LOCUS       NM_008074               9796 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus gamma-aminobutyric acid type A receptor, subunit gamma
            3 (Gabrg3), mRNA.
ACCESSION   NM_008074
VERSION     NM_008074.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9796)
  AUTHORS   Neumann,E., Cramer,T., Acuna,M.A., Scheurer,L., Beccarini,C.,
            Luscher,B., Wildner,H. and Zeilhofer,H.U.
  TITLE     gamma1 GABAA Receptors in Spinal Nociceptive Circuits
  JOURNAL   J Neurosci 44 (41), e0591242024 (2024)
   PUBMED   39137998
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9796)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 9796)
  AUTHORS   Niewiadomska-Cimicka,A., Krzyzosiak,A., Ye,T.,
            Podlesny-Drabiniok,A., Dembele,D., Dolle,P. and Krezel,W.
  TITLE     Genome-wide Analysis of RARbeta Transcriptional Targets in Mouse
            Striatum Links Retinoic Acid Signaling with Huntington's Disease
            and Other Neurodegenerative Disorders
  JOURNAL   Mol Neurobiol 54 (5), 3859-3878 (2017)
   PUBMED   27405468
REFERENCE   4  (bases 1 to 9796)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 9796)
  AUTHORS   Kwakowsky,A., Schwirtlich,M., Kooy,F., Abraham,I., Mate,Z.,
            Katarova,Z. and Szabo,G.
  TITLE     GABA neurotransmitter signaling in the developing mouse lens:
            dynamic regulation of components and functionality
  JOURNAL   Dev Dyn 237 (12), 3830-3841 (2008)
   PUBMED   18985723
REFERENCE   6  (bases 1 to 9796)
  AUTHORS   Baer,K., Essrich,C., Benson,J.A., Benke,D., Bluethmann,H.,
            Fritschy,J.M. and Luscher,B.
  TITLE     Postsynaptic clustering of gamma-aminobutyric acid type A receptors
            by the gamma3 subunit in vivo
  JOURNAL   Proc Natl Acad Sci U S A 96 (22), 12860-12865 (1999)
   PUBMED   10536013
REFERENCE   7  (bases 1 to 9796)
  AUTHORS   Greger,V., Knoll,J.H., Woolf,E., Glatt,K., Tyndale,R.F.,
            DeLorey,T.M., Olsen,R.W., Tobin,A.J., Sikela,J.M., Nakatsu,Y. et
            al.
  TITLE     The gamma-aminobutyric acid receptor gamma 3 subunit gene (GABRG3)
            is tightly linked to the alpha 5 subunit gene (GABRA5) on human
            chromosome 15q11-q13 and is transcribed in the same orientation
  JOURNAL   Genomics 26 (2), 258-264 (1995)
   PUBMED   7601451
REFERENCE   8  (bases 1 to 9796)
  AUTHORS   Culiat,C.T., Stubbs,L.J., Montgomery,C.S., Russell,L.B. and
            Rinchik,E.M.
  TITLE     Phenotypic consequences of deletion of the gamma 3, alpha 5, or
            beta 3 subunit of the type A gamma-aminobutyric acid receptor in
            mice
  JOURNAL   Proc Natl Acad Sci U S A 91 (7), 2815-2818 (1994)
   PUBMED   8146195
REFERENCE   9  (bases 1 to 9796)
  AUTHORS   Wilson-Shaw,D., Robinson,M., Gambarana,C., Siegel,R.E. and
            Sikela,J.M.
  TITLE     A novel gamma subunit of the GABAA receptor identified using the
            polymerase chain reaction
  JOURNAL   FEBS Lett 284 (2), 211-215 (1991)
   PUBMED   1647983
REFERENCE   10 (bases 1 to 9796)
  AUTHORS   Sulpizio,A., Fowler,P.J. and Macko,E.
  TITLE     Antagonism of fenfluramine-induced hyperthermia: a measure of
            central serotonin inhibition
  JOURNAL   Life Sci 22 (16), 1439-1446 (1978)
   PUBMED   27681
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102129.9, AK046263.1, AC116146.14 and AC102098.8.
