LOCUS       NM_023907               2354 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus forkhead box I1 (Foxi1), mRNA.
ACCESSION   NM_023907
VERSION     NM_023907.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2354)
  AUTHORS   Kui,M., Pluznick,J.L. and Zaidman,N.A.
  TITLE     The transcription factor Foxi1 promotes expression of V-ATPase and
            Gpr116 in M-1 cells
  JOURNAL   Am J Physiol Renal Physiol 324 (3), F267-F273 (2023)
   PUBMED   36603001
  REMARK    GeneRIF: The transcription factor Foxi1 promotes expression of
            V-ATPase and Gpr116 in M-1 cells.
REFERENCE   2  (bases 1 to 2354)
  AUTHORS   Szeto,I.Y.Y., Chu,D.K.H., Chen,P., Chu,K.C., Au,T.Y.K.,
            Leung,K.K.H., Huang,Y.H., Wynn,S.L., Mak,A.C.Y., Chan,Y.S.,
            Chan,W.Y., Jauch,R., Fritzsch,B., Sham,M.H., Lovell-Badge,R. and
            Cheah,K.S.E.
  TITLE     SOX9 and SOX10 control fluid homeostasis in the inner ear for
            hearing through independent and cooperative mechanisms
  JOURNAL   Proc Natl Acad Sci U S A 119 (46), e2122121119 (2022)
   PUBMED   36343245
REFERENCE   3  (bases 1 to 2354)
  AUTHORS   Barone,S., Zahedi,K., Brooks,M., Henske,E.P., Yang,Y., Zhang,E.,
            Bissler,J.J., Yu,J.J. and Soleimani,M.
  TITLE     Kidney intercalated cells and the transcription factor FOXi1 drive
            cystogenesis in tuberous sclerosis complex
  JOURNAL   Proc Natl Acad Sci U S A 118 (6) (2021)
   PUBMED   33536341
  REMARK    GeneRIF: Kidney intercalated cells and the transcription factor
            FOXi1 drive cystogenesis in tuberous sclerosis complex.
REFERENCE   4  (bases 1 to 2354)
  AUTHORS   Mukherjee,M., DeRiso,J., Janga,M., Fogarty,E. and Surendran,K.
  TITLE     Foxi1 inactivation rescues loss of principal cell fate selection in
            Hes1-deficient kidneys but does not ensure maintenance of principal
            cell gene expression
  JOURNAL   Dev Biol 466 (1-2), 1-11 (2020)
   PUBMED   32800756
  REMARK    GeneRIF: Foxi1 inactivation rescues loss of principal cell fate
            selection in Hes1-deficient kidneys but does not ensure maintenance
            of principal cell gene expression.
REFERENCE   5  (bases 1 to 2354)
  AUTHORS   Montoro,D.T., Haber,A.L., Biton,M., Vinarsky,V., Lin,B.,
            Birket,S.E., Yuan,F., Chen,S., Leung,H.M., Villoria,J., Rogel,N.,
            Burgin,G., Tsankov,A.M., Waghray,A., Slyper,M., Waldman,J.,
            Nguyen,L., Dionne,D., Rozenblatt-Rosen,O., Tata,P.R., Mou,H.,
            Shivaraju,M., Bihler,H., Mense,M., Tearney,G.J., Rowe,S.M.,
            Engelhardt,J.F., Regev,A. and Rajagopal,J.
  TITLE     A revised airway epithelial hierarchy includes CFTR-expressing
            ionocytes
  JOURNAL   Nature 560 (7718), 319-324 (2018)
   PUBMED   30069044
REFERENCE   6  (bases 1 to 2354)
  AUTHORS   Hulander,M., Wurst,W., Carlsson,P. and Enerback,S.
  TITLE     The winged helix transcription factor Fkh10 is required for normal
            development of the inner ear
  JOURNAL   Nat Genet 20 (4), 374-376 (1998)
   PUBMED   9843211
REFERENCE   7  (bases 1 to 2354)
  AUTHORS   Overdier,D.G., Ye,H., Peterson,R.S., Clevidence,D.E. and Costa,R.H.
