LOCUS       NM_001195284            7491 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus fibronectin type III and SPRY domain containing 1-like
            (Fsd1l), transcript variant 1, mRNA.
ACCESSION   NM_001195284
VERSION     NM_001195284.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7491)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL807745.7, CJ115006.1, BB662298.1, BB626514.1 and CJ261972.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1). This variant lacks
            full-length support in mouse; it is predicted based on partial
            mouse and full-length human transcript alignments from
            GeneID:83856.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14995044.497807.1,
                                           SRR9219380.63841.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                AL807745.7         93969-94014
            47-166              CJ115006.1         47-166
            167-585             BB662298.1         205-623
            586-617             AL807745.7         122101-122132
            618-827             AL807745.7         142292-142501
            828-874             AL807745.7         144598-144644
            875-1416            BB626514.1         2-543
            1417-1417           AL807745.7         159395-159395
            1418-1536           BB626514.1         545-663
            1537-7437           AL807745.7         163577-169477
            7438-7491           CJ261972.1         416-469
FEATURES             Location/Qualifiers
     source          1..7491
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 28.72 cM"
     gene            1..7491
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /note="fibronectin type III and SPRY domain containing
                     1-like"
                     /db_xref="GeneID:319636"
                     /db_xref="MGI:MGI:2442443"
     exon            1..142
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1621
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cystatin and DUF19 domain containing 1; FSD1-like protein;
                     FSD1 N-terminal-like protein; coiled-coil
                     domain-containing protein 10"
                     /codon_start=1
                     /product="FSD1-like protein isoform 1"
                     /protein_id="NP_001182213.1"
                     /db_xref="CCDS:CCDS57276.1"
                     /db_xref="GeneID:319636"
                     /db_xref="MGI:MGI:2442443"
                     /translation="MDSQKEALQRIISTLANKSDEIQNFIDTLNHTLKGVQENSSNIL
                     SELDEEFDSLYSILDDVKESMISTIKQEQVRKSQELQSQLSQCNNALENSEELLEFAT
                     RSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLK
                     FLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFIMEYRKTNFDGLPRVKDERC
                     WEVIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGDYSDPVTLETRALNFSLDNSS
                     SHLNLKVEDSCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDR
                     FTGESYTVLGDTAIENGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCVHV
                     NSWLQNTFAAKHNNKVKALDVPVPEKIGVFCDFDGGQLSFYDAHSKQLLYSFKTKFTQ
                     PVVPGFMVWCGGLSLSTGMQVPSAVRTLQKSENGMTGSTSSLNNVTQ"
     exon            143..238
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            239..370
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            371..472
