LOCUS       NM_010425               2373 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus forkhead box D3 (Foxd3), mRNA.
ACCESSION   NM_010425 XM_915082
VERSION     NM_010425.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2373)
  AUTHORS   Alvarez,S., Gupta,S., Mercado-Ayon,Y., Honeychurch,K.,
            Rodriguez,C., Kawaguchi,R. and Butler,S.J.
  TITLE     Netrin1 patterns the dorsal spinal cord through modulation of Bmp
            signaling
  JOURNAL   Cell Rep 43 (11), 114954 (2024)
   PUBMED   39547237
REFERENCE   2  (bases 1 to 2373)
  AUTHORS   Laddach,A., Chng,S.H., Lasrado,R., Progatzky,F., Shapiro,M.,
            Erickson,A., Sampedro Castaneda,M., Artemov,A.V.,
            Bon-Frauches,A.C., Amaniti,E.M., Kleinjung,J., Boeing,S.,
            Ultanir,S., Adameyko,I. and Pachnis,V.
  TITLE     A branching model of lineage differentiation underpinning the
            neurogenic potential of enteric glia
  JOURNAL   Nat Commun 14 (1), 5904 (2023)
   PUBMED   37737269
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2373)
  AUTHORS   Faucz,F.R., Horvath,A.D., Assie,G., Almeida,M.Q., Szarek,E.,
            Boikos,S., Angelousi,A., Levy,I., Maria,A.G., Chitnis,A.,
            Antonescu,C.R., Claus,R., Bertherat,J., Plass,C., Eng,C. and
            Stratakis,C.A.
  TITLE     Embryonic stem cell factor FOXD3 (Genesis) defects in
            gastrointestinal stromal tumors
  JOURNAL   Endocr Relat Cancer 30 (10), e230067 (2023)
   PUBMED   37578265
  REMARK    GeneRIF: Embryonic stem cell factor FOXD3 (Genesis) defects in
            gastrointestinal stromal tumors.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2373)
  AUTHORS   Yan,H., Meng,Y., Li,X., Xiang,R., Hou,S., Wang,J., Wang,L., Yu,X.,
            Xu,M., Chi,Y. and Yang,J.
  TITLE     FAM3A maintains metabolic homeostasis by interacting with F1-ATP
            synthase to regulate the activity and assembly of ATP synthase
  JOURNAL   Metabolism 139, 155372 (2023)
   PUBMED   36470472
REFERENCE   5  (bases 1 to 2373)
  AUTHORS   Bellchambers,H.M., Barratt,K.S., Diamand,K.E.M. and Arkell,R.M.
  TITLE     SUMOylation Potentiates ZIC Protein Activity to Influence Murine
            Neural Crest Cell Specification
  JOURNAL   Int J Mol Sci 22 (19), 10437 (2021)
   PUBMED   34638777
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2373)
  AUTHORS   Xu,D., Yoder,M., Sutton,J. and Hromas,R.
  TITLE     Forced expression of Genesis, a winged helix transcriptional
            repressor isolated from embryonic stem cells, blocks granulocytic
            differentiation of 32D myeloid cells
  JOURNAL   Leukemia 12 (2), 207-212 (1998)
   PUBMED   9519783
REFERENCE   7  (bases 1 to 2373)
  AUTHORS   Sutton,J., Costa,R., Klug,M., Field,L., Xu,D., Largaespada,D.A.,
            Fletcher,C.F., Jenkins,N.A., Copeland,N.G., Klemsz,M. and Hromas,R.
  TITLE     Genesis, a winged helix transcriptional repressor with expression
            restricted to embryonic stem cells
  JOURNAL   J Biol Chem 271 (38), 23126-23133 (1996)
   PUBMED   8798505
REFERENCE   8  (bases 1 to 2373)
  AUTHORS   Avraham,K.B., Fletcher,C., Overdier,D.G., Clevidence,D.E., Lai,E.,
            Costa,R.H., Jenkins,N.A. and Copeland,N.G.
