LOCUS       NM_001405166            8037 bp    mRNA    linear   ROD 17-JUL-2024
DEFINITION  Mus musculus folliculin interacting protein 2 (Fnip2), transcript
            variant 2, mRNA.
ACCESSION   NM_001405166 XM_006501594
VERSION     NM_001405166.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8037)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8037)
  AUTHORS   Shillingford,J.M. and Shayman,J.A.
  TITLE     Functional TFEB activation characterizes multiple models of renal
            cystic disease and loss of polycystin-1
  JOURNAL   Am J Physiol Renal Physiol 324 (4), F404-F422 (2023)
   PUBMED   36794754
REFERENCE   3  (bases 1 to 8037)
  AUTHORS   Fernandez,L.P., Deleyto-Seldas,N., Colmenarejo,G., Sanz,A.,
            Wagner,S., Plata-Gomez,A.B., Gomez-Patino,M., Molina,S.,
            Espinosa-Salinas,I., Aguilar-Aguilar,E., Ortega,S.,
            Grana-Castro,O., Loria-Kohen,V., Fernandez-Marcos,P.J., Efeyan,A.
            and Ramirez de Molina,A.
  TITLE     Folliculin-interacting protein FNIP2 impacts on overweight and
            obesity through a polymorphism in a conserved 3' untranslated
            region
  JOURNAL   Genome Biol 23 (1), 230 (2022)
   PUBMED   36316722
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8037)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8037)
  AUTHORS   Hasumi,H., Baba,M., Hasumi,Y., Lang,M., Huang,Y., Oh,H.F.,
            Matsuo,M., Merino,M.J., Yao,M., Ito,Y., Furuya,M., Iribe,Y.,
            Kodama,T., Southon,E., Tessarollo,L., Nagashima,K., Haines,D.C.,
            Linehan,W.M. and Schmidt,L.S.
  TITLE     Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles
            in kidney tumor suppression in cooperation with Flcn
  JOURNAL   Proc Natl Acad Sci U S A 112 (13), E1624-E1631 (2015)
   PUBMED   25775561
  REMARK    GeneRIF: Fnip1 and Fnip2 play critical roles in kidney tumor
            suppression in cooperation with Flcn
REFERENCE   6  (bases 1 to 8037)
  AUTHORS   Lim,T.H., Fujikane,R., Sano,S., Sakagami,R., Nakatsu,Y.,
            Tsuzuki,T., Sekiguchi,M. and Hidaka,M.
  TITLE     Activation of AMP-activated protein kinase by MAPO1 and FLCN
            induces apoptosis triggered by alkylated base mismatch in DNA
  JOURNAL   DNA Repair (Amst) 11 (3), 259-266 (2012)
   PUBMED   22209521
  REMARK    GeneRIF: The involvement of the AMPK-MAPO1-FLCN complex in the
            signaling pathway of apoptosis, is described.
REFERENCE   7  (bases 1 to 8037)
  AUTHORS   Komori,K., Takagi,Y., Sanada,M., Lim,T.H., Nakatsu,Y., Tsuzuki,T.,
            Sekiguchi,M. and Hidaka,M.
  TITLE     A novel protein, MAPO1, that functions in apoptosis triggered by
            O6-methylguanine mispair in DNA
  JOURNAL   Oncogene 28 (8), 1142-1150 (2009)
   PUBMED   19137017
REFERENCE   8  (bases 1 to 8037)
  AUTHORS   Hasumi,H., Baba,M., Hong,S.B., Hasumi,Y., Huang,Y., Yao,M.,
            Valera,V.A., Linehan,W.M. and Schmidt,L.S.
  TITLE     Identification and characterization of a novel
            folliculin-interacting protein FNIP2
  JOURNAL   Gene 415 (1-2), 60-67 (2008)
   PUBMED   18403135
REFERENCE   9  (bases 1 to 8037)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113945.26 and AC142502.3.
