LOCUS       NM_001370266           21110 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus fibrous sheath-interacting protein 2 (Fsip2), mRNA.
ACCESSION   NM_001370266 XM_006500496
VERSION     NM_001370266.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 21110)
  AUTHORS   Fang,X., Gamallat,Y., Chen,Z., Mai,H., Zhou,P., Sun,C., Li,X.,
            Li,H., Zheng,S., Liao,C., Yang,M., Li,Y., Yang,Z., Ma,C., Han,D.,
            Zuo,L., Xu,W., Hu,H., Sun,L. and Li,N.
  TITLE     Hypomorphic and hypermorphic mouse models of Fsip2 indicate its
            dosage-dependent roles in sperm tail and acrosome formation
  JOURNAL   Development 148 (11) (2021)
   PUBMED   34125190
  REMARK    GeneRIF: Hypomorphic and hypermorphic mouse models of Fsip2
            indicate its dosage-dependent roles in sperm tail and acrosome
            formation.
REFERENCE   2  (bases 1 to 21110)
  AUTHORS   Brown,P.R., Miki,K., Harper,D.B. and Eddy,E.M.
  TITLE     A-kinase anchoring protein 4 binding proteins in the fibrous sheath
            of the sperm flagellum
  JOURNAL   Biol Reprod 68 (6), 2241-2248 (2003)
   PUBMED   12606363
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL845500.6.
            
            On May 4, 2019 this sequence version replaced XM_006500496.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments, and were inferred based on partial
            transcripts.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849384 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               AL845500.6         109569-109735
            168-293             AL845500.6         110005-110130
            294-455             AL845500.6         112791-112952
            456-545             AL845500.6         114134-114223
            546-685             AL845500.6         115324-115463
            686-827             AL845500.6         116816-116957
            828-938             AL845500.6         117579-117689
            939-1062            AL845500.6         120870-120993
            1063-1149           AL845500.6         124566-124652
            1150-1265           AL845500.6         127659-127774
            1266-1302           AL845500.6         128633-128669
            1303-1406           AL845500.6         129215-129318
            1407-1470           AL845500.6         131349-131412
            1471-1528           AL845500.6         133707-133764
            1529-1562           AL845500.6         138971-139004
            1563-10506          AL845500.6         140774-149717
            10507-20165         AL845500.6         150304-159962
            20166-20660         AL845500.6         163899-164393
            20661-20752         AL845500.6         165697-165788
            20753-20799         AL845500.6         167511-167557
            20800-20843         AL845500.6         171138-171181
            20844-20913         AL845500.6         173409-173478
            20914-21110         AL845500.6         174676-174872
FEATURES             Location/Qualifiers
     source          1..21110
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.08 cM"
     gene            1..21110
                     /gene="Fsip2"
                     /note="fibrous sheath-interacting protein 2"
                     /db_xref="GeneID:241516"
                     /db_xref="MGI:MGI:2664111"
     exon            1..167
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..21050
                     /gene="Fsip2"
                     /codon_start=1
                     /product="fibrous sheath-interacting protein 2"
                     /protein_id="NP_001357195.1"
                     /db_xref="GeneID:241516"
                     /db_xref="MGI:MGI:2664111"
                     /translation="MELYLSACSKTANVAANKAASSTVAEDSQQCVDGRHKTPIPGVG
                     AAQLLDLPLGVKLPMIPGTDTVYFTTNISEKLFRPSYGFNLSDPYCRLLETQYKSLHD
                     PHLRTYYKRKDILRRLKKGGYITSNNKIVCSLRELNKYRQYLTSLKLDFERNYLREQQ
                     LISKQLHKLQETSQLPHCSDVTRFQNWLLQDNTHSIKDQERLLRHRYLDMISKELEQL
                     ERTAEEQRLLRIDRDERRQREYTRKKLTLRRKIEEEWKTKEMMLLTKIGEDVKREQKI
                     EEQRRKSREESDRKKQAMLEKKMAYHLQKMQDTGLKDDIGRNGFDYRGQNGTTFESSS
                     KKRKKQFDDIKIVYPDGDQKAYRGTSGQVSATVNQSQSSSKDVTKVSASSVTYPAEVQ
                     NSSSEQKRSEVTKRLSDERDPGTTSARESIISTQLSPTRNAKLSQISLDHQKEEKEMK
                     STWNGGLSKKSSYAGEPGSPTDAPPQGIFSFPVNSNTQQNLQHCLKDKVTSEELNSII
                     QNIMTWVVATVTSILYPAITKYEERVQNNTYPVTDDSDLSSDSSSFCSTCSEGFTYRN
                     YTAKTLPVDPCTFASDMPIKKPPTPLKPPSAHVERTVIDQTYQRQGQSVPSQVNYQKT
                     SLDYQFPKIGSSKSDSHLLTSLETCTKKSKDATTETESLEISLLYDKKAKAMDQIKNL
                     KNVFVNFKCHLKGETQLILESIFQEIMSDLSQAIPSLSSVTAEVFVDQTETEREELLS
                     NVDICSVASEIVENMLEKLESAVEKRCVQMFSQEDLSVDIKPSLSTSGDYLSSVETKP
                     SEETLSYTLEPMCDVADDMVHAILEKLMILASYKKNDVPPEDTTKHFQQTKTEPIHKV
                     HQQTEQKKASFASDPANQIVKEEIQSLISSIFSQSSLVGYVEEAISTILGYVQTELNN
                     ERLIASEETVVLLQLLDDVLTQLHQQPVKAGVKKPRRPRVRNLSDPEEKYRVTGTRPF
                     NNLKSKRPFPPVNVPGMVLYSEDDDEEIDNFVQSVLDSSFNDEKSSSQEQVPNYWPKK
                     RDTYFESKRSNKLPTKSTFQNKVGSHDWGLKLELSLSSEDIVKTKHCLGQEPSIFSQD
