LOCUS       NM_008239               2821 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Mus musculus forkhead box Q1 (Foxq1), mRNA.
ACCESSION   NM_008239
VERSION     NM_008239.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2821)
  AUTHORS   Luo,Z., Zeng,H., Yang,K. and Wang,Y.
  TITLE     FOXQ1 inhibits the progression of osteoarthritis by regulating
            pyroptosis
  JOURNAL   Aging (Albany NY) 16 (6), 5077-5090 (2024)
   PUBMED   38503493
  REMARK    GeneRIF: FOXQ1 inhibits the progression of osteoarthritis by
            regulating pyroptosis.
REFERENCE   2  (bases 1 to 2821)
  AUTHORS   Huang,X., Wu,J., Wang,Y., Xian,Z., Li,J., Qiu,N. and Li,H.
  TITLE     FOXQ1 inhibits breast cancer ferroptosis and progression via the
            circ_0000643/miR-153/SLC7A11 axis
  JOURNAL   Exp Cell Res 431 (1), 113737 (2023)
   PUBMED   37591453
  REMARK    GeneRIF: FOXQ1 inhibits breast cancer ferroptosis and progression
            via the circ_0000643/miR-153/SLC7A11 axis.
REFERENCE   3  (bases 1 to 2821)
  AUTHORS   Yang,Y., Ma,Y., Li,M., Zhu,H., Shi,P. and An,R.
  TITLE     STUB1 directs FOXQ1-mediated transactivation of Ldha gene and
            facilitates lactate production in mouse Sertoli cells
  JOURNAL   Cell Tissue Res 392 (2), 565-579 (2023)
   PUBMED   36575252
  REMARK    GeneRIF: STUB1 directs FOXQ1-mediated transactivation of Ldha gene
            and facilitates lactate production in mouse Sertoli cells.
REFERENCE   4  (bases 1 to 2821)
  AUTHORS   Allegre,N., Chauveau,S., Dennis,C., Renaud,Y., Meistermann,D.,
            Estrella,L.V., Pouchin,P., Cohen-Tannoudji,M., David,L. and
            Chazaud,C.
  TITLE     NANOG initiates epiblast fate through the coordination of
            pluripotency genes expression
  JOURNAL   Nat Commun 13 (1), 3550 (2022)
   PUBMED   35729116
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2821)
  AUTHORS   Liu,Z., Yuan,M., Meng,X., Bie,H. and Yao,S.
  TITLE     Identification of testicular Foxq1 as a critical modulator of
            lactate metabolism in mouse Sertoli cells
  JOURNAL   Histochem Cell Biol 156 (3), 227-237 (2021)
   PUBMED   34091745
  REMARK    GeneRIF: Identification of testicular Foxq1 as a critical modulator
            of lactate metabolism in mouse Sertoli cells.
REFERENCE   6  (bases 1 to 2821)
  AUTHORS   Dickinson,M.E., Kobrin,M.S., Silan,C.M., Kingsley,D.M.,
            Justice,M.J., Miller,D.A., Ceci,J.D., Lock,L.F., Lee,A.,
            Buchberg,A.M. et al.
  TITLE     Chromosomal localization of seven members of the murine TGF-beta
            superfamily suggests close linkage to several morphogenetic mutant
            loci
  JOURNAL   Genomics 6 (3), 505-520 (1990)
   PUBMED   1970330
REFERENCE   7  (bases 1 to 2821)
  AUTHORS   Justice,M.J., Silan,C.M., Ceci,J.D., Buchberg,A.M., Copeland,N.G.
            and Jenkins,N.A.
  TITLE     A molecular genetic linkage map of mouse chromosome 13 anchored by
            the beige (bg) and satin (sa) loci
  JOURNAL   Genomics 6 (2), 341-351 (1990)
   PUBMED   2307475
REFERENCE   8  (bases 1 to 2821)
  AUTHORS   Lane,P.W. and Murphy,E.D.
  TITLE     Susceptibility to spontaneous pneumonitis in an inbred strain of
            beige and satin mice
  JOURNAL   Genetics 72 (3), 451-460 (1972)
   PUBMED   4643821
REFERENCE   9  (bases 1 to 2821)
  AUTHORS   Green,M.C.
  TITLE     The developmental effects of congenital hydrocephalus (ch) in the
            mouse
  JOURNAL   Dev Biol 23 (4), 585-608 (1970)
   PUBMED   5500588
REFERENCE   10 (bases 1 to 2821)
  AUTHORS   Lyon,M.F. and Meredith,R.
