LOCUS       NM_001081141            5578 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus gamma-aminobutyric acid type B receptor subunit 2
            (Gabbr2), mRNA.
ACCESSION   NM_001081141 XM_143750
VERSION     NM_001081141.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5578)
  AUTHORS   Hamad,M.I.K., Jbara,A., Rabaya,O., Petrova,P., Daoud,S.,
            Melliti,N., Meseke,M., Lutz,D., Petrasch-Parwez,E.,
            Schwitalla,J.C., Mark,M.D., Herlitze,S., Reiss,G., Herz,J. and
            Forster,E.
  TITLE     Reelin signaling modulates GABAB receptor function in the neocortex
  JOURNAL   J Neurochem 156 (5), 589-603 (2021)
   PUBMED   32083308
  REMARK    GeneRIF: Reelin signaling modulates GABAB receptor function in the
            neocortex.
REFERENCE   2  (bases 1 to 5578)
  AUTHORS   Airik,M., Schuler,M., McCourt,B., Weiss,A.C., Herdman,N.,
            Ludtke,T.H., Widmeier,E., Stolz,D.B., Nejak-Bowen,K.N.,
            Yimlamai,D., Wu,Y.L., Kispert,A., Airik,R. and Hildebrandt,F.
  TITLE     Loss of Anks6 leads to YAP deficiency and liver abnormalities
  JOURNAL   Hum Mol Genet 29 (18), 3064-3080 (2020)
   PUBMED   32886109
REFERENCE   3  (bases 1 to 5578)
  AUTHORS   Zhu,M., Wang,L., Zhu,J., Xu,H., Wei,K., Chen,Q., Wu,X., Miao,X. and
            Lu,Z.
  TITLE     MicroRNA-330 Directs Downregulation of the GABABR2 in the
            Pathogenesis of Pancreatic Cancer Pain
  JOURNAL   J Mol Neurosci 70 (10), 1541-1551 (2020)
   PUBMED   32621101
  REMARK    GeneRIF: MicroRNA-330 Directs Downregulation of the GABABR2 in the
            Pathogenesis of Pancreatic Cancer Pain.
REFERENCE   4  (bases 1 to 5578)
  AUTHORS   Bizzozzero-Hiriart,M., Di Giorgio,N.P., Libertun,C. and
            Lux-Lantos,V.
  TITLE     GABAergic input through GABAB receptors is necessary during a
            perinatal window to shape gene expression of factors critical to
            reproduction such as Kiss1
  JOURNAL   Am J Physiol Endocrinol Metab 318 (6), E901-E919 (2020)
   PUBMED   32286880
  REMARK    GeneRIF: GABAergic input through GABAB receptors is necessary
            during a perinatal window to shape gene expression of factors
            critical to reproduction such as Kiss1.
REFERENCE   5  (bases 1 to 5578)
  AUTHORS   Dinamarca,M.C., Raveh,A., Schneider,A., Fritzius,T., Fruh,S.,
            Rem,P.D., Stawarski,M., Lalanne,T., Turecek,R., Choo,M.,
            Besseyrias,V., Bildl,W., Bentrop,D., Staufenbiel,M., Gassmann,M.,
            Fakler,B., Schwenk,J. and Bettler,B.
  TITLE     Complex formation of APP with GABAB receptors links axonal
            trafficking to amyloidogenic processing
  JOURNAL   Nat Commun 10 (1), 1331 (2019)
   PUBMED   30902970
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5578)
  AUTHORS   Magnaghi,V., Ballabio,M., Cavarretta,I.T., Froestl,W.,
            Lambert,J.J., Zucchi,I. and Melcangi,R.C.
  TITLE     GABAB receptors in Schwann cells influence proliferation and myelin
            protein expression
  JOURNAL   Eur J Neurosci 19 (10), 2641-2649 (2004)
   PUBMED   15147298
REFERENCE   7  (bases 1 to 5578)
  AUTHORS   Ritter,B., Zschuntsch,J., Kvachnina,E., Zhang,W. and
            Ponimaskin,E.G.
