LOCUS       NM_025799               5729 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Mus musculus fucosidase, alpha-L- 2, plasma (Fuca2), transcript
            variant 1, mRNA.
ACCESSION   NM_025799
VERSION     NM_025799.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5729)
  AUTHORS   Phopin,K., Nimlamool,W., Lowe-Krentz,L.J., Douglass,E.W.,
            Taroni,J.N. and Bean,B.S.
  TITLE     Roles of mouse sperm-associated alpha-L-fucosidases in
            fertilization
  JOURNAL   Mol Reprod Dev 80 (4), 273-285 (2013)
   PUBMED   23426913
REFERENCE   2  (bases 1 to 5729)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   3  (bases 1 to 5729)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK030320.1, AC153979.3, CK343852.1 and AI841078.1.
            
            [WARNING] On Apr 23, 2024 this sequence was replaced by
            NM_025799.6.
            
            On Aug 19, 2016 this sequence version replaced NM_025799.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK030320.1, AK044790.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1721              AK030320.1         3-1723
            1722-1722           AC153979.3         43872-43872
            1723-3954           AK030320.1         1725-3956
            3955-5158           AC153979.3         46105-47308
            5159-5712           CK343852.1         1-554               c
            5713-5729           AI841078.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..5729
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 4.86 cM"
     gene            1..5729
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /note="fucosidase, alpha-L- 2, plasma"
                     /db_xref="GeneID:66848"
                     /db_xref="MGI:MGI:1914098"
     exon            1..346
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..1526
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /EC_number="3.2.1.51"
                     /note="alpha-L-fucoside fucohydrolase 2; plasma
                     alpha-L-fucosidase"
                     /codon_start=1
                     /product="plasma alpha-L-fucosidase precursor"
                     /protein_id="NP_080075.2"
                     /db_xref="CCDS:CCDS23701.1"
                     /db_xref="GeneID:66848"
                     /db_xref="MGI:MGI:1914098"
                     /translation="MRLGFLMLLPLLLLPLLRPWGVTRALSYDPTWESLDRRPLPAWF
                     DQAKFGIFIHWGVFSVPSFGSEWFWWYWQKEKKPQFVDFMNNNYAPGFKYEDFVVLFT
                     AKYFNANQWADILQASGAKYVVFTSKHHEGFTMWGSDRSWNWNAVDEGPKRDIVKELE
                     VAVRNRTGLHFGLYYSLFEWFHPLFLEDQSSSFQKQRFPVSKTLPELYELVNRYQPEV
                     LWSDGDGGAPDHYWNSTGFLAWLYNESPVRKTVVTNDRWGVGSICKHGGYYTCSDRYN
                     PGYLLPHKWENCMTIDKFSWGYRREAEISDYLTIEELVKKLVETVACGGNLLMNIGPT
                     GDGTIPVIFEERLRQMGTWLKVNGEAIYETHTWRSQNDTVTPDVWYTSKPEKKLVYAI
                     FLKWPISGKLFLGQPIGSLGETEVELLGHWQPLTWTSSQPSGITVELPLLSVHQMPCK
                     WGWTLVLSNVI"
     exon            347..534
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            535..874
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            875..1085
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1276
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1385
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..5714
                     /gene="Fuca2"
                     /gene_synonym="0610025O11Rik; 5530401P20Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtctgggtc aggtgacagg agcagggtac acttagcaga agccggaagg ccagcgctag
