LOCUS       NM_177059               8266 bp    mRNA    linear   ROD 26-JUN-2024
DEFINITION  Mus musculus follistatin-like 4 (Fstl4), mRNA.
ACCESSION   NM_177059
VERSION     NM_177059.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8266)
  AUTHORS   Dos Santos,M., Shah,A.M., Zhang,Y., Bezprozvannaya,S., Chen,K.,
            Xu,L., Lin,W., McAnally,J.R., Bassel-Duby,R., Liu,N. and Olson,E.N.
  TITLE     Opposing gene regulatory programs governing myofiber development
            and maturation revealed at single nucleus resolution
  JOURNAL   Nat Commun 14 (1), 4333 (2023)
   PUBMED   37468485
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8266)
  AUTHORS   Al-Khindi,T., Sherman,M.B., Kodama,T., Gopal,P., Pan,Z.,
            Kiraly,J.K., Zhang,H., Goff,L.A., du Lac,S. and Kolodkin,A.L.
  TITLE     The transcription factor Tbx5 regulates direction-selective retinal
            ganglion cell development and image stabilization
  JOURNAL   Curr Biol 32 (19), 4286-4298 (2022)
   PUBMED   35998637
REFERENCE   3  (bases 1 to 8266)
  AUTHORS   Holzel,M.B., Howlett,M.H.C. and Kamermans,M.
  TITLE     Receptive Field Sizes of Nyxnob Mouse Retinal Ganglion Cells
  JOURNAL   Int J Mol Sci 23 (6), 3202 (2022)
   PUBMED   35328623
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8266)
  AUTHORS   Winkelman,B.H.J., Howlett,M.H.C., Holzel,M.B., Joling,C.,
            Fransen,K.H., Pangeni,G., Kamermans,S., Sakuta,H., Noda,M.,
            Simonsz,H.J., McCall,M.A., De Zeeuw,C.I. and Kamermans,M.
  TITLE     Nystagmus in patients with congenital stationary night blindness
            (CSNB) originates from synchronously firing retinal ganglion cells
  JOURNAL   PLoS Biol 17 (9), e3000174 (2019)
   PUBMED   31513577
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8266)
  AUTHORS   Lo Giudice,Q., Leleu,M., La Manno,G. and Fabre,P.J.
  TITLE     Single-cell transcriptional logic of cell-fate specification and
            axon guidance in early-born retinal neurons
  JOURNAL   Development 146 (17) (2019)
   PUBMED   31399471
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8266)
  AUTHORS   Sun,L.O., Brady,C.M., Cahill,H., Al-Khindi,T., Sakuta,H.,
            Dhande,O.S., Noda,M., Huberman,A.D., Nathans,J. and Kolodkin,A.L.
  TITLE     Functional assembly of accessory optic system circuitry critical
            for compensatory eye movements
  JOURNAL   Neuron 86 (4), 971-984 (2015)
   PUBMED   25959730
REFERENCE   7  (bases 1 to 8266)
  AUTHORS   Gu,Z., Imai,F., Kim,I.J., Fujita,H., Katayama,Ki., Mori,K.,
            Yoshihara,Y. and Yoshida,Y.
  TITLE     Expression of the immunoglobulin superfamily cell adhesion
            molecules in the developing spinal cord and dorsal root ganglion
  JOURNAL   PLoS One 10 (3), e0121550 (2015)
   PUBMED   25826454
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 8266)
  AUTHORS   Suzuki,R., Matsumoto,M., Fujikawa,A., Kato,A., Kuboyama,K.,
            Yonehara,K., Shintani,T., Sakuta,H. and Noda,M.
  TITLE     SPIG1 negatively regulates BDNF maturation
  JOURNAL   J Neurosci 34 (9), 3429-3442 (2014)
   PUBMED   24573299
  REMARK    GeneRIF: This study demonistrated that SPIG1 negatively regulates
            BDNF maturation.
REFERENCE   9  (bases 1 to 8266)
  AUTHORS   Yonehara,K., Ishikane,H., Sakuta,H., Shintani,T.,
            Nakamura-Yonehara,K., Kamiji,N.L., Usui,S. and Noda,M.
