LOCUS       NM_008242               2461 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus forkhead box D1 (Foxd1), mRNA.
ACCESSION   NM_008242 XM_913730
VERSION     NM_008242.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2461)
  AUTHORS   Hudacova,E., Abaffy,P., Kaplan,M.M., Krausova,M., Kubista,M. and
            Machon,O.
  TITLE     Single-cell transcriptomic resolution of osteogenesis during
            craniofacial morphogenesis
  JOURNAL   Bone 190, 117297 (2025)
   PUBMED   39461490
REFERENCE   2  (bases 1 to 2461)
  AUTHORS   Hampl,M., Jandova,N., Luskova,D., Novakova,M., Szotkowska,T.,
            Cada,S., Prochazka,J., Kohoutek,J. and Buchtova,M.
  TITLE     Early embryogenesis in CHDFIDD mouse model reveals facial clefts
            and altered cranial neurogenesis
  JOURNAL   Dis Model Mech 17 (6) (2024)
   PUBMED   38511331
REFERENCE   3  (bases 1 to 2461)
  AUTHORS   Nikoloudaki,G. and Hamilton,D.W.
  TITLE     Assessing the fate and contribution of Foxd1-expressing embryonic
            precursors and their progeny in palatal development, homeostasis
            and excisional repair
  JOURNAL   Sci Rep 14 (1), 4969 (2024)
   PUBMED   38424240
  REMARK    GeneRIF: Assessing the fate and contribution of Foxd1-expressing
            embryonic precursors and their progeny in palatal development,
            homeostasis and excisional repair.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2461)
  AUTHORS   Qiu,C., Martin,B.K., Welsh,I.C., Daza,R.M., Le,T.M., Huang,X.,
            Nichols,E.K., Taylor,M.L., Fulton,O., O'Day,D.R., Gomes,A.R.,
            Ilcisin,S., Srivatsan,S., Deng,X., Disteche,C.M., Noble,W.S.,
            Hamazaki,N., Moens,C.B., Kimelman,D., Cao,J., Schier,A.F.,
            Spielmann,M., Murray,S.A., Trapnell,C. and Shendure,J.
  TITLE     A single-cell time-lapse of mouse prenatal development from
            gastrula to birth
  JOURNAL   Nature 626 (8001), 1084-1093 (2024)
   PUBMED   38355799
REFERENCE   5  (bases 1 to 2461)
  AUTHORS   Langner,E., Cheng,T., Kefaloyianni,E., Gluck,C., Wang,B. and
            Mahjoub,M.R.
  TITLE     Cep120 is essential for kidney stromal progenitor cell growth and
            differentiation
  JOURNAL   EMBO Rep 25 (1), 428-454 (2024)
   PUBMED   38177914
REFERENCE   6  (bases 1 to 2461)
  AUTHORS   Hatini,V., Huh,S.O., Herzlinger,D., Soares,V.C. and Lai,E.
  TITLE     Essential role of stromal mesenchyme in kidney morphogenesis
            revealed by targeted disruption of Winged Helix transcription
            factor BF-2
  JOURNAL   Genes Dev 10 (12), 1467-1478 (1996)
   PUBMED   8666231
REFERENCE   7  (bases 1 to 2461)
  AUTHORS   Avraham,K.B., Fletcher,C., Overdier,D.G., Clevidence,D.E., Lai,E.,
            Costa,R.H., Jenkins,N.A. and Copeland,N.G.
  TITLE     Murine chromosomal location of eight members of the hepatocyte
            nuclear factor 3/fork head winged helix family of transcription
            factors
  JOURNAL   Genomics 25 (2), 388-393 (1995)
   PUBMED   7789972
REFERENCE   8  (bases 1 to 2461)
  AUTHORS   Pierrou,S., Hellqvist,M., Samuelsson,L., Enerback,S. and
            Carlsson,P.
  TITLE     Cloning and characterization of seven human forkhead proteins:
            binding site specificity and DNA bending
  JOURNAL   EMBO J 13 (20), 5002-5012 (1994)
   PUBMED   7957066
REFERENCE   9  (bases 1 to 2461)
  AUTHORS   Hatini,V., Tao,W. and Lai,E.