  TITLE     The GABA(B) receptor subunits R1 and R2 interact differentially
            with the activation transcription factor ATF4 in mouse brain during
            the postnatal development
  JOURNAL   Brain Res Dev Brain Res 149 (1), 73-77 (2004)
   PUBMED   15013631
REFERENCE   8  (bases 1 to 5578)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
REFERENCE   9  (bases 1 to 5578)
  AUTHORS   Davis,A.M., Henion,T.R. and Tobet,S.A.
  TITLE     Gamma-aminobutyric acidB receptors and the development of the
            ventromedial nucleus of the hypothalamus
  JOURNAL   J Comp Neurol 449 (3), 270-280 (2002)
   PUBMED   12115679
REFERENCE   10 (bases 1 to 5578)
  AUTHORS   Ng,G.Y., Clark,J., Coulombe,N., Ethier,N., Hebert,T.E.,
            Sullivan,R., Kargman,S., Chateauneuf,A., Tsukamoto,N., McDonald,T.,
            Whiting,P., Mezey,E., Johnson,M.P., Liu,Q., Kolakowski,L.F. Jr.,
            Evans,J.F., Bonner,T.I. and O'Neill,G.P.
  TITLE     Identification of a GABAB receptor subunit, gb2, required for
            functional GABAB receptor activity
  JOURNAL   J Biol Chem 274 (12), 7607-7610 (1999)
   PUBMED   10075644
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL831741.16, AL844224.3, BX005247.9, AL772399.9 and BX571848.8.
            
            On May 9, 2018 this sequence version replaced NM_001081141.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14995048.735747.1,
                                           SRR9219381.32172.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-607               AL831741.16        23543-24149         c
            608-745             AL844224.3         26433-26570         c
            746-916             BX005247.9         58188-58358         c
            917-1018            BX005247.9         27545-27646         c
            1019-1084           BX005247.9         15966-16031         c
            1085-1285           BX005247.9         10384-10584         c
            1286-1522           AL772399.9         100824-101060       c
            1523-1583           AL772399.9         62917-62977         c
            1584-1664           AL772399.9         53189-53269         c
            1665-1815           AL772399.9         49749-49899         c
            1816-1948           AL772399.9         47453-47585         c
            1949-2056           AL772399.9         37679-37786         c
            2057-2179           AL772399.9         32181-32303         c
            2180-2290           BX571848.8         37500-37610         c
            2291-2515           BX571848.8         34332-34556         c
            2516-2698           BX571848.8         30698-30880         c
            2699-2828           BX571848.8         27675-27804         c
            2829-2946           BX571848.8         20715-20832         c
            2947-5578           BX571848.8         15546-18177         c
FEATURES             Location/Qualifiers
     source          1..5578
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 25.18 cM"
     gene            1..5578
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /note="gamma-aminobutyric acid type B receptor subunit 2"
                     /db_xref="GeneID:242425"
                     /db_xref="MGI:MGI:2386030"
     exon            1..607
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     CDS             290..3112
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /note="ortholog of human G protein-coupled receptor 51