            
            On Apr 20, 2022 this sequence version replaced XM_006501594.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223969.3776.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1301              AC113945.26        84545-85845
            1302-1428           AC113945.26        99197-99323
            1429-1575           AC113945.26        102139-102285
            1576-1676           AC113945.26        104790-104890
            1677-1748           AC113945.26        104986-105057
            1749-1849           AC113945.26        109201-109301
            1850-1939           AC113945.26        109460-109549
            1940-2011           AC113945.26        111110-111181
            2012-2141           AC113945.26        116921-117050
            2142-2343           AC113945.26        123911-124112
            2344-2432           AC113945.26        124468-124556
            2433-2579           AC113945.26        127996-128142
            2580-2749           AC113945.26        128260-128429
            2750-4070           AC142502.3         5194-6514
            4071-4227           AC142502.3         7430-7586
            4228-4428           AC142502.3         21325-21525
            4429-4544           AC142502.3         24829-24944
            4545-8037           AC142502.3         27332-30824
FEATURES             Location/Qualifiers
     source          1..8037
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 34.91 cM"
     gene            1..8037
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /note="folliculin interacting protein 2"
                     /db_xref="GeneID:329679"
                     /db_xref="MGI:MGI:2683054"
     exon            1..1301
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     CDS             1126..4623
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /note="isoform 2 is encoded by transcript variant 2;
                     FNIP1-like protein; O6-methylguanine-induced apoptosis 1
                     protein"
                     /codon_start=1
                     /product="folliculin-interacting protein 2 isoform 2"
                     /protein_id="NP_001392095.1"
                     /db_xref="GeneID:329679"
                     /db_xref="MGI:MGI:2683054"
                     /translation="MCGGTADSTNWPVGQQESARCLTDTTCGAGRIFKTLVCAKIPKC
                     ARGGRDTNSTVLNHSWSCSEFGLSDIRLLVYQDCERRGRQVMFDSRAVQKMEEAAAQK
                     AEDVPIKMSARCCQESSSSSGSSSSGSSSSHGFGGSLQHAKQQLPKYQYTRPASDVSM
                     LGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSATMGSFCGSTNNLQDSFEYINQ
                     DPQAGKLNTNQYNLGPFRTGSNLGLLQVCSGKLLQGLSEGGPLRLTRSASFFAAHSTP
                     VDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSSSSYQRRWLRSQTTSLENG
                     IFPRRSTDETFSLAEETCSSNPAMVRRKKIAISIIFSLCEREAAQRDFQDFFFSHFPL
                     FESHMNRLKGAIEKAMISCRKISESSLRVQFYVSRLMEALGEFRGTIWNLYSVPRIAE
                     PVWLTMMSNTLEKNQLCQRFLKEFILLIEQVNKNQFFAALLTAVLTYHLAWVPTVMPV
                     DHPPIKAFSEKRTSQSVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVIGKQKDL
