LOCUS       NM_027226               4397 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus forty-two-three domain containing 1 (Fyttd1),
            transcript variant 1, mRNA.
ACCESSION   NM_027226 NM_027515
VERSION     NM_027226.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4397)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4397)
  AUTHORS   Bhattacharjee,R., Jolly,L.A., Corbett,M.A., Wee,I.C., Rao,S.R.,
            Gardner,A.E., Ritchie,T., van Hugte,E.J.H., Ciptasari,U., Piltz,S.,
            Noll,J.E., Nazri,N., van Eyk,C.L., White,M., Fornarino,D.,
            Poulton,C., Baynam,G., Collins-Praino,L.E., Snel,M.F., Nadif
            Kasri,N., Hemsley,K.M., Thomas,P.Q., Kumar,R. and Gecz,J.
  TITLE     Compromised transcription-mRNA export factor THOC2 causes R-loop
            accumulation, DNA damage and adverse neurodevelopment
  JOURNAL   Nat Commun 15 (1), 1210 (2024)
   PUBMED   38331934
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4397)
  AUTHORS   Liu,H.B., Muhammad,T., Guo,Y., Li,M.J., Sha,Q.Q., Zhang,C.X.,
            Liu,H., Zhao,S.G., Zhao,H., Zhang,H., Du,Y.Z., Sun,K., Liu,K.,
            Lu,G., Guo,X.J., Sha,J., Fan,H.Y., Gao,F. and Chen,Z.J.
  TITLE     RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator
            in Early Zygotic Genome Activation
  JOURNAL   Adv Sci (Weinh) 6 (15), 1900295 (2019)
   PUBMED   31406667
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4397)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   5  (bases 1 to 4397)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY060615.1, AK170511.1 and AC139244.4.
            
            On Apr 15, 2009 this sequence version replaced NM_027226.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029785.1, AK161252.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                BY060615.1         1-29
            30-3261             AK170511.1         2-3233
            3262-4397           AC139244.4         199947-201082
FEATURES             Location/Qualifiers
     source          1..4397
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="NOD"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 23.43 cM"
     gene            1..4397
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /note="forty-two-three domain containing 1"
                     /db_xref="GeneID:69823"
                     /db_xref="MGI:MGI:1917955"
     exon            1..213
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..1064
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UAP56-interacting factor; protein 40-2-3; forty-two-three
                     domain-containing protein 1"
                     /codon_start=1
                     /product="UAP56-interacting factor isoform 1"
                     /protein_id="NP_081502.2"
                     /db_xref="CCDS:CCDS28125.1"
                     /db_xref="GeneID:69823"
                     /db_xref="MGI:MGI:1917955"
                     /translation="MNRFGTRLVGATATPPPPPKARSNENLDKIDMSLDDIIKLNRKE
                     GKKQNFPRLNRRLQQSGTRQFRMRVRWGIQQNSGFGKTSLSRRGRVLPGKRRPYGVIT
                     GLAARKATGIRKGISPMNRPPLSDKNIERYFPALKRKTSLLRQNEVQRKQVAVLKRPN
                     QLNRKNNIPANFTRNGNKLSHQKDTRQATFLFRRGLKVQTQLNTEQLIDDVVAKRTRQ
                     WRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQ
                     FDINSVGKQTGMTLNERFGILKEQRANLTFSKGGSRFVTVG"