            
            On Jun 3, 2018 this sequence version replaced NM_008074.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.124795.1, X59300.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-344               AC102129.9         56482-56825
            345-712             AK046263.1         2-369
            713-933             AC116146.14        49733-49953
            934-1016            AC116146.14        52189-52271
            1017-1154           AC102098.8         159383-159520       c
            1155-1307           AC102098.8         121093-121245       c
            1308-1504           AC102098.8         115737-115933       c
            1505-1564           AC102098.8         115423-115482       c
            1565-9796           AC102098.8         102609-110840       c
FEATURES             Location/Qualifiers
     source          1..9796
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 33.48 cM"
     gene            1..9796
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /note="gamma-aminobutyric acid type A receptor, subunit
                     gamma 3"
                     /db_xref="GeneID:14407"
                     /db_xref="MGI:MGI:95624"
     exon            1..495
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             443..1846
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /note="gamma-aminobutyric acid receptor subunit gamma-3;
                     GABAAR subunit gamma-3; gamma-aminobutyric acid (GABA) A
                     receptor, subunit gamma 3"
                     /codon_start=1
                     /product="gamma-aminobutyric acid receptor subunit gamma-3
                     precursor"
                     /protein_id="NP_032100.2"
                     /db_xref="CCDS:CCDS21320.1"
                     /db_xref="GeneID:14407"
                     /db_xref="MGI:MGI:95624"
                     /translation="MAAKLLLLLCLFSGLHARSRRVEEDENEDSPSNQKWVLAPKSQD
                     TDVTLILNKLLREYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTW
                     TDSRLRFNSTMKILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKIL
                     YTLRLTINAECQLQLHNFPMDAHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRL
                     YQFDFMGLRNTTEIVTTSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFW
                     IKKDATPARTTLGITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEY
                     ATLNYYSSCRKPTIRKKKTSLLHPDSTRWIPDRISLQAPSNYSLLDMRPPPPVMITLN
                     NSMYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRRGRIHIDVSELDSYSRVFFP
                     TSFLLFNLVYWVGYLYL"
     exon            496..644
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            645..712
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            713..933
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1016
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1154
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1307
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..1504
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1564
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..9796