  TITLE     Identification of retinal ganglion cells and their projections
            involved in central transmission of information about upward and
            downward image motion
  JOURNAL   PLoS One 4 (1), e4320 (2009)
   PUBMED   19177171
REFERENCE   10 (bases 1 to 8266)
  AUTHORS   Yonehara,K., Shintani,T., Suzuki,R., Sakuta,H., Takeuchi,Y.,
            Nakamura-Yonehara,K. and Noda,M.
  TITLE     Expression of SPIG1 reveals development of a retinal ganglion cell
            subtype projecting to the medial terminal nucleus in the mouse
  JOURNAL   PLoS One 3 (2), e1533 (2008)
   PUBMED   18253481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL662855.19, AL662836.7, AL604002.8 and AL596382.12.
            
            On Nov 18, 2022 this sequence version replaced NM_177059.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK046350.1, AK081114.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               AL662855.19        110965-111190
            227-362             AL662855.19        120143-120278
            363-396             AL662836.7         5845-5878
            397-642             AL604002.8         72668-72913
            643-836             AL604002.8         141011-141204
            837-960             AL596382.12        4730-4853
            961-1127            AL596382.12        66364-66530
            1128-1248           AL596382.12        81219-81339
            1249-1410           AL596382.12        94872-95033
            1411-1545           AL596382.12        95354-95488
            1546-1572           AL596382.12        96748-96774
            1573-1691           AL596382.12        98091-98209
            1692-1841           AL596382.12        100508-100657
            1842-1949           AL596382.12        109254-109361
            1950-2059           AL596382.12        116973-117082
            2060-8266           AL596382.12        118578-124784
FEATURES             Location/Qualifiers
     source          1..8266
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 31.86 cM"
     gene            1..8266
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /note="follistatin-like 4"
                     /db_xref="GeneID:320027"
                     /db_xref="MGI:MGI:2443199"
     exon            1..226
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            227..362
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..2762
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /note="follistatin-related protein 4; m-D/Bsp120I 1-1;
                     follistatin-like protein 4"
                     /codon_start=1
                     /product="follistatin-related protein 4 precursor"
                     /protein_id="NP_796033.2"
                     /db_xref="CCDS:CCDS24673.1"
                     /db_xref="GeneID:320027"
                     /db_xref="MGI:MGI:2443199"
                     /translation="MKPGGFWPHLALLGVSLPAVLGWMDQGASRSPNMVPGESQAEET
                     RGFEVTRREGLPSPGLSASCGKKLCSHGSRCLLNRTTGQPSCQCLEVCRPRYMPVCGS
                     DGRLYGNHCELRRAACLLGKRIVSVHSKDCFLKGDMCTMAGYARLKNVLLALQSRRQP