     exon            214..342
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            343..491
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            492..604
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            605..701
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            702..763
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            764..838
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            839..965
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            966..4397
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3841..3846
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3860
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /note="major polyA site"
     regulatory      4291..4296
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      4316
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
     regulatory      4346..4351
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      4378
                     /gene="Fyttd1"
                     /gene_synonym="2010005M05Rik; 3830411L18Rik;
                     3830421F13Rik; 4933423A17Rik"
ORIGIN      
        1 ggcgcgcgtg cgcgctctgc gctgcagcta gtctgcgtgc gtgagtggga ggcggcgggc
       61 ctgcgactct ggccttcccg gctgactgct ccgacgccgc aaccccagtc atgaaccggt
      121 ttggcacccg gttggtagga gccacggcga ccccgccgcc gccaccgaaa gcacgaagca
      181 atgagaacct ggacaaaatc gatatgtccc tggatgatat tatcaaactg aatagaaagg
      241 agggaaagaa gcaaaacttt ccaagactaa atagaagact ccagcaaagt ggtacccggc
      301 aattcaggat gagagtacgg tggggaatcc agcagaattc tggttttggt aaaactagtt
      361 tgagccgtag aggaagagta ttgcctggaa aaagacgtcc ttatggagtt atcaccggcc
      421 ttgcagccag gaaagcaact gggattcgaa aaggaataag tcctatgaat cgtccacctc
      481 taagtgacaa gaatatagaa cgatattttc cagcattgaa aaggaagaca agccttctga
      541 gacagaatga agtacaaagg aaacaagttg ctgttctcaa aagacctaat cagttaaaca
      601 gaaaaaataa cattccagct aattttacca ggaatggaaa taaattaagt catcagaaag
      661 acactcgtca ggcaaccttt cttttccgaa gaggcctgaa ggttcagacc cagttgaaca
      721 cagaacaact gatagatgat gtggtagcaa agagaacgcg tcaatggcgt acttccacca
      781 caaatggagg aattttgact gtatccattg acaatcctgg agctgtacag tgtccggtaa
      841 ctcagaaacc acgattaact cgtactgctg tgccctcatt cttgacaaaa agagaacagt
      901 ctgatgttaa gaaagttcct aaaggcgtcc ctctacagtt tgacataaat agtgtgggaa
      961 aacagacagg gatgactttg aatgaacgat ttgggatact gaaagagcaa agagccaacc
     1021 tcacgttcag caaaggagga agccgctttg tgactgtggg atagatccgt gtccaaggaa
     1081 ctttaagtgt tgactgtttg aaaagttgat ttgcttgaag agttcatcgg agaagttcaa
     1141 gaaactttcc ttcagaatat tcacaagcct aaataacttt atttttgaag gttattttgt
     1201 tttggtttgg tttttttaat gtataaataa tgccctgaaa gaatagcagg gaatatacct
     1261 atctgttctt aaagatttca tggttggccc atacaaagca attctctgtt gacttctttg
     1321 actcctcctg aagcagaagg aagacagaaa gacagacatt gattattttt atgagcgtgg
     1381 gatttaggat ctcatcactt ttatccagtt tttaggattt gccatggtaa atcttaaact
     1441 tgagaaataa gagtacacct ctgtgttgtc acttacccat ttatgtatgt gttggcgtga
     1501 caaggacagc tgcctttctg tcattactgg tgttttctaa actgtaggag aattttggtt
     1561 ttgacttttg aggcttatgg aaatatttag aacttggttc atttttcagt tattgttagc
     1621 ttaaactccc taagttctaa gaacttagta ttaaactttt aataaaaaaa aaaatgtggc
     1681 tctcaggatt agtctcaggc caaaatgtgt tagggctgta aatgcttatt tacaaagtta