                     QKHQIQKASENIVKHILTDMLKDMSSDSSSHLGSQTGKGASAFISEKSQGLSDQEWME
                     QMFSVSEICAFAHEITDSVINILHKASMHIPNTIKNAFTSVHPTHVAPFDTAHTSKET
                     PSKMPFKVWFDSEKKMKYLSSLNMEHEKTSQLRSGKCEPKRVNDITDKITNTIFKRLK
                     LFVCPKLQIGNKSSLIEKSLHSQLSTYTMKIVNIILHAIQSELEINKTKPNLKETDHP
                     KCHKNKGWFTDPNKVVESRVTSVNDDIMESPLLTCICEMISSTNEDKKNTSTYTDKTL
                     STSICESGNFHKQSILSNKQDKNSFCQLLAKPCLQHSLADEKDFKVSSKLEVLDQIGD
                     TLHEMLGKLTGDHPDPQPSCSHQNTETIDKDPPTMSNTQLISKAILENVLAKLCDVDI
                     DTSIVNSGPKTVPESLDIDNLSFASTMEEMAKCTNIISNIISKIMKDNKEVTKSKAKN
                     DLPTSSKTEIPKEMCPQNLKNIASDILNMVFAKLEHFASGSVVNVGNLNDENKKEHTV
                     DWECESNSSPADSHDKSLQSTLYSHAKKVSNGILKAIQTELNMNPPDCKTDKKRSPEE
                     TQILTNIVDLILDVVSSDMFAEPESENQSNENYGYRPTYGNFLPGGAESDSFLDDDTQ
                     NKELIRDATSFNEETRTLSTDQMGLERTLSKIEVKLKEPHRSPIVPIIRNILNEIFQS
                     ALINQLNVFSLSRAHFSGMPQNAPTSSTQTSAHFMDQMMGPLVSDTDVSIVVNDVVRT
                     VFHKLYSAAMTERHVSENRGKTIILSANVSFRECTYGGNAPVSGLNENVCDLQSSWNV
                     DKQIKINVVEDIVQAILGNLETFAASKVESLFCPQVKFTVPVTLPVMQEEGSLSQALS
                     GKDSYSDNQLPCLVDHGNPEQMDSWYQMSLSKLNIYAKDVARKILQGIKHELDKEQES
                     PLLTNNIVVSENIASQVVNKVLDIVSCKSKCDKKSSDKDHYSEQQVGIIEQLVNKREY
                     RKILEFQIQDTIEGILCDIYENILYQNNLSFATPTLKYGIPAKHSEANFEQVVMGTNI
                     IPKVSVPKADVILVSKDIVDIVLHNLTSLVVLAINAKDSAPARVAIYDIFPKPQFQQP
                     LSITQRTEETPGHFSHSKNKNLGSPDVYQVPVNGKEDTKELAPDPCKENANRITQPIF
                     NRLQSFATERINSLMTPAFQSKGNVFVSPQFEIGKDDNCIFHEPGQAESDVDVLKLTT
                     RTVTSQELVEPIFTSCRENFGTTPHLSQTNLKDYAAFIASTILKLIKNDLDLEVQSMH
                     TYSSHILFQKNMIVSEIVNNILKILPNKEPIKEFFLSSPENSSCSQLTISSEDLVGYK
                     EKEKATALPQFTNDSLEENQVTVEKESQRDVLEEIFMRKGESKPREKTEILRTVEEVL
                     KKLSQKIMEIIGHVAPFNESPHTVSKSKSKTAAATQKKFFQSRINNVSNDILENVLSE
                     MHSVVVTSLYRNNKSKREGEMHDSSDSSSVKPSGSRETKPTRKRSSPLRLGVPQMHPH
                     ADNLNALVLENTILPYSPLQIGKYLVQIVLENLSNFVSLHLEEGYPPEGSYDDLYLLR
                     LHNAKLSPKNSPRPGGKASLKMRSKINSLSKFKTKPHLGISSTKTKIKNKLSAGEKTP
                     RESRSKTALGLPQTPQVEDTKTTLKTKLPVAELRLYATNIITDILQVILSSLERAAQH
                     RAMFNTKVLASSQILEASKIVNAVLQELYATNNDNLASPINISSLSDRRLSKQNLGAG
                     YPTEQPCFYLENVSSQLEQIFPKEGILKKMFDKWQTETSDTETEKSKLLTIAENILTE
                     ISIKAKDLEYSLSLLNLPPLEECENRLYDRFKGVSTRAEDTNAQINMFGREIVEMLFE
                     KLQLCFLSQMPTQDSNGILTSRKEHGTSKSKHGVPTKPILGGIQTYNSKMADQVSMSP
                     SNQIVHEIVERVLHMLESFVDLKFKHISKYEFSEIVKMPIDNLFQAQQRQLSKKMLPK
                     LPFRKFGDESKPGTIISKDDGQNTLLQVHLFHSELLTYSVTAVSGMLRIIKNKLDKEI
                     SQMEPSPVSILKENITASEIIGTLIDQCSHFEESLIKNLPTKHWFQGTENVYIVNQVE
                     FATPVKMPPSNTSDTPRTRRSSQGSVSGMGFSSEDDMKEKYSVTSNSSSHISSCVENT
                     NKSLEPMGRSNSEAMPSGSRHKAHDHGQRKPNFTPFEQVTKTHNFLPQGSVLQKLFKK
                     VNDSTEESLKQVLSFIETGKRENPRVFHYETTKSAEPNEIKTTAPPLKICLAAENIVN
                     TVLSSYGFPHQPNTNESTETMKPFFMSRQIPLSEVCEGQKDTEKTLLKTWYSRKALIQ
                     EEESEGLEACQEDFSLLHKWKNKKPQMTTETVEETKTIVFADHELGPNEMHLVARHVT
                     TSVITHLKNFKTGVSTEKFSHVSSLSKKIDDANQPLISIYSNSSVCQFCEHLSDAVIC
                     YLFLNISDGIKKCSREKAWEIQDAIIDKNVIIHSQLYKTRSISIGDLALSIFEVIVEV
                     LANRNMINADKAHQASIKAKYMFCPGVTSSDFDDIFQDLLKEVIFVLSKILGINHFEN
                     NVRNKSYPTLKNNLPVFNKVNTIENQIGPRKLESSPPLTDQLAQKNKLNYLARRLNSL
                     VGSLRSRESKEVVNEVFNIVLDLFLPDEIPDGDLSSGKLAKTFSSSNNQPSNRSLANN
                     VGLSPKSIFLLNIVCEKLIRTLLEKCMGGTPFFEDSSLFREIPEECQHVKVLPSVQGG
                     GFDYREAPMDCEQFQGDYMSELLENLADVDQDLLSSDCILNVISHSLVKSLMDKLSHG
                     LQQAPFENKYRNYRTREMQPFITKAKRQELIEPEETKGHVGFMSYDNNFLTKSLNNTN
                     ANSFKKHTQFGKKHAGKSISLSFSDGKESRGINTACFHKLCQRGVNGGVFSATFLEEI
                     ISELFYNLSTSLWKKNPNITEAWLNEINTLLINNVVKKLNDAEITVLRYPEERLYFPS
                     AHKGCIAKIVDSIYYDVLQQYEFTVTCGGNLPYDNTPVAKRISNSILLEVIDYQLPSC
                     FKGKLRSNLYHTLNAEIILYKLHNSLKNFNSEPMTSKDYSTMLPHSFLEYVIRRVLAQ
                     LISLPIKSSSLEKKYLASSDFNEMSNCITNKVMSAISKHKIWLTIYDNQCLYTDKNLQ
                     KMVDSVYSNILQMSSSVDSIQKNIISRSPIMIDQIASFIIQEIIENHLQPFLCGERLP
                     RPKTPLDEVSYMVKQVLSDVVESHKSQKPSPFGIYPDKLVGETVTRVLSKIFSPNTNI
                     NVELENVTQKIVSSVHKHLDKAKIPILCHKQPPFPFSNTDIVDELVTSVYKNVLKQHG
                     LDPDIDESVNGEVFVENITKLITAAISDYLLHPLFSGDLPAASCSNSVTDHTVYDILG
                     DINKSSKPNQTLPLYNTLLPYTFLEDMIRVLLSKFFPSAPKIDSYKAASKDKEGVNFN
                     EIASNLISDIRRKISQHEIRFSKDEDKTKSFYSENDVQHLVDAVFMNILENYGSPESV
                     EQNITKSNDVFIDQIAGFIIKYICEHHLQPFLERKQLSTSSYKYSDDDRQDLLYGSAY
                     SSTFLEDVVSGVVSKIFHRVIGIVQVNSTINSENILFDKAENLIYWITEEFSKAQVTT
                     IENAEERLSLSPVEGNILQKIIDTVYSKILEEHEMEIMPNKDFLNDTKALASQITEII
                     LSEISYFQIPPDLVANLPLRLHSKLSQNVLVNKVHYDISKSRFRRQASTMYTTMLSHV
                     HLEKIVTQLMSQINPSDSSVGHSDTYQSELSNTVVKLINEIMSIISKHAICIVKHGNE
                     KQSMISEKEMQSMVDSIYADLSHSNLYQSLTKDKKGLSSIPVSKIANFIIKEIFNHHL