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9771..9776
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /note="hexamer: AATAAA"
     polyA_site      9794
                     /gene="Gabrg3"
                     /gene_synonym="6330406O05Rik; B230362M20Rik; Gabrg-3"
                     /note="major polyA site"
ORIGIN      
        1 cccgacctcc caactccgag tccattcaaa cctcgctgcc ttcgcctggc attgccaagc
       61 gtgttaattg gggaaactcc tccccgccgc ggccggcggg caccaccgag gcaaccgcga
      121 cctcccgcca cgcttcggag cgcagctgcc ccagcgcaga gccccgagcc ggcccgggag
      181 gtggggggct cgggctgcgg gaggagggtg cccggccacc tgctgccccc ccttccccgt
      241 gctgatcgct cccgagagcg gacgcacccc agctcgtgtg cgccccgcag agccggaccg
      301 tcggggacgc ggcgctcgga gcagacacct gtccctccca gtccgcagaa ccctgggcgc
      361 tgcagcccgt gggagtctag taggcgccgg agcaagtaga gaccaagccc tgcagaggcc
      421 tcggacccgc tcccggagag ccatggctgc aaagctgctg cttctcctct gcctgttctc
      481 gggcttgcat gctcggtcca ggagggtaga agaagatgag aatgaagact ccccatcaaa
      541 ccagaagtgg gtcttggcac ccaaatcaca agacaccgat gtaacgctga ttctcaacaa
      601 attgttgaga gaatatgaca aaaagctgag accggacatt ggaataaaac caactgtgat
      661 cgatgtggac atttatgtta acagcattgg tcctgtgtca tccataaaca tggaatacca
      721 aattgatata ttttttgctc aaacctggac agacagtcgc cttcgattca acagcacaat
      781 gaaaatacta actctgaaca gcaacatggt gggcttgata tggattccag acaccatctt
      841 tcgaaattct aaaacagcgg aggctcactg gatcaccaca cccaaccagc tcctcagaat
      901 ctggaatgat gggaaaatcc tttacacatt aaggctcact atcaatgcag agtgccagct
      961 gcaactgcat aacttcccta tggatgcgca tgcctgcccc ttgaccttct ctagctatgg
     1021 ctaccccaaa gaagaaatga tttatcgttg gaggaaaaat tcagttgagg cagctgatca
     1081 gaaatcatgg cggctctatc agtttgactt catgggcctc agaaacacta cagaaatcgt
     1141 gacaacatct gcaggtgatt atgttgtcat gactatctat tttgaactga gtcgaagaat
     1201 gggatacttc acgatccaga cgtatatccc ctgcatactg actgtggttc tgtcctgggt
     1261 gtcattttgg ataaaaaagg atgcgacacc agcaagaaca acattaggca tcaccacggt
     1321 gctaaccatg accacactca gcaccattgc caggaagtct ctgcctcggg tgtcctatgt
     1381 cactgccatg gacctctttg tgactgtgtg cttcttgttt gtctttgccg cactgatgga
     1441 gtatgctaca ctcaactact attcaagctg tcgaaagcca accatcagga agaaaaaaac
     1501 atcgttatta catccagatt ccacaagatg gattcctgat cgaataagcc ttcaagcacc
     1561 ctctaattac tctctactgg acatgaggcc cccaccacct gtgatgatca cgttaaacaa
     1621 ttccatgtac tggcaggaat ttgaggacac ctgtgtctat gagtgtctgg atggcaaaga
     1681 ctgccagagc ttcttctgct gctatgagga gtgcaagtct ggctcctgga ggagaggccg
     1741 catccacatt gatgtctctg agctggactc ctactctcgg gtcttcttcc cgacatcctt
     1801 cctgctgttc aacctggtct attgggttgg atacctgtat ctttaagtgc tgctctgagg
     1861 gatgactgaa gagtacttga ttcatgtgtt tctttccact gtccccagac aagtagtgat
     1921 caaccaaaaa agagtagcag ggaaggacat gactccagtt tgttgtgcta cctttcagca
     1981 gcttgggaag tactggaaag tattccttat aaatatttca ctcacacaca ctcactcaca
     2041 tgtgcacaca cacacacaca cacacacaca cacacacaaa gaggaactgc atcttcaaag
     2101 tgatattctt gctaatccct tcttcaaccc atagtttgat atatatgaat ggccttggat
     2161 acagaagctg ccagttatca tgcaacgacc cctgtgaaag atgcaaacca atatctagac
     2221 attgtctcag atcctcccca ttgtgtatct tccttttgca tcgcttggga ccagtgcccg
