LOCUS       NM_021899               5013 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus forkhead box J2 (Foxj2), mRNA.
ACCESSION   NM_021899
VERSION     NM_021899.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5013)
  AUTHORS   Bai,F.R., Wu,Q.Q., Wu,Y.J., Hu,Y.Q., Jiang,Z.X., Lv,H., Qian,W.Z.,
            Cai,C. and Wu,J.W.
  TITLE     Germline FOXJ2 overexpression causes male infertility via aberrant
            autophagy activation by LAMP2A upregulation
  JOURNAL   Cell Death Dis 13 (7), 665 (2022)
   PUBMED   35908066
  REMARK    GeneRIF: Germline FOXJ2 overexpression causes male infertility via
            aberrant autophagy activation by LAMP2A upregulation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5013)
  AUTHORS   Memic,F., Knoflach,V., Morarach,K., Sadler,R., Laranjeira,C.,
            Hjerling-Leffler,J., Sundstrom,E., Pachnis,V. and Marklund,U.
  TITLE     Transcription and Signaling Regulators in Developing Neuronal
            Subtypes of Mouse and Human Enteric Nervous System
  JOURNAL   Gastroenterology 154 (3), 624-636 (2018)
   PUBMED   29031500
REFERENCE   3  (bases 1 to 5013)
  AUTHORS   Ni,L., Xie,H. and Tan,L.
  TITLE     Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3
            conditional knockout mouse models
  JOURNAL   Mol Reprod Dev 83 (12), 1060-1069 (2016)
   PUBMED   27739607
REFERENCE   4  (bases 1 to 5013)
  AUTHORS   Miao,H., Miao,C.X., Li,N. and Han,J.
  TITLE     FOXJ2 controls meiosis during spermatogenesis in male mice
  JOURNAL   Mol Reprod Dev 83 (8), 684-691 (2016)
   PUBMED   27316861
  REMARK    GeneRIF: FOXJ2 appears to promote meiotic progression in male mice
            by a mechanism that needs further investigation.
REFERENCE   5  (bases 1 to 5013)
  AUTHORS   Liao,X., Li,S., Settlage,R.E., Sun,S., Ren,J., Reihl,A.M.,
            Zhang,H., Karyala,S.V., Reilly,C.M., Ahmed,S.A. and Luo,X.M.
  TITLE     Cutting Edge: Plasmacytoid Dendritic Cells in Late-Stage Lupus Mice
            Defective in Producing IFN-alpha
  JOURNAL   J Immunol 195 (10), 4578-4582 (2015)
   PUBMED   26447229
  REMARK    GeneRIF: Foxj2 seems to be required for the production of
            interferon-alpha in Plasmacytoid dendritic cells, because
            Foxj2-specific siRNA decreased interferon-alpha levels for both
            MRL/Mp-Fas-lpr, as well as its parent strain, MRL mice.
REFERENCE   6  (bases 1 to 5013)
  AUTHORS   Martin-de-Lara,F., Sanchez-Aparicio,P., Arias de la Fuente,C. and
            Rey-Campos,J.
  TITLE     Biological effects of FoxJ2 over-expression
  JOURNAL   Transgenic Res 17 (6), 1131-1141 (2008)
   PUBMED   18726704
  REMARK    GeneRIF: Biological effects of Foxj2 overexpression during
            development are reported.
REFERENCE   7  (bases 1 to 5013)
  AUTHORS   Wijchers,P.J., Hoekman,M.F., Burbach,J.P. and Smidt,M.P.
  TITLE     Identification of forkhead transcription factors in cortical and
            dopaminergic areas of the adult murine brain
  JOURNAL   Brain Res 1068 (1), 23-33 (2006)
   PUBMED   16376864
REFERENCE   8  (bases 1 to 5013)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   9  (bases 1 to 5013)
  AUTHORS   Granadino,B., Arias-de-la-Fuente,C., Perez-Sanchez,C., Parraga,M.,
            Lopez-Fernandez,L.A., del Mazo,J. and Rey-Campos,J.
  TITLE     Fhx (Foxj2) expression is activated during spermatogenesis and very
            early in embryonic development
  JOURNAL   Mech Dev 97 (1-2), 157-160 (2000)
   PUBMED   11025217
REFERENCE   10 (bases 1 to 5013)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163108.5.