  TITLE     Murine chromosomal location of eight members of the hepatocyte
            nuclear factor 3/fork head winged helix family of transcription
            factors
  JOURNAL   Genomics 25 (2), 388-393 (1995)
   PUBMED   7789972
REFERENCE   9  (bases 1 to 2373)
  AUTHORS   Clevidence,D.E., Overdier,D.G., Peterson,R.S., Porcella,A., Ye,H.,
            Paulson,K.E. and Costa,R.H.
  TITLE     Members of the HNF-3/forkhead family of transcription factors
            exhibit distinct cellular expression patterns in lung and regulate
            the surfactant protein B promoter
  JOURNAL   Dev Biol 166 (1), 195-209 (1994)
   PUBMED   7958446
REFERENCE   10 (bases 1 to 2373)
  AUTHORS   Clevidence,D.E., Overdier,D.G., Tao,W., Qian,X., Pani,L., Lai,E.
            and Costa,R.H.
  TITLE     Identification of nine tissue-specific transcription factors of the
            hepatocyte nuclear factor 3/forkhead DNA-binding-domain family
  JOURNAL   Proc Natl Acad Sci U S A 90 (9), 3948-3952 (1993)
   PUBMED   7683413
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF067421.2, BX005053.5, AI323053.1 and W87115.1.
            
            On Aug 19, 2006 this sequence version replaced NM_010425.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               AF067421.2         1-110
            111-771             BX005053.5         153212-153872       c
            772-1176            AI323053.1         32-436
            1177-2255           BX005053.5         151728-152806       c
            2256-2373           W87115.1           1-118               c
FEATURES             Location/Qualifiers
     source          1..2373
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 45.71 cM"
     gene            1..2373
                     /gene="Foxd3"
                     /gene_synonym="CWH3; Genesis; Hfh2"
                     /note="forkhead box D3"
                     /db_xref="GeneID:15221"
                     /db_xref="MGI:MGI:1347473"
     exon            1..2373
                     /gene="Foxd3"
                     /gene_synonym="CWH3; Genesis; Hfh2"
                     /inference="alignment:Splign:2.1.0"
     CDS             327..1736
                     /gene="Foxd3"
                     /gene_synonym="CWH3; Genesis; Hfh2"
                     /note="HFH-2; HNF3/FH transcription factor genesis;
                     hepatocyte nuclear factor 3 forkhead homolog 2;
                     HNF-3/forkhead homolog 2"
                     /codon_start=1
                     /product="forkhead box protein D3"
                     /protein_id="NP_034555.3"
                     /db_xref="CCDS:CCDS18383.1"
                     /db_xref="GeneID:15221"
                     /db_xref="MGI:MGI:1347473"
                     /translation="MTLSGSGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGC
                     DSPAGPPDLRLDEADEGPPVSAHHGQSQPQALALPTEATGPGNDTGAPEADGCKGGED
                     AVTGGGGPGAGSGATGGLTPNKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEF
                     ISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNG
                     SFLRRRKRFKRHQQEHLREQTALMMQSFGAYSLAAAAGAGPYGRPYGLHPAAAAGAYS
                     HPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPSLQLQL
