LOCUS       NM_010235               1705 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus fos-like antigen 1 (Fosl1), mRNA.
ACCESSION   NM_010235
VERSION     NM_010235.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1705)
  AUTHORS   Zerad,L., Gacem,N., Gayda,F., Day,L., Sinigaglia,K., Richard,L.,
            Parisot,M., Cagnard,N., Mathis,S., Bole-Feysot,C., O'Connell,M.A.,
            Pingault,V., Dambroise,E., Keegan,L.P., Vallat,J.M. and
            Bondurand,N.
  TITLE     Overexpression of Egr1 Transcription Regulator Contributes to
            Schwann Cell Differentiation Defects in Neural Crest-Specific Adar1
            Knockout Mice
  JOURNAL   Cells 13 (23), 1952 (2024)
   PUBMED   39682701
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1705)
  AUTHORS   Li,A.L., Sugiura,K., Nishiwaki,N., Suzuki,K., Sadeghian,D.,
            Zhao,J., Maitra,A., Falvo,D., Chandwani,R., Pitarresi,J.R.,
            Sims,P.A. and Rustgi,A.K.
  TITLE     FRA1 controls acinar cell plasticity during murine KrasG12D-induced
            pancreatic acinar to ductal metaplasia
  JOURNAL   Dev Cell 59 (22), 3025-3042 (2024)
   PUBMED   39178842
REFERENCE   3  (bases 1 to 1705)
  AUTHORS   Bakiri,L., Hasenfuss,S.C., Guio-Carrion,A., Thomsen,M.K.,
            Hasselblatt,P. and Wagner,E.F.
  TITLE     Liver cancer development driven by the AP-1/c-Jun Fra-2 dimer
            through c-Myc
  JOURNAL   Proc Natl Acad Sci U S A 121 (18), e2404188121 (2024)
   PUBMED   38657045
REFERENCE   4  (bases 1 to 1705)
  AUTHORS   Xu,X., Bok,I., Jasani,N., Wang,K., Chadourne,M., Mecozzi,N.,
            Deng,O., Welsh,E.A., Kinose,F., Rix,U. and Karreth,F.A.
  TITLE     PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by
            Opposing an AKT/mTOR/FRA1 Signaling Axis
  JOURNAL   Cancer Res 84 (3), 388-404 (2024)
   PUBMED   38193852
  REMARK    GeneRIF: PTEN Lipid Phosphatase Activity Suppresses Melanoma
            Formation by Opposing an AKT/mTOR/FRA1 Signaling Axis.
REFERENCE   5  (bases 1 to 1705)
  AUTHORS   Astrof,S., Arriagada,C., Saijoh,Y., Francou,A., Kelly,R.G. and
            Moon,A.
  TITLE     Aberrant differentiation of second heart field mesoderm prefigures
            cellular defects in the outflow tract in response to loss of FGF8
  JOURNAL   Dev Biol 499, 10-21 (2023)
   PUBMED   37060937
REFERENCE   6  (bases 1 to 1705)
  AUTHORS   Poirier,C., Blot,S., Fernandes,M., Carle,G.F., Stanescu,V.,
            Stanescu,R. and Guenet,J.L.
  TITLE     A high-resolution genetic map of mouse chromosome 19 encompassing
            the muscle-deficient osteochondrodystrophy (mdf-ocd) region
  JOURNAL   Mamm Genome 9 (5), 390-391 (1998)
   PUBMED   9545499
REFERENCE   7  (bases 1 to 1705)
  AUTHORS   Schreiber,M., Poirier,C., Franchi,A., Kurzbauer,R., Guenet,J.L.,
            Carle,G.F. and Wagner,E.F.
  TITLE     Structure and chromosomal assignment of the mouse fra-1 gene, and
            its exclusion as a candidate gene for oc (osteosclerosis)
  JOURNAL   Oncogene 15 (10), 1171-1178 (1997)
   PUBMED   9294610
REFERENCE   8  (bases 1 to 1705)
  AUTHORS   Huo,L. and Rothstein,T.L.
  TITLE     Isolation and characterization of murine fra-1: induction mediated
            by CD40 and surface Ig is protein kinase C dependent
  JOURNAL   J Immunol 157 (9), 3812-3818 (1996)
   PUBMED   8892610
REFERENCE   9  (bases 1 to 1705)
  AUTHORS   Jeske,Y.W., Mishina,Y., Cohen,D.R., Behringer,R.R. and Koopman,P.
  TITLE     Analysis of the role of Amh and Fra1 in the Sry regulatory pathway
  JOURNAL   Mol Reprod Dev 44 (2), 153-158 (1996)
   PUBMED   9115712
REFERENCE   10 (bases 1 to 1705)
  AUTHORS   Carrasco,D. and Bravo,R.
  TITLE     Tissue-specific expression of the fos-related transcription factor
            fra-2 during mouse development
  JOURNAL   Oncogene 10 (6), 1069-1079 (1995)
   PUBMED   7700631
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC122861.4.