                     LPQGTPRQSLASQKRLLVESLFKDLDADGNGHLGSLELAQYVLKEQDMDGSLNRCSPS
                     DLLRFDDYNSDGSLTLGEFYTAFQVIQLSLAPEDKVSVTTVTVGLSTVLTCAIRGDLR
                     PPIIWKRNGLTLSFLGLEDINDFGEDGSLYITKVTTVHMGNYTCHALGHEQLVQTHVL
                     QVNVPPVIRVYPETQAQEPGVAASLRCHAEGIPLPRIIWLKNGMDVSTQMSKQLSLLA
                     NGSELHIGSVRYEDTGAYTCIAKNEVGVDEDISSLFIEDSARKTLANILWREEGLSVG
                     NMFYVFAEDGIVVIHPVDCEVQRRLKPTEKIFMSYEEICPRVEGDATQPCQWASAVNV
                     RNRYIYVAQPALNRVLVVDVQAQKVLQSIGVDPLPVKLSYDKSHDQVWVLSWGDMHKS
                     QPSLQVITEASTGQGQHLIRTPFAGVDNFFIPPTNLIINHIRFGFIFNKTDPAVHKVD
                     LETLMALKTISLRHYGCMPQAMAHTHLGGYFFVQCQQDTPTSTGPQLLIDSVTDSVLG
                     PNSDITGTPHVSPDGRFIVSVSNKGPWLHVQEVTVRGEIQTLYDLKINPGISDLAFQH
                     SFTEGSQYNAYATLDKEPDLLFLELSTGKMGRLKNLKEPPRGPAPTWGGPRRVLRDSG
                     LFGQYLLTPAQESLFLVNGRQNALRCEVSGIKGAATVVWVGEV"
     exon            363..396
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            397..642
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            643..836
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            837..960
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1127
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1248
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1410
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1545
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1572
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1691
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1692..1841
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1842..1949
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2059
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..8266
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8249..8254
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /note="hexamer: AATAAA"
     polyA_site      8266
                     /gene="Fstl4"
                     /gene_synonym="B230374F23Rik; mKIAA1061; SPIG1"
                     /note="major polyA site"
ORIGIN      
        1 agaaataggg cagccgcggc agcggtggca cagcggcggg cggcggaggc tcggagagct
       61 ggagcttgga ctatctctag cacgccaggg gaccagccga cagccggaga cgacccagcc
      121 gaggacgcgg ggtccgggtc gccgcctctg tcgccgccac ggggcgctcc ctcccttcca
      181 cccgagtccg gccacctggt cattccctcg gccccggccg ccgtagactg gacaaaatga
      241 aaccaggagg cttctggcca catcttgccc tactcggggt ctccctgccg gccgtgctgg
      301 gatggatgga ccaaggagcc agcagaagcc cgaatatggt tccaggagag tcgcaggcag
      361 aggaaaccag aggctttgaa gtcacaagaa gagaaggtct tcccagccct gggctgtcag
      421 cctcctgtgg gaagaaactc tgcagccatg ggagcaggtg cttgctcaat aggacgacag
      481 ggcagccctc gtgccagtgt ctggaggtgt gcaggccccg ctacatgcct gtgtgtggct
      541 ccgacgggag gctctacggg aaccactgtg agcttcgccg tgcagcctgc ctgctgggca
      601 agcgaattgt cagtgtacac agcaaggact gctttctcaa aggagacatg tgcaccatgg
      661 ctggctatgc tcgtctcaaa aatgtcctcc tggcactcca gagccgcaga cagccgctcc
      721 cacaaggaac ccccaggcaa agcctcgcct cccagaagcg cctcttggtg gagtcactgt
      781 ttaaggactt ggatgccgac ggcaatgggc acctcggcag cttggagctg gctcagtatg
