LOCUS       NP_082470               3007 aa            linear   ROD 30-APR-2024
DEFINITION  protein furry homolog-like [Mus musculus].
ACCESSION   NP_082470
VERSION     NP_082470.2
DBSOURCE    REFSEQ: accession NM_028194.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 3007)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 3007)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 3007)
  AUTHORS   Perez-Garcia,V., Fineberg,E., Wilson,R., Murray,A., Mazzeo,C.I.,
            Tudor,C., Sienerth,A., White,J.K., Tuck,E., Ryder,E.J., Gleeson,D.,
            Siragher,E., Wardle-Jones,H., Staudt,N., Wali,N., Collins,J.,
            Geyer,S., Busch-Nentwich,E.M., Galli,A., Smith,J.C., Robertson,E.,
            Adams,D.J., Weninger,W.J., Mohun,T. and Hemberger,M.
  TITLE     Placentation defects are highly prevalent in embryonic lethal mouse
            mutants
  JOURNAL   Nature 555 (7697), 463-468 (2018)
   PUBMED   29539633
REFERENCE   4  (residues 1 to 3007)
  AUTHORS   Byun,Y.S., Kim,E.K., Araki,K., Yamamura,K.I., Lee,K., Yoon,W.K.,
            Won,Y.S., Kim,H.C., Choi,K.C. and Nam,K.H.
  TITLE     Fryl deficiency is associated with defective kidney development and
            function in mice
  JOURNAL   Exp Biol Med (Maywood) 243 (5), 408-417 (2018)
   PUBMED   29409347
  REMARK    GeneRIF: Fryl protein is required for normal development and
            functional maintenance of kidney in mice.
REFERENCE   5  (residues 1 to 3007)
  AUTHORS   Nakahara,M., Tateyama,H., Araki,M., Nakagata,N., Yamamura,K. and
            Araki,K.
  TITLE     Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from
            MSM/Ms mice
  JOURNAL   Mamm Genome 24 (5-6), 228-239 (2013)
   PUBMED   23604909
REFERENCE   6  (residues 1 to 3007)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK164590.1, BE650071.1, AW489087.1, CJ044706.1, AC108848.12,
            CD550190.1, CD350880.1, BC051118.1 and CD741721.1.
            
            On Dec 27, 2006 this sequence version replaced NP_082470.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3007
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 38.44 cM"
     Protein         1..3007
                     /product="protein furry homolog-like"
                     /note="furry homolog-like"
                     /calculated_mol_wt=337690
     Region          117..649
                     /region_name="MOR2-PAG1_N"
                     /note="Cell morphogenesis N-terminal; pfam14222"
                     /db_xref="CDD:464107"
     Region          687..1860
                     /region_name="MOR2-PAG1_mid"
                     /note="Cell morphogenesis central region; pfam14228"
                     /db_xref="CDD:433790"
     Region          2002..2255
                     /region_name="MOR2-PAG1_C"
                     /note="Cell morphogenesis C-terminal; pfam14225"
                     /db_xref="CDD:464109"
     Region          2285..3007
                     /region_name="Fry_C"
                     /note="Furry protein C-terminal; pfam19421"
                     /db_xref="CDD:466072"
     CDS             1..3007
                     /gene="Fryl"
                     /gene_synonym="2010313D22Rik; 2310004H21Rik;
                     2510002A14Rik; 9030227G01Rik; mKIAA0826"
                     /coded_by="NM_028194.2:599..9622"
                     /db_xref="CCDS:CCDS19337.2"
                     /db_xref="GeneID:72313"
                     /db_xref="MGI:MGI:1919563"
ORIGIN      
        1 mssitidpdv kpgeyviksl faefavqaek kievvmaepl ekllsrslqr gedlqfdqlv
       61 ssmssvaehc lpsllrtlfd wyrrqngtdd esygyrprss tkskgdeqhr erdyllerrd