                     NTLGAAAAAAGTAGAAGTTSLIKSEPSARPSFSIENIIGAGSAAPGGSAGGGGSGGGA
                     GGGGGSGGGGGAQSFLRPPGTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQP
                     AASAAAAAAAAVQAKWPAQ"
ORIGIN      
        1 gtcgaggaag gctggtgaag tgagggggtg cggcgtggag aaacctccgg ggtcgcgagc
       61 agtagctgtc tcctcgtaga gaagcgtcga ggaccgcaag agttcgcgga gcgcggctgc
      121 ggagcgcagc gcccgcaccg cgcgatgcca ggcctcctcg tgtgagctga cccgacaggg
      181 ccccgagcta cctgtgccct ctcccccccc cccggctttc tttcggggga cactcacacc
      241 tcctttgcct gagctccgcg gccgcccctc gcggcccccc tcgctctctg ctcgctcctg
      301 gccgccgcca ccaaccccgc ggagggatga ccctctccgg cagcggcagc gccagcgata
      361 tgtccggcca gacggtgctg acggccgagg acgtggacat cgatgtggtg ggcgagggcg
      421 acgacgggct ggaggagaag gacagcgacg ccgggtgcga cagccccgcg gggcctccgg
      481 acctgcgcct ggacgaggcg gacgaagggc caccggtgag cgctcatcac ggccagtctc
      541 aaccgcaagc cctggcactg cccaccgagg cgaccgggcc ggggaacgac acgggagctc
      601 cggaggccga cggctgcaag ggcggcgagg acgcggtgac aggcggcggt gggcccggcg
      661 cgggcagcgg ggcgacggga ggtctgaccc cgaacaagcc caagaacagc ctggtgaagc
      721 caccctactc ttacatcgcg ctcatcacca tggccatcct gcagagcccg cagaagaagc
      781 tgaccctgag cggcatctgc gagttcatca gcaaccgttt tccgtactac cgggagaagt
      841 tccccgcctg gcagaacagc atccgccaca acctgtcgct caacgactgc ttcgtcaaga
      901 tcccccgcga gccgggcaac ccgggcaagg gcaactactg gaccctggac ccccagtccg
      961 aggacatgtt cgacaacggc agcttcctgc ggcgccggaa gcgcttcaag cgccaccagc
     1021 aggagcacct gcgcgagcag acggcgctga tgatgcagag cttcggagcc tacagcctgg
     1081 cggcggcggc gggcgcagga ccctacggcc gcccctacgg cctgcacccc gcggcggctg
     1141 cgggcgccta ctcgcacccc gcggcggcgg cggcggccgc ggctgctgcg gcgctccagt
     1201 acccgtacgc gctaccaccc gtggctcccg tgctgccgcc cgcagtgccc ctgctgccct
     1261 cgggcgagct gggccgcaaa gcggccgcct tcggctcgca gctcggtccg agcctgcagc
     1321 tacagctcaa caccctgggc gccgccgcgg cagccgcggg cacggcgggc gcggcgggca
     1381 ccacgtcgct catcaagtcc gagcccagtg cgcggccgtc gttcagcatc gagaacatca
     1441 taggcgcggg atccgcggcg cccgggggct cggctggggg tggtgggagc ggcggcggag
     1501 ccgggggtgg cgggggcagt gggggcggcg gcggcgcgca gtccttcctg cggccgcccg
     1561 ggactgtgca gtcggctgcg ctcatggcca cgcaccagcc cctgtcgctg agccggacga
     1621 ctgccaccat cgcgcccatt ctgagcgtgc cgctgtctgg acagttcctg cagcccgcag
     1681 cctcagccgc agcggctgcg gccgccgccg tgcaagccaa gtggcccgct caatagtgat
     1741 gagctagtgg ccgggccgga cggcggcctc tggcagcagc ctgctcttcc aggcggtacg
     1801 ccctctctga tcctggtcca tctgtcctgg tcctggtcct ggtccctcta cccaatcctg
     1861 gactctgcta cccgcccccg actccccaac actgaccaac agcggcctcc atcccctcac
     1921 tcacctaagc tggcggagca aactcaaccc gcgtccgctg ggaataactt tccgtacagg
     1981 taaaactgat aaccgaattt ccaaaaatgc accccgacgg cgcctgtgtt ctcagtactg
     2041 tgggggtggg agggacattc tttgtacata tttgtataaa aatcattgac tttccttttg
     2101 gggtttttat ttttttaaga aaataaaaag caattcagta gatttagagc tttgaacttt
     2161 catatttttt tgaaggttca ctctgcgcag ttttatctga gaaaaagaat gtataaagac
     2221 gttgggagat tttaaatcca aaaaaaattt ttcaaaaagg cgaagtgtca ttgtattata
     2281 aaagtctgtt tatatatgaa tgaatatata tggtattcta aatgttattc catcgtgttg
     2341 tacacaattt tgtaaataaa tttttaaaat gct
//
