LOCUS       NM_027864               2467 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus polypeptide N-acetylgalactosaminyltransferase 14
            (Galnt14), mRNA.
ACCESSION   NM_027864 XM_128787
VERSION     NM_027864.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2467)
  AUTHORS   Shu,T., Zhang,Y., Sun,T. and Zhu,Y.
  TITLE     Polypeptide N-Acetylgalactosaminyl transferase 14 is a novel
            mediator in pancreatic beta-cell function and growth
  JOURNAL   Mol Cell Endocrinol 591, 112269 (2024)
   PUBMED   38763428
  REMARK    GeneRIF: Polypeptide N-Acetylgalactosaminyl transferase 14 is a
            novel mediator in pancreatic beta-cell function and growth.
            Erratum:[Mol Cell Endocrinol. 2024 Sep 15;591:112291. doi:
            10.1016/j.mce.2024.112291.. PMID: 38838620]
REFERENCE   2  (bases 1 to 2467)
  AUTHORS   Iskusnykh,I.Y., Fattakhov,N., Li,Y., Bihannic,L., Kirchner,M.K.,
            Steshina,E.Y., Northcott,P.A. and Chizhikov,V.V.
  TITLE     Lmx1a is a master regulator of the cortical hem
  JOURNAL   Elife 12, e84095 (2023)
   PUBMED   37725078
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2467)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2467)
  AUTHORS   Peluso,G., Tian,E., Abusleme,L., Munemasa,T., Mukaibo,T. and Ten
            Hagen,K.G.
  TITLE     Loss of the disease-associated glycosyltransferase Galnt3 alters
            Muc10 glycosylation and the composition of the oral microbiome
  JOURNAL   J Biol Chem 295 (5), 1411-1425 (2020)
   PUBMED   31882545
REFERENCE   5  (bases 1 to 2467)
  AUTHORS   Tian,E., Wang,S., Zhang,L., Zhang,Y., Malicdan,M.C., Mao,Y.,
            Christoffersen,C., Tabak,L.A., Schjoldager,K.T. and Ten Hagen,K.G.
  TITLE     Galnt11 regulates kidney function by glycosylating the endocytosis
            receptor megalin to modulate ligand binding
  JOURNAL   Proc Natl Acad Sci U S A 116 (50), 25196-25202 (2019)
   PUBMED   31740596
REFERENCE   6  (bases 1 to 2467)
  AUTHORS   Tian,E., Stevens,S.R., Guan,Y., Springer,D.A., Anderson,S.A.,
            Starost,M.F., Patel,V., Ten Hagen,K.G. and Tabak,L.A.
  TITLE     Galnt1 is required for normal heart valve development and cardiac
            function
  JOURNAL   PLoS One 10 (1), e0115861 (2015)
   PUBMED   25615642
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2467)
  AUTHORS   Yoshida,C.A., Kawane,T., Moriishi,T., Purushothaman,A.,
            Miyazaki,T., Komori,H., Mori,M., Qin,X., Hashimoto,A., Sugahara,K.,
            Yamana,K., Takada,K. and Komori,T.
  TITLE     Overexpression of Galnt3 in chondrocytes resulted in dwarfism due
            to the increase of mucin-type O-glycans and reduction of
            glycosaminoglycans
  JOURNAL   J Biol Chem 289 (38), 26584-26596 (2014)
   PUBMED   25107907
REFERENCE   8  (bases 1 to 2467)
  AUTHORS   Tian,E., Hoffman,M.P. and Ten Hagen,K.G.
  TITLE     O-glycosylation modulates integrin and FGF signalling by
            influencing the secretion of basement membrane components
  JOURNAL   Nat Commun 3, 869 (2012)
   PUBMED   22643896
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 2467)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   10 (bases 1 to 2467)
  AUTHORS   Schilling,K. and Oberdick,J.
  TITLE     The treasury of the commons: making use of public gene expression
            resources to better characterize the molecular diversity of
            inhibitory interneurons in the cerebellar cortex
  JOURNAL   Cerebellum 8 (4), 477-489 (2009)
   PUBMED   19554387
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY733448.1, BC117800.1 and AK078292.1.
