LOCUS       NM_134189               4725 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus polypeptide N-acetylgalactosaminyltransferase 10
            (Galnt10), mRNA.
ACCESSION   NM_134189
VERSION     NM_134189.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4725)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4725)
  AUTHORS   Peluso,G., Tian,E., Abusleme,L., Munemasa,T., Mukaibo,T. and Ten
            Hagen,K.G.
  TITLE     Loss of the disease-associated glycosyltransferase Galnt3 alters
            Muc10 glycosylation and the composition of the oral microbiome
  JOURNAL   J Biol Chem 295 (5), 1411-1425 (2020)
   PUBMED   31882545
REFERENCE   3  (bases 1 to 4725)
  AUTHORS   Tian,E., Wang,S., Zhang,L., Zhang,Y., Malicdan,M.C., Mao,Y.,
            Christoffersen,C., Tabak,L.A., Schjoldager,K.T. and Ten Hagen,K.G.
  TITLE     Galnt11 regulates kidney function by glycosylating the endocytosis
            receptor megalin to modulate ligand binding
  JOURNAL   Proc Natl Acad Sci U S A 116 (50), 25196-25202 (2019)
   PUBMED   31740596
REFERENCE   4  (bases 1 to 4725)
  AUTHORS   Vincentz,J.W., Firulli,B.A., Toolan,K.P., Arking,D.E.,
            Sotoodehnia,N., Wan,J., Chen,P.S., de Gier-de Vries,C.,
            Christoffels,V.M., Rubart-von der Lohe,M. and Firulli,A.B.
  TITLE     Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA
            Transcription Factor Binding and Disrupts Conduction System
            Development and Function
  JOURNAL   Circ Res 125 (6), 575-589 (2019)
   PUBMED   31366290
REFERENCE   5  (bases 1 to 4725)
  AUTHORS   Tian,E., Stevens,S.R., Guan,Y., Springer,D.A., Anderson,S.A.,
            Starost,M.F., Patel,V., Ten Hagen,K.G. and Tabak,L.A.
  TITLE     Galnt1 is required for normal heart valve development and cardiac
            function
  JOURNAL   PLoS One 10 (1), e0115861 (2015)
   PUBMED   25615642
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4725)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
REFERENCE   7  (bases 1 to 4725)
  AUTHORS   Nelson,P.A., Sutcliffe,J.G. and Thomas,E.A.
  TITLE     A new UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA
            exhibits predominant expression in the hypothalamus, thalamus and
            amygdala of mouse forebrain
  JOURNAL   Brain Res Gene Expr Patterns 1 (2), 95-99 (2002)
   PUBMED   15018805
  REMARK    GeneRIF: GALNT10 exhibits predominant expression in the
            hypothalamus, thalamus and amygdala of mouse forebrain
REFERENCE   8  (bases 1 to 4725)
  AUTHORS   Ten Hagen,K.G., Bedi,G.S., Tetaert,D., Kingsley,P.D., Hagen,F.K.,
            Balys,M.M., Beres,T.M., Degand,P. and Tabak,L.A.
  TITLE     Cloning and characterization of a ninth member of the
            UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family,
            ppGaNTase-T9
  JOURNAL   J Biol Chem 276 (20), 17395-17404 (2001)
   PUBMED   11278534
REFERENCE   9  (bases 1 to 4725)
  AUTHORS   Kingsley,P.D., Hagen,K.G., Maltby,K.M., Zara,J. and Tabak,L.A.
  TITLE     Diverse spatial expression patterns of UDP-GalNAc:polypeptide
            N-acetylgalactosaminyl-transferase family member mRNAs during mouse
            development
  JOURNAL   Glycobiology 10 (12), 1317-1323 (2000)
   PUBMED   11159923
REFERENCE   10 (bases 1 to 4725)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB626609.1, BC060617.1 and AK033515.1.