                     GPR51; gamma-aminobutyric acid (GABA) B receptor, 2"
                     /codon_start=1
                     /product="gamma-aminobutyric acid type B receptor subunit
                     2 precursor"
                     /protein_id="NP_001074610.1"
                     /db_xref="CCDS:CCDS38758.1"
                     /db_xref="GeneID:242425"
                     /db_xref="MGI:MGI:2386030"
                     /translation="MASPPSSGQPRPPPPPPPPARLLLPLLLSLLLSLAPGAWGWARG
                     APRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRL
                     YDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTP
                     VLADKKKYPYFFRTVPSDNAVNPAILKLLKHFRWRRVGTLTQDVQRFSEVRNDLTGVL
                     YGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAFEESMFGSKY
                     QWIIPGWYEPAWWEQVHVEANSSRCLRRSLLAAMEGYIGVDFEPLSSKQIKTISGKTP
                     QQYEREYNSKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDH
                     TLGRIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEI
                     INDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQ
                     KLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTA
                     FGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTV
                     ERYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSI
                     PALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFV
                     PKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLR
                     MKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILSLGNFTESTDGGKAILKNH
                     LDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCV
                     SPCVSPTASPRHRHVPPSFRVMVSGL"
     exon            608..745
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            746..916
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1018
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1084
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1285
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1286..1522
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1583
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1584..1664
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1815
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1948
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            1949..2056
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            2057..2179
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2290
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            2291..2515
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2698
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            2699..2828
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            2829..2946
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     exon            2947..5578
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5534..5539
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /note="hexamer: AATAAA"
     polyA_site      5578
                     /gene="Gabbr2"
                     /gene_synonym="GABABR2; Gb2; Gm425; Gpr51"
                     /note="major polyA site"
ORIGIN      
        1 ggagagaggc gcgcggagac tcggccccct cggcgctcgc tcgctcgctc gctcgttggc
       61 tccccgcctc ccgcactccg ctggctccca ccccttcccg gcgtgattga tccgtcacgg
