LOCUS       NM_001163271            3566 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus fibrous sheath CABYR binding protein (Fscb), mRNA.
ACCESSION   NM_001163271 XM_887483 XM_916221
VERSION     NM_001163271.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3566)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3566)
  AUTHORS   Sun,J., Lu,Y., Nozawa,K., Xu,Z., Morohoshi,A., Castaneda,J.M.,
            Noda,T., Miyata,H., Abbasi,F., Shawki,H.H., Takahashi,S.,
            Devlin,D.J., Yu,Z., Matzuk,R.M., Garcia,T.X., Matzuk,M.M. and
            Ikawa,M.
  TITLE     CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or
            epididymis-enriched genes individually dispensable for male
            reproductiondagger
  JOURNAL   Biol Reprod 103 (2), 183-194 (2020)
   PUBMED   32588039
REFERENCE   3  (bases 1 to 3566)
  AUTHORS   Zhang,X., Chen,M., Yu,R., Liu,B., Tian,Z. and Liu,S.
  TITLE     FSCB phosphorylation regulates mouse spermatozoa capacitation
            through suppressing SUMOylation of ROPN1/ROPN1L
  JOURNAL   Am J Transl Res 8 (6), 2776-2782 (2016)
   PUBMED   27398160
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3566)
  AUTHORS   Liu,S.L., Ni,B., Wang,X.W., Huo,W.Q., Zhang,J., Tian,Z.Q.,
            Huang,Z.M., Tian,Y., Tang,J., Zheng,Y.H., Jin,F.S. and Li,Y.F.
  TITLE     FSCB phosphorylation in mouse spermatozoa capacitation
  JOURNAL   BMB Rep 44 (8), 541-546 (2011)
   PUBMED   21871179
  REMARK    GeneRIF: FSCB contributes to spermatozoa capacitation.
REFERENCE   5  (bases 1 to 3566)
  AUTHORS   Li,Y.F., He,W., Jha,K.N., Klotz,K., Kim,Y.H., Mandal,A., Pulido,S.,
            Digilio,L., Flickinger,C.J. and Herr,J.C.
  TITLE     FSCB, a novel protein kinase A-phosphorylated calcium-binding
            protein, is a CABYR-binding partner involved in late steps of
            fibrous sheath biogenesis
  JOURNAL   J Biol Chem 282 (47), 34104-34119 (2007)
   PUBMED   17855365
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR974484.9.
            
            On or before Jul 15, 2009 this sequence version replaced
            XM_916221.3, XM_887483.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3566              CR974484.9         84618-88183
FEATURES             Location/Qualifiers
     source          1..3566
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 26.96 cM"
     gene            1..3566
                     /gene="Fscb"
                     /gene_synonym="EG623046"
                     /note="fibrous sheath CABYR binding protein"
                     /db_xref="GeneID:623046"
                     /db_xref="MGI:MGI:3646964"
     exon            1..3566
                     /gene="Fscb"
                     /gene_synonym="EG623046"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..3397
                     /gene="Fscb"
                     /gene_synonym="EG623046"
                     /note="PKA phosphorylated calcium and CABYR-binding
                     protein"
                     /codon_start=1
                     /product="fibrous sheath CABYR-binding protein"
