LOCUS       NM_008024               2812 bp    mRNA    linear   ROD 21-AUG-2024
DEFINITION  Mus musculus forkhead box L1 (Foxl1), mRNA.
ACCESSION   NM_008024
VERSION     NM_008024.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2812)
  AUTHORS   Yoshida,S., Tsuneoka,Y., Tsukada,T., Nakakura,T., Kawamura,A.,
            Kai,W. and Yoshida,K.
  TITLE     Primary Cilia are Required for Cell-Type Determination and
            Angiogenesis in Pituitary Development
  JOURNAL   Endocrinology 165 (8) (2024)
   PUBMED   39001875
REFERENCE   2  (bases 1 to 2812)
  AUTHORS   Kraiczy,J., McCarthy,N., Malagola,E., Tie,G., Madha,S.,
            Boffelli,D., Wagner,D.E., Wang,T.C. and Shivdasani,R.A.
  TITLE     Graded BMP signaling within intestinal crypt architecture directs
            self-organization of the Wnt-secreting stem cell niche
  JOURNAL   Cell Stem Cell 30 (4), 433-449 (2023)
   PUBMED   37028407
REFERENCE   3  (bases 1 to 2812)
  AUTHORS   Yogosawa,S., Ohkido,M., Horii,T., Okazaki,Y., Nakayama,J.,
            Yoshida,S., Toyokuni,S., Hatada,I., Morimoto,M. and Yoshida,K.
  TITLE     Mice lacking DYRK2 exhibit congenital malformations with lung
            hypoplasia and altered Foxf1 expression gradient
  JOURNAL   Commun Biol 4 (1), 1204 (2021)
   PUBMED   34671097
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2812)
  AUTHORS   Kondo,A. and Kaestner,K.H.
  TITLE     FoxL1+ mesenchymal cells are a critical source of Wnt5a for midgut
            elongation during mouse embryonic intestinal development
  JOURNAL   Cells Dev 165, 203662 (2021)
   PUBMED   33993983
REFERENCE   5  (bases 1 to 2812)
  AUTHORS   Kolev,H.M., Tian,Y., Kim,M.S., Leu,N.A., Adams-Tzivelekidis,S.,
            Lengner,C.J., Li,N. and Kaestner,K.H.
  TITLE     A FoxL1-CreERT-2A-tdTomato Mouse Labels Subepithelial Telocytes
  JOURNAL   Cell Mol Gastroenterol Hepatol 12 (3), 1155-1158 (2021)
   PUBMED   34029742
REFERENCE   6  (bases 1 to 2812)
  AUTHORS   Jensen,J., Pedersen,E.E., Galante,P., Hald,J., Heller,R.S.,
            Ishibashi,M., Kageyama,R., Guillemot,F., Serup,P. and Madsen,O.D.
  TITLE     Control of endodermal endocrine development by Hes-1
  JOURNAL   Nat Genet 24 (1), 36-44 (2000)
   PUBMED   10615124
REFERENCE   7  (bases 1 to 2812)
  AUTHORS   Kaestner,K.H., Silberg,D.G., Traber,P.G. and Schutz,G.
  TITLE     The mesenchymal winged helix transcription factor Fkh6 is required
            for the control of gastrointestinal proliferation and
            differentiation
  JOURNAL   Genes Dev 11 (12), 1583-1595 (1997)
   PUBMED   9203584
REFERENCE   8  (bases 1 to 2812)
  AUTHORS   Kaestner,K.H., Bleckmann,S.C., Monaghan,A.P., Schlondorff,J.,
            Mincheva,A., Lichter,P. and Schutz,G.
  TITLE     Clustered arrangement of winged helix genes fkh-6 and MFH-1:
            possible implications for mesoderm development
  JOURNAL   Development 122 (6), 1751-1758 (1996)
   PUBMED   8674414
REFERENCE   9  (bases 1 to 2812)
  AUTHORS   Pierrou,S., Hellqvist,M., Samuelsson,L., Enerback,S. and
            Carlsson,P.
  TITLE     Cloning and characterization of seven human forkhead proteins:
            binding site specificity and DNA bending
  JOURNAL   EMBO J 13 (20), 5002-5012 (1994)
   PUBMED   7957066
REFERENCE   10 (bases 1 to 2812)
  AUTHORS   Kaestner,K.H., Lee,K.H., Schlondorff,J., Hiemisch,H., Monaghan,A.P.
            and Schutz,G.
  TITLE     Six members of the mouse forkhead gene family are developmentally
            regulated
  JOURNAL   Proc Natl Acad Sci U S A 90 (16), 7628-7631 (1993)
   PUBMED   7689224
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127554.4.