      121 gcgccgccgc cgccgccgcg gccgttctga gcgagcagaa gccggagccg agccggggcc
      181 cgtgccggcg ccattgcgcg ggagccgcgg gcagagctcg gcgccgggcg gcgggccggg
      241 ccaggccatg cgggccgagt gagctggcgc ccgcagcccg cggcgcggca tggcttcccc
      301 gccgagctcc gggcagcccc ggccgccgcc gccaccgccg ccgcccgcgc gcctgctgct
      361 gcccctgctg ctgtcgttgc tgctgtcgtt ggctcccggg gcctggggct gggcgcgggg
      421 cgccccccgg ccgccgccca gcagcccgcc gctctccatc atgggcctca tgccgctcac
      481 caaggaggtg gccaagggca gcatcgggcg cggcgtgctc cccgccgtgg agctagccat
      541 cgagcagatc cgcaacgagt cactcctgcg cccctacttc ctggacctgc gactctacga
      601 caccgagtgt gacaatgcaa agggactgaa agccttctat gatgcaataa agtatgggcc
      661 gaaccatttg atggtgtttg gaggcgtctg tccgtctgtc acctctatca tcgcggaatc
      721 cctccaaggc tggaacctgg tgcagctttc cttcgccgcc accacgcctg ttcttgcgga
      781 taagaagaag tacccatatt tcttccggac ggtgccctca gacaacgcgg tgaacccggc
      841 aatcctgaag ctgctgaagc acttccgctg gcggcgcgtg ggcacactca cgcaggacgt
      901 gcagcgcttc tccgaggtga ggaacgacct gactggggtt ctgtacgggg aagacattga
      961 gatctcagac acggagagct tctccaatga tccctgcacc agcgtcaaaa agctcaaggg
     1021 gaacgacgtg cggatcatcc ttggccagtt tgaccagaac atggcagcga aagtcttctg
     1081 ttgtgccttt gaggagagca tgtttggcag caagtaccag tggatcatcc cgggctggta
     1141 cgagcctgcg tggtgggaac aggtgcacgt ggaggccaac tcctcacgct gcctgcgcag
     1201 gagcctcctg gctgccatgg aaggctacat cggagtggac ttcgagcccc tgagctccaa
     1261 acaaatcaag accatctcag ggaagactcc acagcaatac gaaagagaat acaacagcaa
     1321 gcgttcgggt gtagggccca gcaagttcca tgggtatgcc tacgatggca tctgggtcat
     1381 cgccaagacc ctgcagaggg ccatggagac actgcatgcc agtagcaggc accagcggat
     1441 ccaggacttc aactacacag accacaccct gggcagaatc atcctcaacg ccatgaacga
     1501 aaccaacttc ttcggagtca cgggtcaagt tgtgttccgg aacggggaaa gaatgggaac
     1561 cattaaattt actcaatttc aagacagcag agaggtgaag gtcggcgagt acaacgctgt
     1621 ggctgacaca ctggagatca tcaacgacac cataaggttc caggggtcgg agccacccaa
     1681 ggacaagacc atcattctag agcagcttcg gaagatctcg cttccactgt atagcatcct
     1741 gtcagctctc actatcctcg gcatgatcat ggccagcgcc ttcctcttct tcaacatcaa
     1801 gaaccggaac caaaagctga tcaagatgtc aagcccctat atgaacaacc tcatcatcct
     1861 gggtgggatg ctgtcctatg catccatctt cctctttggt ctcgatggat ccttcgtctc
     1921 agaaaagacc tttgaaacac tctgcacggt ccggacctgg attctcaccg tgggctacac
     1981 aaccgccttt ggagccatgt ttgcaaagac ctggagggtc catgccatct tcaaaaatgt
     2041 gaaaatgaag aagaagatca tcaaagacca gaagctgctc gtgattgtgg ggggcatgct
     2101 gctgatcgat ctgtgcatcc tgatctgctg gcaggctgtg gaccccctgc ggaggacagt
     2161 ggagcggtac agcatggagc cggacccagc aggacgggac atctccatcc gcccactgct
     2221 ggaacactgc gaaaacaccc acatgaccat ctggctcggc attgtctacg cctacaaggg
     2281 gctcctcatg ttgttcggtt gtttcttagc atgggaaacc cgcaacgtga gcatccctgc
     2341 cctcaacgac agcaagtaca ttgggatgag tgtgtacaat gtggggatca tgtgcatcat
     2401 cggggccgcc gtctccttcc tgacacgtga ccagcccaac gtgcagttct gcatcgtggc
     2461 cctggtcatc atcttctgta gcaccatcac tctctgcctg gtgtttgtgc caaagctcat
     2521 cactctgagg acaaaccctg acgcagccac tcagaacagg cgattccagt tcacacagaa
     2581 ccagaagaaa gaagattcga agacctccac ctcagtcacc agcgtgaacc aggcgagcac
     2641 gtcacgcctg gagggactgc agtcagaaaa ccaccgccta cgaatgaaga tcacagagct
     2701 ggacaaagac ttggaagaag tcaccatgca gctacaagac acaccagaga agaccacata
     2761 catcaaacag aatcactacc aagagctcaa cgacatcctc agcttgggca acttcacaga
     2821 gagcacagat ggaggaaagg ccattctaaa aaatcacctc gatcaaaacc ctcagctcca