     2281 tacacacagg atctacctta gtggagatac actcatggtg acctctctga gattcagttt
     2341 gaagtgcagt cagttttggc cccttctgtg aggcctgttt gctcagacac tgaagtccta
     2401 ggctaacctc tctctaactg gcactcttct ttcctgcctg ggaggtatat aagccacaag
     2461 tttccattca tgggaaaaaa atgtgatttt taaaaattgt tcctgagacc aagactgctg
     2521 tttgtctcta actctaacaa agtcgtgact ttattgcaga ctgccaagca tcagccatat
     2581 tggcatcctg ggttcctgga ccagttgcat ttgaatccag catttttcaa agagctgcga
     2641 tttataagac caagtctcag tctcagatga tgagggtagc ttatattatg ttagggattc
     2701 ggtaactgtc ttcaccctgc aaacacatgc aatgtggata ggcctttgtt tggaagcggc
     2761 gttctacagt gtaaaataac ataaacatcc atgtatttaa tcatgagcat taacttcaaa
     2821 gccaaaccaa ctttagatcc caaaattggt gatggttatt gtcaattaca cattttgatg
     2881 aacacaattt gttttatact ttgaaatatg aatgcatagc aaaatcccaa agaaaccccc
     2941 caaaatcaat tctcttttga tatttttata acacaaaaca aatttgcttc ttcatattag
     3001 ttatttgcta tgaccagatg ctcttgtgca ctccaagtct tgtgcactcc atgactcttt
     3061 tgaagcatcc tctattggtg acaaccacac atttccactc attagcaggg tcttggcact
     3121 gttatggcat ccacagtaca atcctggtgt gcttttatcc cacaaagctg aattaatttt
     3181 attgaaagtc attcttattt ttccacttct attacacata ctatatcact acttagaaaa
     3241 agtaaaacat cagacaaata gaatatatca aagtgctgac ttcacacaat ttattagatg
     3301 tatttctgaa acgatgatgg tattgaagag accggaaaac tgaaagtaga tacttttgct
     3361 aattctttct agtactgttg cactagatga agtagatgtg aaaacggaca cacctctcat
     3421 ttgtaagggt aataatggct gtctgtgtgt ttgtgtgtga tattcagtct tttctttctg
     3481 agtttcaact aacaaactac tagtttgata gttaccacat aaggctcaag tcaactggct
     3541 tctagttaga aaattcaatt taaaagaatt aaaataataa atgtccataa agaataagct
     3601 gaaataatgg cttagatgaa atgtctcctc tgttgggagg ttttgcatct agtgctctag
     3661 tgtctctgaa gctccagcct ttggcaggcc cactctgaag gtgcccacaa cactgaagac
     3721 agagagcaag ccacacacac aattgcaaac actgtcagct cagaattgct aatcagataa
     3781 agaactttaa tctgttacat tttaaaagtt ctggggagaa ctaaattttc tagtcatctt
     3841 tttgttttca aggattaaaa tctgtaagca tgtgctatag ggatggactc cctgctacct
     3901 tagacaaacc ccacagttgc ctcttatctc aaaacttgtc attgtcattg tctcttgccc
     3961 aacctcagcc atgctgatca aaacatagga agagccaaca cacatgtcac gagtatgcca
     4021 atgcctgttt ctcagtaaag ttcaattgtc tatgtcagtc tgaaatccca ggataaccca
     4081 ttctggtaca tgaaacggga gagatgcctg cccattgctc aggggcaaaa ccaggggctt
     4141 tataaggtga actctgagga gagtctggta cacttggagg agagggagag atgcacccct
     4201 ccttagacac cagctcccct tagttaatta agagggacat gtgtgggcac acaaactcaa
     4261 gcctcctcta acctgcccca ttctgctttg tttccttcgt gtgaagatct ggggaattgc
     4321 ttgggtggtg gtctgaacaa ccttcatttc aaaggtgcta ctgtgttcct cactcttaga
     4381 agcactccag actgaggaga ctatttgaac agattcccaa accactgtgg attatacgga
     4441 aaactgtgac tgtctctccc ttaaactaca tcctgattga tggagaaaac ctaaaaagat
     4501 gttttaaaaa gtagtaaaat tcaagaaaaa tgcctcttca aagcctagac agattcccta
     4561 gggtatccta gatgctaggt ggaggacagt gttaataaat taactctgag tccagctaac
     4621 actgcctcca gtttgcccaa aatatgcctt aaaataaaac ataaagcccc caaattttac
     4681 atttctggaa atttcaactt cctgtagtcc ccctttttca tactaaattt tgcttttttt
     4741 aaaaaaatat aataggattt catttctttc tatgacaacc aggcatttcc atgtttgcat