  TITLE     The winged helix transcriptional activator HFH-3 is expressed in
            the distal tubules of embryonic and adult mouse kidney
  JOURNAL   J Biol Chem 272 (21), 13725-13730 (1997)
   PUBMED   9153225
REFERENCE   8  (bases 1 to 2354)
  AUTHORS   Avraham,K.B., Fletcher,C., Overdier,D.G., Clevidence,D.E., Lai,E.,
            Costa,R.H., Jenkins,N.A. and Copeland,N.G.
  TITLE     Murine chromosomal location of eight members of the hepatocyte
            nuclear factor 3/fork head winged helix family of transcription
            factors
  JOURNAL   Genomics 25 (2), 388-393 (1995)
   PUBMED   7789972
REFERENCE   9  (bases 1 to 2354)
  AUTHORS   Clevidence,D.E., Overdier,D.G., Peterson,R.S., Porcella,A., Ye,H.,
            Paulson,K.E. and Costa,R.H.
  TITLE     Members of the HNF-3/forkhead family of transcription factors
            exhibit distinct cellular expression patterns in lung and regulate
            the surfactant protein B promoter
  JOURNAL   Dev Biol 166 (1), 195-209 (1994)
   PUBMED   7958446
REFERENCE   10 (bases 1 to 2354)
  AUTHORS   Clevidence,D.E., Overdier,D.G., Tao,W., Qian,X., Pani,L., Lai,E.
            and Costa,R.H.
  TITLE     Identification of nine tissue-specific transcription factors of the
            hepatocyte nuclear factor 3/forkhead DNA-binding-domain family
  JOURNAL   Proc Natl Acad Sci U S A 90 (9), 3948-3952 (1993)
   PUBMED   7683413
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK019994.1 and BF454473.1.
            
            On Apr 14, 2009 this sequence version replaced NM_023907.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019994.1, BC007475.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-261               AK019994.1         3-263
            262-262             BF454473.1         238-238
            263-2354            AK019994.1         265-2356
FEATURES             Location/Qualifiers
     source          1..2354
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 19.65 cM"
     gene            1..2354
                     /gene="Foxi1"
                     /gene_synonym="5830401E05Rik; Fkh10; FREAC6; HFH-3; Hfh3"
                     /note="forkhead box I1"
                     /db_xref="GeneID:14233"
                     /db_xref="MGI:MGI:1096329"
     exon            1..622
                     /gene="Foxi1"
                     /gene_synonym="5830401E05Rik; Fkh10; FREAC6; HFH-3; Hfh3"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1185
                     /gene="Foxi1"
                     /gene_synonym="5830401E05Rik; Fkh10; FREAC6; HFH-3; Hfh3"
                     /note="HNF-3/forkhead homolog 3; forkhead homolog 10"
                     /codon_start=1
                     /product="forkhead box protein I1"
                     /protein_id="NP_076396.3"
                     /db_xref="CCDS:CCDS24539.1"
                     /db_xref="GeneID:14233"
                     /db_xref="MGI:MGI:1096329"
                     /translation="MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGMPSP
                     QRPTSFEGGGEYGTTPNPYLWLNGPAMTPPPYLPGTNASPFLPQAYGMQRQLLPSDLG
                     WLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDQRLTLSQIYQYVADNFPFYNKSKAG
                     WQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDSSS
                     STSSLASEKTENGLLASSPKPTEPQEVLDTASPDTTTSSPEKRSSPAPSGTPCLNNFL