                     VQRILYVLTYFLRCSELQENQLSWSGNPSEDDQVINGSKIITALEKGEVEESEYVVVT
                     VSSEPALVPPILPQGTAERRSPEPTVVAEISEGVNTSELGHKPEKNRCKRPEQNSEAS
                     SMGFQEAEPDSSWIPQGIFCEDKQNDQEATQDCSSSPPSCEVPRVRRRMDQQTLHSKL
                     HGETLKKRAEQSAAWPCPDRHSQEDPPVEKVTFHIGSSISPESDFESRTKRMEERLKA
                     CGHFHGASASASSSMDTGLTQEQQGSGCSFKADFEKDITPQDHSSGGEGVSEDRGLRA
                     NMTHAVGQLSQVDGPLAHSLCAAESGRRLLEQTRDVQLKGYKGPSSEPVPNRCRQQGG
                     LLIAADVPYGDASGKGNYRSEGDIPRNESLDSALGDSDDEACVLALLELGHSCDRTEE
                     SLEVELPLPRSQSTSKANVRNFGRSLLAGYCATYMPDLVLHGTSSDEKLKQCLAADLV
                     HTVHHPVLDEPIAEAVCIIADTDKWTVQVATSQRKVTDTMKLGQDVLVSSQVSSLLQS
                     ILQLYKLHLPADFCIMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELSVVLGIESNDL
                     PLLTAIASTHSPYVAQILL"
     exon            1302..1428
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1575
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1676
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1748
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1849
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            1850..1939
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2011
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2141
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2343
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            2344..2432
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            2433..2579
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            2580..2749
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..4070
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            4071..4227
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            4228..4428
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            4429..4544
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     exon            4545..8037
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8010..8015
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /note="hexamer: AATAAA"
     polyA_site      8037
                     /gene="Fnip2"
                     /gene_synonym="D630023B12Rik; mKIAA1450"
                     /note="major polyA site"
ORIGIN      
        1 agttcatgga gggtggcggg ttccggtcca atgtacggca tgtaaaatgt cttaaatcaa
       61 ctgaggtctg ggcctggcat ccctagtttt ccttacctta aattagtggg taatttataa
      121 agatactttt aggactaaga ccatagagcc agccaatggt tcacctcacc ttagggatgg
      181 acccagtagt actttcttca acctaattcc aggcaaaagg aattggtatc atcactctgc
      241 tgttggtttc tagccttgac ctgtgtttag gggatcacca gctcaaattt atctcctaac
      301 actcccatat ccaggtgagc tatgttgatg tcagaagcta gcactgttct agggctctgg
      361 taattcaggg ctttctcagc ttgaataagc ccaggaattc aaatgcaaga gttagaaggc
      421 tttttaccat cagttgcctc tcatcatcat tactttcccc catccccact cataccatgg
      481 ccagagtgtg ccccagctct gcttctcatc ccacacgtct ccttctacat attaagatct
      541 ccattcgact cttgtgggta gccatccttc actcactgtg gacagagttt tgcaaggttg
      601 tggagtagaa gctgtcagct gatacttact cacatgagaa ccattaagag ggtggtgcgg
