LOCUS       NM_199366               2846 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus galactose-3-O-sulfotransferase 2 (Gal3st2), mRNA.
ACCESSION   NM_199366 XM_355293
VERSION     NM_199366.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2846)
  AUTHORS   Guerra LN, Suarez C, Soto D, Schiappacasse A, Sapochnik D, Sacca P,
            Piwien-Pilipuk G, Peral B and Calvo JC.
  TITLE     GAL3ST2 from mammary gland epithelial cells affects differentiation
            of 3T3-L1 preadipocytes
  JOURNAL   Clin Transl Oncol 17 (7), 511-520 (2015)
   PUBMED   25532485
  REMARK    GeneRIF: GAL3ST2 interferes with normal differentiation of 3T3-L1
            preadipocytes, leading to decreased triglyceride accumulation
            decreased adipogenic marker expression.
REFERENCE   2  (bases 1 to 2846)
  AUTHORS   Seko A, Sumiya J and Yamashita K.
  TITLE     Porcine, mouse and human galactose 3-O-sulphotransferase-2 enzymes
            have different substrate specificities; the porcine enzyme requires
            basic compounds for its catalytic activity
  JOURNAL   Biochem J 391 (Pt 1), 77-85 (2005)
   PUBMED   15926885
  REMARK    GeneRIF: The substrate specificity and cofactor requirements of
            human, porcine, and murine GAL3ST are reported
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK144526.1, BB871061.1, BC132622.1 and AK165692.1.
            
            [WARNING] On Jan 18, 2024 this sequence was replaced by
            NM_199366.5.
            
            On Mar 12, 2009 this sequence version replaced NM_199366.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144526.1, BC132622.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               AK144526.1         2-227
            227-255             BB871061.1         249-277
            256-1671            BC132622.1         35-1450
            1672-2846           AK165692.1         1676-2850
FEATURES             Location/Qualifiers
     source          1..2846
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 47.38 cM"
     gene            1..2846
                     /gene="Gal3st2"
                     /gene_synonym="Gm988; GP3ST"
                     /note="galactose-3-O-sulfotransferase 2"
                     /db_xref="GeneID:381334"
                     /db_xref="MGI:MGI:2685834"
     exon            1..276
                     /gene="Gal3st2"
                     /gene_synonym="Gm988; GP3ST"
                     /inference="alignment:Splign:2.1.0"
     CDS             251..1441
                     /gene="Gal3st2"
                     /gene_synonym="Gm988; GP3ST"
                     /note="beta-galactose-3-O-sulfotransferase 2; gal-beta-1,
                     3-GalNAc 3'-sulfotransferase 2; gal3ST-2"
                     /codon_start=1
                     /product="galactose-3-O-sulfotransferase 2"
                     /protein_id="NP_955398.3"
                     /db_xref="CCDS:CCDS15197.1"
                     /db_xref="GeneID:381334"
                     /db_xref="MGI:MGI:2685834"
                     /translation="MSILRGTQRSFQVALWFLVLAVFLLVGFLHVDFRLLKPDKVQEP
                     PVTNIMFLKTHKTASSTILNILYRFSESHNLSTALPEGSRVHLGYPWFFVTRYVEGLK
                     QDAHLQHHFNIMCNHLRFNYPEVQKVMPRDTFYFSILRNPVFQLESSFIYYKDYAPAF
                     QRAKSLDEFLADPWKYYNASVSLKNVYAKNNMWFDFGFDNNAPADMDYVRKRLAEVEQ
                     RFHLVLIADYFDESMVLLRRRLRWQLDDVVSFKLNVRSQSTVSHLTPESQERVRHWCA
                     LDWQLYQHFNRTFWTQLHAELSPRQLTEEVEQLRERQRELMALCLQDPEPKNLTHIDD
                     QNLRPYQGGKANILGYNLRHGLDTTTLHICQRMAMPELQHMAHMYSLQFPDKTPKDIP
                     FLKK"
     exon            277..363
                     /gene="Gal3st2"
                     /gene_synonym="Gm988; GP3ST"
                     /inference="alignment:Splign:2.1.0"
     exon            364..622
                     /gene="Gal3st2"