                     ESFLSGDKSILSASVAQTCKKKATTSTKQRELSFIVNSAVFLEEVITELLCKILQTFI
                     QNSLSMETPERAIAEIMDIVTTLVKSIVFEFTSSEILVAEHLDESLWFSETYKEMVQK
                     TVNSVYGNIFYEYKSLTQLHRAVQYDTSGFGGKMYHFLLEEMYDYQVQSLVSGELMPS
                     CYASPQSANIIKNVLNVILKDTNALPSCITVLPCSLIENMIYKLLENIFPSDDTTNEL
                     KKEEKEEAGPDDVDEFMAAASKLTDEIIQEISEHEIRFANAEDTASMIYETTENFIDS
                     VCNNILKNSEFQAEVQKDAHKKGGSFLSKIAGSIIKEIMDHYLQLFLYGEGSHSSKLP
                     HFGGASVVAKSGKEKAPSSLFSAAFLEDVIVDLAHKFCSFLTLTDDARKKDLPEAEIV
                     SLAIKFANSLIRDFRKSGIKVLPHAEEIFSFPPIAKETIDEISNFVYDQFIGKLGADG
                     IQKDGTGNMVIEMVSSLAQKAISTFKIQPLFSGDWCSTFFSFLDAENISQRVQLLPKE
                     TSMQISGALKQNQLALSKITSIKKDDTQDPILNSIATIMKSNIINLLSGPSAGVTDAK
                     KEDESKVKPATRETTSPPTSPPATMKSQGSQVQQLATSPPTSMKSQRIQVQQSVMSPP
                     TTMKGKGAQVQQFATSPPTSMKSQGSQVQQSAMSPPTTMKSRGAQVQESVTSPFTTKE
                     SRGAQVQQSAMSPPPSMKDRGAQVQESSTSPPTTMKSRGAQVQHLSSKYKGNETGKEN
                     LVLVNEQGQILEIFTHFAVAKTVENSPEKEVFISDLKIQNEKKLDVSKSSVKTDDRPM
                     SKDKETMTEKTVLIPQQPVKEERKQSVVKTDTEEEQYSENECVENVIENIYDNVFIVS
                     SQEPLDFSRPIYSRSLTSDKALVILKDSAQLVPAKDLSSSGHRDIAAKEKASKETETK
                     IRRDRSETKRSKEMKSKSSMTDHPKPSESKSKIVPAKFLEDVIAELVNKLVFTFISDK
                     TTDTNEQKPGELYDTAMRLVNSMTKELSDAEIKVFRPEKEDEVQAAKEPAPTSPPEVK
                     ETVTKEPSPSTNIKNEDQMSDVQKTPEQSSPDKLPALEKIPSIEKSIVNKIVHSCVCN
                     IFKECKSQESICENINSNGENLAKRLTSTVINEIFQHQLNLIFSDEVPASACVPLESK
                     DVEQKVQNVVQTVSKECQTASPYTVQLPYKFLEDVTSGLLAKVFSKLSNVKTKLTPEN
                     VLTQLDFLQSNLVKTIAAEISKNEDLIIQYVESLHPNDDEVIQLVVQTIYNNLLPQFG
                     SQEILQKCIISGCKLLSKTIVDLVLREVTGNQLQNYFGGELTPIQCAEVDNVVENILT
                     NVVLTTPSQPSGPRKLSYNIIETIAVKFLSKLLSVFPKGHPERTKSQETEMRKITSKI
                     LHSIQEFISKSKIKVVQPVKESEAVPSADKAAIEKVVNSVYTNLLKHCGSPTSAFEDL
                     MRKSDVISDIIGFSMVKEISNSEFQPQAEEELSSSELALEAVKIMEKVVKIIDELKSQ
                     EKPASITDVMLDSRVLEEALALFLAKLVKTPGPASKDTTSLTKPELNKIASQLTKSVT
                     AEISKSNISLVESNHEEQSLDPENIEVISQVVESVYSNVVKQSGTENELSDIKGTKKA
                     FPKKVASLIVDGVSSVPSCRVITESSYTAAHGDLDTNRIIEKAQKHAALMSSDSDKDS
                     KKELEDEFPVRIVPHVRNKPLRIDPNIVSDHLAVISMKTQPLETLQMDCLKRTGCSIA
                     ELRRNSIRGIGPSSTDVSEMGTRQKERRISLDRTGRLDVKPLEAVGRNSFQNVRRPDI
                     TRVELLKDINNKTDLIIRLVAHDIGRKESDSSLSEGMVSDEEEVVLGEVVGDQCLRKI
                     SGGRVQQVKKSAESHVVSSKTATSTSNLKRFLALSKCCQPTSGENIESIEESGIQIMD
                     PNKAYVKRAAAELDMPSCKSLAEETTSRDKLQYKEEEILASEPTHYFIHRIMSTSSYN
                     QEDLISGEAEEFLPDAKANALEESCQEPQEGNSNSLEFVTIYKGSKHIAGSARLSKEH
                     VSEMPRSSISKQGSRVLAKVSSTLSKVFSRSSGSIPKSSSPPHQDKR"
     exon            168..293
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            294..455
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            456..545
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            546..685
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            686..827
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            828..938
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1062
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1149
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1265
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1302
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1406
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1470
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1528
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1562
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..10506
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            10507..20165
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            20166..20660
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            20661..20752
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            20753..20799
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            20800..20843
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            20844..20913
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     exon            20914..21110
                     /gene="Fsip2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      21087..21092
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fsip2"
                     /note="hexamer: AATAAA"
     polyA_site      21110
                     /gene="Fsip2"
                     /note="major polyA site"
ORIGIN      
        1 attcggacct gagggaccac ggcgaaggaa gccaggaagc atcaagggag gatttgagcc
       61 caggcggcat ggagctgtac ctcagtgcct gctccaagac tgccaatgtg gccgccaaca
      121 aggcagcctc cagcaccgtg gctgaggaca gtcagcaatg tgtggatggc agacacaaaa
      181 ccccaattcc aggggtagga gctgctcagc tcctagatct tcctcttggg gtcaagctgc
      241 ccatgatccc aggaaccgat actgtatatt ttactacgaa tatcagtgaa aagctttttc
      301 gaccttccta tggttttaac ctgagtgatc cttactgtcg acttttggaa acccaatata
      361 aaagtctcca tgatccacat ttaagaacat actataagcg caaagatatt ctgaggaggc
