LOCUS       NM_012020               2520 bp    mRNA    linear   ROD 11-NOV-2023
DEFINITION  Mus musculus forkhead box L2 (Foxl2), mRNA.
ACCESSION   NM_012020 XM_976602
VERSION     NM_012020.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2520)
  AUTHORS   Xin Q, Yu G, Feng I and Dean J.
  TITLE     Chromatin remodeling of prostaglandin signaling in smooth muscle
            enables mouse embryo passage through the female reproductive tract
  JOURNAL   Dev Cell 58 (18), 1716-1732 (2023)
   PUBMED   37714160
REFERENCE   2  (bases 1 to 2520)
  AUTHORS   Schindler M, Osterwalder M, Harabula I, Wittler L, Tzika AC,
            Dechmann DKN, Vingron M, Visel A, Haas SA and Real FM.
  TITLE     Induction of kidney-related gene programs through co-option of
            SALL1 in mole ovotestes
  JOURNAL   Development 150 (17) (2023)
   PUBMED   37519269
REFERENCE   3  (bases 1 to 2520)
  AUTHORS   Xu W, Yang Y, Yu Y, Wen C, Zhao S, Cao L, Zhao S, Qin Y and Chen
            ZJ.
  TITLE     FAAP100 is required for the resolution of transcription-replication
            conflicts in primordial germ cells
  JOURNAL   BMC Biol 21 (1), 174 (2023)
   PUBMED   37580696
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2520)
  AUTHORS   Okashita N, Maeda R and Tachibana M.
  TITLE     CDYL reinforces male gonadal sex determination through
            epigenetically repressing Wnt4 transcription in mice
  JOURNAL   Proc Natl Acad Sci U S A 120 (20), e2221499120 (2023)
   PUBMED   37155872
REFERENCE   5  (bases 1 to 2520)
  AUTHORS   Gu X, Heinrich A, Li SY and DeFalco T.
  TITLE     Testicular macrophages are recruited during a narrow fetal time
            window and promote organ-specific developmental functions
  JOURNAL   Nat Commun 14 (1), 1439 (2023)
   PUBMED   36922518
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2520)
  AUTHORS   Ellsworth BS, Burns AT, Escudero KW, Duval DL, Nelson SE and Clay
            CM.
  TITLE     The gonadotropin releasing hormone (GnRH) receptor activating
            sequence (GRAS) is a composite regulatory element that interacts
            with multiple classes of transcription factors including Smads,
            AP-1 and a forkhead DNA binding protein
  JOURNAL   Mol Cell Endocrinol 206 (1-2), 93-111 (2003)
   PUBMED   12943993
REFERENCE   7  (bases 1 to 2520)
  AUTHORS   Loffler KA, Zarkower D and Koopman P.
  TITLE     Etiology of ovarian failure in blepharophimosis ptosis epicanthus
            inversus syndrome: FOXL2 is a conserved, early-acting gene in
            vertebrate ovarian development
  JOURNAL   Endocrinology 144 (7), 3237-3243 (2003)
   PUBMED   12810580
  REMARK    GeneRIF: FOXL2 is a highly conserved early regulator of vertebrate
            ovarian development.
REFERENCE   8  (bases 1 to 2520)
  AUTHORS   Cocquet,J., Pailhoux,E., Jaubert,F., Servel,N., Xia,X.,
            Pannetier,M., De Baere,E., Messiaen,L., Cotinot,C., Fellous,M. and
            Veitia,R.A.
  TITLE     Evolution and expression of FOXL2
  JOURNAL   J Med Genet 39 (12), 916-921 (2002)
   PUBMED   12471206
  REMARK    GeneRIF: Molecular evolution and expression of FOXL2
REFERENCE   9  (bases 1 to 2520)
  AUTHORS   Crisponi L, Deiana M, Loi A, Chiappe F, Uda M, Amati P, Bisceglia
            L, Zelante L, Nagaraja R, Porcu S, Ristaldi MS, Marzella R, Rocchi
            M, Nicolino M, Lienhardt-Roussie A, Nivelon A, Verloes A,
            Schlessinger D, Gasparini P, Bonneau D, Cao A and Pilia G.
  TITLE     The putative forkhead transcription factor FOXL2 is mutated in
            blepharophimosis/ptosis/epicanthus inversus syndrome
  JOURNAL   Nat Genet 27 (2), 159-166 (2001)
   PUBMED   11175783
REFERENCE   10 (bases 1 to 2520)
  AUTHORS   Kioussi C, O'Connell S, St-Onge L, Treier M, Gleiberman AS, Gruss P
            and Rosenfeld MG.
  TITLE     Pax6 is essential for establishing ventral-dorsal cell boundaries
            in pituitary gland development
  JOURNAL   Proc Natl Acad Sci U S A 96 (25), 14378-14382 (1999)
   PUBMED   10588713
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC137812.1 and AC120148.13.
            
            [WARNING] On Jan 11, 2024 this sequence was replaced by
            NM_012020.3.