  TITLE     Muted, a new mutant affecting coat colour and otoliths of the
            mouse, and its position in linkage group XIV
  JOURNAL   Genet Res 14 (2), 163-166 (1969)
   PUBMED   5367369
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147202.1, CJ056418.1, BQ032550.1 and BU755016.1.
            
            On Oct 6, 2007 this sequence version replaced NM_008239.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK147202.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-195               AK147202.1         7-201
            196-331             CJ056418.1         175-310
            332-2127            AK147202.1         338-2133
            2128-2301           BQ032550.1         13-186              c
            2302-2801           AK147202.1         2308-2807
            2802-2821           BU755016.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..2821
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 13.46 cM"
     gene            1..2821
                     /gene="Foxq1"
                     /gene_synonym="HFH-1; Hfh1; Hfh1l; sa"
                     /note="forkhead box Q1"
                     /db_xref="GeneID:15220"
                     /db_xref="MGI:MGI:1298228"
     exon            1..2807
                     /gene="Foxq1"
                     /gene_synonym="HFH-1; Hfh1; Hfh1l; sa"
                     /inference="alignment:Splign:2.1.0"
     CDS             748..1950
                     /gene="Foxq1"
                     /gene_synonym="HFH-1; Hfh1; Hfh1l; sa"
                     /note="HNF-3/forkhead homolog 1 like; HFH-1l;
                     HNF-3/forkhead-like protein 1; hepatocyte nuclear factor 3
                     forkhead homolog 1; satin"
                     /codon_start=1
                     /product="forkhead box protein Q1"
                     /protein_id="NP_032265.3"
                     /db_xref="CCDS:CCDS26423.1"
                     /db_xref="GeneID:15220"
                     /db_xref="MGI:MGI:1298228"
                     /translation="MKLEVFVPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDG
                     DCAANSPAAGSGAGDLEGGGGERNSSGGPSAQDGPEATDDSRTQASAAGPCAGGVGGG
                     EGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWR
                     NSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTV
                     SASGLRPEEAPPGPAGTPQPAPAARSSPIARSPARQEERSSPASKFSSSFAIDSILSK
                     PFRSRRDGDSALGVQLPWGAAPCPPLRAYPALLPAAPGGALLPLCAYGASEPTLLASR
                     GTEVQPAAPLLLAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLS
                     YPVETLLA"
     regulatory      2734..2739
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxq1"
                     /gene_synonym="HFH-1; Hfh1; Hfh1l; sa"
                     /note="hexamer: TATAAA"
     polyA_site      2753
                     /gene="Foxq1"
                     /gene_synonym="HFH-1; Hfh1; Hfh1l; sa"
     regulatory      2781..2786
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxq1"
                     /gene_synonym="HFH-1; Hfh1; Hfh1l; sa"
                     /note="hexamer: AATAAA"
     polyA_site      2807
                     /gene="Foxq1"
                     /gene_synonym="HFH-1; Hfh1; Hfh1l; sa"
                     /note="major polyA site"
ORIGIN      
        1 cgcgccgccg cgtggcctcg gcctgatgaa cgccttgggg ggagccgcgg ccacctcggc
       61 cacctagttc ccccaccccc tggccgtggg cgcccaggcc ccgcccgcgc ggagccgccg
