENCE   7  (bases 1 to 4196)
  AUTHORS   Valero,M.C., de Luis,O., Cruces,J. and Perez Jurado,L.A.
  TITLE     Fine-scale comparative mapping of the human 7q11.23 region and the
            orthologous region on mouse chromosome 5G: the low-copy repeats
            that flank the Williams-Beuren syndrome deletion arose at
            breakpoint sites of an evolutionary inversion(s)
  JOURNAL   Genomics 69 (1), 1-13 (2000)
   PUBMED   11013070
REFERENCE   8  (bases 1 to 4196)
  AUTHORS   Kambouris,M., Sangameswaran,L., Triarhou,L.C., Kozak,C.A.,
            Dlouhy,S.R., Ghetti,B. and Hodes,M.E.
  TITLE     Molecular characterization of a novel cDNA from murine cerebellum,
            developmental expression, and distribution in brain
  JOURNAL   Brain Res Mol Brain Res 25 (3-4), 192-199 (1994)
   PUBMED   7808217
REFERENCE   9  (bases 1 to 4196)
  AUTHORS   Kambouris,M., Triarhou,L.C., Dlouhy,S.R., Sangameswaran,L., Luo,F.,
            Ghetti,B. and Hodes,M.E.
  TITLE     Novel cDNA clones obtained by antibody screening of a mouse
            cerebellar cDNA expression library
  JOURNAL   Brain Res Mol Brain Res 25 (3-4), 183-191 (1994)
   PUBMED   7808216
REFERENCE   10 (bases 1 to 4196)
  AUTHORS   Kambouris,M., Sangameswaran,L., Dlouhy,S.R., Hodes,M.E., Ghetti,B.
            and Triarhou,L.C.
  TITLE     Cellular distribution of the RNA transcripts of a newly discovered
            gene in the brain of normal, weaver, Purkinje cell degeneration and
            reeler mutant mice as evidenced by in situ hybridization
            histochemistry
  JOURNAL   Brain Res Mol Brain Res 18 (4), 321-328 (1993)
   PUBMED   8326827
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC069177.1 and AC118926.13.
            
            On Jul 14, 2006 this sequence version replaced NM_145218.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC069177.1, BC052469.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3034              BC069177.1         1-3034
            3035-4196           AC118926.13        64679-65840         c
FEATURES             Location/Qualifiers
     source          1..4196
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 70.66 cM"
     gene            1..4196
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /note="polypeptide N-acetylgalactosaminyltransferase 17"
                     /db_xref="GeneID:212996"
                     /db_xref="MGI:MGI:2137594"
     exon            1..1160
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1344
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1511
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1686
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1884
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..2002
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2188
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            2189..2326
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            2327..2422
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2590
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     exon            2591..4196
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4167..4172
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /note="hexamer: AATAAA"
     polyA_site      4196
                     /gene="Galnt17"
                     /gene_synonym="E330012B09Rik; Galnt19; Gcap8; Wbscr17"
                     /note="major polyA site"
ORIGIN      
        1 caactggtgt gactttggag gtccgactcc tccttccggc cagcctcgca acgcgccacc
       61 tcccgagaca agccagtgtg tccggcaggc cccggaggct cgtgtaggga cttggaacgt
      121 gtccgggaac ccgtggcgct gtgcgcactg gtgagttttg cgggcggggt gggggcggag
      181 aggacgtcgc gctgggtccc tgctcccgcc cctttcctgc tgtccccccc tccactttga
      241 gagagtcatt gagatttgag cgtgactgcg gagcctggag gatgcaggca cggggcgcgg
      301 ggttttcctc ttctcagagt gatggagaga gccggtgagc tgaacaaaga cacccgccct
      361 gaggagcggg tcctttgctg aagaactcta ttttcgccct gcgacggccg cctgcgggcg
      421 agagtgtcgg ccgcgcaact ccaggagtgg cgcgctcttc cgccggcggg cgcagagctg
      481 gagcccggca cctgcgcgcc actcccgcca catccccaga gcattccgac taccaaagga
      541 ttgttcctga aggtctacgt ctgcggagga ggtccaaagt ctaaaggcaa cctgtttgct
      601 gttctacagg gagagaccct gggaccttta tcttttgctg tcttgtagaa gggactgcgt
      661 gctgtggacg gagcaggcat ttcagagaca cttttgcaag ccaggggctt ccatgtgaga