       61 gcagcttctg cggctgacag agaaggttcc cggcttccct ggtgactggc ggttcccccg
      121 aggatcccag gctggcgcgc atgcgcctgg ggttcctgat gcttctgccg ctgctgctgc
      181 tgccgctcct gaggccttgg ggggtcacga gagcccttag ctatgacccc acttgggaat
      241 ctctggacag acgcccgctg ccagcctggt tcgaccaggc caagttcggc atctttatcc
      301 actggggagt gttctccgtg cccagctttg gtagtgaatg gttctggtgg tattggcaaa
      361 aggagaagaa accccagttt gtggacttta tgaacaataa ttatgctcct ggttttaagt
      421 atgaagattt tgtagtgcta tttacagcca agtattttaa tgcaaaccag tgggcagata
      481 ttctccaggc ctctggtgcc aaatatgtgg tcttcacttc taaacatcac gaaggcttta
      541 caatgtgggg ctcagaccgt tcttggaact ggaatgcagt cgatgagggg ccaaagaggg
      601 acattgtcaa ggagcttgag gtggctgtga ggaacaggac tggcttgcac tttggtctgt
      661 actattctct ttttgaatgg ttccatccgc tctttctgga ggatcagtcc agctcattcc
      721 aaaagcagcg atttcccgtt tctaagacat tgcctgagct ctatgagttg gtgaacagat
      781 accagcctga agtcctgtgg tcagacggag atgggggcgc gccagatcac tactggaaca
      841 gcactggctt cttagcctgg ctgtataatg aaagcccagt tcggaaaaca gtagtcacca
      901 atgatcgctg gggagtcggg tctatctgca aacatggtgg ctactatact tgcagtgacc
      961 gttacaatcc tggctatctc ttgccacaca aatgggaaaa ctgcatgaca atagataagt
     1021 tctcctgggg ctacaggcgg gaagctgaaa tcagtgatta tcttacaatt gaagagttgg
     1081 tgaagaaact tgtggaaaca gtcgcatgtg gtggaaatct tttgatgaat attggtccca
     1141 cgggagacgg caccattcct gtcatttttg aggagcgatt aaggcaaatg ggaacctggc
     1201 tgaaggtcaa cggggaagct atttatgaaa cacacacttg gaggtctcag aatgacactg
     1261 tcactccgga tgtgtggtac acatctaaac ccgagaagaa attagtctat gctatttttc
     1321 ttaaatggcc catctctgga aagctgtttc ttggacaacc cataggtagt ctgggggaaa
     1381 cagaggtaga actgctgggc cattggcagc cactgacttg gacatcttca cagcccagtg
     1441 gcatcaccgt ggagttacct ctgctcagcg tacatcagat gccctgtaaa tggggatgga
     1501 ctcttgtgct aagtaatgtg atttaacctg cagcagaaag atgtaagctg caggtacctc
     1561 taactacagg aaatggcagg gttttttgtg ttttgttttt aaagtaccac taaagaaatc
     1621 aggataaaaa tgatacaaaa actgaaatca ttaggtaata cagtttccct tcttgttctt
     1681 cctaaattct ttcctaaacc actcgtgtta ccatttgact atgcttccct ccaaagtctc
     1741 ttcctgctga atccatttca catgtaactc acaggtgcaa atattttttt ttcagagaag
     1801 ctagaaactc ctaaccttct actgaaacct taacactcca cgtggctgta ttggaaacag
     1861 agctcttgaa atggtcaaga ttaaaccatc atagggctag ccctaatacc agaggacttg
     1921 gtgtcttata agggagagac aataaagatg caaaaccacc ggggaaagcc atgcaaagaa
     1981 gacagttatc cgcaagccaa ggagaagagt gcaggagaaa ccgaatctct ctaacaccct
     2041 catcttggac ttctatcctc taggactgtg aggaaatata acttcctgtt gttgaagcca
     2101 tccaggatgt ctttggtctt ccccatacct cctatcataa atcctcatat ataatgcaga
     2161 ctatgtaatg aatttgatta gatatatgtg tccaatgaat tccgtaatta tcttttcatc
     2221 ttaaagactt ccctcatatt cattttctat ttgcttctat ttgctgtaga aattttgaaa
     2281 tacaagtcac cgcctagacc actgcaatta ttttataata ttttagtatg tattcttcca
     2341 atttggggac agaaagaggt gtgagattgg agggataggg ttatttgttt taatgagggc
     2401 taaaacaggt tgtaaaccta gttgaaaatt gggaaggtgt tattagcttc ttttctgttc
     2461 ctgtcatgaa acataatgac caaagcagta tactggagga agagtttatc atggcttata
     2521 gtgtcagagg gttatatgag agtctgtcat agtatgaaga tacagcagca gatgagcaca
     2581 gcagctggag accaccacat cttcaactgc tagcatgagg cagagagtga actgggtagg
     2641 gtgagcacta tacctgtggt tttctacctt cctaatgctg caaccctttt tatagttcct
     2701 tatgttgtgg tgaactgccc cccccccata caattatttt tgtgtgtgta attttgctac
     2761 tggtatgaat tgcaatgtaa atatttttga agatagaggt ttgccagagg ggtcacgacc
     2821 ctcaggttgt gagagcacca ctgctctaat ctatcaatgc ctactggccc tgcggtacac