      421 taaagaaagg tggctatatc accagcaata ataaaattgt atgtagcttg agggagctga
      481 ataaataccg gcagtacctt acaagtctaa agttagactt tgaaagaaac tatttaagag
      541 aacagcaatt gatatcaaaa cagctacata aactgcaaga aaccagccaa cttcctcact
      601 gttctgatgt cacacgattc caaaactggt tgttacagga caacactcat tctattaagg
      661 accaagaacg tttgttaagg cacagatatt tggatatgat aagtaaagaa ttggaacaac
      721 ttgagcgcac agcagaggaa caacgcttac tccgcattga cagagacgaa agacgacagc
      781 gggaatacac aagaaaaaaa cttactcttc gtagaaaaat tgaagaggaa tggaagacaa
      841 aggagatgat gcttcttaca aagattggag aagatgttaa gagagaacag aagatagaag
      901 agcaaaggag gaaaagccga gaagagagtg acagaaagaa acaagcaatg ctagagaaaa
      961 aaatggctta tcatttacaa aagatgcagg acactggctt aaaagatgac ataggaagaa
     1021 atggatttga ctatagagga cagaatggaa ctacgtttga atcttcctca aagaagagaa
     1081 agaagcagtt tgatgatata aaaatagttt atcctgatgg tgaccagaaa gcatatagag
     1141 gaacatcagg acaagtatca gccacagtta atcagtctca gagtagttca aaggatgtta
     1201 caaaagtgtc ggcatcctca gttacttatc cagcagaagt acagaacagc agttcagaac
     1261 aaaagagaag tgaagtaacg aaaagattaa gtgatgaaag agatcctgga actacatcag
     1321 ctagagagtc aattatttca acacaactat cacccacaag gaatgctaaa ctttcacaga
     1381 tatctttgga ccatcaaaaa gaagagaagg agatgaaaag tacttggaat ggaggactaa
     1441 gcaagaagtc aagctatgct ggtgaaccag gatcaccgac agatgctcca ccccagggta
     1501 tcttttcttt tcctgtaaac tcaaatacgc aacaaaatct acaacattgc ttgaaagata
     1561 aagtaacttc tgaggaatta aatagcataa tccaaaacat aatgacctgg gttgtagcta
     1621 cagtaacgag tatattatat ccagccatca caaaatatga agaaagagta cagaataata
     1681 catacccagt gactgatgac tctgatcttt cttcagatag ttcaagcttc tgtagtacat
     1741 gcagtgaagg ctttacatac agaaactaca cagctaaaac acttccagta gatccatgta
     1801 catttgccag tgacatgcca ataaagaaac cacctacacc tttgaaacct ccttctgcac
     1861 acgtggaaag aacagttatt gaccaaacat atcaaaggca aggacagtct gtgccttcac
     1921 aagtcaatta ccaaaaaacc agcttggact atcaatttcc taagatagga agtagtaaat
     1981 cagatagtca cctcttaaca tcattagaaa catgcactaa aaaatcaaaa gatgctacca
     2041 cagaaacaga gagtttagag atttcattgc tatatgataa aaaagcaaag gccatggatc
     2101 agattaaaaa tttaaagaat gtctttgtaa actttaagtg tcacttgaaa ggagaaacac
     2161 aacttatttt agagagtatt tttcaagaaa taatgtctga cttaagccag gccattcctt
     2221 ctctttcttc tgtgactgct gaagtttttg ttgatcagac tgaaacggaa agagaagagt
     2281 tgctctccaa tgttgacata tgttcagtcg cttcggagat tgtagaaaac atgcttgaga
     2341 agctggagtc tgctgttgag aaaagatgtg tgcagatgtt ttcacaagaa gacttgtcag
     2401 ttgatattaa accaagttta tcaactagtg gtgactatct ttcatccgta gaaacaaaac
     2461 cttcagaaga gacactgagt tatactttgg agccaatgtg tgatgttgca gatgatatgg
     2521 tacatgccat tttagaaaaa ttgatgattc ttgcatctta taagaaaaat gatgttcctc
     2581 cagaagacac aactaaacat tttcaacaaa ctaagacaga gccaatacat aaagtccatc
     2641 aacaaactga gcaaaagaaa gctagctttg catctgatcc tgctaatcaa attgtgaaag
     2701 aagagataca aagcttaata tcaagtattt tttcacagtc ctctctggtg ggttatgtag
     2761 aagaagcaat cagcactata ctaggctatg tccaaactga actcaataat gagagactta
     2821 ttgcatctga agaaacagta gtccttcttc agctgctgga tgatgtctta actcagcttc
     2881 accagcagcc agtaaaagca ggtgttaaaa aacctagacg acctagagta aggaatcttt
     2941 ctgaccctga agaaaagtat agagtcactg gcactagacc atttaacaat cttaagtcta
     3001 aaagaccatt tccacccgtt aatgttcctg gaatggtcct ttattctgaa gatgatgatg
     3061 aggaaatcga taactttgtg caaagtgtgc ttgattcatc tttcaatgat gagaaatcaa
     3121 gttcacaaga gcaggttccc aactattggc ctaaaaagag agatacttat tttgaatcca
     3181 aaagaagtaa taaactgcca acaaaatcta cttttcaaaa caaagttgga tctcatgact
     3241 ggggattaaa gttggagttg tctcttagta gtgaagacat tgtgaagaca aagcattgct
     3301 taggccagga accttccatt ttcagccaag atcaaaagca ccaaatacaa aaggcttcag
     3361 aaaacatagt taaacatatt ttaacagata tgcttaagga tatgtcttct gattcatcta
     3421 gtcacttagg aagccaaact ggcaaaggag cttctgcttt catctctgaa aaatctcaag
     3481 gactatcaga tcaagaatgg atggaacaga tgttctctgt gtcagaaatt tgtgcatttg
     3541 cacatgaaat aacagattct gtgataaata tacttcataa ggcttcaatg cacattccta
     3601 ataccattaa aaatgccttt acatcagttc atcccactca tgtagctcct tttgatactg
     3661 cccacacatc caaagaaaca ccaagtaaaa tgccatttaa agtatggttt gacagtgaaa
     3721 agaaaatgaa atatttatct tctctcaaca tggagcatga aaagacttcc cagttaagat
     3781 ctggaaaatg tgaaccaaag cgtgtaaatg atattactga taagatcact aatacaattt
     3841 ttaaaaggct gaagttattt gtttgtccaa aattgcagat aggcaacaaa tcttcactga
     3901 tagaaaaatc attacattct caacttagta cttacacaat gaaaatagtc aacatcattt
     3961 tgcatgctat acaaagtgag ctagaaatca acaaaacaaa accaaatctt aaggagacag
     4021 accaccccaa gtgccataaa aacaaagggt ggttcactga tcccaataaa gttgtagagt
     4081 cccgtgtcac cagtgtcaat gatgacatta tggaaagtcc gttattgaca tgcatatgtg
     4141 aaatgatatc aagtacaaat gaagataaaa aaaatacttc aacctataca gataaaacat
     4201 tatctacatc tatatgtgag tctggcaatt ttcataaaca aagtattttg tcaaataaac
     4261 aggataaaaa ttctttttgc cagttgttgg ctaaaccttg ccttcagcac agcttggctg
     4321 atgaaaagga tttcaaggtc agttccaaat tggaggtgtt agatcaaatt ggggatacac
     4381 tgcatgagat gttaggcaag ctcacaggtg atcatcctga tcctcagcca tcttgcagtc
     4441 atcaaaacac agaaaccata gataaggatc ctccaacaat gtctaacact cagctcattt
     4501 ccaaagcaat tctggaaaac gtccttgcaa aattatgtga tgttgacatt gatactagca
