LOCUS       NM_001355368            6584 bp    mRNA    linear   ROD 08-FEB-2024
DEFINITION  Mus musculus far upstream element (FUSE) binding protein 1 (Fubp1),
            transcript variant 3, mRNA.
ACCESSION   NM_001355368 XM_006501669
VERSION     NM_001355368.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6584)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6584)
  AUTHORS   Zheng,Y., Dubois,W., Benham,C., Batchelor,E. and Levens,D.
  TITLE     FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC
            expression in primary single murine cells
  JOURNAL   Commun Biol 3 (1), 545 (2020)
   PUBMED   33005010
  REMARK    GeneRIF: FUBP1 and FUBP2 enforce distinct epigenetic setpoints for
            MYC expression in primary single murine cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6584)
  AUTHORS   Zhang,X.X., Chen,H., Li,H.Y., Chen,R., He,L., Yang,J.L., Xiao,L.L.
            and Chen,J.L.
  TITLE     Long non-coding RNA small nucleolar RNA host gene 6 aggravates
            pancreatic cancer through upregulation of far upstream element
            binding protein 1 by sponging microRNA-26a-5p
  JOURNAL   Chin Med J (Engl) 133 (10), 1211-1220 (2020)
   PUBMED   32433053
  REMARK    GeneRIF: Long non-coding RNA small nucleolar RNA host gene 6
            aggravates pancreatic cancer through upregulation of far upstream
            element binding protein 1 by sponging microRNA-26a-5p.
REFERENCE   4  (bases 1 to 6584)
  AUTHORS   Hoang,V.T., Verma,D., Godavarthy,P.S., Llavona,P., Steiner,M.,
            Gerlach,K., Michels,B.E., Bohnenberger,H., Wachter,A.,
            Oellerich,T., Muller-Kuller,U., Weissenberger,E., Voutsinas,J.M.,
            Oehler,V.G., Farin,H.F., Zornig,M. and Krause,D.S.
  TITLE     The transcriptional regulator FUBP1 influences disease outcome in
            murine and human myeloid leukemia
  JOURNAL   Leukemia 33 (7), 1700-1712 (2019)
   PUBMED   30635626
  REMARK    GeneRIF: High FUBP1 expression is associated with myeloid leukemia.
REFERENCE   5  (bases 1 to 6584)
  AUTHORS   Kang,M., Lee,S.M., Kim,W., Lee,K.H. and Kim,D.Y.
  TITLE     Fubp1 supports the lactate-Akt-mTOR axis through the upregulation
            of Hk1 and Hk2
  JOURNAL   Biochem Biophys Res Commun 512 (1), 93-99 (2019)
   PUBMED   30871777
  REMARK    GeneRIF: Fubp1 upregulates the mRNA levels of two hexokinase genes,
            Hk1 and Hk2. We suggest that Fubp1 contributes to cell survival
            through supporting lactate-Akt-mTOR axis.
REFERENCE   6  (bases 1 to 6584)
  AUTHORS   Contos,J.J. and Chun,J.
  TITLE     The mouse lp(A3)/Edg7 lysophosphatidic acid receptor gene: genomic
            structure, chromosomal localization, and expression pattern
  JOURNAL   Gene 267 (2), 243-253 (2001)
   PUBMED   11313151
  REMARK    Erratum:[Gene 2001 Jul 11;272(1-2):345]
REFERENCE   7  (bases 1 to 6584)
  AUTHORS   Ring,H.Z., Vameghi-Meyers,V., Min,H., Nikolic,J.M., Black,D.L. and
            Francke,U.
  TITLE     The mouse Fubp gene maps near the distal end of chromosome 3
  JOURNAL   Genomics 56 (3), 357-358 (1999)
   PUBMED   10087207
REFERENCE   8  (bases 1 to 6584)
  AUTHORS   Wang,X., Avigan,M. and Norgren,R.B. Jr.
