LOCUS       NM_008042               1220 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus formyl peptide receptor 3 (Fpr3), mRNA.
ACCESSION   NM_008042
VERSION     NM_008042.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1220)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1220)
  AUTHORS   Yu,T., Yu,Y., Ma,Y. and Chen,G.
  TITLE     FoxO4 mediates macrophage M2 polarization by promoting LXA4R
            expression in an ovalbumin-induced allergic asthma model in mice
  JOURNAL   Allergol Immunopathol (Madr) 51 (4), 19-30 (2023)
   PUBMED   37422776
  REMARK    GeneRIF: FoxO4 mediates macrophage M2 polarization by promoting
            LXA4R expression in an ovalbumin-induced allergic asthma model in
            mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1220)
  AUTHORS   Zharkova,O., Salamah,M.F., Babak,M.V., Rajan,E., Lim,L.H.K.,
            Andrade,F., Gil,C.D., Oliani,S.M., Moraes,L.A. and Vaiyapuri,S.
  TITLE     Deletion of Annexin A1 in Mice Upregulates the Expression of Its
            Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in
            Platelets
  JOURNAL   Int J Mol Sci 24 (4), 3424 (2023)
   PUBMED   36834844
  REMARK    GeneRIF: Deletion of Annexin A1 in Mice Upregulates the Expression
            of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic
            Peptide in Platelets.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1220)
  AUTHORS   Wickstead,E.S., Karim,H.A., Manuel,R.E., Biggs,C.S., Getting,S.J.
            and McArthur,S.
  TITLE     Reversal of beta-Amyloid-Induced Microglial Toxicity In Vitro by
            Activation of Fpr2/3
  JOURNAL   Oxid Med Cell Longev 2020, 2139192 (2020)
   PUBMED   32617132
  REMARK    GeneRIF: Reversal of beta-Amyloid-Induced Microglial Toxicity In
            Vitro by Activation of Fpr2/3.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1220)
  AUTHORS   Perniss,A., Liu,S., Boonen,B., Keshavarz,M., Ruppert,A.L., Timm,T.,
            Pfeil,U., Soultanova,A., Kusumakshi,S., Delventhal,L., Aydin,O.,
            Pyrski,M., Deckmann,K., Hain,T., Schmidt,N., Ewers,C., Gunther,A.,
            Lochnit,G., Chubanov,V., Gudermann,T., Oberwinkler,J., Klein,J.,
            Mikoshiba,K., Leinders-Zufall,T., Offermanns,S., Schutz,B.,
            Boehm,U., Zufall,F., Bufe,B. and Kummer,W.
  TITLE     Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary
            Clearance in Response to Virulence-Associated Formyl Peptides
  JOURNAL   Immunity 52 (4), 683-699 (2020)
   PUBMED   32294408
REFERENCE   6  (bases 1 to 1220)
  AUTHORS   Wang,Z.G. and Ye,R.D.
  TITLE     Characterization of two new members of the formyl peptide receptor
            gene family from 129S6 mice
  JOURNAL   Gene 299 (1-2), 57-63 (2002)
   PUBMED   12459252
REFERENCE   7  (bases 1 to 1220)
  AUTHORS   Vaughn,M.W., Proske,R.J. and Haviland,D.L.
  TITLE     Identification, cloning, and functional characterization of a
            murine lipoxin A4 receptor homologue gene
  JOURNAL   J Immunol 169 (6), 3363-3369 (2002)
   PUBMED   12218158
  REMARK    GeneRIF: This homologue receptor shows 89% sequence identity with
            murine lipoxin A4 receptor cDNA and functionally responds to LXA4
            as a ligand.
REFERENCE   8  (bases 1 to 1220)
  AUTHORS   Levy,B.D., De Sanctis,G.T., Devchand,P.R., Kim,E., Ackerman,K.,
            Schmidt,B.A., Szczeklik,W., Drazen,J.M. and Serhan,C.N.
