LOCUS       NM_001101464            1206 bp    mRNA    linear   ROD 05-DEC-2024
DEFINITION  Mus musculus forkhead box I3 (Foxi3), mRNA.
ACCESSION   NM_001101464 XM_001477757 XM_144880
VERSION     NM_001101464.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1206)
  AUTHORS   Xing,X.L., Zeng,Z., Wang,Y., Pan,B. and Huang,X.
  TITLE     Identification of potential molecular mechanism related to
            craniofacial dysmorphism caused by FOXI3 deficiency
  JOURNAL   Mol Genet Genomic Med 12 (3), e2411 (2024)
   PUBMED   38433559
  REMARK    GeneRIF: Identification of potential molecular mechanism related to
            craniofacial dysmorphism caused by FOXI3 deficiency.
REFERENCE   2  (bases 1 to 1206)
  AUTHORS   Raymundo,J.R., Zhang,H., Smaldone,G., Zhu,W., Daly,K.E.,
            Glennon,B.J., Pecoraro,G., Salvatore,M., Devine,W.A., Lo,C.W.,
            Vitagliano,L. and Marneros,A.G.
  TITLE     KCTD1/KCTD15 complexes control ectodermal and neural crest cell
            functions, and their impairment causes aplasia cutis
  JOURNAL   J Clin Invest 134 (4), e174138 (2023)
   PUBMED   38113115
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1206)
  AUTHORS   Ankamreddy,H., Thawani,A., Birol,O., Zhang,H. and Groves,A.K.
  TITLE     Foxi3GFP and Foxi3CreER mice allow identification and lineage
            labeling of pharyngeal arch ectoderm and endoderm, and tooth and
            hair placodes
  JOURNAL   Dev Dyn 252 (12), 1462-1470 (2023)
   PUBMED   37543988
REFERENCE   4  (bases 1 to 1206)
  AUTHORS   Thawani,A., Maunsell,H.R., Zhang,H., Ankamreddy,H. and Groves,A.K.
  TITLE     The Foxi3 transcription factor is necessary for the fate
            restriction of placodal lineages at the neural plate border
  JOURNAL   Development 150 (19) (2023)
   PUBMED   37756587
  REMARK    GeneRIF: The Foxi3 transcription factor is necessary for the fate
            restriction of placodal lineages at the neural plate border.
REFERENCE   5  (bases 1 to 1206)
  AUTHORS   Christensen,M.M., Hallikas,O., Das Roy,R., Vaananen,V.,
            Stenberg,O.E., Hakkinen,T.J., Francois,J.C., Asher,R.J.,
            Klein,O.D., Holzenberger,M. and Jernvall,J.
  TITLE     The developmental basis for scaling of mammalian tooth size
  JOURNAL   Proc Natl Acad Sci U S A 120 (25), e2300374120 (2023)
   PUBMED   37307487
REFERENCE   6  (bases 1 to 1206)
  AUTHORS   Shirokova,V., Jussila,M., Hytonen,M.K., Perala,N., Drogemuller,C.,
            Leeb,T., Lohi,H., Sainio,K., Thesleff,I. and Mikkola,M.L.
  TITLE     Expression of Foxi3 is regulated by ectodysplasin in skin appendage
            placodes
  JOURNAL   Dev Dyn 242 (6), 593-603 (2013)
   PUBMED   23441037
  REMARK    GeneRIF: Eda and activin A are upstream regulators of Foxi3 in skin
            appendage placodes
REFERENCE   7  (bases 1 to 1206)
  AUTHORS   Urness,L.D., Paxton,C.N., Wang,X., Schoenwolf,G.C. and Mansour,S.L.
  TITLE     FGF signaling regulates otic placode induction and refinement by
            controlling both ectodermal target genes and hindbrain Wnt8a
  JOURNAL   Dev Biol 340 (2), 595-604 (2010)
   PUBMED   20171206
REFERENCE   8  (bases 1 to 1206)
  AUTHORS   Drogemuller,C., Karlsson,E.K., Hytonen,M.K., Perloski,M., Dolf,G.,
            Sainio,K., Lohi,H., Lindblad-Toh,K. and Leeb,T.
  TITLE     A mutation in hairless dogs implicates FOXI3 in ectodermal
            development
  JOURNAL   Science 321 (5895), 1462 (2008)
   PUBMED   18787161
REFERENCE   9  (bases 1 to 1206)
  AUTHORS   Zou,D., Silvius,D., Davenport,J., Grifone,R., Maire,P. and Xu,P.X.
