LOCUS       NM_001081075            1420 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus FRA10A associated CGG repeat 1 (Fra10ac1), transcript
            variant 1, mRNA.
ACCESSION   NM_001081075 XM_129261
VERSION     NM_001081075.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1420)
  AUTHORS   Sarafidou,T., Kahl,C., Martinez-Garay,I., Mangelsdorf,M., Gesk,S.,
            Baker,E., Kokkinaki,M., Talley,P., Maltby,E.L., French,L.,
            Harder,L., Hinzmann,B., Nobile,C., Richkind,K., Finnis,M.,
            Deloukas,P., Sutherland,G.R., Kutsche,K., Moschonas,N.K.,
            Siebert,R. and Gecz,J.
  CONSRTM   European Collaborative Consortium for the Study of ADLTE
  TITLE     Folate-sensitive fragile site FRA10A is due to an expansion of a
            CGG repeat in a novel gene, FRA10AC1, encoding a nuclear protein
  JOURNAL   Genomics 84 (1), 69-81 (2004)
   PUBMED   15203205
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112153.4.
            
            On Jul 25, 2018 this sequence version replaced NM_001081075.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BN000292.1, AK077572.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-191               AC112153.4         41438-41628
            192-268             AC112153.4         43677-43753
            269-364             AC112153.4         45863-45958
            365-410             AC112153.4         46087-46132
            411-487             AC112153.4         49683-49759
            488-571             AC112153.4         51133-51216
            572-656             AC112153.4         52145-52229
            657-702             AC112153.4         58282-58327
            703-816             AC112153.4         60781-60894
            817-859             AC112153.4         64001-64043
            860-978             AC112153.4         65912-66030
            979-1017            AC112153.4         69855-69893
            1018-1096           AC112153.4         75683-75761
            1097-1420           AC112153.4         76790-77113
FEATURES             Location/Qualifiers
     source          1..1420
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 32.82 cM"
     gene            1..1420
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /note="FRA10A associated CGG repeat 1"
                     /db_xref="GeneID:70567"
                     /db_xref="MGI:MGI:1917817"
     exon            1..191
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..1139
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FRA10AC1 homolog"
                     /codon_start=1
                     /product="protein FRA10AC1 homolog isoform 1"
                     /protein_id="NP_001074544.1"
                     /db_xref="CCDS:CCDS37972.1"
                     /db_xref="GeneID:70567"
                     /db_xref="MGI:MGI:1917817"
                     /translation="MHGHGGYDSDFSDDEQGGGSSKKRKKTVEDELLLTKPFQKERHG
                     KVAHKQVAADLLDREEARNRRFHLIAMDAYQRHTKFVNDYILYYGGKREDFKRLGEND
                     KTDLDVIRENHRFLWNEEDEADMTWEKRLAKKYYDKLFKEYCIADLSRYKENKFGFRW
                     RIEKEVISGKGQFFCGNKCCNEKEGLRSWEVNFGYTEHGEKRNALVKLRLCQECSFKL
                     NFHHRRKEIKSTKKKSKTTPECDESPRKKSRSPPSEEASKGKDEGHSSSKKSEDSRNR
                     NAEEEDSASDSELWKGPLPETDEKSQEEEFDDYFQDLFL"
     exon            192..268
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            269..364
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            365..410
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            411..487
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            488..571
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            572..656
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            657..702
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            703..816
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            817..859
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            860..978
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1017
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1096
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1420
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1392..1397
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1420
                     /gene="Fra10ac1"
                     /gene_synonym="5730455O13Rik"
                     /note="major polyA site"
ORIGIN      
        1 agcggttccc agccggtacc cgtagggcca ggcgtgcagc gtgcggtgac agtggcgcgg
       61 gcggcggcgc tgcgtggctc tggaggaccg gcgcggacct gcagcggctc gctgaggccg
      121 tggctcgtcg ctgcagctgt caggactctt gggggcgaac ttgccagaca gagaagagcg
      181 gaagggaagg gatgcatggg catggaggct atgactctga ttttagtgac gatgagcaag
      241 gcggaggctc cagcaaaaag aggaagaaga cagtcgaaga tgagttgctg cttacaaaac
      301 cgtttcaaaa agaaaggcat ggaaaggtgg cccataaaca agtcgccgca gacttgctcg
      361 acagggaaga agcaagaaat agaaggtttc atctcatagc tatggatgct tatcaaaggc
      421 acaccaagtt tgtaaacgac tatattttgt actatggtgg caaaagagag gactttaagc
      481 ggttggggga gaatgataag acagatctgg atgttatacg agaaaatcat agattccttt
      541 ggaatgagga ggatgaagca gatatgactt gggagaagag acttgcaaag aaatactatg
      601 ataaattatt caaggaatac tgcatagctg atctcagtag atacaaagaa aataagtttg
      661 gatttaggtg gcgaatagaa aaagaagtaa tttcaggaaa aggccagttt ttttgtggaa
      721 ataaatgttg taatgaaaaa gaaggcctga ggagctggga agtcaacttc ggttacactg
      781 agcacggtga aaagagaaac gcacttgtta aattaagatt atgccaagaa tgttccttta
      841 aattaaattt tcatcacagg agaaaagaaa tcaagtcaac aaagaaaaag tctaaaacca
      901 cgcctgagtg tgacgagtca cctcgtaaga aatccagatc gccaccttca gaggaagctt
      961 ccaaggggaa ggatgaagga cattcatcct caaagaagtc agaagattct agaaacagaa
     1021 acgctgagga ggaagacagt gcttcagact ctgagctctg gaagggtccg ctgccagaga
     1081 cagatgagaa gtcccaggaa gaagaatttg atgattattt tcaggatttg tttctgtgaa
     1141 ctgggagaga gaatcttatt ccttggtgag gagatgtaca gagacactcg gtgagtgtgt
     1201 ccatgctgtt gagtctggac agccactggg atagatcctt cagcagcacg ggacatttca
     1261 gacatttcct cctttacttt cgtggctgct cggctgctta tctaaaacct ggttttggct
     1321 ctagctctac agtttatggt atacttgttt caagtgtcat ttgaacatgg agtgattgtc
     1381 attgagctgt aaataaatta tttagtgtct tattctaaaa
//