     4561 ttgtaaattc tggaccaaaa actgttcccg agtcacttga catagacaac ctatcatttg
     4621 cttcaaccat ggaggaaatg gccaaatgca cgaacataat ctctaacata atttccaaaa
     4681 ttatgaagga taataaggag gtgaccaaaa gcaaagcaaa aaatgatctt ccaacatctt
     4741 ccaaaacaga gatcccaaaa gaaatgtgcc cccaaaatct gaaaaatatt gcttcagata
     4801 ttctcaacat ggtttttgct aaactggaac attttgcaag tggaagtgta gtaaatgttg
     4861 gtaatcttaa tgatgaaaat aaaaaagagc atacagtgga ctgggaatgt gaaagcaaca
     4921 gttctcctgc agattctcat gataaatcat tgcaatccac tttatatagt catgcaaaga
     4981 aggtatcaaa tggtattttg aaagccattc aaacagaatt aaatatgaac ccacccgatt
     5041 gtaagacaga taaaaagaga tcaccagagg agacacaaat tcttacaaac atcgttgatt
     5101 taattttaga tgtagtatct tcagatatgt ttgctgaacc tgaatctgag aaccaaagca
     5161 atgaaaatta tggataccga ccaacttatg gaaattttct tcctggagga gcagaatcag
     5221 attcatttct agatgatgac acacaaaata aagaacttat cagagatgcc acatcattca
     5281 atgaggaaac tagaaccctt tctactgacc agatgggtct agagagaacc ttaagcaaaa
     5341 ttgaagtgaa actcaaagaa ccacatagat ctccaattgt tcccattata agaaatattt
     5401 tgaatgaaat ttttcaaagt gctctaatca atcaattaaa tgtgttttca ctctcacgtg
     5461 cccattttag tggaatgcca caaaatgctc ctacatcctc tactcaaaca tctgctcact
     5521 ttatggatca aatgatgggc cccttagtat ctgacacaga tgtaagtata gtggtaaatg
     5581 atgttgttag gacggtattt cataagcttt attcagctgc catgactgaa agacatgtaa
     5641 gtgaaaacag aggcaaaacc atcatccttt cagccaatgt ttctttccgt gagtgtacct
     5701 atggaggaaa tgcccctgtc agtgggttaa atgaaaatgt atgtgatctt cagtccagct
     5761 ggaatgttga caagcagatc aaaataaatg tagttgaaga tattgtgcag gcaatattag
     5821 gaaatttaga aacttttgct gcttccaaag tagaatctct tttctgtccc caagtcaaat
     5881 tcacagttcc agtgactttg ccagtaatgc aagaagaggg gtcattaagc caagcattgt
     5941 caggcaaaga ttcatattct gataatcaac ttccctgttt agtggatcat ggcaatccag
     6001 aacagatgga ctcctggtat caaatgtctt tgtccaaatt aaatatttat gcaaaagatg
     6061 tggctaggaa aattttacaa ggcatcaaac atgagttaga taaagaacaa gaaagccctc
     6121 tcttgacaaa taacattgta gtttctgaga atattgcaag tcaagttgtt aacaaggttc
     6181 ttgatattgt gtcatgcaaa agtaagtgtg ataagaaaag ttctgacaaa gatcattact
     6241 cagagcagca agttggtatt attgaacaac tagtcaataa aagagaatat cgaaaaatac
     6301 ttgagtttca aattcaagat accattgaag gaatcttatg tgatatttat gaaaacattt
     6361 tgtatcagaa taatctctca tttgccacac ctaccctgaa atatggtata cctgcaaaac
     6421 actcagaagc aaattttgaa caagtagtta tgggtacaaa tattatccct aaagtctcag
     6481 ttcctaaagc agatgtcatt ttggtgtcca aagatatagt ggatattgtg cttcataacc
     6541 ttacaagttt ggttgtgctt gccataaatg caaaggactc tgcccctgca agagtggcca
     6601 tctatgacat ttttccaaaa ccacagttcc aacagcctct ttctataaca caaagaactg
     6661 aagaaacacc agggcatttt tcacattcaa aaaataagaa tttgggttct cctgatgttt
     6721 atcaggtacc tgtaaatggc aaagaagaca ccaaggaact tgctcctgac ccatgcaagg
     6781 aaaacgcaaa ccgcattact caacctattt tcaatcggtt acagtctttt gccacagaga
     6841 gaataaactc actaatgact cctgcatttc agtctaaagg aaatgtattt gttagcccac
     6901 aatttgaaat tggtaaagat gacaactgca tttttcatga accaggccaa gctgaatctg
     6961 atgtggatgt tctaaaatta acaactagaa cagttactag ccaagagctt gtagaaccca
     7021 tttttaccag ctgcagagaa aattttggaa ctacacccca tttatcacaa actaacctta
     7081 aggactatgc tgccttcatt gccagtacta ttctgaagct tatcaaaaat gatttagact
     7141 tagaagtaca aagtatgcac acatattcaa gccacatttt atttcaaaag aatatgattg
     7201 tgagtgaaat tgttaataat atcttaaaga ttttacccaa taaagaacct ataaaggaat
     7261 tctttttatc ctcaccagag aactctagtt gttcacagtt aaccatatca agtgaagatt
     7321 tggtgggata caaagagaag gaaaaagcta ccgcattgcc acagtttaca aatgactcct
     7381 tagaagaaaa ccaagtaaca gtagaaaaag aaagccagag agatgttttg gaagaaatat
     7441 ttatgagaaa gggagaatca aaaccaagag aaaaaaccga aatactcagg acagtggaag
     7501 aggttttgaa gaagctgagt caaaagataa tggaaatcat aggccacgtc gctccattta
     7561 atgaaagccc tcacacagtg tctaagtcta aaagtaaaac agcagctgca acacagaaga
     7621 aattctttca gtcacgaatt aacaatgtat caaatgatat acttgaaaat gttttgagtg
     7681 agatgcactc tgtggttgta acatccttgt acagaaataa taaaagcaag agagagggag
     7741 aaatgcatga cagcagcgat agctcctcag taaaaccgtc aggctctaga gaaactaagc
     7801 caacaagaaa aagaagtagt cccctgagac tgggggtacc acagatgcat cctcatgctg
     7861 acaatttaaa tgctcttgtg ttagaaaaca ccattttgcc atattcacca ttgcaaattg
     7921 gaaaatattt agttcaaatt gttctagaaa atttatcaaa ttttgtctcc ctgcatctag
     7981 aagagggcta tccacctgaa gggagctatg atgacctgta tcttcttaga cttcataatg
     8041 ctaaactcag cccaaagaac agcccaaggc caggaggtaa agcaagttta aaaatgagat
     8101 caaaaatcaa ctctctctct aaatttaaaa caaaaccaca ccttggtatt agcagtacta
     8161 agaccaaaat caagaacaag ttatctgctg gagagaaaac tccaagagag agcagatcca
     8221 aaaccgccct tgggctgcca caaactccac aagtggaaga taccaaaacc acactgaaaa
     8281 caaaattacc agttgcagaa ttaagactat atgccacaaa tataataact gacattttgc
     8341 aagtaattct gagcagtctt gagagagcgg cacaacacag agccatgttt aacacgaaag
     8401 tcttagcatc tagtcaaatc cttgaagcaa gtaaaattgt taatgcagtg ttacaagagt
     8461 tatatgctac aaacaacgac aatttggctt ctccaatcaa catctcaagt ctgagtgatc
     8521 gtcgcttatc caagcagaat ctgggtgcag gttatcctac ggagcaacca tgtttttatt
     8581 tagaaaatgt ttcctcacag ttagaacaga tatttcctaa agaaggtata ttgaaaaaaa
     8641 tgtttgacaa atggcaaaca gaaacaagtg atacagaaac tgaaaagtct aaacttttaa