     4801 cagatgagat aaaattacag actttcatgg aatcttcaaa catggaaatg ctggtcctta
     4861 atcacaagct attctcatgt agaaacctgt gggtttatgt ccacaaatca gcatcattcc
     4921 agactgtttt acctggtaat atgttgctgc agttaaagat gtttagatgc gtgttgtagc
     4981 cctacacaat gccacatctg gaaacagtag aagcaagcca cctgaactga atcccattcc
     5041 acatcaattt gtcttgacac agctaggaag cagaggtcca ctctatccaa agggctagga
     5101 aaaaaaaaaa caaaacaaca gacaccacct ctgcctcctt ggtcattttt atctcacatg
     5161 ccaaactgaa atttttattc agaacttgga gaattgtgac tggtccccgg atgttgcacc
     5221 cccattctat cacttcagag ccctggcggc atcaggcttc ttgaatctgt ttgtggtttg
     5281 acaactattt tttcgtgctt tccttttaga gttaaaaatc atgcaagtgt tcattttgaa
     5341 aagaataaaa tgatgagaga taaacatagt atataaataa gtatacattg aaatgttgaa
     5401 tttcatttat accgatagat tattggtttg gaactttaga acacaatgat atggaaaggt
     5461 ctttggaaat aggaaggcag caaacagaat accaattcac agaaaaatgt cttattcaca
     5521 gttttccctg agctcctgtc aaatggcgac tagtggcctg tgataaccag tgggtctaag
     5581 actaatcgtg gtccaagaac tgaatgctaa tgaagtgctc aggacagaca ggcccatctc
     5641 tgatctccct tctattgtaa acatggatca aaacataaca gggagagaaa acaacccgtg
     5701 tcttgagatg ataaggtaac agctaacaca gacaccttcc cagaataaga agttgttttg
     5761 ttttttaaaa tatattacag ttttggagcc ttgaagttgg gatgtttcaa cttccctctt
     5821 ttaaaatttc tttagcttac aagatactaa tcccatgata aaagcttgat ttaattctgt
     5881 taaggttaaa agagaagatg tttctattcg tttgcttcca agatgtcttt tagttgagtg
     5941 gtgcttttgt tctaatattc cctgtaagac ttctaaactt ctttgttact tttcctagaa
     6001 taaaatccca gtcttaaaaa cagcttacat aaatcagcac aaaactctga cttgaactct
     6061 cgttggtcat tagaaagttt cccatgcttt gagttaacca ggttaggtta tgtgaactag
     6121 aatacttaca cacacacaca cacacacacg cacacacaca cacacacaca cacaccactt
     6181 ccaaattaag gaaagtctga tttttttttt cattttaatt gagacaaatg taaactgctt
     6241 tgcttaacct gttgagttaa gcatctattt caagcacttc atttttcata tctgtaagca
     6301 cagtacaagg ttgtcccagc ccagggaaca ggttgcacag ggtgagtcaa tagtagttac
     6361 tgtgggaaag gaaggcttct ctgtctgaaa ggtagtttaa gctgaaaggg tagggagaaa
     6421 caattgactt tcaacaacaa aacctcccaa actgagctag ttcctgcttt gttttgttct
     6481 tttctagata tttaaagata cttctctgta tttctctgaa caagtacagt cggcttctgg
     6541 atccatgtat tctgtatctg tgatttcaac caccatcaag aatgccaacc acttttgtct
     6601 ctgtacctag cgtgggcagg catttctcct tgtgattatt tctctaaata taagagtgta
     6661 acgacagaga ctgacataga atgtacaatg cattaagcag tgtaagctgt cctgtggtgg
     6721 tggaatgtat agagaagaat gtgcatagtg tctatgcaca taatgcccca ctttattcaa
     6781 aggatctgtg catctgagag ttctgttttc ctgagggatc ctggaatcag cacccccccc
     6841 gcccccccgc aaatttggag aagtgactac aatgttttca tttcttatga cggacttaga
     6901 tcctgatgtc tcctggctgc cctgcccact gaagtaccat gtcagtacat ttacataacc
     6961 aagccagtgt tcatttctta aatatgcatt tcttagatca ggtgctcaca acatggctat
     7021 tacagtcccc tctatacatc ttaaaattat gatattgtcc ctagcttcca ttcacaaaag
     7081 atagttccca tttaccatta atcattgatc atttttgaat acataggact ttatatagtg
     7141 gactctcaaa tcacactagg gaaaaaaatg tttgacccta agctgtagct ttatgaacat
     7201 tgtgagaatc aatgtggaag cttaagatgt caggcatgtg ctgaagtaag ggtgacatgg