                     /protein_id="NP_001156743.1"
                     /db_xref="CCDS:CCDS49073.1"
                     /db_xref="GeneID:623046"
                     /db_xref="MGI:MGI:3646964"
                     /translation="MEECEEPEEPISLGRQEYRRRRRPSQPMVDKSQQTEITEKRKAM
                     ASVQPPAPKATHSIGNIPGSKDNYSRKEYESLRLSSQLQKTLMKRKHVQDMTDKSLQT
                     EPIVEEKVEVIFIDKTLKLEENTAGVGEIAPELPQSIPEVEIPTSRPTSHLIDRSQQT
                     SCTGDWSLIYICPKEKVDKEQQTYFSELEIIIRSIPGSSMTKSKEETIPIAQEDPLVE
                     INGSLEIEVLSPEELPDVMMSFTEGEISGELQALSNGEATVKGELFLTEEIPIQAPSP
                     AEETSAAETATTTAKDVVDIQAPPADKLSSVEAPADISPTLVQGALSDKPSDQQYPQG
                     TEMAPSELPVEDLDPFSEEVLEKVQALTTDSMLEDLGIAESTIAEETSGKVQHPLSEE
                     TSKEVPAEVHFPIAADFEESAILINEKFATDEVFEEYKPPIIEEVSADKATAEVQPPS
                     AEDASEEVAPSEVLPPSTEQGTVEDLTAEVLSTPTEEGPTEVPPQPTEEGPAEVPPPL
                     SEEGPAEVPPAPAEEAPAEVLPPPAEEAPAEVPPPLTEEGPAEVPPTLTEEGPAEVPL
                     APAEEVPAEVLPPPAEEVPAEVPPPLTEEGPAEVPPPLTEEGPEEVPPLPAEEAPTKV
                     PPSPAEKGSAEVSPPQTEEGPAEVPPPPAEEFPTEVPSSSAEEGSSEVPLPPTAERPE
                     EAPPPATEEAPVEVLPPATEEAPVEVQSPAAEEGLAEVPPPPTEESPTHDVPTEVQVP
                     QAKESPGQVLPLSGESTAEEASAQVQPPSFEKAPLESLPLEEVEKIHLDNLPFEVQPL
                     PTEDIAIGVPAESQALPADENPAREDTVETQPSSFEGAPIAENPIEAPLPASEADTGR
                     EDSAVHPSSLAPTDEAPAEIQILQTDDIPTEMSPVENQPLPAEEGFPEVVSEEEATAA
                     EVRFPLSEGAPAQEATVEAQLTSVEESPKRASVDVQPLSPETPVEESPGVDLPLKTNE
                     VTMQEFRVEKMPAEDPLPPSEQTPADQVLLKEHRLSQVADISEKELESTTLTSDKMSE
                     GIDSVPEDVSGTKDDQISTFKIEGTIKIELKN"
ORIGIN      
        1 agaaacaaac caagaaagaa gatgaatgag taaggttgga tccaacagga gtgtagtcaa
       61 ggatggtata attcatgaat tattttttct tgagctcaat ttaaaaaaag tcaatgaagg
      121 aaggcaaagg tgtaaccatc tggtacattt atgattctta atgattaatt gattgaactg
      181 ataaatttgg atatcatcag tcatagaaat ggaagaatgt gaagaacctg aagagcctat
      241 atcattagga aggcaggaat atagaaggag aagacgaccc agccaaccaa tggtagataa
      301 gtcccagcaa actgaaataa cagaaaaaag gaaagccatg gcttcagtac aacctcctgc
      361 ccctaaagct actcatagta ttggtaatat tcctggaagt aaagacaact actctcgaaa
      421 agaatatgag tctcttaggc tgtcctctca acttcagaaa actttgatga agagaaagca
      481 tgtccaggat atgactgaca aatctcttca gacagaacct attgtggaag aaaaagtgga
      541 agttatattc attgataaaa cacttaaact tgaagaaaac acagctggtg ttggagaaat
      601 agctcctgaa ttgccacaga gtattccaga agtagagatt ccaacaagca gacccaccag
      661 tcatttaata gacagatctc aacagaccag ctgtactggt gactggagcc tgatatacat
      721 ttgcccaaaa gaaaaagtgg acaaagaaca acagacctac tttagtgagt tagaaattat
      781 tatcaggtct attccaggta gctccatgac taagtcgaag gaagaaacaa ttcctattgc
      841 acaagaagat cctttggttg aaataaatgg ttctcttgaa atagaggtac tatcacctga
      901 agaacttcct gatgtcatga tgtctttcac tgaaggggag atttctggtg aattacaggc
      961 tctatcaaat ggtgaggcca cagttaaagg agagctcttc ttgacagagg agatccctat
     1021 ccaagcacca tctccagctg aagagacctc tgcagctgag acagccacta caactgcaaa
     1081 agacgttgtg gatatacagg ctccaccagc tgataagctt tcttctgtag aggctcctgc