            
            On Feb 1, 2022 this sequence version replaced NM_008024.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC137806.1, AB221616.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2812              AC127554.4         51416-54227
FEATURES             Location/Qualifiers
     source          1..2812
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 70.34 cM"
     gene            1..2812
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="forkhead box L1"
                     /db_xref="GeneID:14241"
                     /db_xref="MGI:MGI:1347469"
     exon            1..2812
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1739..1744
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="hexamer: GATAAA"
     polyA_site      1758
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="major polyA site"
     regulatory      2042..2047
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="hexamer: ATTAAA"
     polyA_site      2061
                     /gene="Foxl1"
                     /gene_synonym="fkh-6; Fkh6; FREAC7"
                     /note="major polyA site"
ORIGIN      
        1 gacaaagcgc gcagcggctg gggagagcgg ctgatcgcag ggcagtcgca cagagggctc
       61 cccaggaggg ccctggtgcg gggcaaagtc cttaggactc cccggtggag cggagaggct
      121 gctgtcgcca tgagccacct cttcagtccc ccgctggccg ctctggcagc ctcgccgctg
      181 ttgtacgtgt acagccccga gaggcctggg ctgcccctgg ccttcgcccc tgcggctgca
      241 ctggccggcc cgggccgcgt cgagcccccg cagaagccgc cctacagcta catcgctctt
      301 atagccatgg cgatccagga tgctcccgag cagagggtca cactgaacgg catctaccag
      361 ttcatcatgg atcgcttccc gttctaccac gacaaccgcc aaggctggca gaacagcatc
      421 cgccacaacc tgtcgctcaa cgagtgcttc gtgaaggtgc cacgtgagaa ggggcggccg
      481 ggcaagggca gctactggac cctggacccc cgctgcttgg acatgtttga gaacggcaat
      541 tatcggcgca ggaagaggaa gcccaagccc gccgcgggtt ccccggaggc caagcgcacc
      601 cgggtcgagc cgccggagtc cgaggtgggc tgcgatgtag ggtccccgga cctggccact
      661 gcactcccga cgcgcgcgcc ggatcgctcc caatccccgg cagtaggcac cgcgcggccc
      721 gcgctccttc cctggcccgg ccctgagccc cgggaccccg acgcggacct cacagtccag
      781 ggcgcagggg cagtggcaag cggccagctc cagcgtccgg cacaccacct ggggtcccct
      841 ctgtgccccg cccccagcgg ctccccaaaa ggttccaagt caaagagttt cagcatcgac
      901 agcatcttgg ccgtgagacc gacgccagcc tcaggggccg aagcaccggg gatccctaag
      961 cccgtgcctg gcgcgctggg ctcctctctg ctggctgcct cctccggcct agcgcctccc
     1021 ttcaacgctt cgctggtctt cgacgcgcac gtccagggcg gcttttccca gctggggatt
     1081 cccttccttt cttattttcc tctgcaggtt cccgaggcca cagtgcttcg tttccactaa
     1141 ggcggattag cggctgcttc cctgcctcgc gatcccccca cctccagtga gccaatgcct
     1201 gtgggcgaag gagtcgcccc ggtctctgcc ctggcagaga ctgagggttt ggagcagcgt
     1261 acccgtgccg gccaaagtcg tgcactgagg ggcctcgtcc atctgctttc tccgaagatg
     1321 acttaaccag ccaccggaag ctttgcagat ttaaaagact ggtccagtag aggacatggt
     1381 cgccgcacac tcagccctca cggttcgtct ccagcagaag cccctcgtag gctttggcgg
     1441 cgttgtacag tgaccaccac aagtccccac tcggacctga gtctcctgct gaccctgagg
     1501 gcaggactta gagatatagc gaacagctct atgtggaggt tcaactggat catggaaggc
     1561 tcagcgggct ccgtgtggca taggccttgg ctttgatctc attggatgtg gggagcttgc
     1621 agccaggatg ctggggatga tccgtggtcc gcaggctctg ggaaagatgt aggcctggtt
     1681 aacgtttaca actaaggttg aacaaaagca ggctcaccgg aaatgctcaa tatgaataga
     1741 taaaccttct tccagacagg gaaaggctca tttattcttg gcttataaac caggctcccc
     1801 tttgctatag ctagtagctt cttttaagga gccccgtgtg tttggcacgt actttggctt
     1861 tacagtggca cacctgccgc attccacagc atagtcctct gttcacttct gcttttcttt
     1921 tctttttttt tttttgtgtg ggggggaggg gttcgagaca gggtttctct gtatagccct
     1981 ggctgtcctg gaactcactt tgtagaccag gctggcctgc ctctgcctcc cgagagctgg
     2041 gattaaaggc gtactccacc atgcctggcc tgcttttctt tttaaggcac caaaaaattt
     2101 caggggacac agaagggtgt gtgatcggag ggattattat gactcaaggg cgggtttttt
     2161 ttttaacttc tgtagctttt taagatctaa gtcccccccc catctctctc ccccccccca
     2221 ctcacacttt ccagaaacac acacacagtg aaggactaca tgtaatcaga gaggctgggg
     2281 gagcatacta ctcctgagtg tgggagatag atagcttcca ggagtgacag ggactctctt
     2341 cagacaaagc ctgtggtacc tcaagtctgt gttcccttta tatccctcca gggagatcta
     2401 gatattgaca ttacataaac ccataagagg tgaccagaga gcggggttga gggggagggg
     2461 gtggggagat caacaaagtg ctgactaagg caactaagtt ggttaccgtg cagtgcagtc
     2521 ctgcttccaa atttggggga aactctcagg cctttggggt gcccatgttt aagcttgctg
     2581 gtgggctctg caactcagct ttcagaggaa ggaaagtgct ggtccttgat gtaaaaaaaa
     2641 ggaccaaaaa ttaagaattc tagggcatag gtccacagtg atgtctcaca acaactaagg
     2701 tatgccgtgc atcacacctg taatctcagt ccttgcaagg ctgaggcagg gggattgctg
     2761 tgagtttaag gatagcttgt ggcacagagt tagacatgtc tcaaactaag gg
//