                     /gene_synonym="Gm988; GP3ST"
                     /inference="alignment:Splign:2.1.0"
     exon            623..2846
                     /gene="Gal3st2"
                     /gene_synonym="Gm988; GP3ST"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggattcaac agttaagcta gatcactggt gtgtcctatg tgtgtgtgtg tgttgggatg
       61 gggggtagag ggtggggcat tgggcaccac acctgagcca gtaggtaagc ttcctaggga
      121 tttaagttca gttttcactg aacctatgcc ccatctggca tgctgagaac tggctgtctt
      181 gtagtcaagg aagtggaagg tcttgactgg cacttccctg tccatctcct ggcagctctg
      241 aggcaggata atgtccatcc tgagaggcac acagaggtcc ttccaggtgg cactctggtt
      301 cctggtcctg gctgtgttcc tcctggttgg tttcctgcat gtggacttca gactacttaa
      361 accggacaag gtccaggaac caccggtcac aaacatcatg ttcctcaaga cgcacaagac
      421 agccagcagt acaatcctca acatcctcta ccgcttctca gagtctcaca acctatccac
      481 agcactgccc gagggctcta gagtccatct gggttacccc tggttttttg tgacacggta
      541 tgtggagggc ctgaagcagg acgcccacct gcagcatcac tttaacatca tgtgcaacca
      601 ccttcggttc aactatcctg aggtgcagaa agtcatgccc agggacactt tctacttctc
      661 catcctccgg aacccagttt tccagctgga gtcctccttc atctactata aggactatgc
      721 acctgccttc cagagagcca agagcctgga cgaattcctg gcagatccgt ggaagtacta
      781 caacgctagt gtgagcctga aaaatgtcta tgcgaaaaac aacatgtggt ttgattttgg
      841 ttttgacaac aacgccccag cagacatgga ctatgttcgc aagcgccttg cggaggtgga
      901 gcagcgattc catctggtgc tcattgcaga ctacttcgat gagtctatgg tgctgctgcg
      961 cagaaggctg cgctggcagc tggatgatgt cgtgtccttc aagctgaacg tgcgcagcca
     1021 gagcactgtc tcacacctga cgcctgagag ccaggagcgt gtccggcact ggtgtgcgct
     1081 ggactggcag ctctaccagc atttcaatcg cacgttttgg acccagctgc atgcggagct
     1141 aagcccacgc cagctcacag aagaggtgga gcagctgcgg gagaggcagc gcgagctcat
     1201 ggccctgtgt cttcaggatc cagagcccaa gaacctgaca cacatagatg accagaatct
     1261 gcgtccttac cagggtggga aggccaatat tctgggctac aaccttaggc atggtctgga
     1321 caccaccaca ctgcatatct gtcagagaat ggcgatgccc gagctccagc acatggccca
     1381 tatgtactct ctgcagtttc ccgacaagac tcccaaggat atcccattcc tgaaaaagta
     1441 gggtttggct aagtgaccct ctcttcccag cctacctttc caaagtgaaa ctgtgaagat
     1501 gcccatccgt ctccatctct ggggagaggg ccttccacct aagacaacac gcacagctgt
     1561 tccatatctg aatccaccca ctgtagagac atggacaggc aagaatgctt gtgcccttaa
     1621 attatttcac agagacagtc taagcagccc accaggtgaa catcagccca ggggaacacc
     1681 ggggcataga catcgggcct gtggatccaa gaagagacct agaacggttc cctgggattt
     1741 tgtagccaca ttggttcagc accggtgaca atgccatgct tgtacagggt tcggaggctc
     1801 agaggtaggc cagggagaga cgggatgagt aggcagcctt ccattttacg aagatcagtg
     1861 cagactgaga attgtgaacg ttgttggtta gcctgagcac agacatagtc tactttttag
     1921 cttcctgttg aacagtcctg aaggagaaag tgcctgactt gccacaggtt ctctgagagg
     1981 ctcaggtacc tttggttgtc ttggaaacca tgttgtgtat aatctcaggg atcatctttt
     2041 gggtgcctct cttagtcatt catggagaga tactaagtat ctagcaccca gctctcagga
     2101 tgaggtacct gattccctgg gttactcaaa cagggtgcct gaggtgttgg gaaaagaagt
     2161 cactgtcaca tacacagcct ttcttcctga gccttgctca ctgagttttg gtggaggctt
     2221 ttcttctgtg tcagatgtct cagaaaagac agaccatgct cctttgtacc tcaatttaat
     2281 atggacatca attcaatatg aaaagtaatt gtcaaagaaa aagtaattgt tggtgagttt
     2341 agagatggta caatggtaca atgagtttgt caatccaaaa gaacactgta aattgagaat
     2401 tgactctccc aaactgaaca gaggtattca gaatgctaga gagatgctgg ctcagccctt
     2461 ttaccctagc actggggagg tagaggcaaa cagatctctg agtttaaggc cggcctggac
     2521 tacatagtga gttccacgac aaccaggtta caaagtaaga gaccctgctt caaaacaaaa
     2581 cagaaaacca ctgaagcccc ccagccttga gcaggctggc tcagacctgt tctgccactg
     2641 tgaacaagac cacctagggt ggagtctcct gatctagata ggtctattgt tctgccacct
     2701 ctgtttcctc caagatgcca ctacctgctg agaggctgaa ccagttctcc tgacactatc
     2761 cagatgaaag gagatcctgg cctggtgggg gatgggatgc ccctctttat aagctcagat
     2821 tcttaagtaa actttgggcc ttgatc
//