     7261 gtccaccttc tgattttctc ctcaaacagg ctgagttctt aatgtgtgaa tgagtctgct
     7321 tcctggcaca gcgaggcgag tgcttctggt agggttgtgc ttgcacctac tgaacaatct
     7381 cccaggacag ctggctggat aggcaatcat aaatgtcctt gtcagttgta gtgagagtgc
     7441 ccacaacttg cctacatcat tttcttaaac atcaagttat gccccggttc acaggaatct
     7501 tctggaaaga ttctcaagac atattttaga agtcttccca ttgtagaatt ggtattgtca
     7561 gggacaagta ataacagctt tgaaataatt agtatttgct gaaatgtctt tttatcaata
     7621 attgtccagg cttttaacag gaaggattct tatcaatttt gtgtgaaggc ccccaacaca
     7681 cagaacccca cactgagaag acctaactgc ccaaccctct gtctaacctt ggcagtcaca
     7741 ggtaaccatc agtgaactgg acacatcatt gtgtccttgc attttcaggg ttatctggga
     7801 aaataaaaat aaagaacaaa aaaaaaagct aagaaacaaa tcctatcttc ttaagtaaca
     7861 ttctctgtaa ttaaaagcag aaaatgtaca taaccttgat gactgaactt tccaacgtac
     7921 ccatcagata tgaaggaaga gtatggcaag acctccgtca tggtttttgt ccatggtcta
     7981 gtttgtagcc accaaagcag tgcagagatt ttctgtcttt tataagctgt gaaaaaatta
     8041 ggatgtgtgt ggtttttttt ttttttaatg atgacaagct cttaaaactt taattgtaat
     8101 gttagaatag agtccaaatt tttgttcatt ccttggaagt ccatctgccc tggttccaga
     8161 gtttcccagc atttgaggaa tgcatgccac ccagtattta tttcctggtt actttcttct
     8221 tttcattctt gccttattgg acacttttag tcgttttctt ctagatacat ttttgattgg
     8281 ctaggcacta ttttttctaa tgtggctgca tcttcagaag ttgtaagttt tgttgcccaa
     8341 agaaaccatc actcctttgc tctccgtgtc tttgggtcta ggagttactg cagatcttgt
     8401 tggcattttt ttttttacta tagtctctct aactatatag tagtgaagtg tttgctattg
     8461 ttttcctttt ttcagcttag agtaatgatg gaaacacccc caaaggcaca atggccagtt
     8521 gtgctggtga gccacgttta catactgaca aatttgtcta cagatacatg ttttcttaag
     8581 cagctcctgg actcagcaaa gctttgcttg tttgtgtttt ccatgaaagg ctctaggaga
     8641 gtgacaattt tcagggactg acctgtatct tgtttgaagt gatggggtat cgtgtgttta
     8701 catgcagtga tgtgtgtttt tgtgtttgtg tgtaccgcgg taaaactgaa caacctatta
     8761 atgtgtgcgt tactctatca actgccccaa atttagttga aacacttagg agcacagctt
     8821 cctagtgata gcatgttagc ttagtaagcc tctggttaag gcaaacggga aacaggggga
     8881 agaagggaaa aggaagagaa gggcccagat agagtaagag acaatcattg tatttcccca
     8941 aaatatggga tcacatgctt taaaaaaaca aatcaagatg agatgcctga tcagaagctg
     9001 gcatggagaa catgtaagca ccaccaagtt tcttgggtgc cttgattatc tgtgtactgt
     9061 gaccaggctt atctgatata ctgatagtac ttcttgatag ttatatggta cactggcctt
     9121 gcagtgttta tttgggaagc catgtagttg ttcatagata tacctaggta gggcctggcg
     9181 tgaattttca aagcctagga gtcagctaca gagtatgcag gttcattctg cgaagtaaaa
     9241 ctttcacagt cctgggccgt gactcaggca aaaaaagtat gagattgatt ttctatctgc
     9301 ctggagtcct tcccacctct acagcctaag gtaggctgat tccagaatcc cacagcattt
     9361 tgatagcagt tctgagcaag tgaggactgt agagggcatt ggctgggagg agggtgacct
     9421 gtcctgtcca agctggctgg ccccttagag aactgggatc atggtcagag gctggcctca
     9481 caccagtggc ttgcaagagc actggatgtc ctgctgtcct cgagggccct cttccccagc
     9541 ataaaaaaac ggtgactccc ctgtaccctg caactcgtgg tgtcctagtg aagagagggc
     9601 gcccttgtgc ccaacgtgcc ttggcgaccc cggcggcacc gcgccctgcc ttgcacgtcg
     9661 cgaccccgcc gagccctcag ggccaaaccc agccagaagc cacctgagcc ttgtggctgg
     9721 gccgccctct gtatttgtat ttggattcct atgtttgtac ttctgataca aataaatgca
     9781 catgttgtca gaaata
//