  TITLE     Patterning of the third pharyngeal pouch into thymus/parathyroid by
            Six and Eya1
  JOURNAL   Dev Biol 293 (2), 499-512 (2006)
   PUBMED   16530750
REFERENCE   10 (bases 1 to 1206)
  AUTHORS   Ohyama,T. and Groves,A.K.
  TITLE     Expression of mouse Foxi class genes in early craniofacial
            development
  JOURNAL   Dev Dyn 231 (3), 640-646 (2004)
   PUBMED   15376323
  REMARK    GeneRIF: Foxi3 expressed in a broad region of the pan-placodal
            ectoderm adjacent to the neural plate from E6.75 to first somite
            stage; expression restricted to ectoderm & endoderm of branchial
            pouches at E10.5
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH466523.1.
            
            On or before Oct 4, 2008 this sequence version replaced
            XM_001477757.1, XM_144880.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384,
                              SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1206
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="mixed"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 32.14 cM"
     gene            1..1206
                     /gene="Foxi3"
                     /note="forkhead box I3"
                     /db_xref="GeneID:232077"
                     /db_xref="MGI:MGI:3511278"
     exon            1..595
                     /gene="Foxi3"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..1203
                     /gene="Foxi3"
                     /codon_start=1
                     /product="forkhead box protein I3"
                     /protein_id="NP_001094934.1"
                     /db_xref="CCDS:CCDS51804.1"
                     /db_xref="GeneID:232077"
                     /db_xref="MGI:MGI:3511278"
                     /translation="MALYCGDNFVYSQPAAAPGAPPTSRAPYGLSDYAAPPAAAANPY
                     LWLNGPGVGGPASAASYLGAPPPPPGAAPGPFLQPPAAPGTFAGAQRGFAQPSASAPA
                     SPAGSAAPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVA
                     DNFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNF
                     RRKRRRRAEASSNLTVPSGTSKSEGQSSRLRVSGKLEGDSPSSILRPSQSPEPPEGTK
                     STASSPGASTLTSTPCLNTFLSTFNTLNVNSSSSMGNQRTLPGSRRHLGGTQLPSSTF
                     PNTSVPDSSPDSMQLSTVGGSNQLSSYYNPFSGGSSGDQSSPFSSPFYNFSMVNSLIY
                     PRDGSDI"
     exon            596..1206
                     /gene="Foxi3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacatggccc tgtattgcgg cgacaacttc gtatactcgc agcccgccgc cgcgcctggt
       61 gcgcccccga cctccagggc accctatggg ctgtccgact acgccgcacc gcccgctgca
      121 gccgccaacc cctacctgtg gctcaatggg cccggcgtgg gcggcccagc ctccgctgcc
      181 agctacctag gggccccgcc gccgcctccc ggagctgcgc ccggaccctt cctgcagcct
      241 ccagccgctc cgggcacctt cgcgggcgcc cagcggggct tcgcgcagcc ctcggcgtcc
      301 gcacccgcct cgcccgccgg ctcggcagcc cctggcgagc tgggctggct gtcgatggcc
      361 agccgcgagg acctgatgaa gatggtgcga ccaccctact cgtactcggc gctcatcgct
      421 atggccatcc agagcgcgcc tgagcgcaaa ctcaccctca gccacattta ccagttcgtc
      481 gccgataact tccctttcta ccagcgcagc aaggccggct ggcagaactc catccgccac
      541 aacctatcac tcaacgactg ctttaagaag gtgccccgcg acgaggacga cccagggaag
      601 ggtaattact ggactctgga tccaaactgt gagaaaatgt tcgacaacgg aaacttccgt
      661 cggaagcgaa ggcgccgcgc ggaggccagc agtaacctta ctgtgccttc agggacatca
      721 aaatcagaag ggcagtcctc aagactaaga gtgagtggga agctggaagg agacagcccc
      781 tcttctatcc tgaggccatc tcagtcacca gagcctccag agggcaccaa gagtactgcc
      841 tcctctcctg gagcatccac cctcacctcc actccgtgtc tcaacacttt cctcagcacc
      901 tttaacacct taaatgtcaa ctccagcagc agcatgggca accagcgaac cctcccaggc
      961 agccgtcgcc acctaggagg gacccagctg ccctccagca cgttccccaa cacctccgtt
     1021 ccagacagtt ctccagactc catgcagctg agcactgtgg gtggaagcaa ccagctgtct
     1081 tcctactaca accctttctc tggtggcagc agtggggacc agagcagccc cttcagcagc
     1141 cctttctaca acttcagcat ggtcaacagc ctcatctacc cccgggatgg ctctgatata
     1201 tagaca
//