     2881 gtggaacacg accgagccct caagaacatg caaagacccc atagaggaca tcaactcccc
     2941 agagcacatc cagcgccggc tgtccctcca gctccccatc ctccaccacg cctacctccc
     3001 gtccattgga ggcgtggacg ccagctgcgt cagcccctgt gtcagcccta cagccagccc
     3061 tcgccacaga cacgtaccac cctccttccg agtcatggtc tcgggcctgt agggcaggga
     3121 ggcctggggc cgggcctcac cgggacagca ccatgctggg ccaaggcgcc tgccactggc
     3181 acgctgacgg cggcgagaag ctgggcacca tgctgcctct ccagactgct ggaatggcgc
     3241 tcaggcagag agggactcag cacggatctc gagccttatc tacgacggtc ttactctcac
     3301 gagggagagg aatggcaatg acttctcctt ggcgtctgca aacaaagagg agttgggatg
     3361 tcagaaactt gcaaaaacaa atcaaactct agacaaagga gagaggcctc agactccagc
     3421 tatcctcgcc aagtggccag agcaagggct ctgcagaaat ggccctctgc actctgcaca
     3481 cacgtcatcg gtggtgcccg cccccacaca ccagcccttc tccactctgg gggagaaggt
     3541 gagcagggcc accaggtccc cagcagctgg cccagcccac ttccgcctcc ctggaacagg
     3601 gagtcagcag gaagggcaga cgggcacagc cctggggctg ggggaccaga gcaggcagct
     3661 gcgcatgctc ccagggaaca tccatcagaa gagagatgtt tgttactctc tgataaatgc
     3721 cacacattaa cacaataaca cccgttctgg ggactgtggg gattcagggc accgcactgc
     3781 agacgtgctc tgcaggatgc aaccgacagt ctgtcatgca cccactgtgt cggctgtatc
     3841 cttgtgttca aatttagggt tcctggtaat aaggggaacc atccgagcta atcatggaat
     3901 gtctactccc agaaaacacg ataaagaaag attgtgcact ttaacctctc ccatgggggc
     3961 ccaagggctg ctgggattcc ccctccccca ctgactttgt ttttgaccaa agtgaatcag
     4021 gggcattctg ctaaaagtca tctctgtgtt cctgagctag agctgctggc ccagggctcc
     4081 ctggcttcca gaaggtagcc ctccagtgcc cttccagccc caacctatga gtgcccgcct
     4141 agggtgtcac tgaagtggtc catcaggagg ctggttctca tccatcatga catacttccc
     4201 ttgaaattga accccaaaga gcaccggcct gggagtcaga cctggatttg agtcctcagt
     4261 cccctcagac tctctccgtg accttgggca agtcaccagt gtctctctga gcctcagttt
     4321 cccctctgta acagactggg gttgaaataa cacccatcct gcctacctca cagggtcact
     4381 ctgaggatgg acacttgatc tcattcatcc aggatagctt tccactgtga agcagctctg
     4441 acctgtgagg tattagtaac gaccatgacc ttcagccctc ccacaagctg ggggtacagt
     4501 gcggcccaga gaaacttcct gcaaggccct ctacctagga acaggacagc ccagtcagag
     4561 ggaggctctt ctgacagtcc ttgataggtt cattctttgc taaaagcctg aatggcaccg
     4621 tccaggggcg tctgcacaaa tgcgtggttt gcttactccc taaagaaatc ctaaaggcag
     4681 cttcaacggg caggcaataa tctctttcca gaccactgca gtcaggaaca cactgctgtc
     4741 aaccaccagg ctgtgacaga gggcccacgg gaatcaccat cgccaacatt ttgaaacacc
     4801 ctagttcatg tcacatagct ctcccttccc ctccctcaaa gagaggttac gaaggttctg
     4861 tagcttttta agggggaaaa aatgtcaaca catcacaggt caagttgatg tccttctctg
     4921 tttaggcacc caaactccat gttgtcactc actgtgtgtg ttaaccagta ttcccttgct
     4981 ttttcgactt caccgaaacc aaatttcatt taaaagacca cattattttt tttcaaaggg
     5041 aaagataatt aactgtacat aatgtataca gacaaaaaaa aacctgtaga aatattactc
     5101 cagcatagca ggaaaaaaaa aaacaaaaat caaaaaacaa aagtattgga ttgtcggagg
     5161 tgagcgtgtg tctgtaatcc cttgtgactc cgaactgtgc tctgtcttct aggttaaccc
     5221 acaagataca tctctgtcta ctgatcctgt aggttcaccc acattttttt tttaatttct
     5281 ctgcaattaa caagccccac aaagtgattc tggctatctc ctggttctgt tcttttatat
     5341 gcagcaaaca cacggtccat ttcctagagg cttccgccca agggcatctt ccagtgacgc
     5401 tagtgcacac acacacacac acacacacac acacacacac acacacacga ctgctttcaa
     5461 ttagaccgga actggcagaa tcaagtgtaa aaatgaggcg tttctcttgc cccactgcat
     5521 ggtatcgatt tttaataaat tgttgcaaat ttgtttttat gaataaaagg ggaaaata
//