            
            On Apr 29, 2004 this sequence version replaced NM_134189.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060617.1, AK131155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                BB626609.1         1-17
            18-3165             BC060617.1         1-3148
            3166-3265           AK033515.1         2824-2923
            3266-4725           BC060617.1         3249-4708
FEATURES             Location/Qualifiers
     source          1..4725
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 35.27 cM"
     gene            1..4725
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /note="polypeptide N-acetylgalactosaminyltransferase 10"
                     /db_xref="GeneID:171212"
                     /db_xref="MGI:MGI:1890480"
     exon            1..276
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1929
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /EC_number="2.4.1.41"
                     /note="UDP-N-acetyl-alpha-D-galactosamine: polypeptide
                     N-acetylgalactosaminyltransferase 9; pp-GaNTase 10;
                     polypeptide GalNAc transferase 10; protein-UDP
                     acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide
                     N-acetylgalactosaminyltransferase 10;
                     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase 10"
                     /codon_start=1
                     /product="polypeptide N-acetylgalactosaminyltransferase
                     10"
                     /protein_id="NP_598950.2"
                     /db_xref="CCDS:CCDS24719.1"
                     /db_xref="GeneID:171212"
                     /db_xref="MGI:MGI:1890480"
                     /translation="MRRKEKRLLQAVALALAALVLLPNVGLWALYRERQPDGSPGGLG
                     AAVAPAAVQELHSRQKKTFFLGAEQRLKDWHNKEAIRRDAQRVGYGEQGKPYPMTDAE
                     RVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSS
                     LLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLI
                     RTRMLGASAATGDVVTFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRY
                     ETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGG
                     YDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKR
                     VAEVWMDEYAEYIYQRRPEYRHLSAGDVVAQKKLRVSLNCKSFKWFMTKIAWDLPKFY
                     PPVEPPAAAWGEIRNVGTGLCTDTKLGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWR
                     EDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDC
                     SESDHRVFMNTCNPSSLTQQWLFEHTNSTVLENFNKN"
     exon            277..379
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            380..518
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            519..685
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            686..871
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            872..1055
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1173
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1281
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1503
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1620
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1770
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..4702
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4678..4683
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /note="hexamer: AATAAA"
     polyA_site      4702
                     /gene="Galnt10"
                     /gene_synonym="C330012K04Rik; GalNAc-T10; GalNAc-T9;
                     Galnt9; ppGaNTase"
                     /note="major polyA site"
ORIGIN      
        1 ggagttggag cggggccggc gtcgcggccg ctactgctgg ccgaactgct gccgccgccg
       61 ggtggacggg cggacgcgca aagccggggg cgggcgcggc ggggcggacc ggccccgatg
      121 aggcgcaaag agaagcggct cttgcaggcg gtggctctgg ctctggcggc cctggtcctg
      181 ctgcccaacg tggggctttg ggctctgtac cgcgagcggc agcccgacgg cagccctggg
      241 ggattggggg cggcggtggc ccccgcggcg gttcaggaat tacacagtcg acaaaaaaag
      301 acatttttct tgggagctga acaaaggctg aaggactggc ataacaagga ggctatcagg
      361 agggacgcac agcgcgtagg atatggagaa caggggaagc cttaccccat gaccgatgcc
      421 gagagagtgg accaggcgta ccgggaaaat ggatttaaca tctacgtcag tgataaaatc
      481 tccctgaatc gctctctccc cgatatccgg cacccaaact gtaacagcaa gctctacctg
      541 gagacgctcc ccaacaccag catcatcatc cccttccaca acgagggctg gtcctcactg
      601 ctgcgcactg ttcacagcgt gctcaaccgc tcgcccccag agctagtggc ggagattgtg
      661 ttggtcgatg acttcagtga tcgagagcac ctgaagaagc ccctggagga ctacatggcc
      721 cttttcccca gcgtgaggat tctccggacc aagaaacggg aaggcctgat aaggacccga
      781 atgctggggg catcagctgc caccggagat gtcgtcactt tcttagattc acactgtgaa
      841 gccaacgtca actggctccc ccctttgctt gaccgcattg ctcggaaccg gaagaccatc
