LOCUS       NM_001168260            4874 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus FAD-dependent oxidoreductase domain containing 2
            (Foxred2), transcript variant 1, mRNA.
ACCESSION   NM_001168260
VERSION     NM_001168260.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4874)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4874)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 4874)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   4  (bases 1 to 4874)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL589650.20 and AL583886.11.
            
            On Jul 15, 2022 this sequence version replaced NM_001168260.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK170795.1, SRR9219383.92048.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               AL589650.20        180932-181171
            241-741             AL589650.20        181551-182051
            742-993             AL589650.20        184106-184357
            994-1260            AL589650.20        185079-185345
            1261-1427           AL589650.20        185504-185670
            1428-1593           AL589650.20        189121-189286
            1594-1835           AL589650.20        190381-190622
            1836-2006           AL589650.20        191891-192061
            2007-3419           AL589650.20        194248-195660
            3420-4874           AL583886.11        1-1455
FEATURES             Location/Qualifiers
     source          1..4874
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 36.92 cM"
     gene            1..4874
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /note="FAD-dependent oxidoreductase domain containing 2"
                     /db_xref="GeneID:239554"
                     /db_xref="MGI:MGI:106315"
     exon            1..240
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     exon            241..741
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..2239
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /note="FAD-dependent oxidoreductase domain-containing
                     protein 2"
                     /codon_start=1
                     /product="FAD-dependent oxidoreductase domain-containing
                     protein 2 precursor"
                     /protein_id="NP_001161732.1"
                     /db_xref="CCDS:CCDS27607.1"
                     /db_xref="GeneID:239554"
                     /db_xref="MGI:MGI:106315"
                     /translation="MGPSGLLVALALHLAVCSRPHRDYCVLGAGPAGLQMAAFLHRAG
                     RDYEVFERESAPGSFFTRYPRHRKLISINKRHTGKANAEFNLRHDWNSLLSDDPHLLF
                     RHYSQAYFPDASDMVRYLGDFARRLGLHVLYNTNITHVTLDKDPQAWNGHYFILTDQK
                     GQVYQCSVLLVATGLAVPKLVDFPGSEYVEGYESVSVDPEDFVGQNVLILGHGNSAFE
                     TAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSLDGLLESDLEY
                     LALVKDSKGKFHVTLKFLLENNSSQSADSIPLPEDDNDNFAMRVAYDRVIRCLGWTFD
                     FSIFDQSLRLSSGTEFSKKYPLIKASYESKGSRGLFILGTASHSVDYRKSAGGFIHGF
                     RYTVRAVHRLLEHRHHGIPWPSTEYPITQLTSSIIRRVNEASGLYQMFSVLADIILLK
                     ENATAFEYLEEFPMQMLAQLEMLTGRTARHGLFVINMEYGKNFSGPEKDVFYYDRSVA
                     HIEDAWMSNFLHPVIYYYRHLPTEQDMRFRPAQWPLPRPTAIHHIVEDFLTDWTAPVG
                     HILPLRRFLENCLDTDLRSFYAESCFLFTLTRQRLPPFCQQGYLRMQGLSSTKSLWQH
                     GVESRLLQDYTAMENSNRWLGDHSTAPEPLTQSLDSNKEEL"
     exon            742..993