      661 ccaatgtcag agcaaccttg cagctgaagg tttacccaga gccacatgag ctgggctcgt
      721 gactagtgaa ggcagggctg cttgtaaact cagctcgaga tgcagatggt gtgagtcagt
      781 gcaagctgct ggacctgttg agtgcacttg agtgcaggcg gagaaaaagc agggagagat
      841 ttgtacttgt ctactttatt atgggtttac tgagagcaca tccgcttcta gaagtcatcc
      901 tgggcttcat ttgcatgatg aatgaacatc ccttttttta agctcccaaa agaggaagtt
      961 agtagtagct gggctcacgt gctgtgcttg gagggaaatg gtctttagtc tggagctgct
     1021 gctcgtcacc gtggcatatc cttcagataa tgaaggaact ttacagagtg ggctagtcca
     1081 cactgctggt caggatcaac tgaagagcat ctatgccctc aggagatgtg tggtggtaca
     1141 gcagacagca caaactggcc agtaggccaa caggagtcag ccagatgtct gaccgatacc
     1201 acttgtggtg ctgggaggat tttcaagaca cttgtatgtg caaagattcc aaaatgtgcc
     1261 agaggaggac gcgacacaaa ttccacagtg ctcaaccaca gttggtcgtg ttcggagttt
     1321 ggcttgagtg acatccgcct gctagtttac caggactgtg agaggagagg cagacaagtc
     1381 atgtttgact ccagagccgt tcagaagatg gaagaggcag cagctcagaa agcagaggat
     1441 gttcctatta aaatgtcagc cagatgctgt caggaaagca gcagcagcag cggcagcagc
     1501 agcagcggca gcagctcttc tcatggcttt ggaggatctt tacaacacgc taagcaacag
     1561 cttccaaagt accaatacac gagaccagca tctgatgtca gcatgcttgg ggagatgatg
     1621 tttggctcag ttgcaatgag ttacaaaggc tccaccctga agatacacta catacgatct
     1681 cctccacaac tgatgattag taaagtcttt tctgctacaa tgggtagctt ctgtggaagt
     1741 acaaataatc tgcaggacag cttcgaatac attaaccaag atcctcaggc tggaaaactg
     1801 aacacaaatc agtacaattt gggtcctttt cgtactggaa gtaacctagg tctgctgcag
     1861 gtgtgcagcg gcaaactgct gcaggggttg tctgaaggag gacctctccg gctcacccgg
     1921 agcgcttctt tctttgcagc acacagcaca cctgttgata tgccaagcag agggcagaat
     1981 gaagacaggg acagcggcat tgctcgatca gcttcactga gcagcctttt gatcacgccc
     2041 ttcccgtctc caagctcttc tacatcctct tccagcagtt accagcgccg ctggctccga
     2101 agtcagacaa cgagtttgga aaatggcatc tttccaagga ggtcaactga tgagacattt
     2161 agcttggccg aagaaacgtg tagctctaat ccagctatgg ttagaaggaa gaagatcgcc
     2221 atcagcatca tcttttccct gtgtgagaga gaggccgccc agcgggattt ccaggacttc
     2281 tttttctccc acttccccct gtttgaatct cacatgaaca ggctgaaggg tgcaatcgaa
     2341 aaggccatga tctcctgtag gaagatctct gaatcaagtc tccgagtcca gttctatgtg
     2401 agccgtctga tggaagcact gggagaattc agagggacta tctggaactt atattctgtt
     2461 ccaaggatag ctgaaccagt ttggcttacc atgatgtcaa acaccttgga gaaaaaccaa
     2521 ctctgccagc gctttctcaa ggaatttata cttctgattg aacaagtcaa caaaaaccag
     2581 ttttttgctg ccttactgac tgcggtgtta acctaccacc tggcctgggt accaactgtc
     2641 atgcctgttg accaccctcc cattaaagcc ttctcggaga agcgtacctc tcagtcagtg
     2701 aacatgctgg ccaaaacaca tccatataat cctctctggg cgcagctggg tgacctctat
     2761 ggagctatag gctctccggt gagactgact cgcactgtgg tgattgggaa gcagaaggat
     2821 ttggtccagc gcattcttta tgttctgacc tactttctcc gttgctctga actgcaagag
     2881 aatcagctga gctggagtgg aaatcccagt gaggatgacc aggttataaa tgggagcaag
     2941 ataataaccg ccctggaaaa gggagaggtg gaagagtctg agtatgtggt agttaccgtg
     3001 agcagtgagc ctgccctggt accaccaatc ctaccacagg ggacagctga gaggaggagc
     3061 cctgagccta cagtagtagc tgagatctcg gaaggcgtta atactagcga actgggtcac