     8701 ccatagccga aaacatttta actgaaattt caataaaagc caaagattta gagtattcac
     8761 tttcactttt aaatttgcca cctcttgaag agtgtgaaaa cagactctat gaccgcttta
     8821 aaggtgtctc tactagagcc gaggacacaa atgcgcaaat caatatgttt ggacgggaaa
     8881 ttgttgaaat gctctttgaa aaattacagc tgtgcttctt gtctcagatg cctactcagg
     8941 atagtaatgg aattctaaca agtaggaaag aacacggtac cagcaagagt aagcatgggg
     9001 ttcccaccaa gcccatcctc ggtggcatac agacttataa ctcaaagatg gcagaccaag
     9061 tatctatgag ccctagcaac caaattgtgc atgagattgt agaaagagtc ttacacatgt
     9121 tagagtcatt tgtggacttg aagtttaagc atatctctaa atatgagttt tctgaaatag
     9181 tgaaaatgcc aatagacaat ctctttcaag cccaacaaag acaattaagc aaaaagatgc
     9241 tgccaaagtt accatttaga aagtttggtg atgagtccaa gccaggcact attatatcca
     9301 aagacgatgg acagaataca ctcttacagg ttcacttatt ccattcagaa ttgcttacat
     9361 attctgtcac tgctgtcagt ggcatgctta ggataatcaa gaataagcta gacaaagaaa
     9421 taagccaaat ggaaccatct ccagttagca tactgaaaga aaatatcact gcaagtgaga
     9481 tcattggtac actgatagac cagtgctccc attttgaaga gtctttgatc aaaaaccttc
     9541 ccaccaaaca ttggttccaa ggaactgaga atgtttacat tgttaatcag gttgaatttg
     9601 caactcctgt gaaaatgcct ccatcaaaca cgagcgacac tcctaggacg aggaggagtt
     9661 cacaagggag tgtgtcaggc atggggttta gttccgagga tgatatgaaa gaaaagtata
     9721 gcgtcacatc taattcatct tcacacatca gttcctgtgt agaaaacaca aataaaagtt
     9781 tagagccaat gggaaggtcc aactcagaag ctatgccatc tggttctaga cacaaagcac
     9841 acgaccacgg ccagaggaaa ccaaacttta caccatttga gcaagtcaca aaaactcaca
     9901 actttcttcc tcaagggagt gtgttacaaa aattgtttaa aaaagtaaac gattccacag
     9961 aagagtcact aaaacaagtt ttgtcattta tagaaacggg gaaacgtgaa aatccaaggg
    10021 tttttcatta tgagaccacc aaatcagctg agccaaatga aattaagaca actgctcccc
    10081 ctctcaaaat atgtttagct gcagaaaata ttgtaaacac agtactatca agttatgggt
    10141 ttccccatca accaaacact aacgaaagca cggagaccat gaaaccattt tttatgtcaa
    10201 ggcaaattcc tttgtctgaa gtatgtgaag gacaaaaaga tacagagaaa actttgctca
    10261 aaacgtggta tagccgaaag gccctcattc aggaggagga aagtgaaggt ctcgaagcct
    10321 gccaagagga tttttcttta ttacacaaat ggaaaaataa gaaaccccaa atgacaacag
    10381 agactgtgga ggaaaccaag accattgttt tcgctgatca tgaacttggt ccaaatgaaa
    10441 tgcatttggt tgcaagacat gttacgacat ctgtgatcac acatttgaag aacttcaaaa
    10501 ctggagtttc tactgagaag ttttctcatg tatcttcact ctcaaaaaaa attgatgatg
    10561 caaatcagcc tctaataagc atttacagca attcttcagt ttgtcagttt tgtgagcatc
    10621 tctcagacgc agttatctgc tacctatttt taaacatttc tgatggcatc aaaaaatgca
    10681 gcagagagaa agcatgggaa atccaagatg caataattga caaaaatgtc ataattcatt
    10741 ctcaattgta taaaaccagg tctatttcta ttggagatct cgctttaagt atttttgaag
    10801 ttattgttga agttcttgct aatagaaaca tgataaatgc tgataaggca catcaggctt
    10861 ccataaaagc aaagtacatg ttctgtccag gagtgacttc ttctgatttt gatgatatct
    10921 ttcaagatct cttaaaagaa gtgatctttg tattgtccaa aatattagga ataaatcatt
    10981 ttgaaaataa tgtaagaaac aagtcatatc ccacacttaa aaataatttg cccgtgttca
    11041 acaaagtcaa taccatagaa aatcagatag gccccaggaa gttggaatca tctcctcccc
    11101 taactgatca acttgctcaa aaaaataaat taaattacct ggcacgtagg ttaaacagtc
    11161 tggttggcag cctaagatct cgcgaatcca aagaagttgt caatgaagtc tttaatattg
    11221 ttttagattt atttttacca gatgagatcc ctgatgggga tttgagttct ggtaaactag
    11281 caaaaacatt ttcctcctca aataatcaac caagtaatag aagccttgca aacaatgtag
    11341 ggctttcccc taaatcaatt tttcttctca atattgtgtg tgagaaactt attcgaacac
    11401 ttctagaaaa gtgcatgggg ggcaccccat tttttgagga tagttcactt tttcgtgaaa
    11461 taccagaaga atgtcaacat gtcaaagttc ttccaagtgt tcaaggtgga ggttttgatt
    11521 atcgtgaggc accaatggac tgtgaacaat ttcaaggaga ttatatgtca gagctgttgg
    11581 aaaatctggc agacgttgat caagatttat tatcatcaga ctgtatactt aatgtgattt
    11641 cccatagctt ggttaaatct ctgatggaca aactatctca tggtttacag caagctccct
    11701 ttgaaaacaa atacaggaac tatagaacaa gagaaatgca acctttcatt acaaaagcaa
    11761 aaaggcaaga attaatagaa ccagaagaga ctaaaggcca tgtaggattc atgagctatg
    11821 acaataactt cttgaccaag tccttaaata ataccaatgc aaatagcttt aaaaagcaca
    11881 cacagtttgg caaaaaacat gcaggaaaat ctatctcttt gtcattttct gatggaaaag
    11941 aatcaagggg aatcaacaca gcatgctttc ataagctatg tcaaagaggt gtaaatggtg
    12001 gtgttttttc agccacgttt ttagaggaga taatctcaga attattttat aatctgtcta
    12061 catcattgtg gaagaaaaat ccaaatatca ctgaagcctg gctaaatgag ataaatacat
    12121 tacttatcaa caatgtagtg aaaaagttaa atgatgctga aattactgtc ctaaggtatc
    12181 ctgaagaaag attatatttt ccatcagccc ataaaggatg tattgctaag attgttgatt
    12241 ccatttatta tgatgtttta cagcaatatg aatttacagt aacctgtggt ggtaatctac
    12301 cctatgacaa tactccagta gctaaacgaa tatctaacag catattatta gaggttatag
    12361 actatcagct tccatcttgc ttcaagggaa agctcagatc caatctatat cacactctca
    12421 atgctgaaat catactgtat aaacttcaca atagtctaaa aaattttaac tctgaaccca
    12481 tgacttcaaa agattatagt accatgttac cacactcatt tttagaatat gttatcagaa
    12541 gagtcttagc tcaacttatt tccttgccta ttaagtcttc atctttagaa aaaaagtatt
    12601 tggcaagttc agattttaat gaaatgtcca actgtataac aaataaggtt atgtcagcca
    12661 tttcaaaaca taaaatctgg ttgaccatct atgataatca atgtctgtat acagataaaa
    12721 atctccaaaa aatggtagat tctgtttaca gtaatatttt gcaaatgtct tcttctgttg
    12781 attcaataca gaaaaatata attagtcgaa gtccaattat gattgaccaa atagccagtt