            
            On Sep 3, 2009 this sequence version replaced NM_012020.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137811.1, SRR7652917.803266.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1241              BC137812.1         1-1241
            1242-2520           AC120148.13        100629-101907       c
FEATURES             Location/Qualifiers
     source          1..2520
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 51.41 cM"
     gene            1..2520
                     /gene="Foxl2"
                     /gene_synonym="BPES; Pfrk; PINTO"
                     /note="forkhead box L2"
                     /db_xref="GeneID:26927"
                     /db_xref="MGI:MGI:1349428"
     exon            1..2520
                     /gene="Foxl2"
                     /gene_synonym="BPES; Pfrk; PINTO"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1182
                     /gene="Foxl2"
                     /gene_synonym="BPES; Pfrk; PINTO"
                     /note="putative transcription factor foxl2; P-Frk;
                     pituitary forkhead factor"
                     /codon_start=1
                     /product="forkhead box protein L2"
                     /protein_id="NP_036150.1"
                     /db_xref="CCDS:CCDS23430.1"
                     /db_xref="GeneID:26927"
                     /db_xref="MGI:MGI:1349428"
                     /translation="MMASYPEPEDTAGTLLAPESGRAVKEAEASPPSPGKGGGTTPEK
                     PDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNL
                     SLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGK
                     GLFGSGGAAGGCGVPGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAA
                     AAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGP
                     PAAPPPPPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAP
                     APTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL"
ORIGIN      
        1 caccaggaga gcacagcctc cgggctgccc ggccgcggag agccggcttt tgtcatgatg
       61 gccagctacc ccgagcccga agacacggcg gggaccctgc tggctccgga gagcggacgc
      121 gcagtcaaag aggccgaggc gtcgccgccg agtcccggca agggaggcgg gacaacaccg
      181 gagaaaccag accccgcgca gaagcccccg tactcgtacg tggcgctcat cgccatggcg
      241 atccgcgaga gcgccgagaa gaggctcact ctgtccggca tctaccagta catcatagcc
      301 aagttcccgt tctacgagaa gaacaagaag ggctggcaga atagcatccg ccacaacctc
      361 agcctcaacg agtgcttcat caaggtgccg cgcgagggcg gcggcgagcg caagggcaac
      421 tactggacgc tcgacccggc ctgcgaggac atgttcgaga agggcaacta ccggcgccgc
      481 cgccgcatga agcggccctt ccggccgccg cccgctcact tccagcccgg caaggggctc
      541 ttcgggagcg gaggagcggc gggtggctgc ggcgtgcccg gagctggggc cgatggctat
      601 ggctacctgg cgccacccaa gtacctgcaa tcggggttcc tcaacaactc ctggcccctg
      661 ccgcagcctc cctcgcccat gccctacgcc tcctgccaga tggcggcggc tgcggcggcc
      721 gctgctgcag ccgctgcagc cgccggcccg ggcagccccg gtgcagccgc ggtggtcaag
      781 gggctggcgg gccccgccgc ctcctacggg ccgtactcgc gcgtgcagag catggcgctg
      841 cctccgggcg tcgtgaactc ctacaacggc ctggggggcc ctcctgccgc accaccgccg
      901 ccgccaccgc cgccgcaccc tcacccgcac cctcacgcac atcatctgca cgcggccgct
      961 gcgcccccgc cagccccgcc acaccacggg gctgccgcgc ctcccccggg tcagctcagt
     1021 cccgccagcc cggccaccgc cgcgcccccg gcacccgcgc ccacgagcgc gcccggcctg
     1081 cagttcgcct gcgcccggca acccgagctc gccatgatgc attgctcata ctgggaccac
     1141 gacagcaaga cgggcgcgct gcactcgcgt ctggatctct gagtgccaac gcgcgcggga
     1201 gcggtccccc acccctatcc cgggagtgga ggagccgagc tcgggtcgca gccgcagcag
     1261 ccagcctgac agcgcgcact ccgggacagc ttctggatgc agagccctcg agcggtctgc
     1321 ccttcctcgg tccgccccgc tcctgcgact ccgctttgtc gcctccgctg ctcctccggt
     1381 gctcttcccc gccgcggcct ctgctttccc gtgctgctgg ccggaggccg cccactccgt
     1441 gctttccgcg ggcctcctct cctcaccgca gggagtgagt ccccggccga ggtgcggtcg
     1501 aagtgtctga gacgcagctt acctcttggc cctctcttcc aggtcggtgg actcaagctc
     1561 gattttattt ttaattcccc accccgactg tctgcgacta gaagcgctag gctgctgggg
     1621 gaagagggac ccacactacc ggagaatgga aagaacgtgt ctggtcgctc tgcgatccct
     1681 cctggaactg atcagaagcc gcttgcagag gggcccactg ggcggggcgg gggttgagcc
     1741 ccaggctgga gcagggacag cctcgttccg cggcctgcaa ccgagttctc atcccccgct
     1801 ccttgtgagg ccgtggtgcc tccgctccgc agagcaccgc atagggcacc tccaggccag
     1861 gtctttatga aaaagattgg tgaggctttt gaaaatatta aaaaatactt tttaaagaaa
     1921 aaaagaaaga gggagagaat aaaacattca tgggggggtg gggaggagaa atgtaatggc
     1981 cttggagttt gctaaaacca aacaacaaaa tcaaaagttt tggttttctt catcgaccct
     2041 gctgggaaat ttgtgtaaga attcccgtgg tgacttcatt aggctgtgtt cagagggagg
     2101 agaaaataac tagctaaaat aaggtttcca ctacaaatta ggaatttctt ttctatttaa
     2161 aagttgaact caaaacaaat ttccccggat cttccgattc tgccccggat gccagaagag
     2221 atctctgcct ggctggtaca caccgcccag atgacactcc tatccctgat ttttgttttt
     2281 ccaatgtctt gtttcttcca ccttcggaag gagaaatgtg aaactcgtca tggccggccc
     2341 acacgggctt gtggccccag ccggctggcc cgaaatcccg tgacctggtg gttgagtaat
     2401 gtctttcggg gaccaaattt tctagaggga actagagcac ttttgttgtg tttgtacgtg
     2461 tgtgagggcg tcccttgtca attcccaaat aaattttttt gttttttgtt tttcttttaa
//