     3121 aaacctgaaa agaacagatg caagaggcca gagcagaatt ccgaggccag tagtatgggc
     3181 ttccaagagg cagaacctga cagttcgtgg atacctcaag gcatattctg tgaggacaaa
     3241 cagaatgacc aagaggcaac ccaggattgt tcttcaagtc ctcccagctg tgaggtgccc
     3301 agggtaagaa ggaggatgga ccaacaaacc ctccactcga agctgcatgg ggagacgcta
     3361 aagaagcgag cagagcagtc cgcagcctgg ccctgcccag acaggcattc ccaggaggat
     3421 cctcctgtcg aaaaggtcac tttccacatt gggagttcca tctccccgga gtctgacttt
     3481 gaaagccgga ccaaaagaat ggaggagcga ttaaaggcct gtggacattt ccatggggct
     3541 agtgcctctg ccagctctag catggacact gggctgactc aagagcagca gggctctggg
     3601 tgctccttca aagctgactt tgaaaaggac atcacgcctc aggaccactc ttcagggggg
     3661 gaaggtgtct ctgaggacag aggcctccgg gccaacatga cacatgctgt gggacaactt
     3721 agccaagttg atggccccct tgcacattcc ctttgtgccg cagaaagtgg gcggagactg
     3781 ctggaacaga ctagagatgt gcaattaaaa ggctacaaag gaccttcatc ggagcctgtt
     3841 ccaaacagat gtagacagca gggtggcctg ctgattgctg cagatgtccc ctatggggat
     3901 gccagtggta agggcaacta caggagcgaa ggagacattc ccaggaacga gagcttggat
     3961 agtgctcttg gagacagtga tgatgaagcg tgtgtcttag ccctgctaga actaggtcac
     4021 agttgtgaca ggactgaaga gtccttggaa gtggagctgc ctctgccaag gtctcagagc
     4081 accagcaagg caaatgttag aaattttggc cgctcacttc tggcaggtta ctgtgccacg
     4141 tacatgcctg atctggtgct gcatggaacc agcagcgatg agaagctgaa gcagtgcctg
     4201 gcagctgatc tggtccacac ggtgcaccat ccagtactcg atgagcccat agccgaagct
     4261 gtctgtatca ttgcagacac tgacaagtgg actgtccagg tggccacgag tcagcggaag
     4321 gtgacggaca ccatgaagct gggccaggat gtcttggtct ccagtcaggt gtccagttta
     4381 cttcagtcca tcttacagct ctataagctt cacctccctg ctgatttttg tatcatgcat
     4441 ctggaagaca gactgcagga gatgtacctg aagagtaaaa tgctttcaga gtatctccgg
     4501 ggacacacgc gtgtgcacgt gaaagagctg agtgtggtgc tggggatcga atccaatgac
     4561 ctgcctctgc tgacggccat cgccagcact cactctccgt acgtggcaca gatcctctta
     4621 tagccgacta caggacagct ctcattggaa aatgagacag gatggagggt gctctcagtg
     4681 acggcagagg cgtgagaaca cggagcaggc acccctcgtt gttcctgtgg ctgctgccta
     4741 gtggctctta cattgggaag cttgtgtcta ctccatgcag tgggagtttg tgattgttca
     4801 ggaacagtcg acattgtctc ccaggaatca aaagaaagta acctttctgg caggagggaa
     4861 gtgtaagcaa cactgtcaaa ctagacagac gtgcccatgc tgttgggtag aatactgagg
     4921 gctgactctg agtagtgggt aaccaatgtc tagaacattc cagaaggaaa gtgtttcctg
     4981 ttcaagcgtg agagagcatg aagagttgct ctaagaacgg gttgtggctt ctaggtcaga
     5041 gctcttctac gaacattgac ctgaagaaag ccatgttgtg ccactgtcag cctggagctc
     5101 cagcagctac tgttggacat aggatgtgga agagggttgc ctattgagaa gagagtgctc
     5161 cagaaaccca cggttgtcac ttctcagagc ttcctgtaga ctcagcacag ccacctgcag
     5221 gtctgcgagg gactcagtgt agcaccctgt cctgccgggt attttggagg acgtagtctg
     5281 gcactgggaa ctcatctctg gctttagtat ctttagcctt ctccagaaag accttttacc
     5341 aaagttgttt ccatgagctc aggcgatctt ctgtggctga gctcgcccag cgcaagcctc
     5401 tttcttccta gccggctgtg cagatgtctg tttgtgctgt atggggccgc tgccagctgg
     5461 ggagtggact tgctctgata aggatagcag gcagcccgaa catttatgtg atccacaagc
     5521 gatctaggtt tttatatgat cagttctgca ctttttaatc cctctcatat tctttaaaaa
