LOCUS       NM_010426               2440 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus forkhead box F1 (Foxf1), mRNA.
ACCESSION   NM_010426
VERSION     NM_010426.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2440)
  AUTHORS   Hudacova,E., Abaffy,P., Kaplan,M.M., Krausova,M., Kubista,M. and
            Machon,O.
  TITLE     Single-cell transcriptomic resolution of osteogenesis during
            craniofacial morphogenesis
  JOURNAL   Bone 190, 117297 (2025)
   PUBMED   39461490
REFERENCE   2  (bases 1 to 2440)
  AUTHORS   Zeng,H., Ali,S., Sebastian,A., Ramos-Medero,A.S., Albert,I.,
            Dean,C. and Liu,A.
  TITLE     CPLANE protein INTU regulates growth and patterning of the mouse
            lungs through cilia-dependent Hh signaling
  JOURNAL   Dev Biol 515, 92-101 (2024)
   PUBMED   39029571
REFERENCE   3  (bases 1 to 2440)
  AUTHORS   Oikonomakos,I., Tedesco,M., Motamedi,F.J., Peitzsch,M., Nef,S.,
            Bornstein,S.R., Schedl,A., Steenblock,C. and Neirijnck,Y.
  TITLE     In vitro differentiation of mouse pluripotent stem cells into
            corticosteroid-producing adrenocortical cells
  JOURNAL   Stem Cell Reports 19 (9), 1289-1303 (2024)
   PUBMED   39178848
REFERENCE   4  (bases 1 to 2440)
  AUTHORS   Shao,F., Phan,A.V., Yu,W., Guo,Y., Thompson,J., Coppinger,C.,
            Venugopalan,S.R., Amendt,B.A., Van Otterloo,E. and Cao,H.
  TITLE     Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling
            lineage specification of mandibular epithelium during tooth
            initiation
  JOURNAL   PLoS Genet 20 (7), e1011364 (2024)
   PUBMED   39052671
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2440)
  AUTHORS   Yoshida,S., Tsuneoka,Y., Tsukada,T., Nakakura,T., Kawamura,A.,
            Kai,W. and Yoshida,K.
  TITLE     Primary Cilia are Required for Cell-Type Determination and
            Angiogenesis in Pituitary Development
  JOURNAL   Endocrinology 165 (8) (2024)
   PUBMED   39001875
REFERENCE   6  (bases 1 to 2440)
  AUTHORS   Hellqvist,M., Mahlapuu,M., Samuelsson,L., Enerback,S. and
            Carlsson,P.
  TITLE     Differential activation of lung-specific genes by two forkhead
            proteins, FREAC-1 and FREAC-2
  JOURNAL   J Biol Chem 271 (8), 4482-4490 (1996)
   PUBMED   8626802
REFERENCE   7  (bases 1 to 2440)
  AUTHORS   Avraham,K.B., Fletcher,C., Overdier,D.G., Clevidence,D.E., Lai,E.,
            Costa,R.H., Jenkins,N.A. and Copeland,N.G.
  TITLE     Murine chromosomal location of eight members of the hepatocyte
            nuclear factor 3/fork head winged helix family of transcription
            factors
  JOURNAL   Genomics 25 (2), 388-393 (1995)
   PUBMED   7789972
REFERENCE   8  (bases 1 to 2440)
  AUTHORS   Clevidence,D.E., Overdier,D.G., Peterson,R.S., Porcella,A., Ye,H.,
            Paulson,K.E. and Costa,R.H.
  TITLE     Members of the HNF-3/forkhead family of transcription factors
            exhibit distinct cellular expression patterns in lung and regulate
            the surfactant protein B promoter
  JOURNAL   Dev Biol 166 (1), 195-209 (1994)
   PUBMED   7958446
REFERENCE   9  (bases 1 to 2440)
  AUTHORS   Pierrou,S., Hellqvist,M., Samuelsson,L., Enerback,S. and
            Carlsson,P.