    12841 tcattatcca agagattatt gaaaaccatc ttcagccatt tttgtgtgga gagagattac
    12901 ctcgccccaa aactccactg gatgaagtat cttacatggt caaacaagtt ctcagtgacg
    12961 ttgtagagtc tcacaagtcc cagaagccat caccttttgg catttaccct gataagttag
    13021 taggagaaac cgtcaccaga gtcttatcaa agatttttag tcctaatact aatattaatg
    13081 ttgagctgga aaatgtgacc caaaaaatag taagctcagt gcataagcat ttagacaaag
    13141 ctaagattcc gattctatgt cataagcaac caccctttcc ctttagtaat acagacattg
    13201 tagatgaact tgtgacctca gtatataaga atgttttgaa gcagcatgga ctagatcctg
    13261 acattgatga gtcagtaaat ggtgaagttt ttgtggaaaa tattaccaaa ttaatcacag
    13321 ctgctatttc agactacctt cttcacccac tgttttctgg tgatttgcca gctgcctctt
    13381 gttctaattc agtgactgat catactgttt atgacattct tggtgacatc aataaatcta
    13441 gtaagccaaa ccagacttta cctctgtata atacattact accatataca tttttagaag
    13501 atatgatcag agtactatta tctaaatttt ttccttctgc ccctaaaatt gattcataca
    13561 aagcagcttc aaaagataaa gaaggagtca attttaatga aattgcttcc aacctgatca
    13621 gtgatattag gagaaaaatt tcccaacatg aaattagatt ttcaaaagat gaagataaaa
    13681 ccaagtcctt ttactcagaa aacgatgttc agcatcttgt tgatgcagtc ttcatgaata
    13741 ttttagaaaa ctatggttct ccagaatcag tggaacaaaa tatcacaaaa agtaatgatg
    13801 tcttcattga tcaaatagca ggttttatta ttaaatatat ctgtgaacac catcttcagc
    13861 catttttgga aagaaagcaa ttatctactt catcgtacaa atattctgat gatgacaggc
    13921 aggacttact ttatggtagt gcttattcct caacatttct ggaagatgtg gtctccggtg
    13981 tagtgagcaa aatatttcat agggtgattg gcattgtaca agtgaactca acaataaact
    14041 cagaaaatat cttgtttgat aaagctgaaa acctcatata ttggataaca gaggaatttt
    14101 caaaagctca ggttaccact atagagaatg ctgaagaacg gttgagttta tccccagtag
    14161 aaggaaatat actccaaaaa atcattgaca ctgtgtacag caaaatttta gaagaacatg
    14221 aaatggaaat catgcctaat aaagattttc taaatgatac aaaggcattg gcttcccaga
    14281 taactgaaat cattctgagt gaaatttctt atttccaaat tccaccagat ctcgtagcaa
    14341 atcttccttt acgcttacat tccaaactta gtcaaaatgt cttggtgaac aaagtgcatt
    14401 atgacattag taagtcaaga ttccgaagac aggcttcaac gatgtacact accatgctct
    14461 cccatgttca tttagagaag atagtcactc agcttatgtc tcagataaat ccatcagatt
    14521 ccagtgtagg acattctgac acttatcaat cagaattgag taacacagtc gtaaaactga
    14581 ttaatgaaat catgtcaata atttcaaaac atgcaatatg tattgtaaaa catggaaatg
    14641 aaaaacagag catgatttca gagaaggaaa tgcagtcgat ggtcgattcc atttatgctg
    14701 atctttccca ttcaaatctg taccagtctc ttacaaaaga taaaaagggc ctaagtagca
    14761 tacctgtttc aaaaattgca aattttataa taaaggagat cttcaatcat catctagaat
    14821 cattcttatc aggagataaa agtattcttt cagcttcagt ggctcaaacc tgcaagaaga
    14881 aagcaacaac aagcactaag caaagggagt tgtcattcat tgtgaactca gctgtctttt
    14941 tggaagaagt aatcactgag cttttatgca aaattcttca gacttttata cagaattcct
    15001 tgagtatgga aaccccagag agagcaatag cagaaataat ggacattgtt acaacattag
    15061 taaaatcaat tgtttttgag ttcacttcat ctgagatttt agttgcagaa catttggatg
    15121 aaagtctatg gttttcagag acatataaag aaatggttca aaaaacagtc aactcagttt
    15181 atggaaatat attttatgaa tataaatctc tgactcaact acacagggct gtacaatatg
    15241 acacctcagg ttttggaggg aaaatgtatc attttctatt ggaagaaatg tatgattatc
    15301 aggtgcagtc attagtttca ggagaattaa tgccttcttg ctatgcttca cctcaatctg
    15361 caaatatcat caaaaatgtc ctcaatgtca tcttgaagga taccaatgca ttaccatcat
    15421 gtattacagt gctcccttgt tctctgatag aaaatatgat ttacaagctt ttagaaaaca
    15481 tctttccttc agatgacact acaaatgaac taaagaagga ggagaaggag gaggctgggc
    15541 cagatgatgt tgatgagttc atggctgcag cttcaaaact gactgatgaa attatacaag
    15601 aaatttctga acatgagatc aggtttgcca atgcagagga tacagccagt atgatatatg
    15661 aaacaactga gaatttcatc gactctgtat gtaataatat tttgaagaac tctgaattcc
    15721 aagcagaagt acagaaagat gcacacaaaa agggaggttc atttctcagt aaaatagctg
    15781 gttcaattat taaagaaatc atggatcatt atttgcagtt atttttatat ggtgaaggct
    15841 cacattcaag taaattacct cattttggtg gtgcttctgt tgttgctaaa tctgggaaag
    15901 aaaaggcacc atcctctctc ttttcagctg catttttaga ggatgtaatt gttgaccttg
    15961 ctcacaaatt ttgttctttc ttaactctta ctgatgatgc caggaaaaaa gatttgccag
    16021 aggcagaaat tgtaagctta gctattaagt ttgcaaactc tctcatacga gattttagga
    16081 aaagtggaat caaagtatta ccacatgctg aagaaatatt ttctttccca ccaattgcaa
    16141 aggagacaat tgatgagata tctaattttg tctatgatca gttcataggg aaattaggag
    16201 ctgatggtat tcagaaggat ggcactggca acatggttat agaaatggtt tcttctttgg
    16261 cacaaaaggc aatctctaca ttcaagattc agccactatt ttcaggagac tggtgttcaa
    16321 ctttcttctc atttctagat gcagaaaata tctcccagag ggttcagctc ctcccaaagg
    16381 agacatcaat gcaaattagt ggcgccttaa aacagaacca gcttgctcta tctaaaatca
    16441 catcaattaa aaaagatgac acccaagatc caatacttaa ctctatagct accattatga
    16501 aaagtaatat catcaatctt ctatcaggac caagtgcagg cgtcacagat gcaaagaaag
    16561 aagatgaaag caaggtcaaa cctgccaccc gagagaccac ctcaccaccc acatctccac
    16621 ctgccaccat gaaaagccaa ggtagtcagg tacaacagtt agctacatct ccacccacca
    16681 gcatgaagag ccaacgtatt caggtgcaac agtcagtgat gtctccaccc accaccatga
    16741 aaggcaaagg tgctcaggtg caacagtttg ctacatctcc acccaccagc atgaaaagcc
    16801 aaggtagtca agtgcaacag tcagcgatgt ctccacccac caccatgaaa agcagaggtg
    16861 ctcaggtgca agagtcagtg acatctccat tcaccaccaa ggaaagcaga ggtgctcagg
    16921 tgcaacagtc agcaatgtct ccacccccca gcatgaaaga cagaggtgct caggtgcaag
