LOCUS       NM_146017               3280 bp    mRNA    linear   ROD 16-JUN-2024
DEFINITION  Mus musculus gamma-aminobutyric acid type A receptor subunit pi
            (Gabrp), mRNA.
ACCESSION   NM_146017
VERSION     NM_146017.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Wu,L., Belyaeva,O.V., Adams,M.K., Klyuyeva,A.V., Lee,S.A.,
            Goggans,K.R., Kesterson,R.A., Popov,K.M. and Kedishvili,N.Y.
  TITLE     Mice lacking the epidermal retinol dehydrogenases SDR16C5 and
            SDR16C6 display accelerated hair growth and enlarged meibomian
            glands
  JOURNAL   J Biol Chem 294 (45), 17060-17074 (2019)
   PUBMED   31562240
REFERENCE   2  (bases 1 to 3280)
  AUTHORS   Hooper,J.E., Feng,W., Li,H., Leach,S.M., Phang,T., Siska,C.,
            Jones,K.L., Spritz,R.A., Hunter,L.E. and Williams,T.
  TITLE     Systems biology of facial development: contributions of ectoderm
            and mesenchyme
  JOURNAL   Dev Biol 426 (1), 97-114 (2017)
   PUBMED   28363736
REFERENCE   3  (bases 1 to 3280)
  AUTHORS   Mo,J., Kim,C.H., Lee,D., Sun,W., Lee,H.W. and Kim,H.
  TITLE     Early growth response 1 (Egr-1) directly regulates GABAA receptor
            alpha2, alpha4, and theta; subunits in the hippocampus
  JOURNAL   J Neurochem 133 (4), 489-500 (2015)
   PUBMED   25708312
REFERENCE   4  (bases 1 to 3280)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 3280)
  AUTHORS   Rosas-Arellano,A., Machuca-Parra,A.I., Reyes-Haro,D., Miledi,R. and
            Martinez-Torres,A.
  TITLE     Expression of GABArho receptors in the neostriatum: localization in
            aspiny, medium spiny neurons and GFAP-positive cells
  JOURNAL   J Neurochem 122 (5), 900-910 (2012)
   PUBMED   22168837
  REMARK    GeneRIF: This study demonistrated that GABArho receptors expression
            in in aspiny, medium spiny neurons and GFAP-positive cells in the
            neostriatum.
REFERENCE   6  (bases 1 to 3280)
  AUTHORS   Guo,Z., Zhao,C., Huang,M., Huang,T., Fan,M., Xie,Z., Chen,Y.,
            Zhao,X., Xia,G., Geng,J. and Cheng,L.
  TITLE     Tlx1/3 and Ptf1a control the expression of distinct sets of
            transmitter and peptide receptor genes in the developing dorsal
            spinal cord
  JOURNAL   J Neurosci 32 (25), 8509-8520 (2012)
   PUBMED   22723691
REFERENCE   7  (bases 1 to 3280)
  AUTHORS   Andang,M., Hjerling-Leffler,J., Moliner,A., Lundgren,T.K.,
            Castelo-Branco,G., Nanou,E., Pozas,E., Bryja,V., Halliez,S.,
            Nishimaru,H., Wilbertz,J., Arenas,E., Koltzenburg,M., Charnay,P.,
            El Manira,A., Ibanez,C.F. and Ernfors,P.
  TITLE     Histone H2AX-dependent GABA(A) receptor regulation of stem cell
            proliferation
  JOURNAL   Nature 451 (7177), 460-464 (2008)
   PUBMED   18185516
REFERENCE   8  (bases 1 to 3280)
  AUTHORS   Hood,H.M., Metten,P., Crabbe,J.C. and Buck,K.J.
  TITLE     Fine mapping of a sedative-hypnotic drug withdrawal locus on mouse
            chromosome 11
  JOURNAL   Genes Brain Behav 5 (1), 1-10 (2006)
   PUBMED   16436183
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL669814.16.
            
            On Nov 17, 2006 this sequence version replaced NM_146017.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028946.1, BC031196.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-152               AL669814.16        100336-100487       c
            153-251             AL669814.16        94848-94946         c
            252-370             AL669814.16        93903-94021         c
            371-438             AL669814.16        89597-89664         c
            439-656             AL669814.16        88743-88960         c
            657-739             AL669814.16        85396-85478         c
            740-877             AL669814.16        78460-78597         c
            878-1030            AL669814.16        76498-76650         c
            1031-1218           AL669814.16        75824-76011         c
            1219-3280           AL669814.16        72311-74372         c
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 19.21 cM"
     gene            1..3280
                     /gene="Gabrp"
                     /note="gamma-aminobutyric acid type A receptor subunit pi"
                     /db_xref="GeneID:216643"
                     /db_xref="MGI:MGI:2387597"
     exon            1..152
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            153..251
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            252..370
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            371..438
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            439..656
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            657..739