     5581 aaaatctttc tagaaattaa cttgaccatt tgtaaaactt accaaagtga cgaactgtaa
     5641 aaacccaact gatcattgaa cctacagaac cttagtttac tgaccataag acagtccatg
     5701 ttcaaatact ttaaaaacaa aacttctgct gtttaaaaga caggagccag tcaagtaaag
     5761 tcaaaccctg tgggctcctc agtccttccc accagtccct ggtgcctgag aatgtgggac
     5821 agcaaatcct gatccatgtg acatgtctgt ctcctcatta caaatacaag ttagtggaga
     5881 ccatgtgccc cttacgctac tggggacgaa tgcctacatc atctcttaga agtgggccgg
     5941 agtgtggacg ctctggaccc cctccctccc tttcctctct tcctccccct ctcgccctga
     6001 gcatctctca ttttttgtga tatgtaaaaa taggtggttc ttccaggccc ttaagatctt
     6061 taatttgcat ttttgtgttt cacaaagttg aagtgtccta ttcttttaca tctctttcca
     6121 ctttctatca cctggcattt gtttgctgtt ttccatttcc tggctccatg gtaccattgt
     6181 ttgccaggga gccccacatg tggcccgctg agctgtcaat gcagatttcc tagacaccgg
     6241 tgccagctta gagctcgccc ttctttctcc tggcttctct cgtttacaca tggactcggc
     6301 ctcaccagct cctgaggatt gggagaaaat agctcagtac agaatcagtt tggtcctcgt
     6361 gcagatgtag tgacatgttg acagctagac tcggggaatt gagctgtcac caggttaatt
     6421 ctcagcttca tgaagaaaga cttagcccag cacttcaaag cctgaaaaaa attaaacctg
     6481 cctcttaatc tagtgttcca aatttcagaa gaaaagtggg aaaccctggg ctcacgtggg
     6541 ttatctcagc gccccaccat cacttgcaag aaagatgcgc tgctcttctc ctggctcccc
     6601 cggtgcgggc gatgacgatg acgtgtcctt tgtcttaaat tcatcctctt ctcagaggcg
     6661 gggaaaacag taaacaaagc atctcatgga cctgtgctga cgcggatgct gtcattctgt
     6721 catagccgaa gagtccgaaa aggtgtccca cctaggcata actcaagggg aaaaatcttt
     6781 ttttaatgtt taaagaaatc tacctcagtt gacaggattc cacctgccct agggtttctt
     6841 cagctcttca gtcttacctg ttaggtgtca ctgggcagcg ctctgcttgt ctgaccaagc
     6901 aggctggcga ggcacagccg agcagaagtg tctcagtgtc ctgtaatgac ctcttctagc
     6961 atgttgcagt tttatatttg ttaagttgat aagtgatatg aatgtatagg caattgtgta
     7021 tgttttcaaa aaggacaatg aaaatttaaa atgtagcttc cacacttgtg cataattcca
     7081 aagtatctta ttttatcagt gttaaatagc ttttgtacag cttcagccca ttttccagac
     7141 gtgtgctgtt ttatacggga agtaactcat gatctcactc acggagctgt gtttacacat
     7201 cgcaaatttt taacttaatg tgtttttcag aattaacttt tttggaggga ggaaattccc
     7261 cacttgctaa atgatactaa actgttgtct ggactcttaa gaatcaggtc tttggatttt
     7321 ataaactagt ctgtagcttt ttaggttctt cattggttgg atgtacatag agaatataaa
     7381 acaactctca gattctttta agcgtctgaa gttttccttg gatgcacact cggtcgggta
     7441 ttatgttcac gcagactttc agcattaaat tgaaaaggtc caccgcttct cttagttaat
     7501 gtgaaccgtt tgtttttatt gtgtttggtg gagaagaata atacacttct tgcctaaatc
     7561 cagaagcccc ctttgaatgt taatttttta aaatgttaga atttggtgaa catctggaac
     7621 atgtatttgc attattttta aatttcagtg ttttaaaaag cagaccattc tggggtgtgt
     7681 ttttattgat ctttcattaa gagaaattga taggactggt tttggttttt gtttttgttt
     7741 tttttttttt ttttggtttt ctgagacagg gtttctctgt gtagccctgg ctgtcctgga
     7801 actcactttg tagaccaggc tggcctcaaa ctcagaaatc cccctgcctc tgcctcccga
     7861 gtgctgggat taaaggcgtg cgccaccaca cctggtgata ggactgtttt tttaagtgag
     7921 ctgtgtggat acaactgagt gtgtggaaac tttttcctaa aacaacattc atgtattatt
     7981 tcgatccatt tttctgtgac atttggtgca ataaactttt tgaatttatc ttgctta
//