      121 lavdfifclv lvevlkqipv hpvpdplvhe vlnlafkhfk hkegysgtnt gnvhiiadly
      181 aevigvlaqs kfqavrkkfv telkelrqke qsphvvqsvi slimgmkffr vkmypvedfe
      241 asfqfmqeca qyflevkdkd ikhalaglfv eilipvaaav knevnvpclk nfvemlyqtt
      301 felssrkkhs lalyplitcl lcvsqkqffl nnwhiflqnc lshlknkdpk msrvalesly
      361 rllwvyviri kcesntvtqs rlmsivsalf pkgsrsvvpr dtplnifvki iqfiaqerld
      421 famkeiifdl lsvgkstktf tinpermnig lrvflviads lqqkdgdppm pttgvilpsg
      481 ntlrvkkifl nktltdeeak vigmsvyypq vrkaldsilr hldkevgrpm cmtsvqmsnk
      541 epedmitger kpkidlfrtc iaaiprlipd gmsrtdliel larltihmde elralafntl
      601 qalmldfpdw redvlsgfvy fivrevtdvh ptlldnavkm lvqlinqwkq aaqmynrtqd
      661 sqhgianggp hppplernpy stvfhvvegf alvilcssrp atrrlavsvl reiralfall
      721 evpkgddela idvmdrlsps ilesfihltg adqttllycp ssvdlqtlad wnsspishqf
      781 dvispshiwi fahvtqgqdp wiislssflk qenlpkhcst avsyawmfay trlqllspqv
      841 dinspinakk vnattssdsy iglwrnylvl ccsaatspsp sapagsvrcs ppetlastpd
      901 sgysidskiv gipspsslfk hivpmmrses meiteslvlg lgrtnpgvfr elieelhpii
      961 kealerrpen mkrrrrrdil rvqlvrifel ladagvishs asggldseth flnntlleyv
     1021 dltrqlleae nekdsdtlkd irchfsalva niiqnvpvhq rrsifpqqsl rhslfmlfsh
     1081 wagpfsimft pldrysdrnm qinrhqycal kamsavlccg pvadnvglss dgylykwldn
     1141 ildsldkkvh qlgceavtll lelnpdqssl mywavdrcyt gsrrvaagcf kaianvfqnr
     1201 dyqcdtvmll nlilfkaads srsiyevamq llqilepkmf ryahklevqr tdgvlsqlsp
     1261 lphlysvsyy qlseelaray peltlaifse isqriqtahp agrqamlhyl lpwmnnielv
     1321 dlkplpsgrr qdededdslk drelmvtsrr wlrgegwgsp qatamvlnnl mymtakygde
     1381 lawsevenvw ttladgwpkn lkiilhflis icgvnsepsl lpyvkkvivy lgrdktmqll
     1441 eelvselqlt dpvssgvthm dnppyyrits sckipsvtsg ttsssntmva ptdgnpdska
     1501 lkenfeesyv hldiygglns hlnrqhhrle sryssssggs yeeeksdsmp lysnwrlkvm
     1561 ehnqgeplpf ppaggcwspl vdyvpetasp glplhrcnia villtdliid hsvkvewgsy
     1621 lhlllhaifi gfdhchpevy ehckrlllhl livmgpnsdi rtvasvllrd kefneprvlt
     1681 vkqtahsdyt ftagindftp dyqpspmtds glsssstsss islgnnsaai shlhttllge
     1741 vdlsveqdgk vktlmefits rkrgplwnhe dvssknpsik sadqlatflk hvvsvfkqsn
     1801 aegihlerhl sevalqtals cssrhyagrs fqifralkqp lsadtlsdvl srlvetvgdp
     1861 gedaqgfvie llltlesaid tlaetmkhyd llsalsqssy hdpvmgnkya anrkstgqln
     1921 lstspinssg hlgcngdtrs nslrlslvgd rrgdrrrsnt lditdgrinh ggslartrsl
     1981 sslrekgvyd tqpptepsnl matifwiats llesdyeyey llalrllskl lthlpldkse
     2041 srekienvqs klkwsnfpgl qqlflkgfts vstqemtvhl lsqlisvskh tlvdpsqvsg
     2101 fplnilcllp hliqhfdspt qfcketasri akvcaeekcp tlvnlahmms lysthtysrd
     2161 csnwinvvcr ylhdsfseat fslvtylael lekglssmqq sllqiiysll shidlsaapv
     2221 kqfnleiiki igkyvqspyw kealnilklv vsrsaslvvp ndipkaygvd vgspeisfak
     2281 ifnnvskelp gktldfhfdi setpiignky ggqhsaagrn gkakviavtr stsstssgst
     2341 snalvpvswk rpqlsqrrtr eklmsvlslc gpesglpknp svvfssnedl evgdqqtsli
     2401 sttediiqee evavednsse qqfgvfkdfd fldveledae gesmdnfnwg vrrrsldsid
     2461 kgdtpslqey pcssstpslt ltnqedtdes seeeaaltas qilsrtqmln sdcvtedmmp
     2521 ehqdllqsqd sassnttedv lqirdetpsl eacldnassq lpegtssvlk eehvtafede
     2581 gsyvipdqqd plvcrgildl eetdmpepla pesypesice edvtlalkel derceeeead
     2641 fsglssqeed eqdgfpevqt splptpflsa iiaafqpmay edeeeawrch vnqtlsdtdg
     2701 scavftfhvf srlfqtiqrk fgeitkeavg flgeslqrig tkfksslevm macsecptvf
     2761 vdaetlmacg lletlkfgvl elqehldtyt tkreaaeqwl dnckrtfgan ediyrmntna
     2821 helelcrrly rlhfqllllf qaycklinqv ntikneaevi nmseelaqle gilkeaeaas
     2881 eneeidiska aqttietaih slietlknke fvsavaqvka frtlwpndif gscdddpvqt
     2941 llhiyfhhqt lgqtgsfavi ssnldmsean cklmelnlei reslrtvqsy pllaqtkpvg
     3001 nmtstgf
//