  TITLE     FUSE-binding protein is developmentally regulated and is highly
            expressed in mouse and chicken embryonic brain
  JOURNAL   Neurosci Lett 252 (3), 191-194 (1998)
   PUBMED   9739993
REFERENCE   9  (bases 1 to 6584)
  AUTHORS   Craig,J.C., Eberwine,J.H., Calvin,J.A., Wlodarczyk,B., Bennett,G.D.
            and Finnell,R.H.
  TITLE     Developmental expression of morphoregulatory genes in the mouse
            embryo: an analytical approach using a novel technology
  JOURNAL   Biochem Mol Med 60 (2), 81-91 (1997)
   PUBMED   9169087
REFERENCE   10 (bases 1 to 6584)
  AUTHORS   Davis-Smyth,T., Duncan,R.C., Zheng,T., Michelotti,G. and Levens,D.
  TITLE     The far upstream element-binding proteins comprise an ancient
            family of single-strand DNA-binding transactivators
  JOURNAL   J Biol Chem 271 (49), 31679-31687 (1996)
   PUBMED   8940189
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123075.5.
            
            [WARNING] On Mar 22, 2024 this sequence was replaced by
            NM_001355368.2.
            
            On Sep 15, 2017 this sequence version replaced XM_006501669.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.186294.1,
                                           SRR7345562.1995732.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-279               AC123075.5         128457-128735       c
            280-370             AC123075.5         125090-125180       c
            371-433             AC123075.5         124270-124332       c
            434-472             AC123075.5         123527-123565       c
            473-512             AC123075.5         121709-121748       c
            513-565             AC123075.5         121273-121325       c
            566-637             AC123075.5         121110-121181       c
            638-695             AC123075.5         120887-120944       c
            696-858             AC123075.5         119311-119473       c
            859-957             AC123075.5         119126-119224       c
            958-1059            AC123075.5         118920-119021       c
            1060-1162           AC123075.5         118590-118692       c
            1163-1263           AC123075.5         118371-118471       c
            1264-1405           AC123075.5         117749-117890       c
            1406-1566           AC123075.5         116913-117073       c
            1567-1718           AC123075.5         116177-116328       c
            1719-1798           AC123075.5         115792-115871       c
            1799-1927           AC123075.5         112949-113077       c
            1928-2002           AC123075.5         110912-110986       c
            2003-2148           AC123075.5         107135-107280       c
            2149-6584           AC123075.5         102327-106762       c
FEATURES             Location/Qualifiers
     source          1..6584
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 77.05 cM"
     gene            1..6584
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /note="far upstream element (FUSE) binding protein 1"
                     /db_xref="GeneID:51886"
                     /db_xref="MGI:MGI:1196294"
     exon            1..279
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..2157
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /note="isoform 3 is encoded by transcript variant 3; far
                     upstream element (FUSE) binding protein 4; far upstream
                     element-binding protein 1; FUSE-binding protein 1"
                     /codon_start=1
                     /product="far upstream element-binding protein 1 isoform