            
            On Nov 17, 2006 this sequence version replaced NM_010235.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144839.1, AK144785.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-358               AC122861.4         182203-182560
            359-550             AC122861.4         184665-184856
            551-658             AC122861.4         188918-189025
            659-1705            AC122861.4         189397-190443
FEATURES             Location/Qualifiers
     source          1..1705
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.33 cM"
     gene            1..1705
                     /gene="Fosl1"
                     /gene_synonym="fra-1; Fra1"
                     /note="fos-like antigen 1"
                     /db_xref="GeneID:14283"
                     /db_xref="MGI:MGI:107179"
     exon            1..358
                     /gene="Fosl1"
                     /gene_synonym="fra-1; Fra1"
                     /inference="alignment:Splign:2.1.0"
     CDS             254..1075
                     /gene="Fosl1"
                     /gene_synonym="fra-1; Fra1"
                     /codon_start=1
                     /product="fos-related antigen 1"
                     /protein_id="NP_034365.1"
                     /db_xref="CCDS:CCDS29464.1"
                     /db_xref="GeneID:14283"
                     /db_xref="MGI:MGI:107179"
                     /translation="MYRDYGEPGPSSGAGSPYGRPAQPPQAQAQTAQQQKFHLVPSID
                     SSSQELHWMVQPHFLGPTGYPRPLAYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISP
                     EEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKER
                     LELVLEAHRPICKIPEGDKKDPGGSGSTSGASSPPAPGRPVPCISLSPGPVLEPEALH
                     TPTLMTTPSLTPFTPSLVFTYPSTPEPCSSAHRKSSSSSGDPSSDPLGSPTLLAL"
     exon            359..550
                     /gene="Fosl1"
                     /gene_synonym="fra-1; Fra1"
                     /inference="alignment:Splign:2.1.0"
     exon            551..658
                     /gene="Fosl1"
                     /gene_synonym="fra-1; Fra1"
                     /inference="alignment:Splign:2.1.0"
     exon            659..1705
                     /gene="Fosl1"
                     /gene_synonym="fra-1; Fra1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtctgtaga ggcggcttgc cacccgagca gagggtcgtg aagttccgag cggaccggtc
       61 cacagaggtt catctggaga ggtgggtccc ctgcgaggtg aaaggcgccg ctgagacacg
      121 cccccacccc ccgtggtgca agtggttcag cccaagaact tttcattcat aaaaaagacc
      181 agactccgag aggcgcgagt gagtcagaac cgcagccgcc aacgcggacc ctaccgaaca
      241 tccagcccag ggcatgtacc gagactacgg ggaaccggga ccgagctccg gggctggcag
      301 cccgtacggt cgccccgcgc agcccccgca agctcaggca cagaccgccc agcagcagaa
      361 gttccacctt gtgccaagca tcgacagcag cagccaggaa ctgcactgga tggtgcagcc
      421 tcatttcctg ggacccactg gctatccccg acctctggcc tatccccagt acagtccccc
      481 tcagccccgg ccaggagtca tacgagccct agggccacct ccgggggtgc gtcgcaggcc
      541 ctgcgagcag atcagcccag aggaggaaga gcgccgcagg gtgagacgcg agcggaacaa
      601 gctagcagct gctaagtgca gaaaccgaag aaaggagctg acagacttcc tgcaggcgga
      661 gaccgacaaa ttggaggatg agaaatcggg gctgcagcga gagattgaag agctgcagaa
      721 gcagaaggaa cgccttgagc tggtgctgga agcccatcgc cccatctgca aaatcccaga
      781 aggagacaag aaggacccag gtggttctgg cagcaccagc ggtgctagca gcccaccagc
      841 ccccggccgc ccagtgcctt gcatctccct ttctccagga cccgtacttg aaccggaagc
      901 actgcatacc cccacgctca tgaccacacc ctctctgact ccttttactc cgagtctggt
      961 tttcacctat cctagcacac cagaaccttg ctcctccgct caccgaaaga gtagcagcag
     1021 cagtggcgac ccctcctccg accccctggg ctctcctaca ctcctggctt tgtgaggcac
     1081 ccagccacat cccttgctgg tgctactcca agccatcccc tttctcccat tgatccagca
     1141 ggcctggacc atacccttgc cccaaaccag cagatctttt atctcttccg actagaacaa
     1201 acacattatg ctttgatgta gagccagctt ggaggggatc cccaaagctg ctcactgttt
     1261 ttctagagct ggcctatcat aatttgcaca aaattagagg aaaatatgtt ccctctgcca
     1321 gagaacgcct ggcagcccag actttgtaga tccccagggg tcctttgaca cccttacccc
     1381 ttgcagacca ctttcccaca ccacgtcact ttcttcatgt tatccagcct actctacacc
     1441 tagacagaag gtgccctttg actagcctag aacactaact cacacagcat caacagccag
     1501 cagcaccgga catcctgcag gctcctcctg aatggcacaa cgcaggaggc gccaggggct
     1561 tctgtgagga gcggagctgc actccctagc tctgagaagc gcttagcttc agggtatccg
     1621 agcctccacc gcaagggcag ctgctattta ttttcctaaa gagactattt ttatacaaac
     1681 cttccaaaat ggaataaaag gcttg
//