  TITLE     Expression of winged helix genes, BF-1 and BF-2, define adjacent
            domains within the developing forebrain and retina
  JOURNAL   J Neurobiol 25 (10), 1293-1309 (1994)
   PUBMED   7815060
REFERENCE   10 (bases 1 to 2461)
  AUTHORS   Clevidence,D.E., Overdier,D.G., Tao,W., Qian,X., Pani,L., Lai,E.
            and Costa,R.H.
  TITLE     Identification of nine tissue-specific transcription factors of the
            hepatocyte nuclear factor 3/forkhead DNA-binding-domain family
  JOURNAL   Proc Natl Acad Sci U S A 90 (9), 3948-3952 (1993)
   PUBMED   7683413
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK132390.1 and AK142034.1.
            
            On Sep 7, 2007 this sequence version replaced NM_008242.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK132390.1, AK164408.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-494               AK132390.1         1-494
            495-2461            AK142034.1         499-2465
FEATURES             Location/Qualifiers
     source          1..2461
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 51.96 cM"
     gene            1..2461
                     /gene="Foxd1"
                     /gene_synonym="BF-2; FREAC4; Hfh10; Hfhbf2"
                     /note="forkhead box D1"
                     /db_xref="GeneID:15229"
                     /db_xref="MGI:MGI:1347463"
     exon            1..2461
                     /gene="Foxd1"
                     /gene_synonym="BF-2; FREAC4; Hfh10; Hfhbf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             376..1746
                     /gene="Foxd1"
                     /gene_synonym="BF-2; FREAC4; Hfh10; Hfhbf2"
                     /note="FREAC-4; HFH-BF-2; brain factor 2; forkhead-related
                     protein FKHL8; forkhead-related transcription factor 4;
                     HNF-3/forkhead homolog, brain factor 2; FORKHEAD BOX
                     PROTEIN D1 (FORKHEAD-RELATED PROTEIN FKHL8)
                     (FORKHEAD-RELATED TRANSCRIPTION FACTOR 4) (FREAC-4)"
                     /codon_start=1
                     /product="forkhead box protein D1"
                     /protein_id="NP_032268.2"
                     /db_xref="CCDS:CCDS36759.1"
                     /db_xref="GeneID:15229"
                     /db_xref="MGI:MGI:1347463"
                     /translation="MTLSTEMSDASGLAEETDIDVVGEGEDDEEEEDDDDEGGGGRGG
                     GGSRLPSSAQRRRRSYAGEDDLEDLEEEDDDDLLLASRPAASPAPPGPAPAPGTGSGG
                     CSGAGAGGGAGGGTGAGTGGGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFI
                     SSRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGS
                     FLRRRKRFKRQPLLAPHAAAEALLLRGAGPAAGAGDPGAALFPPPPPPPACGYGAYGC
                     AYGLQLPPCAPPSALFAAAAAAAAAAFHPHSPPPPPPPPPPPPGAAAELARTAFGYRS
                     HALAAALPGPLQAAAVKAGGPGAAALARSPFSIESLIGRTRGPAAAGAHVSSGAASGT
                     APGPGGGGCAVQAAAGPAVALTRSLVVAAAAAASSVSSSAALGTLHQGTALSSVENFT
                     ARISNC"
     regulatory      2426..2431
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Foxd1"
                     /gene_synonym="BF-2; FREAC4; Hfh10; Hfhbf2"
                     /note="hexamer: AATAAA"
     polyA_site      2461
                     /gene="Foxd1"