     1141 tgatattagt cctacattag tgcaaggggc tctttcagac aagccttctg atcaacagta
     1201 tcctcaaggt actgagatgg ctccttcaga acttcctgtt gaagatctgg atccattctc
     1261 agaagaggtg cttgagaaag ttcaagcttt aacaactgac tctatgcttg aagacttggg
     1321 aatagcagag tctactattg ctgaagagac atctggtaaa gttcaacatc ctctgtctga
     1381 agagacttct aaagaagtac ctgctgaagt tcattttccg atagctgcag actttgaaga
     1441 aagtgctatt ttaataaatg agaaatttgc tactgatgag gtctttgaag aatataagcc
     1501 tccaataatt gaggaagtct ctgcagataa ggctactgca gaagttcagc ctccatcagc
     1561 agaggatgct tctgaagaag tggctccttc agaagttctg cctccatcaa ctgaacaggg
     1621 aactgtagaa gacctgactg cagaagttct atctacacca actgaggagg gccctacaga
     1681 agttccacct caaccaactg aagaggggcc tgcagaagtt ccacctccac tatctgaaga
     1741 ggggcctgca gaagttccac ctgcaccagc tgaggaggcc cctgcagaag ttctgcctcc
     1801 accagcagag gaggcccctg cagaagttcc acctccacta actgaagagg ggcctgcaga
     1861 agttccacct acactaactg aagaggggcc tgcagaagtt ccacttgcac cagctgagga
     1921 ggtccctgca gaagttctac ctccaccagc agaggaggtc cctgcagaag ttccacctcc
     1981 actaactgaa gaggggcctg cagaagttcc acctccatta actgaagagg gccctgaaga
     2041 agttccacct ttaccagctg aagaggcccc tacaaaagtg ccaccttcac cagctgagaa
     2101 gggctctgct gaagtttctc ctccacaaac tgaagagggg cctgcagagg ttccacctcc
     2161 accagctgag gagttcccta cagaagtacc atcttcatca gctgaggagg gctcttctga
     2221 agttccactt ccaccaactg cagagagacc tgaagaagct ccacctccag caactgagga
     2281 ggcccctgta gaagttctac ctccagcaac tgaggaggcc cctgtagaag ttcaatctcc
     2341 agcagctgaa gagggccttg cagaagtccc acctccacca actgaggaga gccctacaca
     2401 tgatgttccc acagaagttc aggttccaca agctaaggaa agtcctggac aggtcctacc
     2461 tttatcaggt gagtccactg ctgaagaagc ctctgcacaa gttcagcctc catcctttga
     2521 gaaggctcct ttagaaagtc ttcctctaga agaagttgag aagatccatt tagataattt
     2581 accatttgaa gtgcaacctc tgccaactga ggacattgca ataggtgtac cagctgaatc
     2641 tcaggctctt ccagctgatg aaaatcctgc aagagaggac actgttgaaa cacagccttc
     2701 atcatttgag ggtgctccaa tagcagaaaa ccctattgaa gctccacttc cagcatctga
     2761 ggcagatact ggaagagagg attctgctgt tcatccttcg tcattagctc ctacagacga
     2821 ggctcctgca gaaattcaga ttctacaaac tgacgatatt cctacagaaa tgtcaccagt
     2881 tgaaaatcag cctctaccag ctgaggaagg ctttcccgaa gtggtctcag aagaagaggc
     2941 cactgcagct gaagttaggt ttcctttatc tgagggggct cctgcacaag aagccactgt
     3001 ggaagcacaa ttaacatcgg ttgaagagag ccctaaaagg gcttctgttg atgtccagcc
     3061 tttatcacct gagacccctg tagaagagtc tcctggtgtt gatctgcctt taaaaactaa
     3121 cgaggttact atgcaagagt ttcgtgtgga aaagatgcct gctgaagatc cacttccacc
     3181 ttcagaacaa acccctgcag atcaggttct actaaaagaa catcgattgt cccaggtagc
     3241 agacatctca gagaaagaat tagagtctac tactttgaca agtgataaaa tgtctgaagg
     3301 aatagattcg gttcctgaag atgtgtctgg aaccaaggat gatcagatct ccactttcaa
     3361 aatagaaggt accattaaaa tagagttaaa gaactgagct atcgtcaggt gttaacttaa
     3421 actaataatt taattggatt ctagaaggtc attctttaga aaatgagatg ctatctggaa
     3481 gaactcttat gaatacatta aagtaaaagg atccctaaaa cgattaagca tacaggttgg
     3541 acaatgaata aaagcagtca caatgt
//