      841 tgctaaagga gcaggacatg gacggttcac tgaacagatg ctcacccagc gacctcctgc
      901 gatttgatga ctataatagc gatggctcct tgacccttgg agagttctac acagccttcc
      961 aggtgattca gctaagcctc gcccctgagg acaaggtcag tgtgactacc gtgaccgtgg
     1021 gcctgagcac agtgctgacc tgtgctattc gtggagacct gaggccacca atcatctgga
     1081 aacgcaacgg gctcactctg agcttcctag gcctggaaga catcaatgac tttggcgagg
     1141 atggttccct gtacatcacc aaggtgacca cagtccacat gggcaactac acctgccacg
     1201 ccttgggcca tgagcagctg gtccagaccc acgtcctgca ggtgaatgtg ccaccagtca
     1261 ttcgtgtcta tccagaaacc caggcacaag aacctggggt ggcagccagc cttcgatgcc
     1321 atgctgaggg catccccctg cccagaatca tttggctgaa aaacggcatg gatgtctcaa
     1381 cccagatgtc caaacagctc tccctcttgg ccaatggaag cgaacttcac atcggcagtg
     1441 tccgctatga agacaccgga gcatatacct gcattgccaa gaatgaagtg ggtgtggatg
     1501 aagatatctc ctcactcttc attgaggact ctgctaggaa gacattggca aacatcttgt
     1561 ggcgggaaga aggcctcagc gtgggaaaca tgttctatgt cttcgctgag gatggcatcg
     1621 ttgtcatcca ccctgtggac tgtgaggtcc agagacgctt gaaacctaca gagaagatct
     1681 tcatgagtta tgaagaaatc tgtcctcgtg tggaaggaga tgctacccag ccatgccagt
     1741 gggcctctgc agtcaacgtc agaaaccggt acatctacgt ggcccagcca gcactgaaca
     1801 gggtccttgt ggtcgacgtt caagcccaga aggtcctaca gtccataggt gtggaccctc
     1861 tgccagtcaa gctgtcctat gacaagtcac atgaccaagt gtgggtcctg agctggggag
     1921 acatgcacaa gtcccaacca agcctacagg tgatcacaga agccagcact ggccaaggcc
     1981 agcacctcat ccgaacaccg tttgcaggag tggacaattt ctttataccg ccaacaaatc
     2041 tcatcatcaa ccatatcagg tttggcttca tcttcaacaa gactgaccct gctgtccaca
     2101 aagttgacct ggagactctg atggcactga agacaatcag cctacgtcac tacggctgca
     2161 tgcctcaggc catggcacac acccaccttg gtggctactt cttcgtgcag tgtcaacagg
     2221 acacacctac ctccaccggc ccacagctgc tcattgacag tgtcacagac tcggtgctag
     2281 gccccaacag tgatatcaca ggcacgcccc acgtgtcccc tgacggacgc ttcatcgtca
     2341 gtgtctccaa caagggcccc tggctgcacg tgcaggaggt cacagtgcgg ggggaaatcc
     2401 agacgctata cgacctaaaa ataaacccag gcatctccga cttggcattc cagcattcct
     2461 tcacagaagg tagtcagtac aacgcctatg ccactctcga caaggagcca gacctgctct
     2521 tcctggagct gtccactggg aagatgggca ggctgaagaa cttaaaggag ccacccagag
     2581 ggccagcccc aacctggggt ggaccccgca gagtcctgag agacagcggg ctctttggac
     2641 agtacctcct cacaccagct caagagtcac tgttcctggt caatgggaga caaaacgccc
     2701 tgaggtgtga ggtttcaggc ataaagggtg cggccacagt ggtgtgggtc ggggaggtat
     2761 gaaagttggt aaagaaccac cctcatcctg actccgcagc cccaaccagg cgcgctgtac
     2821 attttcacag acaaaaacaa aaacaaaaat acaaaaaata caaaaaaaca aaaaacaaac
     2881 aaaaaaacaa gccaaaccct gtacttcgct ttgtggttca acactgatct ctgtgcaagt
     2941 tccctagtat aagatatgtg ctgcaaccaa gattgggtgg ttttcatcca gaagtatgat
     3001 ttaataccgt gagctatgat gagaacacac actgcttgtg tgcaggaaag tcatctccgt
     3061 gcccggttgc acaccgtgtt gcctggggga caccacagaa ccgagggatc ctgctgccca
     3121 ggctgacact tctgtcagtt gccttcacgt agtcattatc ataacctgcc cagccccagc
     3181 cagtctgtgc cctggaggat tggcctgagc agcaggctgt ccctctcagc gagctaacat
     3241 accctgcctg ccaggaacct cacttgagcc attaactgat gctgtttgct tgctttccca