     2881 gtccttcagg aaggctgtgt cacccaactc ttcccaaatg gtgccaccaa ctgaagacca
     2941 agtgttcaaa tacccgaatc tatggagaat ttttctcatc caatccccct cccccatcca
     3001 cccactccca accccacaca caaatagcct actaagatct ttgtctaagt ttcttttctg
     3061 ttgctgtgac aaaacactgt gagcaaggga acgtataaga gagagagtgt ttaactgggc
     3121 ttgtgggtac agaagactgg agcctacagt ggcagagcga aggtgtggag gtaggcagct
     3181 gagcagctgc tgagagctca catagtgatc catatgcagt agacagagaa acactagaga
     3241 aagctgacaa gcctcctcca gcatgctagc acctcctaat ccttctcaaa cttccatcga
     3301 atgagaagca agtattcaaa ctttaggcaa caggggccat tctcattcaa actaccactg
     3361 tgttcctgta aaataagata aaaataattg tagcagaatt ctcccctaat taattacata
     3421 ataaggatga ctagaagaca atcacggggc aagtagcagg tgggccttcc aagtaagaga
     3481 gaggaagagg aagggaatgc aggaggaggg cacccagaat ctgccactgg aagatttcta
     3541 acagaatagt taatgagttt agggtgatag attctgcacc caggagttgt gttatctgtt
     3601 gattctaaac caagacagtc tggtgttttc catttgctgt gactcaactg agctctaggg
     3661 gaaaggtacc tgcagaggag catgggttgg tgagagtgcg cccccagcta gctttggaca
     3721 tttgggtgtg ttgagcggtt tggcagcacc tagctgcagg ggttgggtga ctggaaactg
     3781 cacctcagca gcaagcatgg cgaaccacca catggggata gccacggggg cagggagact
     3841 gcctcagcca gtgtagccgg tgatagcatg gattgatttt ttaattatta cacataaaaa
     3901 taatagtgac tctgatacat gtttaaagaa aaattgatta aagaactcat tcccaaaagg
     3961 tgttctcaac atgggcagat gtgatgatgc gcacctatat ccattcccag actagagagg
     4021 ctgaggcaag agggtcacaa gctcagggcc agcatgcact acaatagcta cacagaccat
     4081 ctcaaacaaa acaaatattt ttaaatggtc atatcctttt tgttatatta tgtattcaaa
     4141 ttcattgttt ttttttttta attatttaag gcctggcaac tgttagctca tgcctttaat
     4201 cccagtgctt agggggcaga ggcaggcata tctgcctatc tttaagttca aggccagcct
     4261 ggtctacaga gcaagttcca ggacagccag ggctacacag agaaacactg tcttgaaaaa
     4321 ccaaaaccaa ccaactaaac aaacaaacaa aaaatatata tacctcctaa agtttctctt
     4381 cgaggttggc atcttctaag acatccattg ctgaagacct tgcaactatc aagacttgtt
     4441 cttcttgaga caagactcac tatgttgtcc agactggact taaatttttt gggttcaagc
     4501 aatcttactg cctatgtctt caagtagcag ggaatacaga tgtgccccat cacacctggg
     4561 tgagagtacc aactacccaa aactatgcca aaatattcat ggggaaaata tttgttcatc
     4621 ctaaatctca atattttatt agagagccat tatgtatata tgttgaaatg atcaacttct
     4681 gcaccaagaa aacacacaca cacacacaca cacacacaca cacacacaca cacactctct
     4741 tttttacatt tttcttttca ttaattattt attcacttta catctgatca caaccctccc
     4801 cgtcttgggg cttcttctcc tcacatggta cttcccatca tttcccctcc catatcctct
     4861 gagaatgggg aggtccctct gggtatcacc tcatcctggc ccatcaagtc actccaggac
     4921 tgggtacatc ctttcccact gagaccagac aaggcagtcc agttagggga atgggatcct
     4981 caggcaggca acagagtcag ggacattgtt ggggggcttg catgaagact aagctgtaca
     5041 tctgttataa atgtgtgagg gggtgagggg gtgggcctag gtctggccca tgcttagtct
     5101 ttggttggag ggaaaccaca aaaatttaaa aaggaacaaa gccaaacaaa aatctaaagc
     5161 agcgttgtta agaatcttga cacagatatt gagtcatctg cttaagaaag tgtttttaag
     5221 agaaaagaaa acgagaactg cttaaattct ttacttgata tagttgaaag taaaagaaga
     5281 taagatgcct aaagcaaata gtatacaggg tttagctgat gagcagctgt atttattacg
     5341 gccacattac tggaattaaa cactggactt aaaacaatgt gaggatacag ttaccatggt
     5401 gagacccgca cagttggagc gtgagacagc tggttacatt gggtctgcaa atgaggctgt
     5461 ggggaaatga atgtttggcc gacacttgtt gtttttctgt atcccccacc cttctctctc
     5521 cttccttcct ttccagtcag acccagacca tggaatgatg ttacctatct agtctttgta
     5581 cccaagttgt agctctccat aaatgccctc acaggtgcat tcagaggtgg gtccaaatcc
     5641 agttagattg gaaaattaac catcacagta cttcataact taacatgcaa ataaatacat
     5701 tttgttaacc ctaaaaaaaa aaaaaaaaa
//