  TITLE     Cloning and characterization of seven human forkhead proteins:
            binding site specificity and DNA bending
  JOURNAL   EMBO J 13 (20), 5002-5012 (1994)
   PUBMED   7957066
REFERENCE   10 (bases 1 to 2440)
  AUTHORS   Clevidence,D.E., Overdier,D.G., Tao,W., Qian,X., Pani,L., Lai,E.
            and Costa,R.H.
  TITLE     Identification of nine tissue-specific transcription factors of the
            hepatocyte nuclear factor 3/forkhead DNA-binding-domain family
  JOURNAL   Proc Natl Acad Sci U S A 90 (9), 3948-3952 (1993)
   PUBMED   7683413
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124170.3.
            
            On Feb 1, 2022 this sequence version replaced NM_010426.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC138805.1, ERR3363658.3273380.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1014              AC124170.3         226010-227023
            1015-2440           AC124170.3         228368-229793
FEATURES             Location/Qualifiers
     source          1..2440
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 70.31 cM"
     gene            1..2440
                     /gene="Foxf1"
                     /gene_synonym="Foxf1a; Freac-1; FREAC1; HFH-8; Hfh8"
                     /note="forkhead box F1"
                     /db_xref="GeneID:15227"
                     /db_xref="MGI:MGI:1347470"
     exon            1..1014
                     /gene="Foxf1"
                     /gene_synonym="Foxf1a; Freac-1; FREAC1; HFH-8; Hfh8"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1175
                     /gene="Foxf1"
                     /gene_synonym="Foxf1a; Freac-1; FREAC1; HFH-8; Hfh8"
                     /note="forkhead-related protein FKHL5; forkhead-related
                     transcription factor 1; hepatocyte nuclear factor 3
                     forkhead homolog 8; HNF-3/forkhead homolog 8; forkhead box
                     F1a"
                     /codon_start=1
                     /product="forkhead box protein F1"
                     /protein_id="NP_034556.2"
                     /db_xref="CCDS:CCDS22722.2"
                     /db_xref="GeneID:15227"
                     /db_xref="MGI:MGI:1347470"
                     /translation="MSAPDKQQPPHGGGTGGGGGAGGQAMDPAAAGPTKAKKTNAGVR
                     RPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSL
                     NECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPVYSMVNG
                     LGFNHLPDTYGFQGSGGLSCAPNSLALEGGLGMMNGHLAGNVDGMALPSHSVPHLPSN
                     GGHSYMGGCGGSAAGEYPHHDSSVPASPLLPAGAGGVMEPHAVYSSSAAAWPPAASAA
                     LNSGASYIKQQPLSPCNPAANPLSGSISTHSLEQPYLHQNSHNGPAELQGIPRYHSQS
                     PSMCDRKEFVFSFNAMASSSMHTTGGGSYYHQQVTYQDIKPCVM"
     exon            1015..2440
                     /gene="Foxf1"
                     /gene_synonym="Foxf1a; Freac-1; FREAC1; HFH-8; Hfh8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2418..2423
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxf1"
                     /gene_synonym="Foxf1a; Freac-1; FREAC1; HFH-8; Hfh8"
                     /note="hexamer: AATAAA"
     polyA_site      2440
                     /gene="Foxf1"
