LOCUS       NM_008023               1515 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus forkhead box B2 (Foxb2), mRNA.
ACCESSION   NM_008023
VERSION     NM_008023.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1515)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1515)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1515)
  AUTHORS   Everson,J.L., Fink,D.M., Yoon,J.W., Leslie,E.J., Kietzman,H.W.,
            Ansen-Wilson,L.J., Chung,H.M., Walterhouse,D.O., Marazita,M.L. and
            Lipinski,R.J.
  TITLE     Sonic hedgehog regulation of Foxf2 promotes cranial neural crest
            mesenchyme proliferation and is disrupted in cleft lip
            morphogenesis
  JOURNAL   Development 144 (11), 2082-2091 (2017)
   PUBMED   28506991
REFERENCE   4  (bases 1 to 1515)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 1515)
  AUTHORS   Hammock,E.A., Eagleson,K.L., Barlow,S., Earls,L.R., Miller,D.M. 3rd
            and Levitt,P.
  TITLE     Homologs of genes expressed in Caenorhabditis elegans GABAergic
            neurons are also found in the developing mouse forebrain
  JOURNAL   Neural Dev 5, 32 (2010)
   PUBMED   21122108
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1515)
  AUTHORS   Lein,E.S., Hawrylycz,M.J., Ao,N., Ayres,M., Bensinger,A.,
            Bernard,A., Boe,A.F., Boguski,M.S., Brockway,K.S., Byrnes,E.J.,
            Chen,L., Chen,L., Chen,T.M., Chin,M.C., Chong,J., Crook,B.E.,
            Czaplinska,A., Dang,C.N., Datta,S., Dee,N.R., Desaki,A.L.,
            Desta,T., Diep,E., Dolbeare,T.A., Donelan,M.J., Dong,H.W.,
            Dougherty,J.G., Duncan,B.J., Ebbert,A.J., Eichele,G., Estin,L.K.,
            Faber,C., Facer,B.A., Fields,R., Fischer,S.R., Fliss,T.P.,
            Frensley,C., Gates,S.N., Glattfelder,K.J., Halverson,K.R.,
            Hart,M.R., Hohmann,J.G., Howell,M.P., Jeung,D.P., Johnson,R.A.,
            Karr,P.T., Kawal,R., Kidney,J.M., Knapik,R.H., Kuan,C.L.,
            Lake,J.H., Laramee,A.R., Larsen,K.D., Lau,C., Lemon,T.A.,
            Liang,A.J., Liu,Y., Luong,L.T., Michaels,J., Morgan,J.J.,
            Morgan,R.J., Mortrud,M.T., Mosqueda,N.F., Ng,L.L., Ng,R.,
            Orta,G.J., Overly,C.C., Pak,T.H., Parry,S.E., Pathak,S.D.,
            Pearson,O.C., Puchalski,R.B., Riley,Z.L., Rockett,H.R.,
            Rowland,S.A., Royall,J.J., Ruiz,M.J., Sarno,N.R., Schaffnit,K.,
            Shapovalova,N.V., Sivisay,T., Slaughterbeck,C.R., Smith,S.C.,
            Smith,K.A., Smith,B.I., Sodt,A.J., Stewart,N.N., Stumpf,K.R.,
            Sunkin,S.M., Sutram,M., Tam,A., Teemer,C.D., Thaller,C.,
            Thompson,C.L., Varnam,L.R., Visel,A., Whitlock,R.M.,
            Wohnoutka,P.E., Wolkey,C.K., Wong,V.Y., Wood,M., Yaylaoglu,M.B.,
            Young,R.C., Youngstrom,B.L., Yuan,X.F., Zhang,B., Zwingman,T.A. and
            Jones,A.R.
  TITLE     Genome-wide atlas of gene expression in the adult mouse brain
  JOURNAL   Nature 445 (7124), 168-176 (2007)
   PUBMED   17151600
REFERENCE   7  (bases 1 to 1515)
  AUTHORS   Kenney-Hunt,J.P., Vaughn,T.T., Pletscher,L.S., Peripato,A.,
            Routman,E., Cothran,K., Durand,D., Norgard,E., Perel,C. and
            Cheverud,J.M.
  TITLE     Quantitative trait loci for body size components in mice
  JOURNAL   Mamm Genome 17 (6), 526-537 (2006)
   PUBMED   16783635
REFERENCE   8  (bases 1 to 1515)
  AUTHORS   Wijchers,P.J., Hoekman,M.F., Burbach,J.P. and Smidt,M.P.
  TITLE     Identification of forkhead transcription factors in cortical and
            dopaminergic areas of the adult murine brain
  JOURNAL   Brain Res 1068 (1), 23-33 (2006)
   PUBMED   16376864
REFERENCE   9  (bases 1 to 1515)
  AUTHORS   Kaestner,K.H., Schutz,G. and Monaghan,A.P.
  TITLE     Expression of the winged helix genes fkh-4 and fkh-5 defines
            domains in the central nervous system
  JOURNAL   Mech Dev 55 (2), 221-230 (1996)
   PUBMED   8861101
REFERENCE   10 (bases 1 to 1515)
  AUTHORS   Kaestner,K.H., Lee,K.H., Schlondorff,J., Hiemisch,H., Monaghan,A.P.
            and Schutz,G.