            
            On Dec 18, 2009 this sequence version replaced NM_021899.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF253052.1, SRR10223971.7205.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-787               AC163108.5         45560-46346         c
            788-1134            AC163108.5         38027-38373         c
            1135-1209           AC163108.5         35020-35094         c
            1210-1278           AC163108.5         33524-33592         c
            1279-1419           AC163108.5         33229-33369         c
            1420-1615           AC163108.5         32654-32849         c
            1616-1999           AC163108.5         28326-28709         c
            2000-2101           AC163108.5         27845-27946         c
            2102-2311           AC163108.5         26860-27069         c
            2312-2410           AC163108.5         26206-26304         c
            2411-5013           AC163108.5         21164-23766         c
FEATURES             Location/Qualifiers
     source          1..5013
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 57.91 cM"
     gene            1..5013
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /note="forkhead box J2"
                     /db_xref="GeneID:60611"
                     /db_xref="MGI:MGI:1926805"
     exon            1..787
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            788..1134
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1209
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1278
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1419
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1615
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1999
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2101
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            2102..2311
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2410
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..5013
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4989..4994
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /note="hexamer: AATAAA"
     polyA_site      5010
                     /gene="Foxj2"
                     /gene_synonym="Fhx"
                     /note="major polyA site"
ORIGIN      
        1 ctgtgccggg acctgctccc tctcccttgg gagggaggac cctccctact ccccggacag
       61 ccagaagaga tcgccgcagg gcacgcggct gtccctccca cggtggctcc agcggagacc
      121 cccagaagtc gggaagggta gtgagacctg aaggacccgg agtgagacct ccctcacgcc
      181 tcagcgcact ccagacagtt tgggactttt gaggcagaga gaaagggagc catgcctgtg
      241 gagtaggcac cccgcatccc acccgggact caccgcggag aggcgtcctg atacgcacaa
      301 gccaggaccc tccagggaac cgccaggaat tggttccagt ttgctggaga gtagaagacc
      361 tcgcccctca acttccgtgc acctagacag tggaccgggg cagagcccct ccactcagat
      421 ctccaactga cagaaagagc cctcagcccc tgaaagatcc agtttggggg gggaggggga
      481 ttcccccaaa ggggaggaga caactcctgg ctgggagagg ctcctcccct cctccctagg
      541 gtagcaggca gggggtgggg ggtgtgccat cttccccagg taggtcctcc ctctccccct
      601 cctcctcctt cgactcctct tcctcagggg actcagttcc ctgctccagc ctgggaggct
      661 ccgccaggca ctggaagagt cactgaggat gccacctgtc acctgcctct gaagagggga
      721 atccctgcaa cctcaaactt ctgtaccagg tggtttcctc cagcggcggg gggagccttg
      781 gagacagaac ccagaagtac gatggcctcc gacctggaga gtagcctcac ctccatagac
      841 tggctgccac agctgactct cagagccact attgagaagc ttgggagcgc ttctcaggct
      901 gggcctccag ggggcgcccg gaagtgctcc ccaggctcgc ccacagatcc caacgccacc
      961 ctcagcaaag atgaggcagc ggtccaccaa gatggcaagc cacggtacag ctatgccacc
     1021 ctcatcacct acgccatcaa ctcctcccca gctaagaaga tgactctcag tgagatttac
     1081 cgctggatct gcgacaactt cccctattac aagaacgctg gcatcggttg gaagaattcc
     1141 attcgacaca acctttccct taacaagtgt ttccggaagg tgcccagacc tcgggatgac
     1201 cctgggaagg gctcctattg gacaattgac acctgccctg acatttcccg gaagagaaga
     1261 caccctccag atgatgacct atcccaagac tccccagagc aggaagccag caaaagcccc
     1321 cggggaggtg ttccagggag tggagaagcc tcactctctc acgaggggac tcctcagatg
     1381 tcacttcaga gcccctcctc cgtggccaac tacagccagg gcccagggtc tgtggatggt
     1441 ggagcagtgg cagcaggggc cccaggccag gagagcacag agggcgcccc tcccctctac
     1501 aacaccaacc atgacttcaa attctcctac tcagagatca actttcagga cctaagctgg
     1561 tccttccgca acctctacaa gtccatgctg gagcggtcct cctcctccca gcacggcttt