                     3"
                     /protein_id="NP_001342297.1"
                     /db_xref="GeneID:51886"
                     /db_xref="MGI:MGI:1196294"
                     /translation="MADYSTVPPPSSGSAGGGGGGVVNDAFKDALQRARQIAAKIGGD
                     AGTSLNSNDYGYGGQKRPLEDGDGSWTNPSSTTHWEGMPSPFKDQPDAKKVPPQNDSF
                     GAQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGL
                     PERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVI
                     GKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQG
                     GFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGT
                     TPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGG
                     LQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRSPPPNADPNMKLFTIRGTP
                     QQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNP
                     GPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGADPNSAAWAAYYAHYYQQQA
                     QPPPAAPAGAPATTQTNGQGDQQAPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGG
                     QPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ"
     exon            280..370
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            371..433
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            434..472
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            473..512
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            513..565
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            566..637
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            638..695
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            696..858
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            859..957
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1059
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1162
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1263
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1405
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1566
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1718
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..1798
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..1927
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2002
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2148
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
     exon            2149..6584
                     /gene="Fubp1"
                     /gene_synonym="9530027K12Rik; D3Ertd330e; FBP; Fubp;
                     Fubp4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgaaacat cgcgggattt ccgtctgcca gtctccgccc ctttacggca cgatggtcgt
       61 gcaagaatgt gatagagcct cgacggccgc catcttcttc ctttcttagc agttaaccga
      121 gagcggcgcc tccctccgcg aggaaacggc agcgtgtgct gtagcgtggg tatggccgac
      181 tactccacag tgcctccgcc gtcgtctggc tcggctggcg gcggcggcgg cggagtcgtt
      241 aacgacgctt tcaaagatgc cctgcagaga gcgcggcaga ttgcagcaaa aattgggggt
      301 gatgctggta catcattgaa ttcaaatgac tatggttatg ggggacaaaa aagaccctta
      361 gaagatggag atggctcttg gacaaatccg agcagtacca cacactggga gggaatgccc
      421 tctcctttta aagatcagcc agatgctaag aaagtacctc cccaaaatga ctcttttgga
      481 gcacagttac ctccaatgca tcagcagcaa agcagatctg taatgacaga agaatacaaa
      541 gtcccagatg ggatggtcgg atttataatt ggcagaggag gtgaacagat ctcacgaata
      601 cagcaggaat ctggatgcaa gatacagata gcacctgata gtggtggcct accagaaagg
      661 tcttgtatgc taactggaac acctgaatct gtccaatcag caaaaagatt attggaccag
      721 attgttgaaa agggaagacc agcccctggc tttcatcatg gtgatggacc tggaaatgca