      721 gatcagccgc gtccttccag tggttactgg cgccagagaa tcggcgtttt gtggtcaaca
      781 gcagctggga cccccagccc tttgccccct ccctcggcca ttgttcggtg tgtggggtct
      841 actccgtctc aggctgccct gcgcctcgca ggtgaggctg gtagaggcgt gggtccaggg
      901 aaaggaccgg ccgtgttgtt tgatggcttc actgaggaga gtcaaagtgt tgttggtgtt
      961 gaacttgatc gcggtggccg gcttcgtgat ctttttggct aagtgtcggc ctatcgcggt
     1021 gcgcagcgga gacgccttcc acgagatccg gcctcgcgca gaggtggcca acctcagcgc
     1081 gcacagcgcc agccccatcc aggatgcggt cctgaagcgc ttgtcgctgc tggaggacat
     1141 cgtctacagg cagcttaatg gcttatctaa atccctcggg ctcatcgaag ggtatggtgg
     1201 gaggggcaaa ggaggccttc ctgccaccct ttccccctct gaagaagaaa aagccaaagg
     1261 acctcatgag aaatatggct acaattccta cctcagtgaa aagatctcct tggaccggtc
     1321 tattccagat tatcgtccta ccaagtgtaa ggagctcaaa tattccaagg agttgcccca
     1381 gatatccatc atcttcatct tcgtgaatga ggccctgtct gtgatacttc ggtcagtcca
     1441 cagcgctgtc aatcacacac ccacacacct gctgaaggag atcatcctgg tggatgacaa
     1501 cagtgatgaa gaggagctga aggccccctt ggaagagtac gtccacaaac gctaccctgg
     1561 gctggtgaag gtggtacgca atcaaaagcg agaaggcctg atccgagcac gcatcgaggg
     1621 ctggaaagcg gccactggcc aggtcactgg ctttttcgat gctcacgtgg aattcactgc
     1681 tggctgggct gagcccgttc tgtcccgcat ccaggaaaac cggaagcggg tcatcctccc
     1741 ctccatcgac aacatcaagc aggacaactt cgaagtgcag cgctacgaga actccgccca
     1801 cgggtacagc tgggagctgt ggtgcatgta catcagcccc ccaaaagact ggtgggacgc
     1861 cggagatccc tctctcccca tcagaacacc agccatgatt ggctgctcat ttgtggtcaa
     1921 caggaaattc tttggtgaaa ttggtctgct ggaccctgga atggatgtgt acggaggaga
     1981 gaatattgaa cttgggatca aggtatggct ctgtggtggc agcatggagg tccttccatg
     2041 ttcaagggtg gcccacattg agcggaagaa gaaaccgtat aacagtaaca tcggctttta
     2101 caccaagagg aatgcattgc gagtagccga ggtctggatg gacgactaca agtcacatgt
     2161 gtacatagcg tggaatctgc ctctggagaa tccaggcatc gatatcggtg atgtctcaga
     2221 aagaaaagca ttaaggaaaa gtttgaaatg taagaatttc cagtggtatt tggaccatgt
     2281 ttacccagaa atgagaagat acaacaacac tatcgcctat ggggagcttc gtaataataa
     2341 ggccaaggac gtctgtctgg accaggggcc actggaaaac cacacagcaa tactgtaccc
     2401 atgccacggt tggggaccac agctcgcccg ctacaccaag gaagggttcc tgcacttagg
     2461 tgctctgggg accaccactc tcctccctga tacccgctgc ctggtggaca actccaagag
     2521 tcggttgccg cagctcctgg attgtgacaa ggtcaagagc agcttgtaca agcgttggaa
     2581 cttcatccag aatggagcca tcatgaataa gggcacaggg cgctgcctag aggtggagaa
     2641 ccggggcctg gccggcatcg acctaatcct tcgaagctgt actggacaga gatgggcaat
     2701 caagaatccc atcaagtaga tggacagaag gagggcacat ggagcccaga cccagggcag
     2761 ggcctggcca tcctcagaag cagccacatg gtggagagac agcaggcacc cagaggatgc
     2821 tctgtggacc tctcagggct cctccagagc agccctggat aaagatgtta cgtccccctc
     2881 aggcattctg cctgtgtact ttgaagatct tccccttatt ctcatctggg gaccaggggc
     2941 tacaacttct gggtactaat gggtgaggct gctcatatct ctccacggta tcatctccca
     3001 ccccagcatc agcagctggg ttctggcagg gtccctctcc ctccctccct ccctccctcc
     3061 ctccctccct ccctccctcc ctcccccctc ccttccttcc ttcctctctc cctccttccc
     3121 tccctctctc cctccctccc tccctctcca ctcttttctc tcatcctttg ctgcaactac
     3181 ttgtgtaact caccctggac ctccaagaca tggaggacaa tgagggcttt agccacatcc
     3241 tagctcctcc ctcttggaga aggaagcagt aagactccca agactccatt tctccttaag
     3301 acactttgcc ccagaggcct gtttgtatgc caaggcagca gccactcaga ccttctctgc
     3361 aaggtgactt tgagacaaga gttctggact cctctggatt gttcttgagg ttccctgtcc
     3421 cagtcaccca aagccctaaa tatggacagc atcagcgctt gagcctgtgt ctagagggag
     3481 ctggaagtca gctgctcatg ctggatgctc ctagcacctg gctagtacag cagctctgcc
     3541 tgccaaggac aaggtgccct ggtttcatgg agcagcaagg gtcttccatg caggacataa
     3601 gggctgaaga gtcagcctag tgatgggcac agggccctct gtgacgctta ctgctcagct
     3661 catttcaccc catgctttgc tggctgatgg gggacagaag cggccatttc ctcttttaag
     3721 agtgattgct tctttccaat tgccctctgg ttagggtgca cttataaatc agagttaata
     3781 tatggatgtg tctgcatgca cgggaaagca agagtgtgcc tgcctgagtg atgtgtgtgg
     3841 ctgggtgtat gtttgcgtgc ttgagcgtgc gagtgtgctt gagcagtagt ctcgggcttg
     3901 tagcttcatt gctcagtgga tagggacaag gacgcctaga agaatggggg gtgggaggca
     3961 tgtccctgga tcacgggccc agaggatatg tctgggtctt acatgctagg gtaacctttc
     4021 tctatcccct cctccaatcc actactgtcc ttggccatct cctgcccaga gccaaaccct
     4081 gtaggtgccc agtgtgggat ccagtatctc atttggtggt atctttattg gtgatcatct
     4141 ccttgcccca tctcccctcc ttgtggaata aatatgttag caatcccaca aagcaa
//