      121 cagggttata ttgggccgga ccgaaggtgg aggcgagatt ctgctgcggc cggccagcgc
      181 ggacatgctg cccgggaagc cgggggtggc aaggcggctg cgggtgcggc ggcctcgaag
      241 actcctttct atgggctctc gaggctgaag acgtcctatc ctcaaaagta gcgggtgcgc
      301 cagcagacgt caggtcggtg cctgagacct agacatccag cgaaggaaca cttttggacg
      361 cccagaccga tagcataagc gccggctcgg tcctcccagc acgaaatcct aaggctggtg
      421 tgtcctggcc cccgcttcgc agggtggccc ctcattcctc gcttgtcttc cgctcaaagt
      481 ctctaaacct cggagtaagg acagcactgc accaacttct atcactccac tcctcacttc
      541 acccaacaat caaaacccct cccaaaaaaa atcccagcgg aggagaacct ttcggaaaag
      601 cgtctctctc ggaaagacgc aggagcggtc cctcccagga gaagacagac tcagcgggcc
      661 acgggatcgc cactccgggc gccactcgct tcctacgacc tcgcaggaaa ggggtaactg
      721 tgccggactg gaagcaccag cgccggcatg aaattggagg tgttcgtccc acgcgcagcc
      781 cacggggaca aaatgggcag cgatctggag ggggccggca gcagcgacgt gccatctcca
      841 ctgtccgcgg ctggtgacga ctccttaggc tcagacgggg actgtgcagc caacagcccg
      901 gcggcgggca gcggcgccgg ggatctggaa ggtggcggcg gcgagaggaa ttcgagtggc
      961 gggccgagcg cccaagacgg tccggaggca actgatgaca gcagaacgca ggcctccgcg
     1021 gcagggccgt gcgcgggcgg cgtgggcggc ggcgagggcg cgcgcagcaa gccgtacacg
     1081 cggcggccca agcccccata ctcctacatc gctctcatcg ccatggccat ccgcgactcc
     1141 gcgggcggac gcctgacact ggccgagatc aacgagtacc tcatgggcaa gttccccttt
     1201 ttccggggca gctacacggg ctggcgcaac tccgtgcgcc acaacctctc gctcaacgac
     1261 tgtttcgtca aggtgctgcg cgacccctcg cggccctggg gcaaggacaa ctactggatg
     1321 ctcaacccca acagcgaata caccttcgcc gacggggtct tccgccgccg ccgcaagcgc
     1381 ctcagccacc ggaccacagt ctccgcgtcc gggctgcggc cggaggaagc cccacccgga
     1441 cctgccggga ccccgcagcc cgcgcccgcc gcccgctcct ccccgatcgc gcgctcgccg
     1501 gctcgccagg aggagcgctc cagccctgcg agcaagttct ccagctcctt cgccatcgac
     1561 agcattctca gcaagccttt tcgcagccgc cgcgacggcg actcggctct gggggtgcag
     1621 ctaccctggg gcgccgctcc ctgcccgccg ctgcgcgcct atcccgcgct ccttcccgcg
     1681 gcgcccggtg gcgctctgct accgctctgt gcttacggcg caagcgagcc tacgctgctg
     1741 gcgtcgcgcg ggaccgaggt gcagcccgcg gcgccccttc tgctggcgcc cctctccacc
     1801 gcggctccag ccaagccatt ccgaggtccg gagaccgccg gcgcggcgca cctgtactgc
     1861 cccctacggc tgcccacggc cctgcaggcg gcagcggcct gcggtcccgg tccgcacctg
     1921 tcctacccgg tggagactct gctagcttga caggagctct gtgctcagca gaaggggtgc
     1981 tgagcagggt ggagttgggg gcgccttttg ttgaggaggt tggaatgtgg gctctagggc
     2041 tgtgcacttt ccactttccg gaggaataga gtttttcttt ttttcaactc tccatcaaat
     2101 gtgccttaaa gttaagcatt ttgacccaag tgttttaact tagtccagaa tagtttcctt
     2161 tgtcttttgt aactttacag aggatcaaag ccgttctttt ccatttcttg gccaggcctg
     2221 tactctcccg catagaggct ttcctttccc tcctatttgc gtcacgcctt ccactgattt
     2281 accttcccca cccataaaaa agaaaaagaa aaatacatca gggaaccact ccatggggta
     2341 aatgatgact actgtttggg gttttgagac cccgctgtgt aaatgtgtgt ctttcacagg
     2401 agtgactgct gcgtgtaaga gagctgtcaa tcaaacttat ggtcattttc tttgctaaca
     2461 accaatgctt cactgtgcca aaaaaaaaaa aaaagaggga aatgttgttg ggtttttgta
     2521 attaaattat ttatatattt ttgaaacctg aattgaaatg ttgcaggcaa cggctacagc
     2581 tttattagtg gttacctaac tgtggtcttc ttgggccaag caatttcttt aaaggaaaag
     2641 ttagcattat gtttgtgggg tgccagggcc gccaccacga gaaaccgtgt gatttttatt
     2701 ttaatattat ttgtgtctgt gtatatattt gtatataaat tttatgaacc ccaggcatac
     2761 tgcttgtttt tttaaaaaaa aataaaactc aaaattgatc tacaaaaaaa aaaaaaaaaa
     2821 a
//