  TITLE     Six members of the mouse forkhead gene family are developmentally
            regulated
  JOURNAL   Proc Natl Acad Sci U S A 90 (16), 7628-7631 (1993)
   PUBMED   7689224
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125185.3.
            
            On Jan 22, 2019 this sequence version replaced NM_008023.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: X92591.1, BC139477.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1515              AC125185.3         164683-166197       c
FEATURES             Location/Qualifiers
     source          1..1515
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 12.26 cM"
     gene            1..1515
                     /gene="Foxb2"
                     /gene_synonym="Fkh4"
                     /note="forkhead box B2"
                     /db_xref="GeneID:14240"
                     /db_xref="MGI:MGI:1347468"
     exon            1..1515
                     /gene="Foxb2"
                     /gene_synonym="Fkh4"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..1477
                     /gene="Foxb2"
                     /gene_synonym="Fkh4"
                     /note="transcription factor FKH-4; forkhead homolog 4"
                     /codon_start=1
                     /product="forkhead box protein B2"
                     /protein_id="NP_032049.1"
                     /db_xref="CCDS:CCDS29686.1"
                     /db_xref="GeneID:14240"
                     /db_xref="MGI:MGI:1347468"
                     /translation="MPRPGKSSYSDQKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIM
                     ERFPYYREHTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPDCGDMFENGSF
                     LRRRKRFKVLRADHAHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHH
                     HHPPQPPPPPPPHMVPYFHQQPAPAPQPPHLPSQPAQQPQPQSQPPQTSHPGKMQEAA
                     AVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTTGFKHPFAIENIIGRD
                     YKGVLQAGGLPLASVMHHLGYPVPGQLSNVVGSVWPHVGVMDSVAAAAAAAAAAGVPV
                     GPEYGAFGVPVKALCHSANQSLPAVPVPIKPTPALPPVTTLPPALSVPTASQQLPAPS
                     TVCAAAASPTAPLLEPTAAGRADSKGSSLHSVLVHS"
ORIGIN      
        1 ttgcggggac ccggggcagc tccccgaagg aggaggacca aggcaaaagg ggtctgggga
       61 ccaagaaagc tggggatcag gctgcgcagg tggagagaga attagtgggg acacttaagc
      121 ctggtatccg gctttccgag aggcgttaag gcccactgtg ggccggacgg aagtggaaga
      181 gcctgggaag atgccacggc cagggaagag ttcctacagc gaccaaaagc cgccctactc
      241 ttacatctca ctgaccgcca tggccatcca gcattcggct gagaagatgc tgcctctgag
      301 cgacatctac aagttcatca tggagcgctt cccctactac cgcgagcaca cgcagcgctg
      361 gcagaacagc ctgcgccaca acctctcctt caacgactgt ttcatcaaga tccctcggag
      421 gccggaccaa cccggtaagg gcagcttctg ggcgctacac cctgactgcg gtgacatgtt
      481 cgagaacggc agcttcctgc ggcgccgcaa gcgcttcaag gtgctacgcg cagaccacgc
      541 tcacctacac tcaggaagca gcaagggcgc gcccggcacg gggccaggag gtcacctgca
      601 tccccaccat ccccaccacg cacaccacca ccaccaccat caccaccacg ccgcacacca
      661 tcaccaccat caccacccgc cgcagccgcc cccgccgccg ccgccgcaca tggtgcccta
      721 tttccaccag cagccggctc cggctccgca gcctccacac ctcccgtcgc agcccgcgca
      781 gcagccacag ccgcagtcgc agcctccgca gacgtcccat cccggcaaga tgcaggaggc
      841 ggcggccgtg gcggcggccg cagcagcggc ggcggccgca gcggtgggca gcgtggggcg
      901 tctgtctcag ttcccaccct acgggctggg ctcggccgcc gccgccgccg ctgcagccgc
      961 cgcgtccacc acaggcttca aacatccgtt cgccatagag aacatcatcg ggcgggacta
     1021 caagggcgtg ctgcaggctg gagggttgcc tttggcgtcg gtcatgcacc acttgggcta
     1081 ccccgtgccg ggccagctca gcaatgttgt cggctccgtg tggcctcatg ttggcgtgat
     1141 ggattcggta gccgcggctg ccgctgctgc cgccgcagct ggggtcccgg taggcccgga
     1201 gtatggggca ttcggggtgc cagtcaaggc tctgtgccac tcggcaaacc agagcctgcc
     1261 agctgtaccg gtgcccatca agcccacgcc tgcgctacca cccgtgacca cgctgccgcc
     1321 ggcgttgtct gtccccacgg cgtcgcagca gctgcctgct ccctccaccg tgtgcgcggc
     1381 cgccgcctca cccacagccc ctctcttgga gcccaccgca gccggcaggg ctgacagcaa
     1441 ggggagctcc ctacactcgg tgttggtgca ttcttagggg accccgcgac cggtgagaag
     1501 gcgcctgtcg agaga
//