                     /gene_synonym="Foxf1a; Freac-1; FREAC1; HFH-8; Hfh8"
                     /note="major polyA site"
ORIGIN      
        1 agagcagcgg cggcagcggc ggcggcagca gccacccgat gtccgcgccc gacaagcagc
       61 agccgccgca cggcgggggc acaggaggag gcggcggcgc gggcggccag gccatggacc
      121 ccgcggcggc gggccccacc aaggccaaga agaccaacgc cggcgtgcgg cggccggaga
      181 agccgcccta ctcgtacatc gcgctcatcg tcatggctat ccagagctcg cccagcaagc
      241 gcctgaccct cagcgagatc taccagtttc ttcaggcgcg cttccccttc ttccgcggcg
      301 cctaccaggg ctggaagaac tccgtgcgcc acaacctgtc gctcaacgag tgcttcatca
      361 aactgcccaa gggcctcggg cgacccggca agggccacta ctggaccatc gatccggcta
      421 gcgagtttat gttcgaggag ggctcgttcc gccggcggcc gcgcggcttc cgaaggaaat
      481 gccaggcgct caagcctgtg tacagcatgg tgaacgggct gggcttcaac cacctccccg
      541 acacctacgg cttccagggc tccggaggcc tctcgtgcgc gcccaacagc ctggcgctgg
      601 agggcggctt gggcatgatg aatggccatt tggctggcaa cgtggacggc atggctttgc
      661 ccagccactc ggtgccacac ctgccctcca acggcggcca ctcgtacatg ggtggctgcg
      721 gtggctctgc ggccggggag tacccgcacc acgacagctc ggtgcccgct tcaccgctgc
      781 tgccggccgg cgccggcgga gtcatggagc cgcacgccgt ttactccagc tctgcagcag
      841 cctggccgcc cgcggcctcc gcggctctca acagcggggc ctcctacatc aagcaacagc
      901 ctctgtcccc ttgcaaccca gccgccaacc ccctgtctgg cagcatctcc acgcactccc
      961 tggagcagcc ataccttcac caaaacagtc acaacgggcc ggcagaactg caaggcatcc
     1021 ctcggtatca ctcacagtcg cccagcatgt gtgacagaaa ggagtttgtc ttctctttca
     1081 atgccatggc ctcttcttct atgcatacaa caggcggagg atcttactat caccagcagg
     1141 tcacctacca agacatcaag ccgtgtgtga tgtgaggtga ggccacgggg ccctccagcc
     1201 cagcctggcc ggcccaggga ccaggagccc accgccacaa actgctttac tctggaggta
     1261 taacccgtca gcaagtgaaa agggatagcc ccacccctaa cggattattt gtaaagaaaa
     1321 tcccaacaca gactgggagc agcgtctcta ccctcactcc ctcactaatt tctaaaaaaa
     1381 cagcggcagc cgggggccag gtcagactgc agctgtcagt aaataaatac tttcaacccc
     1441 actgaaacca gccacggagg tgctgtgtca tgtcggggga agccagatac gtggaaagaa
     1501 ttctgcagag gtctctccgc cccttccaca ccaagggaca gtttttagaa gcaggggaac
     1561 gtgagaccaa tcattatcaa atactttgat tttttttttt ggttgagtat ttatctttta
     1621 gtttttaact ttttgaaaga atgtcttgaa atgcacacat ctcccttccg ccatcttttt
     1681 ccccactccc ggggaggatg ggaccaggaa tggtctcccc tctcccaacc cggggtctcc
     1741 tccagcaatc acaggtgaat ctctatggga atggcacaca tacctggagc cactgtttgt
     1801 ctttttaaaa aggaaacagt gtcacagaag ttgctccagc cttcagccat ctattttttt
     1861 ttcgactcca gtgtctttca ccttgcttgg agttacattt tgacttttcc cctgggtgtt
     1921 cttctgtctc tactgtgact ctctgaaaag aaaggaacac actgagatga gggagtggag
     1981 ggtccatctg gctggtgtag ttcaggctca cactctgacg ccttggcagg cttggcctgt
     2041 tatttattct gctttacctt actactcaaa acaccacgta gctctgccct ctcagtatta
     2101 atggtgtgac ttggttggca atatttgccg tgtagagttg ttgtcattat tgtgggtttt
     2161 tttggttttt tgtttttgtt tttttttttt tagataacca ttgtaaattt gaaacaaaga
     2221 ccaatctgtg taaaaacaaa tttccatatg ttttatataa atatatataa tatgagggac
     2281 tgtcccccct tttagtcttt tggccgcaga ggtgcggcat ctgtgacacg tattttaaac
     2341 ctcctttctg cactgtataa aagggacaat ctgagggtat tgctttttgt gtattttttt
     2401 cctacaaaaa gaacaaaaat aaaaatgtat aacatttgta
//