            
            On Jul 30, 2009 this sequence version replaced NM_027864.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK049598.1, AK078292.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-216               BY733448.1         1-216
            217-2180            BC117800.1         1-1964
            2181-2467           AK078292.1         1794-2080
FEATURES             Location/Qualifiers
     source          1..2467
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 44.88 cM"
     gene            1..2467
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /note="polypeptide N-acetylgalactosaminyltransferase 14"
                     /db_xref="GeneID:71685"
                     /db_xref="MGI:MGI:1918935"
     exon            1..521
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             393..2045
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /EC_number="2.4.1.41"
                     /note="galNAc-T14; pp-GaNTase 14; polypeptide GalNAc
                     transferase 14; protein-UDP
                     acetylgalactosaminyltransferase 14; UDP-GalNAc:polypeptide
                     N-acetylgalactosaminyltransferase 14;
                     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase 14"
                     /codon_start=1
                     /product="polypeptide N-acetylgalactosaminyltransferase
                     14"
                     /protein_id="NP_082140.2"
                     /db_xref="CCDS:CCDS28965.1"
                     /db_xref="GeneID:71685"
                     /db_xref="MGI:MGI:1918935"
                     /translation="MRRLTRRLALPIFGVLWITVLLFFWVTKRKLEVPLGPEVQTPKP
                     SDADWDDLWEQFDERRYLNAKKWRVGDDPYKLYAFNQRESERISSNRAVPDTRHKRCS
                     LLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPMHLIQEIILVDDFSNDPEDCK
                     QLIKLPKVKCLRNNERQGLVRSRMRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKE
                     DYTRVVCPVIDIINLDTFNYIESASELRGGFDWSLHFQWEQLSLEQKALRLDPTEPIR
                     TPIIAGGLFVIDKAWFDYLGKYDVDMDIWGGENFEISFRVWMCGGGLEIIPCSRVGHV
                     FRKKHPYVFPDGNANTYIKNTKRTAEVWMDEYKQYYYAARPFALERPFGNIENRLNLR
                     KNLHCQTFKWYLENVYPELRVPPDSSIQKGNIRQRQKCLESQKQKKQEILRLSPCAKV
                     KGDGAKSQVWAFTYTQQIIQEELCLSVVTLFPGAPVVLALCKNGDERQLWTKTGARIE
                     HIASHLCLDTDMFGDSTEDGKEVVVNPCESSLMSQHWDIVSS"
     exon            522..691
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            692..790
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            791..858
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            859..924
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1046
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1134
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1219
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1323
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1450
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1543
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1627
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1766
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1767..1886
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..2467
                     /gene="Galnt14"
                     /gene_synonym="0610033M06Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcctccgggg gtgccgggca cagcctcgga ttccaccttc ccggctgctc gagtcagttt
       61 ccctcgcggc agcagcgggc aaaggcagcc gcggcgcaca gcagcatcgc agcggccgcc
      121 gcggctctcc gtttggagcg ggcgccgggc tgagctgccc ctcgtccctg cccggccgcg
      181 tctctagtct ccggcgcccc tcgccgctcc gttcccggct gtggcttctc tccgaagcgg
      241 gcggggcagg atcccgccat ccaacatcgg gatcccagga gcagcgtttc tcctagagcg
      301 aggcgctcgg cagactcgtg ccccgccacc cctgaccgcc ggggggtgcc ccagggacgc
      361 gtcgccacca agagaagcag gcagagggga ccatgcggcg gctgactcgc cgcttggcgc
      421 tgcccatctt tggggtgctc tggatcaccg tactgctgtt cttctgggtc accaagagga
      481 agttggaggt gccgctggga cccgaagtgc agacccccaa gccttccgat gcggactggg
      541 atgacctgtg ggagcagttt gatgagcggc ggtatctgaa tgccaaaaag tggcgtgtcg
      601 gtgatgatcc ctacaaactg tatgctttca accaacggga gagtgagcgg atatcgagca
      661 atcgggctgt cccagacaca cgtcataaga gatgttcgct gcttgtgtat tgcacggacc
      721 ttcctcccac cagcatcatc atcaccttcc acaacgaggc acgttccact ctactcagaa
      781 ccatccgcag tgtgttaaac cgaaccccta tgcatctgat ccaggaaatc atattagtgg
      841 atgactttag caatgacccc gaggactgca agcaactcat caaattgccc aaggtgaagt
      901 gcttgcgcaa caatgagcgg caaggtctgg tccggtctcg gatgcgaggt gctgacattg
      961 cccaaggcac cactctgacc ttcctggaca gccattgtga ggtgaacagg gattggctgc
     1021 agcccctgtt acacagggtc aaagaggact acacaagggt tgtgtgccct gtgattgaca
     1081 tcattaacct ggataccttc aactatattg agtctgcctc agagctcaga gggggctttg
     1141 actggagcct gcacttccag tgggagcagc tctccctgga gcagaaagct ttgcgcctag
     1201 accctactga gcccatccgg actccaatca tagccggagg gctcttcgtg atcgacaaag
     1261 cctggttcga ttacctgggt aaatatgacg tcgacatgga catctggggt ggggagaact
     1321 ttgaaatctc tttccgagtg tggatgtgtg gaggtggcct ggagatcatc ccttgcagcc
     1381 gggtgggaca tgtcttcaga aaaaagcatc cttatgtttt ccccgatggg aacgccaaca
     1441 catatataaa gaacaccaag aggacagctg aagtatggat ggatgaatac aagcagtact
     1501 actatgcagc tcggcctttt gccctggaga gaccctttgg aaacattgag aacaggctga
     1561 acctgaggaa gaatcttcac tgccagacct tcaagtggta cctagagaat gtctacccag
     1621 aactcagggt ccccccagac tcctccatcc agaagggcaa tatccggcag cggcagaagt
     1681 gccttgagtc tcaaaagcag aaaaaacagg agattctcag gctaagtccc tgtgccaagg
     1741 tcaaaggaga tggagcaaag tctcaggtgt gggccttcac atacacccag cagatcatcc
     1801 aagaagagct gtgcctgtcc gtggtcaccc tgtttcctgg tgcccccgtg gttcttgctc
     1861 tatgcaagaa tggggatgaa aggcagctat ggaccaagac tggtgcccga attgagcaca
     1921 tagcatctca cctctgcctg gatacagaca tgtttggtga cagcaccgag gatggcaagg
     1981 aggtcgttgt caacccttgt gagtcgtcgc tcatgagcca gcactgggac attgtgagct
     2041 catgaggacc ctgggtgcat tcaactgtgg accaggaatg atgcttccct ggaccaaacc
     2101 aaactggaac ccaggttgtg aacagctcat gactgcaccc gatgtcctcg actggaggta
     2161 gagcaaaggc tcccaggaca ggagcaacag tctcagggaa gatggaggaa aaggtcacaa
     2221 accagcaggg ctcagtgaca ccctcatgtg tgcaatatta tgaaggtcca gtcctggcca
     2281 ggttttctga ttgggacctg gagatggaga tccgatggga agtgtttgtt gtaccctttc
     2341 ttacaaaaca agacacctta tggaggcttg tcttgaaagc tgtccttgtc actgtgccag
     2401 gacgacatgg agagatgcac aatagagatg gtttacagaa caaataaagc taactttggg
     2461 aattgtc
//