      781 gttcaggaaa tcatgattcc agccagcaaa gcaggactag ttattggaaa ggggggcgag
      841 actattaaac aacttcagga acgggctggt gttaaaatgg taatgattca agatgggcct
      901 caaaacactg gtgctgataa acctcttagg attacgggtg acccatacaa agttcagcaa
      961 gccaaggaaa tggtattaga gttaattcgt gatcaaggtg gtttcagaga agtgcggaat
     1021 gagtatggct caagaatagg aggcaatgaa gggatagatg tcccaattcc aagatttgct
     1081 gttggcattg taataggaag aaatggagaa atgattaaaa aaatacaaaa tgatgctggt
     1141 gttcgaattc agtttaagcc agatgatgga acaacacctg ataggatagc acagataaca
     1201 ggacctccag acaggtgtca gcacgctgca gaaataatca cagaccttct acgaagtgtt
     1261 caggctggca atcctggtgg accgggacct ggtggtcgag gacgaggtag aggtcaagga
     1321 aactggaata tggggccccc gggtggactc caggagttta atttcattgt gccaactggg
     1381 aaaactggac tgatcattgg aaaaggaggt gaaaccataa aaagcataag ccaacagtct
     1441 ggtgcaagaa tagaactgca gagaagccct ccacctaatg cagatcccaa tatgaagtta
     1501 tttacaattc ggggcactcc acagcaaata gactatgctc gacaactcat agaagagaag
     1561 attgggggcc cagtaaatcc tttagggcca cctgtacccc atgggcccca tggggttcca
     1621 ggtcctcatg ggcctcctgg acctccaggg ccgggaactc caatgggacc atacaaccct
     1681 gcaccttaca atccaggacc acctggccca gctcctcacg gtcctccagc cccatatgct
     1741 ccccagggat ggggaaatgc gtatccacat tggcagcaac aggctcctcc tgacccagcc
     1801 aaggcaggag cagatccaaa ctcggcagct tgggctgctt attatgctca ctattaccag
     1861 cagcaggcac aacccccacc tgcagctcct gccggtgcac cagctacaac ccaaacgaac
     1921 ggacaaggag atcagcaggc tccagctcca gctggacagg ttgattatac aaaggcttgg
     1981 gaagaatact acaagaaaat gggtcaagca gttcctgctc ctgctggggc cccaccaggt
     2041 ggtcagccgg attatagtgc agcctgggct gagtactata gacagcaagc agcgtattat
     2101 gcccagacaa gtccccaggg gatgccgcag catcctccag cacctcaggg ccaataataa
     2161 gaagtggaca atacagtatt tgcttcattg tgtgggggaa aaaacctttg ttaaatatat
     2221 ggatgcagac gacttgatga agatcttaat tttgtttttg gtttaaagta gtgttttttt
     2281 cccccccttt ttttttattt tgaaaatgta caaaataact atcactactg ataggaggtt
     2341 aatatttctg tgtagaaatg aaaattggtt tgtttttagt ctttagtgta gatgtacaca
     2401 ttccagcaaa tgtatttgca actattatgt ggtcgatgct ttgtgatata aatgtacttt
     2461 ttcaatgtat actttcactt ttaaaatgcc tgttttgtgc tttacaataa atgatatgaa
     2521 acctcctgtg tcggtaagtt ggatatgtgg gtaaaggatt catagtttct tagcagtgat
     2581 aaattaagat acatgtacac gaatatataa gctttcccca tgaattactg agtttttaaa
     2641 cactggcatg ttttttcccc tgttggagta tagtggtaga ttggaggttc ttttctgttg
     2701 tatttggcta tttcagcaca agtaatcctg atattttcat gtttttcctt ctatttgatt
     2761 aaaaactgca tgtgtataca atgatcttta gtatacttcc attgcattaa cagtgacatt
     2821 tccttttata catgagcact atttcagacc tgtaccgctg ctacaacagt taaccttcct
     2881 gttcttcact tatttccgag actgtttcag cataactaat tttgaacagt ttgcagacag
     2941 tgatttgagg agtttataag aaacattgtt tttttcatgt aaagcaactc tttccatgta
     3001 tatatatata ttataatagt gtgtttctct ctaaattcag gatagaaaag taatagaatg
     3061 tgaaagtata gctacattgc atctgccatt gaaacatttg gggtatgaaa atgttcaagc
     3121 tttttttttc tttttgcagt atagataagc tttgtcttgt aattgcacaa gtccagtcat
     3181 tgaatcaaat taattttttt atgtactgaa tcattttatt aatctttaac attcatgctg
     3241 aagttctgat attttgttga aaaccattgt tttactctgc atatttgttg gctctttgca
     3301 tattaatata ttagactaca tgcaaataca gtctgtcttg ccattgtctg ttgaagtgca
     3361 ggtttgatcc agccagtata gaactagctc tgtaggggtg aggaggactg tgctgtgtat
     3421 catccttgat tgtgttcctt caaggagcat tgcactgtaa gtacatcaga gtgacaaatt
     3481 gatgaactgc aacagtgtct ttttgtcgat gttccacata atgcaattgc tatattttgt
     3541 gtgactatta tgttggaata cagtgctgtc atgggaaacc ataactgctt cttaacatag
     3601 aataatacat agttctgtat tttttttaag tgagcttaat gggtaagtat ttttgatatg
     3661 ctttagctaa tagctaaaga aaattgatca gtaacaaagt tgaatagtat tatcagtgct