      901 gtgtgcccaa tgatcgatgt catcgaccac gatgacttcc ggtatgagac tcaggctggg
      961 gacgccatgc gtggtgcctt cgactgggaa atgtattaca aacggatccc aatccctcca
     1021 gagctgcaga aggctgaccc cagtgaccca tttgagtctc ccgtgatggc tggagggttg
     1081 ttcgctgtgg accggaaatg gttctgggag ttgggtggct atgaccctgg cttggagatc
     1141 tggggaggag agcagtatga gatctccttc aaggtgtgga tgtgtggggg ccgcatggag
     1201 gacatcccct gctccagagt gggccacatc tacaggaagt atgtgcccta caaggtccct
     1261 gccggagtca gcctggcccg gaacctgaag cgagtggcag aggtatggat ggatgaatac
     1321 gcagaataca tctaccagcg caggccggag taccgccacc tctcagctgg agatgtcgtg
     1381 gcccagaaaa agctccgagt ctccctcaac tgtaagagct tcaagtggtt tatgaccaaa
     1441 attgcctggg acctgcccaa gttctaccca cccgtggaac ctccggctgc ggcatggggg
     1501 gagattcgca atgtgggcac aggactgtgc acagacacga agcttggcac actgggctcc
     1561 ccactgaggc tcgagacctg catccggggc cgaggcgagg ctgcttggaa cagtatgcag
     1621 gtctttacct tcacctggcg ggaggacatc cggcctggag accctcagca caccaagaag
     1681 ttttgcttcg acgctgtctc ccacaccagc ccagtcaccc tctacgactg ccacagcatg
     1741 aagggcaacc agctgtggaa ataccgcaag gacaagacgc tgtaccaccc tgtgagcggc
     1801 agctgcatgg actgcagcga gagtgaccac agggtcttca tgaacacctg caatccctcc
     1861 tccctcaccc agcagtggct ctttgaacac accaactcga cggtcttaga gaatttcaac
     1921 aagaactgag tccttagacc ttgacaaacc cctcaggttc ctgtggagct cataaacctt
     1981 cctcctgtgg gagaagaggc atcggtgggc accaaggtgc tgggttcttg aaggactgac
     2041 atggtggggc cacggggaga acagaccata ccaatggctc tccaagaagg cggagcctgc
     2101 tcacatcata gcagagctca ccagcctgtc agcatgttcc ctaagtgtta ggaatcgcct
     2161 gggcagcctt gagccatgag gttgcccttg cagacaggac agtgccctag aaaggaaggt
     2221 ggtatcggcc ttgggacagc ttaaacctgt gtgccagctg ctggcaagga agtctgcctg
     2281 ttcttgaggg aactgctaga attgcccagc ttctgtgttg gtccagggca atgagaggcc
     2341 attgggactt ccgagtgctc catagctagc actggccagc aaccaggcga ggggcccctt
     2401 cctctgcagc cagatgtaaa ggatgtctcc cctggctctc tgggtatttc agatgcccgt
     2461 tctagtttca gggctacctg ggcaccaggt cgtcagggct agttcagccg gctaagtaga
     2521 cctccagacc gaacagctcc cagccaatgc ttccaaagcc ctttctccgt gcttttcctt
     2581 ggcggctccc tgccttggag aggaaccggt gctgtgaggg atcacctcca gagtctcctg
     2641 gggggtggct tcccccagat aatgactgct gtggttccaa cctcacagaa ccctggagtt
     2701 tctggaaagt tctgtggttc tgttgaaagc atagatgagc catggcacgt gtgggcatat
     2761 aacgcaagca gccaggtgtc aggcaacccc tgacccaagc agaggcggta gggcaccaga
     2821 agcttcggtc caacccaatg ccgtcacagc cacagcctcg tgaggtgtga ggacatcacc
     2881 tttagcccca tgtctcaaac atgaactcac cctccaagga gctggtcact tgccagtgaa
     2941 gtaactgaga catggtcctg aggccagagc tctgccttag agatgctggg atcggggtca
     3001 tcgggtcccc aggctcgtcg ggttggtgct gtagaaccac ctccacgtag cccctgtgct
     3061 gtcacagctc acttgtggat ttctagtgcc cttttccata tgagcactct gtctgacaag
     3121 tggccggctg ggaaggagtc aaaaagggga gtgggtgggt gtccagaatc cagcagggat
     3181 gcgtgttgca gccaagggga gttgagtcct cagagagcaa tgcggccttg tttcaataaa
     3241 aaccgtgcct tttacaaaga gaaaatgcag ccgagcagct gattccctaa acttgaacca
     3301 cttactagtg ccttgctaga cagacagaca gacagacagg ggagcgtgga gaagggacac
     3361 ttattcgggt cctatgagcc caatgagtgt ctttacgtct gacttcaagc agaaagtgca
     3421 gagcagaacc tgagacccag aggcccccac agcagggaca actgcctatt tgtgcggccc
     3481 tccctgagac aggacagctc tagagacctg acaagcccag aagtgctctg cctgaacctc
     3541 actatcaggg gcgagctgag cagctgggtt tccagcggat gccgagcagg tggttagggt
     3601 ggttaaggca gatgctgccg caagccatcc ctagcctcac tcgctccctt gctcgcccga
     3661 ttcattccat cctcatctgg ttccgtcccc ttctccagca gtcacttcct ctgagcgcac
     3721 ctcagcattt gtgactgctg aactctgacc ttagagccta agacttgagg aggtgtgtca
     3781 caggaagaac caggttggct tggtggctgg ctgcagatac ttaatcccca ccttgtttgg
     3841 gcttcaggtg tggaaatcct tgtcctgaag agtcaggttt ctactctgct gatgggcctg
     3901 tgccacagcc cacgcagcag gccgggcggc tggcctcttc ctccaaagct ttattcagag
     3961 gctaagacta caaaaacaag atgtggttag aaaggcggcc tcccctccgc cccggagatt
     4021 ccagaaacat tttggaatgc agtgtccttg ccatgaggcc attgtgtggc aggcaggctg
     4081 tcttaccctg ccctgccaac tagagcttct ggctttaaaa gcagccagca atgatagatc
     4141 ttgcgttgcg gcagtgagct gctctgatgg gcggcctagt ggatctccaa agtcagcatc
     4201 atgactcccc ttcagtcctt cctgtcacgc tcctccctgc gtggacccct cgcttcagca
     4261 gtccctactt ctcacagagg agactgtctg catccagtgc tcagggcagc ctgtttgtct
     4321 aaagtcaggc agtgtgaaag gaacaaagag tgcaattcca ccctgaattc atcagcactt
     4381 gccgctgagg ctttctccgg caaatcctac tcatattttg gttcaaggtt ttgatgctga
     4441 gccagggccc tgctgccacc attaggtgag agtggtagct acatcccagg tttcaagatc
     4501 ttaacgcggt ccactcagct ctgacaggga gtccaggggc tgcaggcagg gaagctgggc
     4561 actgagacag ggttctgggg gcgggggagg ggcggatccc aagaccaccc acctctcctg
     4621 gaagagagag ccttgtaagg aatgacttat cctgttcagt tgtgactgtg gttgttcaat
     4681 aaacctccag actttctcta aaaaaaaaaa aaaaaaaaaa aaaaa
//