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            473..495
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            496..617
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            618..827
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            828..926
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1056
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1157
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1409
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            1410..1498
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..7467
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7446..7451
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /note="hexamer: ATTAAA"
     polyA_site      7466
                     /gene="Fsd1l"
                     /gene_synonym="A230072O16Rik; Ccdc10; Csdufd1; Fsd1nl"
                     /note="major polyA site"
ORIGIN      
        1 ggacgggcgg gatctctgcg ggacgggaca aggctgacgg cggcagaggt agcgggtctc
       61 taaggctcct ccagcttctc actcagctcc ggtgacaagt tcggcccgga gggcttagtc
      121 cctagccatg gactcgcaga aagaagctct acaaagaatc atttcaactc tggcaaataa
      181 gagtgatgag attcagaact tcattgatac actaaatcac acactgaaag gagttcagga
      241 aaattcttcc aacatccttt cagagttgga tgaagaattt gatagcttgt actctatatt
      301 ggatgatgta aaggaaagca tgattagcac catcaagcag gagcaagtgc gcaagtccca
      361 ggagttacag agtcagctca gtcaatgtaa caatgccctg gagaactctg aggaactact
      421 agaatttgca acaaggtcat tagatattaa agaaccggaa gaattttcaa aggctgccag
      481 acagatcaag gatagagtca caatggcttc agcctttcgt ctttctttga aaccaaaagt
      541 cagtgacaac atgacccatt taatggtgga cttctctcag gaaaggcaga tgctgcaaac
      601 tttgaagttt ttgccagtcc caaaagctcc agagattgac ccagtagagt gtttggtagc
      661 tgacaactct gtaactgtag cttggagaat gcctgaagaa gataataaaa tcgaccattt
      721 cataatggaa tacaggaaaa cgaactttga tggactccca cgtgttaagg atgagcgatg
      781 ttgggaggtg attgataata tcaagggcac tgaatataca ttatcaggct taaaatttga
      841 ttcaaagtat atgaatttcc gagtgagagc atgcaacaaa gctgtggctg gagactactc
      901 tgacccagtg accctagaga ccagagcact taacttcagt ctagataact catcatccca
      961 tttgaatttg aaagttgaag attcctgtgt agaatgggac cccactggag gaaaaggcca
     1021 agaaagtaaa atcaaaggga aggagaacaa gggcagaagt ggtactccat ccccaaaacg
     1081 gacgtctgta ggctccaggc caccagcagt aagaggcagc agagaccgtt ttactgggga
     1141 gtcatacaca gtgctaggag acactgctat tgaaaatgga caacattatt gggaagtaaa
     1201 ggcccagaag gattgtaaat cctatagtgt gggtgtagca tataaaactt taggaaaatt
     1261 tgatcagtta ggaaagacaa atactagttg gtgcgttcac gtcaacagct ggttacagaa
     1321 cacatttgca gccaagcata ataataaggt gaaagctttg gatgttcctg ttcctgagaa
     1381 aataggtgtg ttttgtgact ttgatggggg tcagctttca ttttatgatg cacactcaaa
     1441 gcagttgctg tattccttca agacaaaatt tactcagcca gtagtacctg gtttcatggt
     1501 gtggtgtggt ggactttctt tgagtactgg aatgcaggtt ccaagtgctg tgagaacact
     1561 tcagaaaagt gaaaacggaa tgactggttc aactagcagc ctgaacaatg tcactcagta
     1621 atggcaactc agactgtttc ccttcccttt gactgtgtgg cctttcccac acagttacta
     1681 acagatattt ctgagtggtg gaatcaggtt ttctatgttc tgctttaaag cctggagtct
     1741 gttagattaa ctaccaaata ggaagcagcc atggaggtta ttgcctgcgt cccagaatca
     1801 agcagttggg gtgcaggagg ctgacatagt gatattgagt agtgattagg aaaggggcgg
     1861 tgttgaactg tttgtgtaga aagccatctt tctgtctctt aagctcctct ggtttgtctg
     1921 gtaggtgtaa ttacgcctgg cgagccctgg gcccgggttg ctaagcatta aaagcttgcc
     1981 tttctccctg cccttgctct gtttctgctc ctcaccggct gtcattacat gctacactga
