LOCUS       NM_183178               1784 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus fibronectin type 3 and SPRY domain-containing protein
            (Fsd1), transcript variant 1, mRNA.
ACCESSION   NM_183178 XM_973706
VERSION     NM_183178.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Baneyx,G., Baugh,L. and Vogel,V.
  TITLE     Fibronectin extension and unfolding within cell matrix fibrils
            controlled by cytoskeletal tension
  JOURNAL   Proc Natl Acad Sci U S A 99 (8), 5139-5143 (2002)
   PUBMED   11959962
  REMARK    GeneRIF: Fibronectin extension and unfolding within cell matrix
            fibrils controlled by cytoskeletal tension
REFERENCE   2  (bases 1 to 1784)
  AUTHORS   Carim-Todd,L., Escarceller,M., Estivill,X. and Sumoy,L.
  TITLE     Characterization of human FSD1, a novel brain specific gene on
            chromosome 19 with paralogy to 9q31
  JOURNAL   Biochim Biophys Acta 1518 (1-2), 200-203 (2001)
   PUBMED   11267680
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT009719.10.
            
            On Aug 23, 2022 this sequence version replaced NM_183178.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK140132.1, BC055106.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-179               CT009719.10        30663-30841
            180-275             CT009719.10        31931-32026
            276-407             CT009719.10        32312-32443
            408-509             CT009719.10        32862-32963
            510-532             CT009719.10        34400-34422
            533-654             CT009719.10        34607-34728
            655-864             CT009719.10        35355-35564
            865-963             CT009719.10        38031-38129
            964-1123            CT009719.10        39545-39704
            1124-1203           CT009719.10        40046-40125
            1204-1455           CT009719.10        40260-40511
            1456-1544           CT009719.10        40609-40697
            1545-1784           CT009719.10        40830-41069
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 29.1 cM"
     gene            1..1784
                     /gene="Fsd1"
                     /note="fibronectin type 3 and SPRY domain-containing
                     protein"
                     /db_xref="GeneID:240121"
                     /db_xref="MGI:MGI:1934858"
     exon            1..179
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..1655
                     /gene="Fsd1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     fibronectin type III and SPRY domain-containing protein 1"
                     /codon_start=1
                     /product="fibronectin type III and SPRY domain-containing
                     protein 1 isoform 1"
                     /protein_id="NP_899001.1"
                     /db_xref="CCDS:CCDS37661.1"
                     /db_xref="GeneID:240121"
                     /db_xref="MGI:MGI:1934858"
                     /translation="MEDQREALRKIITTLAMKNEETQTFIYSLKQMLLNVEANSAKVQ
                     EDLEAEFQSLTSVLEELKESMLMKIKQDRASRTYELQNQLAACTRALESSEELLETAN
                     QTLQASDSEDFSQAAKEIKDGITMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALK
                     FLPVPSAPTIDLAESLVSDNCVTLVWHMPDEDSKIDHYVLEYRKTNFEGPPRLKEDHP
                     WMVVEGIRQTEHTLTGLKFDMKYMNIRVKACNKAVAGEFSEPVTLETPAFMFRLDGST
                     SHQNLRVEDLSAEWDAMGGKVQDIKAREKEGKGRTASPVNSPARGTPSPKRMSSGRGG
                     RDRFTAESYTVLGDTLIDGGEHYWEVRFEPDSKAFGLGVAYRSLGRFEQLGKTAASWC
                     LHANNWLQASFTAKHANKVKVLDSPVPDCLGVHCDFHQGLLSFYNARTKQLLHTFKAK
                     FTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQKRGSATSSSNTSLT"
     exon            180..275
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            276..407
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            408..509
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            510..532
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            533..654
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            655..864
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            865..963
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1123
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1203
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1455
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1544
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1784
                     /gene="Fsd1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1764..1769
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fsd1"
                     /note="hexamer: AATAAA"
     polyA_site      1784
                     /gene="Fsd1"
                     /note="major polyA site"
ORIGIN      
        1 gtagtacatg tagtgatgga gcgctgagca gggggcgcgg cggcggaggc ggcgagggca
       61 cggaaggcta gttggctgct gtctgcgtcc aaggaacttt aagggtttgg agaaccagct
      121 gaaggggacc cgcggccagg ccaaggcaac agggggctgc aactatggaa gaccagaggg
      181 aggcgctaag aaaaatcatc actaccctgg ccatgaagaa tgaggagacg cagaccttca
      241 tctactccct gaagcagatg ttgctgaatg tagaggcaaa ctcagccaaa gtccaggagg
      301 atctggaagc cgagttccag tccctcacgt cggttctgga ggagctgaaa gagtccatgc
      361 tgatgaagat caaacaggac agggccagcc gcacctacga gctgcagaac cagctagctg
      421 cctgcacacg agccctggag agctccgagg agctcctgga aacagccaac cagaccctgc
      481 aggcttcaga cagcgaggac ttcagtcagg ccgccaagga aatcaaagat ggcataacta
      541 tggcccctgc cttccgacta tcgctcaaag ccaaggtgag cgacaatatg agtcacctca
      601 tggtggactt cgcccaggaa aggcagatgc tacaggccct caagttccta cctgtgccca
      661 gcgcccccac catcgacttg gcagagtccc tcgtgtcaga taactgtgtg acgctggtat
      721 ggcacatgcc agatgaggac agcaagatcg accactatgt gctggagtac cgcaagacca
      781 atttcgaggg cccaccccgc ctcaaggagg accacccctg gatggttgtc gagggcatcc
      841 ggcagaccga gcacaccttg acaggtctca aatttgacat gaaatacatg aacattcgtg
      901 tgaaagcctg taacaaggcg gtggctggtg aattctccga gccggtgacc ttagagacac
      961 cagcattcat gttccgcctg gacgggtcca catctcacca gaacctgcga gtggaagatc
     1021 tctctgccga gtgggacgcc atgggcggga aggtccaaga tatcaaggct cgagagaaag
     1081 agggcaaggg acggaccgca tcccctgtaa actctccagc cagagggact ccatctccca
     1141 agaggatgtc ctcaggtcgt gggggccggg accggttcac agctgagtct tacacggtgc
     1201 tgggggacac actgattgat ggtggcgagc actactggga ggtgcgcttc gaaccagaca
     1261 gcaaggcctt tggcttgggt gtggcctacc gcagcctggg ccgattcgag cagctgggca
     1321 agacggctgc atcatggtgc ctgcatgcca acaactggct gcaggccagc ttcaccgcca
     1381 agcacgccaa caaggtcaaa gtgctggaca gccctgtgcc tgactgcctg ggtgtgcact
     1441 gcgacttcca ccaaggcctc ctatctttct acaatgcccg caccaaacag ctcctgcaca
     1501 ccttcaaggc caagttcacg cagcctctgc ttccagcctt caccgtatgg tgtggaagct
     1561 tccaggtgac aacaggcctg caggtgccca gtgccgtgcg ctgcctgcag aagcggggca
     1621 gtgccactag cagttccaat accagcctca cctaggccag gccatctacc agctggggtg
     1681 cttcagccca gcttcttctt tctgctgctt ggagccttaa ctctggaagg gagggtcagg
     1741 gttccctccc cacctcactc tataataaag ataaaacact ggtc
//