     3721 cctaaaatgc tgtttttcag tgtaaaatat gcctatcttt tatagtgata tgaaaaactt
     3781 gaaatgttta agacagaagt gcttttcagt ttgcaaagtt taaggactta acgccttttc
     3841 attaaatgtt agttctatca tctgtgggga gcaccatttg tatgaggaca aaaatgttga
     3901 ggttataggg cagaaaatag tacagctcat tgtggatgtt ttgaaatgtt ttttgattgt
     3961 tttatgtaac ttagtgactt cccttcccct tatttagatc tggatgcata gctctagtat
     4021 gaagtttaat agtaatagtt aaggccttac ctgttaagat cttaagtgta gggtattgac
     4081 atgaacagtt tcagtatttt gcatgatatt gttgcataga tgacctagga aagtgttgtg
     4141 gtgcatttag taattaaact gaaggaaata gttggattca gtatcataat tcacaaattg
     4201 gaggctgttg attttgattc gtttaaaatt taaaatcttt attaattgca aacagtgcaa
     4261 ttatttatac ttcacagtgc cttcccagac cttccacctt aggttctgct gcaaaaagca
     4321 acaggtaagc acaacctaag gccatctcta tataaatata tcagtacata catgttgtcc
     4381 ctgtgaggtt tgtggttgtg tactcactca agcaatctgc tgctgccgct gccccaaatg
     4441 tactttgtta tttatggtac cattctagtg gaaagtctgt taagttgttc aagcaactgt
     4501 ttacaatttt gggtgatgtt ttgtttttgg tttttttggg tttttttttt ccccattaaa
     4561 atgagtagat tgctgcaata actgaaaaac atccaaatct ttttgtgcac ccctcctctc
     4621 ccagagttat agaaatgttt aagaacactt cagtagttga gacataggaa atcatttggt
     4681 cagaaatttc aacagccttc acagcccgtt tgtatgagta acaggaaatt ctctttgccc
     4741 tccaaatctg atctttttat agttttattt ttattatttt tcccctgtat tagtactgct
     4801 ttaaagtaca gtaattcagt gagatcgttt tggttcagtt tcatagacag ttctattttc
     4861 atgacttgta tttgctgaca aggaagaata aagaatactg gcagtaagtt ttgggaaagg
     4921 catgtgcatc agtgaaatgt tacttgtata acaaataacc tttcataatc tgcataacca
     4981 gtagtttctg atttataata ttttaataac tgactgcatt tatttttgcc agtttaaaat
     5041 gttttgtgtt cttaggattg atgtttagtg catattttga gttaaatgac tatcttaaag
     5101 cagcaccata tcagttgttt ttattcattt tctaaaatgt gctgatccta ttaaaaactc
     5161 ctgcttatct tttacaacaa agaaaaatat tcaaaaatac tgccttcatt ttcacacaca
     5221 gtgctgaaga tgctgcaagc accaaatcat agctcataaa atcaggtcct gagatagtta
     5281 cccataaaga ggaatccttt gagtgtatgc cattggtgag ccgatgagca tggaccatag
     5341 aagggctcaa tgtagaaggt aaaattggca aatcataatt gagaaatatg actgtgttcc
     5401 catacataat atggtatagg gtgtaatgta cctgctcttg atcactttca ttttaaagtg
     5461 ctattcactt aaatgttcca tgaattgttt attgcaccac agtttgtgtg tgtgtgtgtg
     5521 tgtgagagag agagagagag agagagaaat aggtcagatc agtatgttgc aagcagatct
     5581 ttagagcctg tcaagttttg gttagttgta gtttccattt ggaaatgtag atgaatgctt
     5641 gtagatattg gagattgttt ctatcttgta agaacttttc actggtgctg taagcatttc
     5701 aaatagcacc agtcttaacc tttaaatggg aagtagaaaa ggtgagccca aagtttacag
     5761 atgattttaa tgctatacat gttagtgtag tgatacttag aatgctttgt ttgatgttta
     5821 tttcagaaat gcgtatacta gaaaatcatt ttaatattaa aactggtgac ttaatactag
     5881 ttgtaaagtg ttttcttaaa gaaggatctt ggtacttaat tgataaagtg ggtttagata
     5941 ggagtagcaa gtgctctcga tagagaaagt ttttgttcac ttcaatactt tgtcattaca
     6001 accagttctt cctgaaaata gttacatgtc tagtaaattg atgtagaatt aactcgctgg
     6061 agataatctc attttagttc tgcaaattct gcctggcttt aaaatgcatt ttcataatac
     6121 ttagaaataa tttgactgaa aataactgct tttttattta atcagtcaat caacttttac
     6181 tacaaattta attgagggat tttttaattt aattggtgct ttaaagaagc aaataaatcc
     6241 ctgggttttg ttttcttcag taaatatcct aaagaaactc tttaatgtat ttgcgagtat
     6301 atatatattt tcttatgcat gctcgatgca ttttcgtcct gagaaaagtg ttctctacag
     6361 aaactacccg tgtgttaaaa gaagattggc ttaaaatggc tactgtgatg ggaacagtgt
     6421 cttagggaga tgcagcttgg acttgaggta aattgaatac tttacaaact ggcttagagt
     6481 tttgctttaa tgtcattata tgtaaaaggg cacatgatta ttgtaatttt gtattcttta
     6541 tggtttcctt aattaaaata ataaatgtac agtgattact atga
//