     2041 ggctttaaaa acacaaggtc ccccaaggct tcctagaaat tgaaatcttt gcctaggcag
     2101 agaaattgac ctatggtggc ttattttagt cttttataaa taaactgagt ttttgatagg
     2161 gtaacttatg gattgactag attcatatca ctttctcctc taaaatattg tagtattttc
     2221 ttatagttat aactcaaaaa tatcaagcag acagagaatt taggcagtgc aaaggagtat
     2281 tcttgtgtgt ttgtgttgag tcattctgtc cattcctcca ccagctcctg ggcaccacct
     2341 gagaaaccgt gctctctaag tttgttctct gctttgaccc cacttttata gctgtctttg
     2401 catctttgat aaaacttcca cttgaatttg gcactgataa taattattgc ttatgaaagt
     2461 ttgtgaatta agttctttat aaagggtaaa aagctgtata ttgctgggtt ttgttgtttt
     2521 tttgttttgt ttttttttgt tttttgtctg tgtaagatta taaagaaatg tgcctaaagt
     2581 attcttttct ggaataattt gtatgttctt ttataaagat atggattggt ttaccagctg
     2641 tttaaaaaaa aaaacatgtg tcctagctgg gcatagtggt gcataccttt aatcccagca
     2701 cttgggaggc agaggcaggt gaatttctaa gttcaaggcc agcttggtct atagagtgag
     2761 ttccaggaca gccaggacta cacagagaaa ccctgtctca aaaaaaccaa ccaaacaaaa
     2821 acaaaaacaa aatgtgtcct acttaattgg tatatgtgtt tttcaaacaa tcatttgagg
     2881 ggtgttttga tttggtttgg tttttgtttc tgtctttttg gtccattcat tcactgttta
     2941 aaagtttatg attcttccaa aaatgaatat agtttccttt ttcaaatctg aaggcatgtg
     3001 ggaagcagtg agcaaaacct gtggttatta acggaaaagt cttttattac aaagtcaatt
     3061 aaaacttttc attcaaggtt tttgagccaa actagaagtt gagattgtaa aactgcttta
     3121 agaactttaa agaaatgaat atttgatctc tgattaattt ttgagacttc taaatctctt
     3181 cttgttttaa gtttcttgga cttctgacaa acttccctgg agaagtgttc atttttgttt
     3241 tcttcatgta gcttgtagat cataataagt atttgctctt aaaatttact acttagtagc
     3301 atgattattt ttgttctgtt gatgaagcaa atttgacaga atattatttc tccatatcac
     3361 acatatctac actattatct gataacacac tggtagtttt taagactaag gcagtttata
     3421 gaatgaagta tatcaatatt cttttggttt cccaaagcaa tattttactt ttcatttatt
     3481 atagtttgaa agacattttt cattgttcca ttacctatag aaatggtatt tcatgaccta
     3541 gggaaaaagg aattactcct ttttgtagac tcatacctga aagcagtgat ttactagaat
     3601 tgctttgtgt ggctactaag tttattttgt caaaaatgac aaggaaaaag ccagctgttt
     3661 tcatagacct tttcattatg atactgtatc ttgcatagtt gaatcttctc atttatacag
     3721 tgcctttttc tcatgctcat tgtctactga ctttaaggca ggcaacactg gaccatagtg
     3781 gtgcaggcct tctattgagg ccagaggagc aagtgtgctt cttccttgtc cttgtcccat
     3841 cattgagacc ttcatctaca gtttccaaac agtcattgga aaacgcacga cagttaccca
     3901 gaaggtttta tttctcagca gatttgtaga atgaagtata acgtcagtga atgagagtcc
     3961 aagttcttat cacacgatat taggtactaa ttataccctc attgctttaa aatacacatc
     4021 agggtctctt ttaaaaatag aacaaatctg tagtatttaa gtttaaaaat cttaagttta
     4081 ttatgttaaa ttgaattttg tcaacccttc tttttaaatt aaaataattg aatagagtgc
     4141 ctagttaaat tttctcaaag caaggtaact gctcagctca gtcagctgtg gcaagctggc
     4201 cagccctctt cactccagcg ttcttcactg ctctatgtct gcttacacag cttggacatg
     4261 gctgctttcc atgaaggaaa tataggggag gtggactgta agggatatat aaccagtgtg
     4321 aagaactgct tcataaaata tgtattaagt attgtatttc cctcttagca gttgaatcca
     4381 aaccagtttc atttagctgg aagtagacag gaaggagctg ccttaagcac tttagaaaaa
     4441 gaatttgcta caattcattt gactcagctg attgtgtcac atcttttaaa tactggtaaa
     4501 tatggatata ccaagtattt aatgactaat gcacatagaa attaatatta atacagtgat
     4561 cttttgaatg ttccaggtat aggcttttta aaaagtgtta agagtgtctg tctgtctgtc
     4621 tgtctgtctg tctgtctgta cgtttaattg atagcacctc tgccgtgtgt catcaactac
     4681 tagacagcca ggctaagcct tctcattctg ttctgaagat tctaaaaaaa ttcgaaccat