    16981 agtcatcaac atctccaccc acaaccatga aaagcagggg tgctcaggtg caacatttga
    17041 gcagcaaata taaaggtaat gaaactggga aagagaactt agtcctagtc aatgagcagg
    17101 ggcagattct tgaaatcttc acccactttg cagttgctaa gactgtggaa aatagtcctg
    17161 agaaggaggt atttatatca gatttgaaaa tacaaaatga aaagaagctt gatgtcagta
    17221 aaagttcagt aaaaacagat gataggccca tgagtaagga taaagagacc atgacagaaa
    17281 aaactgtact cataccccaa cagccagtca aggaagagag gaaacagtct gtagtgaaaa
    17341 ctgatacaga ggaagaacaa tactcagaaa atgaatgtgt tgaaaatgtc attgaaaata
    17401 tttatgacaa tgttttcata gtatcttctc aagagccatt ggatttttcc agaccaatat
    17461 acagcagaag cctcacaagt gataaagcac tggttatcct taaagattct gcacagcttg
    17521 ttccagcaaa ggatttatcc tcatcaggtc acagagacat cgctgctaaa gagaaagcaa
    17581 gtaaagaaac agaaactaaa ataagaagag acagaagtga gaccaaaagg tcaaaagaga
    17641 tgaaaagtaa atctagtatg acagaccatc ctaagccatc agaaagtaaa tctaaaattg
    17701 ttcctgccaa gtttctagaa gacgtgatcg ctgaactggt gaacaaacta gtatttacat
    17761 ttatctctga taaaactaca gatacaaatg agcaaaagcc aggggaactt tatgacacag
    17821 ctatgagact tgtcaattca atgacaaagg agctttcaga tgcagaaatt aaggtattta
    17881 gaccagaaaa agaagatgaa gtacaagcag ccaaagaacc agctcctaca tcccctcctg
    17941 aggttaaaga aacagttaca aaagagccat cacccagcac aaatattaaa aatgaggatc
    18001 aaatgtcaga tgtgcagaaa acacccgaac agtcctctcc tgacaagttg cctgccttag
    18061 agaaaatacc atcaattgag aaatcaatag tcaataaaat tgttcactct tgtgtttgca
    18121 acattttcaa ggagtgtaaa tctcaagagt ctatttgtga gaacatcaac agtaatgggg
    18181 agaatttagc aaaaaggcta actagcacag tgataaatga aatttttcag catcagctta
    18241 acttgatatt ttctgatgag gtaccggctt cagcatgtgt gcctctagaa tcaaaagatg
    18301 ttgagcaaaa ggtccaaaat gtggtgcaaa cagtcagtaa agaatgtcag accgcatctc
    18361 cctataccgt acagttgcct tacaaatttt tagaggatgt gacttctggt cttctagcaa
    18421 aagtcttttc aaaactatcc aatgtcaaaa caaaactaac tccagaaaat gtgttgacac
    18481 aactcgactt ccttcaatca aatttagtaa aaacgattgc agcagagatt tccaaaaatg
    18541 aagatttgat tattcagtat gtagaatcct tgcatccaaa tgatgatgaa gtcattcaac
    18601 tggtggttca gacaatttat aataatcttt tgccacagtt tggatcacag gaaatcttac
    18661 aaaaatgtat aattagtgga tgcaaactcc tttcaaaaac catagttgac ttagttctac
    18721 gagaagtgac tggcaaccag ttgcagaact attttggtgg tgagttgact ccaattcagt
    18781 gtgcagaagt tgacaatgtt gttgaaaata tcctcaccaa tgttgtctta actactccat
    18841 cacagccatc aggtcctcgt aaactatctt ataacataat agaaacaatt gctgtgaagt
    18901 tcttatcaaa gcttttatct gtgtttccaa aaggccatcc agaaagaact aaatctcaag
    18961 aaactgaaat gcgaaaaata acctcaaaaa tattacattc aatacaagaa tttatctcca
    19021 aaagtaaaat caaagttgta caacctgtga aggaatcaga agctgtgcct tcagctgaca
    19081 aggcagctat tgaaaaagta gttaattctg tttatacaaa ccttttgaaa cactgtggct
    19141 cccctacatc tgcatttgaa gatttaatga ggaagagtga tgtcatttct gacataatag
    19201 gtttttcaat ggtaaaggag atttccaatt ctgaatttca acctcaagca gaggaagagc
    19261 tttcaagttc agagttagcc ctagaagcgg tcaagattat ggaaaaggtg gtgaaaatta
    19321 ttgatgaact taagtcgcag gaaaaacctg catccataac ggatgtaatg ttagactcca
    19381 gagttttaga ggaagctttg gccttgttct tggctaaact agtaaagaca cctggtcccg
    19441 ctagcaaaga cacaaccagt ttaacaaagc ctgagttaaa taaaatcgca tctcagttga
    19501 caaaatctgt aacagctgaa atttccaaaa gtaacattag tcttgtggaa tcaaatcatg
    19561 aagaacaatc tttagatcca gaaaatattg aagtgatttc tcaggttgtt gagtctgttt
    19621 acagtaacgt agtaaaacaa tctggaacag agaatgaact ctctgatata aaaggtacaa
    19681 agaaggcttt ccctaagaag gtagctagct taattgttga tggagtttcc agtgttccat
    19741 catgtagagt tatcacagag agctcttaca ctgctgcaca tggagattta gacacaaaca
    19801 gaatcattga aaaggcacaa aaacatgctg cactaatgag ctctgactca gacaaagact
    19861 ccaaaaagga attagaagat gaatttccag ttagaatagt tccacatgtc aggaataaac
    19921 cattaagaat agatccaaat atcgtctcag accacttagc agttatttct atgaaaactc
    19981 agcctctgga gacacttcag atggactgtt taaagagaac tggatgtagc atagcagagc
    20041 tgagaagaaa ttccatacgt ggcataggtc cctcttccac agatgtgtct gaaatgggaa
    20101 caagacaaaa agagagacgc atctcactgg ataggactgg acgactagat gtgaaaccct
    20161 tagaggctgt tggcagaaat tcatttcaaa acgtaagaag gcctgatatc accagagtag
    20221 agcttttgaa agatattaat aacaaaacag atctgatcat ccggcttgta gctcatgata
    20281 ttggtcgaaa agagtcagat agtagcttaa gtgagggcat ggtttctgat gaggaggagg
    20341 ttgtcctagg agaagttgtt ggagaccagt gcttaagaaa aatatctgga ggacgtgttc
    20401 aacaagtaaa aaaatctgca gaaagccacg ttgtttcttc caagacagca acaagcacaa
    20461 gcaacctgaa aaggttctta gccctgagca aatgttgtca gcccacatct ggcgaaaata
    20521 ttgaaagtat tgaagaaagt ggaattcaga taatggaccc taacaaggca tacgtgaaaa
    20581 gagctgctgc cgagcttgac atgccttctt gcaaaagctt ggcagaagaa acaacttcta
    20641 gggacaagtt acaatataag gaagaagaaa tccttgctag tgaaccaaca cattacttca
    20701 tacacagaat tatgagtaca tcatcataca accaagaaga cctcatttct ggcgaagcag
    20761 aagaatttct accagatgca aaggctaatg cattagaaga aagttgtcag gaaccacaag
    20821 aaggaaactc aaacagtctt gagtttgtca ctatctataa aggatcaaaa catatagccg
    20881 gtagtgcacg tctttcaaag gaacatgttt cagaaatgcc caggagcagt atttccaagc
    20941 aagggtctag agtgctggca aaggtatctt caactctatc aaaggtgttc tcccgatcga
    21001 gcggcagtat tcctaagtcg tcctcaccac ctcaccagga taagcgatga agcttttcca
    21061 cttgataaaa ttgtgattct ctataaaata aaatgatatt taaagtagaa
//