  TITLE     Multi-pronged inhibition of airway hyper-responsiveness and
            inflammation by lipoxin A(4)
  JOURNAL   Nat Med 8 (9), 1018-1023 (2002)
   PUBMED   12172542
REFERENCE   9  (bases 1 to 1220)
  AUTHORS   Gao,J.L., Chen,H., Filie,J.D., Kozak,C.A. and Murphy,P.M.
  TITLE     Differential expansion of the N-formylpeptide receptor gene cluster
            in human and mouse
  JOURNAL   Genomics 51 (2), 270-276 (1998)
   PUBMED   9722950
REFERENCE   10 (bases 1 to 1220)
  AUTHORS   Takano,T., Fiore,S., Maddox,J.F., Brady,H.R., Petasis,N.A. and
            Serhan,C.N.
  TITLE     Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable
            analogues are potent inhibitors of acute inflammation: evidence for
            anti-inflammatory receptors
  JOURNAL   J Exp Med 185 (9), 1693-1704 (1997)
   PUBMED   9151906
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC171405.1.
            
            On Feb 1, 2007 this sequence version replaced NM_008042.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: U78299.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1220              AC171405.1         59005-60224         c
FEATURES             Location/Qualifiers
     source          1..1220
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 10.66 cM"
     gene            1..1220
                     /gene="Fpr3"
                     /gene_synonym="ALX; Fpr-rs1; Fpr-s1; Fprl1; LXA4-R; Lxa4r"
                     /note="formyl peptide receptor 3"
                     /db_xref="GeneID:14294"
                     /db_xref="MGI:MGI:1194495"
     exon            1..1220
                     /gene="Fpr3"
                     /gene_synonym="ALX; Fpr-rs1; Fpr-s1; Fprl1; LXA4-R; Lxa4r"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcagtcaa aatggaaacc aactactcta tccctttgaa tggatcagat gtggtgatct
       61 atgattctac catctccagg gttctgtgga tcctctcaat ggtggttgtc tccatcactt
      121 tcttccttgg tgtgctggga aatggactag tgatctgggt agctggattc cggatgccac
      181 acactgtcac cactatctgg tatctgaatc tagcattggc tgacttctct ttcacagcaa
      241 ctctaccatt ccttcttgtt gaaatggcta tgaaagaaaa atggcctttt ggctggttcc
      301 tgtgtaaatt agttcacatt gcagtagatg taaacctatt tggaagtgtc ttcttgattg
      361 ctgtcattgc cttggaccgc tgtatttgtg tcctgcatcc agtctgggct cagaaccacc
      421 gcactgtgag cctggctaga aatgtggttg ttgggtcctg gatttttgct ctcattctca
      481 ctttgcccct tttcctcttc ttgactacag ttagagatgc tagaggggat gtgcactgta
      541 gattgagctt tgtatcctgg ggcaactctg ttgaggaaag gttgaacaca gctatcacgt
      601 ttgtaacaac tagagggatc atcaggttca ttgttagctt cagcttgccc atgtcctttg
      661 ttgccatctg ctatggactc atcactacaa agattcacaa aaaagccttt gttaattcca
      721 gccgtccttt ccgagttctt acaggagttg tggcttcctt ctttatctgt tggtttcctt
      781 tccaattggt ggccctttta ggcacagtct ggctcaaaga gatgcagttt agtggtagtt
      841 ataaaattat tggcaggttg gttaatccaa ccagttcatt ggcctttttc aatagctgcc
      901 tcaatccaat tctctatgtt ttcatgggcc aggactttca agaaagactg attcattccc
      961 tgtcttctcg tctgcagaga gccctgagtg aggactctgg tcatatcagt gatacaagaa
     1021 ccaatttggc ttcacttcct gaagacattg aaataaaggc aatatgagga gggggctgtg
     1081 ggatgtgttt tgtcccacct tagtcccatt ccacttttgt ttcaccttat gctgtgacaa
     1141 gaacattatt aatctgaaaa gtacttctct gtcccccgaa tttgggaaaa aaagtaaaag
     1201 tcaaaggggc ctagaatatt
//