     3301 tctgaatgct atctccatga gggagagcct ctgagactta ctacaccttg ggggatgggg
     3361 aaatcactct ctttattttg gaattttttt ttattaaaac tagttggttt tttttttttt
     3421 ttttttaata atctcagatg ctaggaggca gatagatgct ctccaaggtc ctgataaatt
     3481 attcccatcc ttaggcgaag tctctgaaga gaaagggttc caatcttaca tgagcagaaa
     3541 acaaaatgat atccaagaaa cagaggcact ccacaccatt gtgttgttga ccatgtacag
     3601 cccataccac catggtaaaa atctatgcgg gaaccccaag agaccaagct gaggtttcac
     3661 catagaaagg tattaaggaa gcctaacgta ccagcagaag tccagaccca gggcagacca
     3721 ggcttgcctg gcaagggata ggcagtctct gggctcagtg ccaaaatcta gaagccacga
     3781 gtgccatcca tccagagtcc taaggctgtg tttctgcaca agcagttggc actaatgcct
     3841 cagccactgt caccacactg caagagagcc ctgttcccta agtgttctca ttcccacact
     3901 ctaagctaca cagtctccaa cttgcagaac ctacaaagga ccgtgtcagt ccctcctctt
     3961 cctgccttca gtatgctctc aagccatcag gaagaggcac aacccagcca gctctacagg
     4021 gaccacctct gtccgagccc ctcagcaagg agagccccta cccaggtctc cccaaacact
     4081 cctgtccact cccatgtcag tggtcaaaat atgcctgctt tctagcttga ataatcattc
     4141 tgcaaaccct acagcattaa gacagtgggt ctacccccac ccttcagcta ccttagctac
     4201 ttcatctacc aacaatggcc gtgactttga aaacacagac tgtacttcat tcctgcttcc
     4261 tgtgtaagta ctcaattgcc tgtgccagtt tactgccact agtccagcct gccccacatc
     4321 tcctgtctct cagtccacta aacaactgtc ccttacagtc cccagtagtt gtctgtatat
     4381 gtgctatcat gtttcagatt tgggtaacga caagacacat agaggttgaa gatgctgacc
     4441 tcagaggcct aatggtcatc ttcacacctg gggtggatgg tgacgtattt tatctgcctc
     4501 agtatcttga tatgatcccc agagtcctat gttttcatta aaaccttcca atgtttgtaa
     4561 tttttttcct tttgaaagaa tagtgcctgc ctctggcaga agaatccctg agcctaagag
     4621 gcagagcatc accacacaca cacacacata cacacacaca tatcccacca aggccagagc
     4681 atcatctctc cccatcccac caagaccaga gtacctatcc tctttggatg caggattcca
     4741 gaatcaaagg ccagtctgtt ccaccagact ggatgaaagc aggggtgcta cttggccact
     4801 gtctgtctgt ctgtctgtct gtctctctct gtctctctct ctccctctct ctctccctct
     4861 ctctctctct ctctctctct ttctctctcc atatacctgt aaggcaccca cacatttttc
     4921 tattcttctg gtagaattgc cggagaaagc caccatatgt ctagtgacct gcatgcagga
     4981 cttagttaaa ttgagaaatc acaagtctga gacctactct gatgtcagta gctcagccca
     5041 gggcacagcc ataaaagtgg agtggcttcc tgtagaggaa ggcagaggac tacagagaaa
     5101 tcttcccctc tcttcattgt gggcccagaa gagactccgg aatagagttt aaatcccaat
     5161 agtggaaggt ggtgacacaa gtgagtctcc tgccacaagc ccagcccaac gggttgttct
     5221 gaggaacaca aagatcaaca gctaacagtt tacccaggga ggattggttt aaccaacaaa
     5281 atcaccagga aagctatttc tataaacccc atctgtaatt cttaacagtc aactaacatc
     5341 ataaacaccc agccattctt ttctttccag aaaacaaaca caaattctct gcatctgtag
     5401 ctcctggttt tccttctgcc ccaaagtcct ctttcttaac atcctaccca gccacccatg
     5461 agtgcatgga agagagactt cctgcttctg agtctgtgac cctcctgtct aaacagacca
     5521 gagggtaggc aacccccaat atgctaaggg aatctcttca gtccccacat cacacaaata
     5581 tcctgctgcc ttcctggatc ccgggaggag gctgggaaag gcctgaagtc atggctggga
     5641 tcaaatactg atgcagagct gcaggttctt tgatgtggag agagagagta tcaccagaga
     5701 agttcagtct ctctgctgca taccccacca cacactgagc tatctccccc tccacctgct