     1741 tctgctaggt ccttggagga gacgcctggt gtggaacctg atggtctgtg ttcagtataa
     1801 atggagaaga catgaaaggc attggccaac ggacagattg gacatgggaa caataaagcc
     1861 tgagtcatag ctctgccatc tgggttgact tctgtcctga gtctagtgtc tgtagattct
     1921 tctataaatg atgcttacaa gaattacaat ttttaaaatg agttgaatct tgggtatttt
     1981 gacaatatac ttactagata tataaagtcc tatgtttcat attcaaaagt tttttttgta
     2041 aagctcttaa actcagtaag ttcaataatt tataactccc caaacaaaaa tctacttata
     2101 tatgtcacaa aggagagaaa aaaaagtaaa ttataatgaa gttacattta actatacaca
     2161 ctcactccgt ttcttctatt gctcaaagtt caggcattat aggaaaaagg gtttttttgt
     2221 tttgttttgt tttttcttac actggaggac ggtctgctgt gccgagatag tgctgagatt
     2281 gctcagtcat aggtcataaa ttacaatgag atgccaaaat gcagcggcgt gtcccagcta
     2341 cagattatca gtgctgagag tgctcacatg gtcataggtc ataaattaca gtgagatgcc
     2401 aaaatgcagc ggcgtgtccc agctacagat taccaagtgt ggtcattttg aaacctgacc
     2461 ttttgttttg ctgtgatttc aagtttgagt gggtgtttaa gtctctgctg ttgatttctc
     2521 ctgtaaagac agagcattat actcctgccc gccttcattg tgtcctagac ttcattgtct
     2581 ttgatgttct tcaagttctt actggcttgt gctagttgtg ggaaaaacag caacaatgtc
     2641 atgcttatac caaagatcta aatctttcct cagcatctgt taatctgcca ggacttggac
     2701 ttgagagggg tttagaggct aatcacagaa tttgaaagta agctccagtt ctccttagct
     2761 gtaatgcttt tcattgaggc caaggactca taaaacattt ttgccaatat gaatatttat
     2821 atttggttca gaaacaaaac attttagagt ggtttgctgg tagcttattt taaagcaaag
     2881 gaaaaacaat tgagcatgaa cactatcttt ggaacaattt ttaaaatatg atataaaagt
     2941 ttttgtttct tgttgtttta aatattacta tacagaggta ttagtaattc catttttgga
     3001 aaatcttaaa aatcgcccaa atgttgacac taagtacatt gaaaaacagt gtctttggta
     3061 tagtaaatgt ttgttcttca ttcatctgta acttaatatt tgttcaaatt ttgcctttga
     3121 tacaactaag ttaaaactct tgagtgctga cctgttgtat atacacaaaa caatctgctt
     3181 tgttggagaa aaattccctc tcttggaatg tgattgtagt catccttgtt cagttcttga
     3241 agcccccccc cccttttttt ttaattttat ttaaacaggg tgcaacgtaa aatttccttt
     3301 gcatcaaggt gtatgcagaa cattgatgca gtgcatcacg acgtgagcgt ttgtatttaa
     3361 cgaggaggtg ctttacactg tactttttgg tgttttttgg aaaagttaca ttagatttgt
     3421 tctgaagctg ttcatttttg acaaataaaa tgtaacaggt ttcacatgag ttattctgag
     3481 ctataaagat tgagttgtgg ttttttagat tgttgtgtgt tacaaagcat cttatagtgg
     3541 ttttatatat gatttctggg atttgaagtt gctgatcagc taaatctcca ctcttggtgt
     3601 tcctctgact tttgaccatt tcatgcatgg gtgacctgag gttccaacat gaggccacca
     3661 aggcgaatta aagatagtca cattgttata acgcagagca cagaagtaga tgagccttta
     3721 gagatgatct gcgtcagccc ctcctcttac atcgtagtta agtgacaccc gacattttct
     3781 aagacgtaca tggaacatgg gtcatgtttt gagcctcatg tcttataatt ctcagtggac
     3841 aataaacgac ttcacacata ggcagtagtt ttgtggtatt taatgtgtca ggtgtctaag
     3901 aattagtaat atccctatat cagcatttgt ggtgtgctca gtaaatctac tcttccaata
     3961 attcctattt aattactttg atatggaagt tactgaaact cattacaaaa ggccaatgtt
     4021 ttcagtatac accgggaaga tgattgctaa ttccagaccc catgtcgaaa aacttacaca
     4081 cagaggagaa agactggtgg tcgaatctgt cgtgtatttt taaatataca ctcacttttc
     4141 actatattaa ttataatcaa attataaagc atttatgttt aagaaacatg ggtataattg
     4201 tcaacatttt agttttgtta gaggtgcata ttaaatgtta ctgcctgtaa tgtaattcat
     4261 aaaatatatg caatttgggg gtatgaagag attaaaaaat ttacttgtca tacaaagaat
     4321 tccatatatt ccaaatgcaa gcaatattaa agcaaaaaag agcttcctcc tttctgaaga
     4381 gaaggcctct tacattg
//