     4741 caacaatagt atgtataatt tgaacttcca tgattgatcc ttgatataaa taataaaaga
     4801 aaatatttat gatgaaatat tttaattagg tcaattatct agaattacct agttttgtct
     4861 atatatcttt tccatgaaat tatagctatc tatgtatttg tagttgtttc tttcaaaaac
     4921 aatttttaaa aattggaaag ggatatatat gagaagtgat tactccaaag aatattaatc
     4981 ttaaaagaaa gcagtataga tgtcttacca tgaaatacat tactctaggc taaaatttca
     5041 actgttttag tcatagattt ttagcatctt tgttagatca gcatataatt catataacta
     5101 cttaagtttt tatgatgtat catcaatttt attactttct gtctatgttt gcaaaagtag
     5161 tagagtttaa ttcaccatat gaacctcatt ctgatgtttt tgatttgata gtcttgatct
     5221 aaaaataatg ttttgttaat atgtcactaa atttctaaaa actgtattca tgggctgctg
     5281 agatggctca caagaaaagc acttgctgcc aactggatga cttgagtttg ttccctggga
     5341 cccaaatgga aggggagact tatctcctgc aagttgtctt ttaacctgcg catgtgtgtg
     5401 cacatgtgca tgcgcataca cacacacaca cacacacaca cacatacctt aaaaattttt
     5461 taaagtacat ttgttgttgc ttgtaaatta actactcgta gtaatatttc acttttacat
     5521 tataataaaa agtttggaaa agttactttt cttgttttat ttttacatca tattcattct
     5581 gtcagaagta agcatgaaat tactcagtat ccatgtcacc accaagttgt tgttttcaag
     5641 ccagtatatt ttttcataac tccagtgctc agacctagag taataaagct tttcttacag
     5701 aaaaccatca cagcgacatt acctcatgtt tgtatgttta gttttgtgtc tcgtaacagt
     5761 gttcacattt gtgattctga tgtcagtatt gtgtcacctg agcgggatga ttacctgagt
     5821 accataggaa ctttgtacca gttggaattt aagtggactg tttgctgctt ttgttcgcat
     5881 tggaacgttg gacatgccat atgatactgg cttagtaatc aataccagta attaccatag
     5941 aactttatct gactacccaa ccatatcaaa agagtacttt tttctgggtt aataatacta
     6001 gctttgatac ataatcattt aagttatatt tgtttaaaat tatatatttt cttagtaata
     6061 gtcaagttgg tgcttaggaa taaacatgta gaagtttatg cagtatgtag ggcagaggtc
     6121 agtgaatgta tttgcttggc ttggaactta agattgaacc aattttacaa taaatcaaat
     6181 tggaagaaat tggtaaaagg cattttagta atattggaac tttttgaagt gtgtgggact
     6241 atgagaagaa tttcttacta acatttccaa tatctgtaag ataccaaagg actgagacta
     6301 actgatcttt taatggaatt tctttgaaat caaatccata actgattcta ttaagataca
     6361 atagctaaag ttggggaata acttcaggta aaaactgcaa gtcttgaaga tttttggcat
     6421 tcttttaagt atttaaactt aatctttata gctgccccat acagtaatct atgacctctc
     6481 tgaatcactc ttcaatcttg ggcctctatt gccttacttc aaatattgta ccttgtttag
     6541 cctacctcac agggctgttg tgaggagtgt agtgaaacgg actctcatgt gaactgggtg
     6601 gtttccacta agaatggttg tgtttggata cttgtaaatg ctgtttagtt agaaaaagca
     6661 tgttaagttg gtataagcag tgattttaaa tgatttttaa aaataagacg tccttcaaaa
     6721 tgtcttttag tatcaattaa gtttgtgcat gattgttttt atatttctca tcaactacac
     6781 aacttttcca agttataaag tctactgcag cattcatgtg tagcggggaa gcctacgtaa
     6841 gcaaacgact acagctcctt ccccccagga cttgcacttg cactagagca gccggtgccc
     6901 atgcagagtg aacgtggctg aattaacttt tccaacaacc aagtgggtca gcaatttgat
     6961 gcccttgata aatatcaact ttattgaatt gtacctttta ttaaaaagga aatacttcaa
     7021 aaccttgttc attacctaga ccagttatta tctgtctgga catagttgtg ttcctctaaa
     7081 ttggatgtac taaatagttt acaagttatc ctactccaca gattttggta tgtttgttat
     7141 ctggacatga ttttgctatg cagttgtgat aataaaaatt ccagctcctc aggtttaacc
     7201 tctaagttgt ggatggagac tatttaaagt acacatgatg tattcagtgc tgcaagagtg
     7261 tttgaaatga gcacactgcc tcattttcct caccaacaag acaaagcctt tccaatgatt
     7321 tttttttaaa ctttcaaagt ggttgttcaa agtgtagcaa cttgtatgtt gaaatgattg
     7381 tatgttctgt atgaaatgtt ccacttgaga tttttacaaa agcacctgta ttatctcttt
     7441 taaaaattaa actttttttt tgctttcaaa aaaaaaaaaa aaaaaaaaaa a
//