                     /gene_synonym="BF-2; FREAC4; Hfh10; Hfhbf2"
                     /note="major polyA site"
ORIGIN      
        1 actcagccct ggccttgccg agctccgttt ctagattctc actcctcccg cgcccttctg
       61 ggcgcccgac accgactggc ccgccagggt ccagccaccc cctcctggac taaccgggct
      121 aaagggacca cagtggaaaa ggtcaagtct agagcgcccg ccacccggtg cccgccgagc
      181 cggggagcgc aaacacctcg cacagccctg ctcgccaagt agcggagcgg agcggcccca
      241 gccacctcct gcagccgcgc gtcgcagagt ggcgtcctcg ctccgggtcc gccgctccgg
      301 gatcggcctg gggaggccag ggagccggga gcccggtgcc cctatgtgcc gccgcgccac
      361 cgcgccgccc cagctatgac cctgagcacg gagatgtccg atgcctccgg cctcgcggag
      421 gagacagaca tcgacgtggt gggggagggc gaggacgacg aggaggagga ggacgatgac
      481 gacgagggcg gcggcggccg cggcggcggc gggtcccggt tgccgagctc ggcccagcgg
      541 cggaggcgct cttacgccgg ggaggacgat ctcgaggacc tggaggagga ggacgacgat
      601 gacctgctgc tggcctcccg gcccgccgcg tcccccgcgc ctccgggtcc tgcgcccgcc
      661 ccggggaccg ggtcgggcgg ctgcagcggc gccggagcgg gaggcggcgc gggaggtggt
      721 acgggcgcgg gcacgggcgg gggcgctaag aatccgctgg tgaagccgcc ctactcgtac
      781 atcgcgctca tcaccatggc catcctgcag agccccaaga agcgcctgac gctcagcgag
      841 atctgcgagt tcatcagcag ccgcttccct tactaccggg agaagttccc cgcttggcag
      901 aacagcatcc gtcacaacct gtcgctcaac gactgcttcg tcaagatccc gcgcgaaccg
      961 ggcaacccgg gcaagggcaa ctactggacg ctcgacccgg agtccgcaga tatgttcgac
     1021 aacggcagct tcctgcggcg ccgcaagcgc ttcaagcgcc agccgctact cgctccccac
     1081 gcggcggccg aggcgctgct gctgcgcggt gcggggccgg cggcgggcgc aggggacccg
     1141 ggcgccgcgc ttttcccgcc gccgccgcca ccgcccgcct gcggctacgg agcctacggc
     1201 tgcgcctacg gcctgcagct gccaccctgc gcgccgccct ccgcgctctt cgctgccgcc
     1261 gccgcggcag ccgccgccgc cttccatccg cactcgcccc cgccgcctcc tcctcctccg
     1321 ccgccgcctc ccggtgcggc cgccgagctg gcgcggaccg ccttcggcta ccggtcacac
     1381 gcgctggctg ccgccctgcc cggccctttg caggcggccg cagtcaaggc gggaggcccg
     1441 ggcgccgcag cgctcgcacg ctcgcccttc tccatcgaga gcctcatcgg gcgcactcgg
     1501 ggtcccgcgg ccgccggggc gcacgtctcg tccggggccg ccagcgggac cgccccggga
     1561 cccgggggcg ggggttgcgc agtacaggcg gctgctggtc ccgccgtcgc gctcacccgc
     1621 tcgctcgtgg tcgccgccgc ggccgccgcc tcctccgtgt cctcgtccgc cgcgctgggg
     1681 actctgcacc aagggacagc gctgtccagt gtggagaact ttactgctag gatttccaat
     1741 tgttaggaac gtcgttagcg cgcgggagag cgaaggtagg actcccggct tctttctccg
     1801 gatggggggg ttggtttcgt tcgcccctcc cggtcctcgg agaccccgcg ccccccattt
     1861 tcgccgcttc ggattcttgg accagactgt gttgggcgac agctggggcg ccgcgcagtt
     1921 tagctcagag ggtccatcta tttatgcaaa atcgccctat gctgcaaccc tgacttgggg
     1981 tgggaaggag gggagtcgct ctgtcttggc actaggaatt tccttgactt ttgacaaatt
     2041 gagaaaaaac aaaacaaaac aagcaaaatc atcaaaacta agcccttttt gaggtgtaga
     2101 gattctcagg tccaggcgtt ttaaaaaatc agtaatgttt aaatgcagct tatagaaaac
     2161 cagtaaaagt ctccaagaaa tgcctctact tgttcacact tgtttggtag acttttttca
     2221 tggaaagaaa aaaaattaac atgtttacac aagaaataag tcgaaattta ccatttccta
     2281 tttttaacct gtgttttgta tcataatgga catgcggaat ttttattttg tacttactac
     2341 gtattctttg caaggagtat tgtaaatttt actggcaatt attattgtac tattctaatg
     2401 taagattttt acactttttt tcagaaataa aatgcttaat tttcaaagaa aagccaccta
     2461 a
//