     1621 tcctcactcc tgggagacat gccaccttct aacaactact acgtgtacca gcagcagcaa
     1681 cagcagcagc caccaccaca gccacagcca ccaccccagc aaccacaacc acagcagcag
     1741 caggcaccca ctcagggccc ctcaaatgta gggggtgccc ctccactgca caccccaagc
     1801 cctgatggct gtactacacc agggggaaaa caagcgggcg ctgaaggcta cggccccccg
     1861 actgggatgg ccatgcatcc tcccccactg cagcacggag gctaccaccc tcatcagcac
     1921 catccccact cccaccctgc ccagcagcca ccacagccac aggcgcagag ccaggcatcc
     1981 atcaacagca ctggctttgc ctttcctcct gactggtgct ccaatattga ctccttaaag
     2041 gaaagcttca aaatggtgaa ccggctcaac tggtccagca tcgagcagtc ccagttctca
     2101 gagctcatgg agagcctacg gcaggcagag cagaggaact ggaccctcga ccagcatcac
     2161 atcgccaact tgtgtgactc cctcaaccac ttcctcaccc agactggtca catgccccaa
     2221 caagggggct cccaccgacc acctgcccct tcccgcatca ctgactcctg tgccctcacc
     2281 agtggcaaac cggagccatc catgaaccaa gtgaactctt acgggcaccc acaagcttcc
     2341 catctctacc ctggcccagc accaatgtac ccgatctcca cccaagactc agcaggatac
     2401 aaccgcccag cacaccacat ggttccccgg ccacctgtcc cacctcctgg tgccaatgag
     2461 gagatcaccg atgacttcga ctgggacttg atcacttaat gaatcacagt tgacatcagc
     2521 ccaaggcctg gtggtgaatt ctggccacgg gggaagagca gtccccggct atcctcccca
     2581 aacctgtata tagatatata gcttctttct gttctctctg tcagagacgc caccgcaaga
     2641 tgctgccgag gataatcctc ttttcctcct catcctttgt ttccctccta gttcattatt
     2701 attctaatta tattattatt attattattg gttacatact gcccagtctg ctgccctctt
     2761 accctgggct ttgccctccc tttgcccgtt tgaaatcttc aggtctcaag atgaggccgt
     2821 gatagctgtc aggaaaggct tcgaatgcta gttcaccttt ctctctgaga aactcagtgc
     2881 tgatcccacc tttcagctct gaactgtgtt ctgttcctgt ctgtttcagg ctggcctgga
     2941 gaggccacag taagtagagg ggaggctaag acactgcttg gcaaccatga cgttgcagtt
     3001 ttactcaatg gtgctaattg tgtcctctgc actctcccat tatacatccg atctttactt
     3061 tttccggcag tcctcatgcc catgatgggt ggacttggag agctgggttc cgtagagcgc
     3121 catggagcag tgatgggtat aacccagcat gaggttgggt atgcactgcc atatcaaaac
     3181 atccctggct tcttcctggt tgatgctctg gggaggttag cttgtccgct cgggcatgaa
     3241 gaccactgtg catcctaggt tcaacttctt ggaaacaatt tcaatttaag gcattttggc
     3301 tttggaaaag gaattctttc tgagagttag ctggctattc tgcatatata aatgaccttc
     3361 catcatctct tctccttcag catatacttt tttgtcttcc taaagctgtt tgtccaaatc
     3421 atctacctgt tttatttttt gttctcccat tttctgggaa tctcaaaaga caaaaggaag
     3481 ccattctcac tcctagtttc ttcatgtcat agacatgctg tggaaacctc tttccctcct
     3541 gtcacagcag actcatacct gtgatactgc tgacgggagg ttggggagaa gagagggaac
     3601 tggcggagat gtgggtggga acctgtcatt tgtttaactg cacagggaga cgcttctctt
     3661 gaagtccctg tcggtggggt ggaagctttt gattttgaca ggcaatgaat aattacattc
     3721 ccctgtaaga gggagatgaa ttatacagag acagggcgca gcaagggcaa ggcgcactcc
     3781 taggcacaga gtggggagtc tccattatca atgaacggcc atgatttatt gctgcagagg
     3841 tcttagtgag ggtgtggttg aattcgattc gagagaggga aatctcactt ccaccttatt
     3901 ttcactaaat tttctgaaac agacaaaatg tgtagtgttg acagggccaa tctccgtgac
     3961 ttttgttcat atgcttttat ttatccatga tttccaagac actgggcttc ccattctcac
     4021 ttcccctcat caatcccttt cctttcttta gaagggggct tatgtatgag actggtgaag
     4081 tccagtgaag ctaagtaaag gggcaagatg gggcagttca ctaaagagca ctttatttct
     4141 ttgtaaggaa aaaaaaaggg agtataagaa aaagtttcct ccagcagtgt gcgatgtact
     4201 ggagagcatc tggtgggcca gtgtatgaag cagtagttcc cgctagggaa cggggtgttt
     4261 ccctagagga ggcacacacc tttgccaggt gccctactag acatctcttg ctatgcctcc
     4321 catccaggtg tagtctccac agcttccctt tggtttcctc gaggtctctc ccttgcagat
     4381 taccacctct tcttctaagc acctttcctg gtcagatctg tccgcggttg gggagctagg
     4441 ctgagtcata ctcccaggtg ccccggcttc tccatgtctt gagaaccagt ctccctggtg
     4501 ggcagccaga gcagctacag tgggctggag actggagggt ggctttaggc cccctgaggt
     4561 tctagctctc cagggtcagg cttgcagaac ggggcagttt aaacctgatc ccctctgggc
     4621 ctccgattcc catgccctcc atgacgtgga aagggaacta cttttatttt gttggtccgg
     4681 tattgctgga catgaagtac agtccttgct gttgtcttgg gtgatatttg cacagttgtg
     4741 ggggtcactg cctataagag gaaatagggg agacagcaga ggtgcaggac aaaggagaag
     4801 tcatttgtgt tgctccacct atcctaggct tcctctcctc aaccccatgt ttctggtttg
     4861 gtgagttctt tataccaccc ataatgcttt gcattggtgc aggctgggaa gggggtgtat
     4921 gggctcacaa cttgtttggt ttttttgttt tgttttgttt ttgtttttgt ttttttgcat
     4981 gctttcttaa taaaaaaaaa gaaaagaaaa gaa
//