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            740..877
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1030
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1218
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..3280
                     /gene="Gabrp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3183..3188
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gabrp"
                     /note="hexamer: AATAAA"
     polyA_site      3204
                     /gene="Gabrp"
                     /note="major polyA site"
ORIGIN      
        1 gagagagcgc gccactccat cggagactgg gtgcatactt aacacccaaa gagtcaggac
       61 tgagatgaaa aggaccctgg agacccaaaa gagtatgctc tgtgtgagag tcctgcctga
      121 gatctggaaa cacctgctgt aacagctgcc tggtgattcc tccttcaacc tttttgtgtg
      181 tgaatcagct ccttcaacat gagctacagc ctctatttgg ccttcctgtg tctgagtctc
      241 ctcactcaga ggacgtgcat ccaggggaac caggtcaatg tggaggtcag cagaagtgac
      301 aagctttcct tacctggctt tgagaacctc actgcaggat ataacaaatt cctcaggccc
      361 aatttcggtg gtgacccagt tcggatagca ctgactctgg acatcgccag catctctagc
      421 atctcagaga gtaacatgga ctacacagcc actatatacc tccggcagcg ttggacagac
      481 ccacggctag tgttcgaagg caacaagagc tttactctag atgcccgcct tgtggagttc
      541 ctctgggtgc cagacactta cattgtagag tccaagaagt ccttcctcca tgaagtcaca
      601 gtgggaaaca ggctcatccg cctcttctcc aacggcacag tcctgtacgc acttagaatc
      661 acaacaacag ttacatgtaa catggatctg tctaaatacc ccatggacac acagacctgc
      721 aagctgcagc tagaaagttg gggatacgat ggcaatgatg tggagttctc ctggctgaga
      781 gggaatgact cggtgcgtgg acttgaaaac ctgcgccttg ctcagtacac aatccaacag
      841 tatttcaccc tggtcaccgt atcccagcag gagacaggaa actatacgag attggttttg
      901 caatttgagc ttcggaggaa cgtcctgtat ttcattctgg aaacctatgt cccttccacc
      961 ttcctggtgg tgttatcctg ggtctccttt tggatctccc tcgattcagt tcctgcgaga
     1021 acctgcattg gagtgacaac ggtgttatcc atgacaacgc tgatgatcgg ctcccgcaca
     1081 tccctaccca acaccaactg cttcataaag gccatcgatg tgtacctagg catctgcttc
     1141 agcttcgtgt ttggggcctt actggagtat gcagttgctc actacagctc cttacagcag
     1201 atggcagtca aagatagggg gccagcgaag gactcggaag aagtcaatat caccaacatc
     1261 atcaacagct ccatctccag ctttaaacgg aagattagct ttgccagcat tgaaatctct
     1321 ggtgacaatg tcaactatag tgacttgaca atgaaagcca gcgacaagtt taagtttgtc
     1381 ttccgagaga agatcagcag aatcattgat tatttcacaa ttcaaaaccc cagcaatgtg
     1441 gatcgatact ccaaactact atttcctttg atttttatgt tggccaatgt attttactgg
     1501 gcatactaca tgtatttttg agacgccatt gaactcttgc atcacataat gaggttaagg
     1561 gtattctaga acatgtgtgt gcacttcagc ttagaaagct acaaatgggc taatgtaaca
     1621 attattctaa gttgtgtaga agccctagtg tgaccagatt ctataataga gtcattataa
     1681 ggcaaccctt ttcttcttca attttggaca gaacaccccc tccacacaca tacacagaac
     1741 ccaagactgc gaacctactc agggctattt gctctctgga tccctggtct gcattcactc
     1801 cataaaaatg tgggaagatg attacatata ttaaggggtt tattttctaa agaattcata
     1861 gtgccactga ttacatctct gtggccctta taatatgctc tcttgcctat ttaaacacca
     1921 gtgttttcta atttttgttt ttccttgaaa tatgaaatgt gggtttgcgt caattcattg
     1981 gtggttacct tgcctcatca acctaatacc agatgggttc ttagtgttat ttaataccac
     2041 agaagaattg tccccaaatt ctaatacatc ctattattca caaatcagat gtaaatgaat
     2101 aaaattagtg gatcaataaa ctaaaagaaa aaaacataaa tcctttgggg tccagggctt
     2161 catgccgttt ttccacgtat cttattattt tgtttttata caccttagtc ctaacctatg
     2221 taaaaacccc ttttccacat caggaaaacg ggaggaagtt ttgaaacttg ttctggattc
     2281 ctaatacaga atgcgtccat gaagacttgc tgagtcaagt gtactagcta gccaccttta
     2341 ctcacatact ggctaggaac caagtagacc agagagtgct ctgtcaacct gtcctctctg
     2401 ctgacctgtt gaccaagatg ctggggaaca ttttgccggt ggcaaaggcc ctgcctcctt
     2461 caaagaggag cttttatccc tgtgctccag tgactaggca ggagtgatgt ctattagata
     2521 agaagcggca ctactgggac acaagtagct tatcttaaat agttaccttt tcccaacctt
     2581 tctagctgga ctactttgag tggattaccc tgcctgagca gcagaccact ggccctgact
     2641 ggttccgact gttctgaacg atggaaagac acattgcaca acccacgtga gctgtctttt
     2701 ctgagttcag ccagggtcac cctgacctag gagctcttgt gtgccctctc tctctcttgc
     2761 tccacgggaa tcgcctatat aaggttccaa tgcagcctca attgtttcaa agactcttgc
     2821 tgtcttcagg tctttccctt ccttttctaa tgaaccctca gctttccctg tcctttctac
     2881 aacaaaccgg ggctgtagat gttctttcct ttcacgtcct tcacccacgg gccctccttt
     2941 tcatcagcat ggctctgccc atcgttccgt ttctgtgagc ttgagtgcct ggcgcttaac
     3001 agatgtttct attttaggat tcgctttgtt cattggagta caataggtgt agttgcgcca
     3061 ttagagttct tagtagaatc tctttgtatt ttgtatctgt catatacatt cctaagggga
     3121 ggggctaggg gaggggaagt gtggttgagt gagtaggtca tacctgtgca ttttttttta
     3181 aaaataaaaa tgtttaaaat ataacttcac tgaggcctca ttttaagcta cagaaaaata
     3241 aaagttgtaa atatgtgaaa ctataaaata aatatatagt
//