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1260
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     exon            1261..1427
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1593
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1835
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..2006
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     exon            2007..4874
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4857..4862
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /note="hexamer: AATACA"
     polyA_site      4874
                     /gene="Foxred2"
                     /gene_synonym="A430097D04Rik; D15Bwg0759e; Gm304"
                     /note="major polyA site"
ORIGIN      
        1 gagtcagccg tagcttccct ccactgcagc ctgtcgtggg agcatcgctg ggctaccggt
       61 ggcggcagcg tgcgggtcgg aagctcagcc tggggaccgc gcacgcgcca gaagcagtgc
      121 gggatagcgg agaccgcggc aggtgtgctg gggcatcctc acgtgatccg gggggctggg
      181 gcggggcctt agaagccaca cctccttcag ggtcccgtac ccccaccccc agggtgaaag
      241 gatgggtccc tcggggctgc tggtggccct agccttgcac ctggcagtgt gttcccgtcc
      301 gcaccgggac tactgcgtcc tgggcgccgg tcctgcgggc ctgcagatgg ccgccttcct
      361 gcatcgagcc ggcagggact acgaggtatt cgaacgcgag tccgcacctg gcagcttctt
      421 cactcgctac ccgcgccacc gcaagctcat cagcatcaac aagcggcaca cgggcaaggc
      481 caacgccgag ttcaacctcc gccacgactg gaactcgctg ctcagcgacg acccacacct
      541 gctcttcaga cactactcgc aggcttactt ccccgacgcc agcgacatgg tgcgctacct
      601 gggtgacttc gcgcggcgcc tggggctcca tgtgttatac aacacaaaca tcacccatgt
      661 gaccctggac aaggatccac aagcctggaa cggccattac ttcattctga cggaccagaa
      721 gggccaggtt taccagtgca gcgtcctgct tgtagccact ggtctggcag tccccaaact
      781 ggttgacttc cccggctctg agtatgtgga ggggtacgag tctgtgtccg tggatcctga
      841 agactttgtg ggccagaatg tgttgatcct gggccatggg aactcagcct tcgagacggc
      901 agaaaacatc ttgggtgtca ctaactttgt ccacatgctg agccgttccc gggtccggct
      961 ctcctgggcc acccactatg ttggagatgt cagagccatc aacaatggcc tgctggacac
     1021 ctaccagctg aaatcactag acgggctcct ggaatcagac ctggagtatc tggccctcgt
     1081 gaaggacagc aagggcaagt tccacgtcac cctgaaattc ctcctggaga ataacagcag
     1141 ccagagtgcc gactctattc ccctccccga ggatgacaac gacaactttg ccatgcgggt
     1201 ggcctacgac cgtgtcatcc gctgcctggg atggacgttt gacttctcca ttttcgacca
     1261 gtccctcaga ctctcctcgg ggactgagtt cagcaagaaa tacccactga tcaaagccag
     1321 ctatgaatcc aaaggaagcc ggggtctctt tatcctaggg actgccagcc actcagtgga
     1381 ctaccggaaa tccgctggcg gcttcatcca tggattccga tacacagtgc gtgctgtcca
     1441 ccggctactg gaacatcggc accatggcat cccctggcca tccacagagt accccatcac
     1501 acagctgacc agctccatca tccggcgtgt aaatgaggct tctgggctgt accagatgtt
     1561 cagtgtgctg gctgacatca tcctgttgaa ggagaacgcc acagcctttg agtacctgga
     1621 ggagttccct atgcagatgc tggcccagct ggagatgctc acagggagga cagcacggca
     1681 tgggctcttt gtcatcaaca tggaatatgg caaaaacttc tctgggcctg agaaggatgt
     1741 cttctattat gaccggtctg tggcacacat agaagatgcc tggatgtcta acttccttca
     1801 ccctgtcatc tactactaca gacacctccc cactgagcaa gatatgcggt tccgtcctgc
     1861 acagtggccc ctgcctcggc ctacagccat ccaccacatc gtggaggact tcctgactga
     1921 ctggacagcc ccagtaggac acatcctccc attgaggcgc ttcttggaaa actgtctgga
     1981 cacagatctg cgtagctttt atgcagagtc ctgtttcctg ttcacactca cacgccagag
     2041 gctgccgccc ttttgccagc agggatacct gagaatgcag gggctctcaa gcaccaagag
     2101 cctttggcag catggtgtgg aaagcaggct cctgcaggac tacacggcca tggagaacag