                     STMTAYVSGTNPISRSVATPGLSSEPIDKMGQNSLNFNSYTPLTNLSSHGNGGEWANP
                     VATNALGYGGSVFNQFSPHFYNSINTNGILFPREGTEV"
     exon            623..2354
                     /gene="Foxi1"
                     /gene_synonym="5830401E05Rik; Fkh10; FREAC6; HFH-3; Hfh3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcacctgtca ggggcagctc cagagaacac aggtgcggcc ggtggctacc cgaagccagc
       61 tccagcatga gctccttcga cctcccagcg ccttcaccac ctcggtgcag tccccagttc
      121 cccagcatcg gccaggagcc cccggagatg aatctttact atgagaattt cttccaccct
      181 cagggcatgc ccagtcctca gcgcccaacc tccttcgaag gtggtggcga atacgggacc
      241 actcccaacc cctacctctg gctcaatggg ccggccatga ccccaccacc ctacctgcct
      301 ggcactaacg ccagcccctt tctaccccag gcctatggca tgcagaggca gctactgccc
      361 agcgacctgg gctggctgcc catcccctct caggaagagc tcatgaagct ggtacgccca
      421 ccatattcct attcagccct cattgccatg gcaatccacg gtgcgcccga ccagcgcctc
      481 acactgagcc agatctacca gtacgtggcc gacaactttc ccttttacaa caagagcaag
      541 gctggctggc agaactccat ccgccacaac ctgtcactca acgactgctt caagaaggtg
      601 ccccgagatg aggacgaccc aggcaaaggg aattactgga ctctggaccc taactgtgag
      661 aagatgtttg acaacggaaa ctttcgcagg aagagaaaga gaaaatcaga ttcatcctcc
      721 agcaccagct cattggcttc agagaaaacg gagaacggtc tcctggccag cagccccaag
      781 cccacagagc ctcaggaggt cttagacacc gcctcgccag acactaccac cagctcccca
      841 gagaagcggt cctcccctgc cccctcgggc accccgtgtc tcaacaactt cctctccacc
      901 atgacagcat atgtgagtgg gacaaaccct attagccgct ccgtggccac accaggactg
      961 agctcagagc ctattgacaa gatggggcag aactcactga atttcaactc ctacaccccc
     1021 cttaccaacc tcagtagcca tgggaatggg ggtgaatggg ccaacccagt agccaccaat
     1081 gctctgggct atggaggctc cgtcttcaac cagttcagtc cacatttcta caacagcatt
     1141 aacactaacg gtatcctatt ccccagggaa ggcactgaag tctagagata gaacaacttc
     1201 tgttccatag agctgtctgg gggaaaagca aaggtggtcc ttcagaccag accctcaact
     1261 accccaaaat ttgagacgtt tgtccttccc agatagcacc ccaggaagct tggaagaatc
     1321 tgtgctcttt ctaaacagca ttcaagcctt ctggctatct atcacacgtg actctataca
     1381 gatttgataa ctacagtgag aacactaggg tcagcttgcc attaatgatg tggccattgg
     1441 ttgagcactt actatggtgc tggttcctgg tttgagcttt ttaatgacat agtcatactg
     1501 tgtaccatca tcctttgagg ttcacatgaa tctctccaat tgacagatca taaaacaaag
     1561 gcccaagaaa gttgtcagtt tttctagggt catgaaaatg acagagaaag gcattaaagc
     1621 agaggctggg tgaccttcga aggctggata aagggaaccg gggatggatg gactggatca
     1681 gaagtcagca taaagctggt tacggcaaat gcacgcacac tccccactgg cttctagtga
     1741 tgctctcaga attcaacacc catttggcca tgacatctcc ccacctgcct tttcttcttg
     1801 ccccagctta cctacaggca ttctgttacc taccactcag gaggaggagt ccagcccaaa
     1861 tacccctgta gaaccatgcc tctagtaggt gcaatacagg gtaacacttc actagccttc
     1921 cacagaactt gagcagagac agaggtcagt gagacaagtg gtatgtaccc ctgaaccctc
     1981 acccaagtac tgcccaccca caaaatctca taaccaccag cttcttgtat gtatgtgtca
     2041 tggatcagtg aagatgtggt ggctcagcct tccgagagaa acaaggtcaa atgagcagaa
     2101 taagcatgtc cttttttata gccctgtaga ggtggatact tgtctgagag aacaatggct
     2161 tggagggagg ggtcctctgc ctgccctgag ggcgggaggg gggaacagag tggctgtgag
     2221 cacagcctct ggcactgctc gctcctcttt tgtgagttac tttatttggt tgtgatgtca
     2281 tcacagcaca ccccacccgg agaagcgttg cttggtttcc ttattttctt tttaattaaa
     2341 aaaagaaaag aaag
//