     5761 cctctgttga ggaaagggct cccaactgaa ggggctcacc ccaggaaggc agctcccacc
     5821 ccaaacaaag ccaagagcag cagcttgctg ccatgaggca tgggaacttc cgaatctttg
     5881 ttcagctaag cagccaggag ttggctttgt acagccgcat cttcttgttt gtctgttgac
     5941 caataacctg tgaactaagg gagatctcag aactgagatg tgaaacagat tcgctctgga
     6001 tatatttttg taccacgggc taaagtgtag ttgcttcatt tctttttcat gtgtttcatc
     6061 cgagtaccac tgatgctgaa ccatctccta ccctcccaga agcctcctgg agaattgtca
     6121 ccactgcccc tcccctctgc acacccacca atctacctca catcttcctc ccaggcaccc
     6181 agcaccccca gaatgccacc ccaggaggcc aaaggtgaca gaagactacc gtagcacgga
     6241 ctcagaagtc ctccaccaac cgcgccccga gtcccactcc atgtgtgacc agaacccact
     6301 gggaccgcac cttgttgtcc agaatcacag cccagaccca agctctcatc tctacaggct
     6361 tagaagccga agactaggga aaacaccttc agagtggcca gaaagacgga cctttgtcca
     6421 acagtgacag agctggtgac atttcatttc aaccccgtct catgctaagc agcccacggg
     6481 ctccgacctc catctgctcc cgcttcactc actattcctg gttccctccc tgaatcccaa
     6541 ggcccctgct cctgagatct cctagaatgg ccctcatcct tcaaggagca acaaccctct
     6601 actgcaccag cttcatgcat cctttgccca caacgctcct tgctttgagg attcaagtga
     6661 gaagttactc acagaccaga agttactcac agaccacttg caaccaggcc acgacagaga
     6721 caaactggat ttcttcaaga acatcactaa ctgccttcat tgggttttta ctccacaacc
     6781 acagagatgc tcagtgggac acttaaaaga tccaacagga gcagggcaca cagggtgtga
     6841 ccacaagatg ccacatggct ggtggaaggc gacatacttc ctgcttactg ctctagctgg
     6901 aggacctgtg tgtctcggct gagcctgtgg acttggacat cagctcccca gcagacgcct
     6961 aaagattata agtgagcatc atcctagtcc tccacagtct cctttggctc tttgggtatc
     7021 taattacact ttgaggaagt atcatttaac caaacacaat gggagaaatt atgggatgta
     7081 tagggagaga agaaatggac ttcagaattc gtagtgaggc tttttagcag gcaccagcgc
     7141 atttagaatg tttttgcatt ttatatgaag tcacaattgt gcacctttct ttccaagctc
     7201 aactttacga ccagtgacag tccatgtccc atggcttacc ccccccacag ctcccaccaa
     7261 tcaaggagca tctgcctgct actgtctcgg catcatgttg cctccactca tgacgcctta
     7321 ctgctttagg gttccaatga aaagtcactc atggcctagg gaacatggcc ctaccctaaa
     7381 caactctaga gaacctggcc tacacgcaca aagccttgtg tatgaactga ccctctacac
     7441 caagccttgg tgtcatgttg ctctccaaag ttcaccttct aagaaaggga aaccagcctt
     7501 gaatggctga gagatgcagg gctctctaaa ctctaaatcc ttatccactg ttgagcacac
     7561 catctctagg gatgggagag aaacaagcct ataggaggtc agccccagcc cactgtgccc
     7621 cacgatggta gcgccccgta ctcacaccct ccctgcctgc ctcctctgcc ttccctccat
     7681 agctccccat gttccccagt gatgctgccc tgcttcctga aggctgtgta aaaataaatg
     7741 acccaaagtg aaactgggca tgaagttttg ctggagtggt cgcacattgt ttcacgctat
     7801 tgtgctgcca aatgaccctc aagttgtgga tccccataca ccatcaagag agtcatcctc
     7861 tccccccacc tcagaaaaac aaaaaaacca cctttggatc tcttacattg aggcaggtta
     7921 cattcttttg agcagttgtg tagactccaa aatatatttt ctgtaatcag tatttctcaa
     7981 aaggccacct gtaattatta atacacatgt gaatttttcc ttatttataa gatatatata
     8041 aattattttt aatacatcaa ctttagtaga aatttgtacc aacccagtaa ctgtatgtgg
     8101 catttgaaat aagtttgtgt ttctgttggt gtgtgacatt gtattgaaca cacgctgcat
     8161 ttaccgcacc acttggcaaa agaaaaaaag actcacagat tatcataagg gacggtcatt
     8221 gtcgatgctc tttttctgag gattttacaa taaaacttga aaaaaa
//