     2161 caataggtgg cttggtgacc actccacagc tccagagcct ctgactcaat cccttgacag
     2221 caacaaagag gagctctgag catcctcccc cagactatgg tgcctggcac ctctccagaa
     2281 aaccggggaa gcctcttctc ccaccaggac catcacagag ataacagaca atgggactgc
     2341 ccatagagtg cagaaggctg ggttacagtc acagagtggt gtcccttcct gtgctggccc
     2401 ctggtgctag atgcaaggtc aagaggaggg taccttctgt caggtatgag ctgccttcca
     2461 catccagctt gtgtccaact tggaccatca ctaagtaagc accatgctgg ccttgtgtgc
     2521 ctgcttctag gaccagccaa acgccttttc attttccttc tggttcactc tgcagatggc
     2581 cttggcccta cctggggaac atctcaaagc tgaaggcccc tcgtttccac agtgggcata
     2641 tgagagtcaa ggtttagagt cttcagcagt ggggcagaca gttgggatct ctgcttccca
     2701 gtacagatat ggaccccaac tcagaagcat cagatatctc ctagtgtcct tatccaggag
     2761 gcctgcccct atgccaccct tccttttcac actgtgatgc cttccctggc agtcaggctg
     2821 ggtatcacag gcccagaggg cttgtatggg ggcagagaca ggaaagtcct gcaaggtcat
     2881 ctgtccaact gagttctcgg gagcagggca cctcagtgct gccctgtccc caagatcaca
     2941 ctcccaggca ttggcagcct gtgtgtccct ctcccaccct gctgcctggc accctgagcc
     3001 atgccttcct gaggcctgcc tgggcaggtt taaggtgatg ctgtgcctgc cgccgtgggc
     3061 acagaaatgt tgacgcttgc ccagctctgg gctgccctga tgctcctctc ttccttgctt
     3121 tccctcccga gtccacgctc agccaacaga ttagcaaaga agccatgggg aaagcattgc
     3181 ccgcaagtac agcatggtga tcacgtcatg atttcccata gccccagagt gcaggtactg
     3241 ttcctcacca gcctccatca gtcgtcatgg aggtcgtcag acgtccaggg acacaaccca
     3301 aagccccttc gtgggatcat cctctctcca taggagagtc gtggctgggt ccaagctctc
     3361 ttagccatct gacctacctg cagccatctt cctttctggc ctaccagatg ccaacaggag
     3421 aattcaacac cttcatgtca ccagggggaa ctgtgtaccc ctgtacctat ttggggtagt
     3481 ttgcacagtg ccaaaccttc taactaagtc atcatccaaa cccaggatgt cagtgttgcc
     3541 atattccaca cagattgatt ggcaagccaa actgggaccc tgccacccca ccctcttctc
     3601 caaagcattt tcaaatgagt ctttgattta gcacaacaaa attgaaacct gctccttaca
     3661 tctcgccctc cagtcatcga ggatggctga gccacttgtt tggtgcctta gcaagtagct
     3721 ggctgacacc cttgtgtaag acatctgctg cttcctgtca tctgccagat cgttgattcc
     3781 atcaaaatat caggcagcct tatttgtttt taacacagag tattctgttc ttgctcagtt
     3841 gactagagat gtcttctgct tcccccaccc catagggatt ccgtgtcctg gcctggtact
     3901 tattatatag cccagcctgc acttggactc acagtcattc tcctgcctca gcctctcaag
     3961 tattgggatt acaagcttga accataaaac tttctttttt tagatttatt tttacttatg
     4021 tgtacttgtt tgtgggttat gtgtacatga gtgaaggtgc ccagagacca gaagagggtg
     4081 tcagagtccc ttaaagctgg agttacagga ggttgtaagc caccatgtgt ggggctgaga
     4141 gctgagctca aatcctctgg gagagcagta agtgctgagc caattgctcc ggaacccctt
     4201 ccccataact gttttgaaga aaagattaga agtaaggcaa gctagatgtg gcacacaccg
     4261 gtgtcctagc attagggtgg ccagggcagg agaactgagg tttaaagcta gcctgggcta
     4321 catggagagt cccagtatgg gcaacttaaa aagatcctct ctcaaagaaa ctttaaaagg
     4381 acaaaaataa ctgggcatgg tggtatatgc cttaaatctt agcatgccca aagcatgggg
     4441 tggagaatct cttgtgaatt caagaccagc ctggttgact cagtaaattt caggccagct
     4501 agagttatat gagaccttct ctcaatcaat caatcaatca atcaatcttc tctcaatcag
     4561 tcagtcagta agcaggaata attatggtga agaaatggtt gaaataagtg agagacacaa
     4621 aaaggagtta tgtaacttct catgatcatc ccttgagggt gtagggaagg gctgaggagt
     4681 tttccccaca acactgcata cgatgtggca ccggtgaggg ggcagcagct gcttgaagct
     4741 gtgatgatag gaaaccacgg tggctctgct gggactgtgg gacaaggttc tttattcctc
     4801 tttggatcaa atttgtgttt atttttcgaa tgtgattata tgctactgaa ataaaaaata
     4861 catttatttt taaa
//
